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3,316 results

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Page 1
Functional domains of neuromodulin (GAP-43).
Apel ED, Storm DR. Apel ED, et al. Perspect Dev Neurobiol. 1992;1(1):3-11. Perspect Dev Neurobiol. 1992. PMID: 1345683 Review.
Although neuromodulin (GAP-43, B50, F1, pp46, protein 4) was first identified over a decade ago, the physiological function(s) of the protein and the molecular mechanism(s) for its biological activities are still an area of active investigation. …
Although neuromodulin (GAP-43, B50, F1, pp46, protein 4) was first identified over a decade ago, the physiologic …
Small proteins that modulate calmodulin-dependent signal transduction: effects of PEP-19, neuromodulin, and neurogranin on enzyme activation and cellular homeostasis.
Slemmon JR, Feng B, Erhardt JA. Slemmon JR, et al. Mol Neurobiol. 2000 Aug-Dec;22(1-3):99-113. doi: 10.1385/MN:22:1-3:099. Mol Neurobiol. 2000. PMID: 11414283 Review.
Neuromodulin (GAP-43), neurogranin (RC3), and PEP-19 are small acid-stable proteins that bind calcium-poor calmodulin through a loosely conserved IQ-motif. ...The use of protein:protein interaction chromatography is also examined in the recovery …
Neuromodulin (GAP-43), neurogranin (RC3), and PEP-19 are small acid-stable proteins that bind calcium-poor calmodulin t …
Dephosphorylation of neuromodulin by calcineurin.
Liu YC, Storm DR. Liu YC, et al. J Biol Chem. 1989 Aug 5;264(22):12800-4. J Biol Chem. 1989. PMID: 2546935 Free article.
Neuromodulin (p57, GAP-43, F1, B-50) is a major neural-specific, calmodulin binding protein found in brain, spinal cord, and retina that is associated with membranes. Phosphorylation of neuromodulin by protein kinase C causes a significan …
Neuromodulin (p57, GAP-43, F1, B-50) is a major neural-specific, calmodulin binding protein found in brain, spin …
Regulation of free calmodulin levels by neuromodulin: neuron growth and regeneration.
Liu YC, Storm DR. Liu YC, et al. Trends Pharmacol Sci. 1990 Mar;11(3):107-11. doi: 10.1016/0165-6147(90)90195-e. Trends Pharmacol Sci. 1990. PMID: 2151780 Review.
Neuromodulin is a neurospecific calmodulin binding protein that is implicated in neurite extension, axonal elongation and long-term potentiation. Yuechueng Liu and Daniel Storm propose that neuromodulin binds and concentrates calmodulin on growth cone membran …
Neuromodulin is a neurospecific calmodulin binding protein that is implicated in neurite extension, axonal elongation and long …
Targeting of neuromodulin (GAP-43) fusion proteins to growth cones in cultured rat embryonic neurons.
Liu YC, Chapman ER, Storm DR. Liu YC, et al. Neuron. 1991 Mar;6(3):411-20. doi: 10.1016/0896-6273(91)90249-y. Neuron. 1991. PMID: 1825782
Neuromodulin (GAP-43) is a membrane protein that is transported to neuronal growth cones. Zuber and co-workers have proposed that the N-terminal 10 amino acid sequence of neuromodulin is sufficient to target proteins to growth cones. We demonstr …
Neuromodulin (GAP-43) is a membrane protein that is transported to neuronal growth cones. Zuber and co-workers h …
Plasma growth-associated protein 43 correlates with synaptic loss in Alzheimer's disease.
Lan G, Li B, Wang M, Barve A, Colin M, Buée L, Zhang L, Jiang M, Yang J, Li A, He Z, Zhou X, Zhu Y, Cai Y, Sun P, Liu L, Li J, Chen L, Fang L, Wang Y, Li M, Chen X, Shi D, Ye C, Fan X, Wang Q, Zhou L, Liu Z, Han Y, Wang L, Cheng G, Guan Y, Ni R, Richetin K, Xie F, Guo T. Lan G, et al. Cell Rep Med. 2025 Dec 16;6(12):102508. doi: 10.1016/j.xcrm.2025.102508. Cell Rep Med. 2025. PMID: 41406948 Free PMC article.
Synaptic loss is a hallmark of Alzheimer's disease (AD) but lacks robust blood-based biomarkers. We investigate growth-associated protein 43 (GAP-43), previously identified as a synaptic candidate in the cerebrospinal fluid (CSF). ...Plasma GAP- …
Synaptic loss is a hallmark of Alzheimer's disease (AD) but lacks robust blood-based biomarkers. We investigate growth-associated protein …
Phosphorylation of neuromodulin in rat striatum after acute and repeated, intermittent amphetamine.
Gnegy ME, Hong P, Ferrell ST. Gnegy ME, et al. Brain Res Mol Brain Res. 1993 Dec;20(4):289-98. doi: 10.1016/0169-328x(93)90055-t. Brain Res Mol Brain Res. 1993. PMID: 8114616 Free article.
Increased phosphorylation of the neural specific calmodulin-binding protein, neuromodulin (GAP-43, B-50, F1) has been demonstrated in other forms of synaptic plasticity and plays a role in neurotransmitter release. ...Anti-neuromodulin immunoblo …
Increased phosphorylation of the neural specific calmodulin-binding protein, neuromodulin (GAP-43, B-50, F1) has …
Phosphorylation of neuromodulin (GAP-43) by casein kinase II. Identification of phosphorylation sites and regulation by calmodulin.
Apel ED, Litchfield DW, Clark RH, Krebs EG, Storm DR. Apel ED, et al. J Biol Chem. 1991 Jun 5;266(16):10544-51. J Biol Chem. 1991. PMID: 1828073 Free article.
Neuromodulin (P-57, GAP-43, B-50, F-1) is a neurospecific calmodulin-binding protein believed to play a role in regulation of neurite outgrowth and neuroplasticity. Neuromodulin is phosphorylated by protein kinase C, and this phosphorylat …
Neuromodulin (P-57, GAP-43, B-50, F-1) is a neurospecific calmodulin-binding protein believed to play a role in …
Quantification of neuromodulin (GAP-43, B-50) and synapsin I in rat striata.
Iwata S, Nomoto M, Fukuda T. Iwata S, et al. Nihon Shinkei Seishin Yakurigaku Zasshi. 1999 Dec;19(5):261-6. Nihon Shinkei Seishin Yakurigaku Zasshi. 1999. PMID: 10803210
In the present study, changes in neuromodulin and synapsin I content resulting from the manipulation of lesions were quantified to elucidate the responsible pathways. ...The injection of kainic acid did not cause the content of either protein to decrease. These resu …
In the present study, changes in neuromodulin and synapsin I content resulting from the manipulation of lesions were quantified to el …
The interactions of the brain-specific calmodulin-binding protein kinase C substrate, neuromodulin (GAP 43), with membrane phospholipids.
Houbre D, Duportail G, Deloulme JC, Baudier J. Houbre D, et al. J Biol Chem. 1991 Apr 15;266(11):7121-31. J Biol Chem. 1991. PMID: 1826685 Free article.
The interaction of the brain-specific calmodulin-binding protein kinase C (PKC) substrate, neuromodulin (GAP 43), with membrane phospholipids was studied. ...Our results suggest that, in vivo, phosphorylation of neuromodulin may not only depend …
The interaction of the brain-specific calmodulin-binding protein kinase C (PKC) substrate, neuromodulin (GAP 43) …
3,316 results