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Year Number of Results
2003 1
2004 2
2006 1
2007 1
2008 1
2009 1
2010 2
2011 2
2012 1
2013 2
2014 2
2015 3
2016 2
2017 2
2019 4
2020 4
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Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis.
Philpott HT, OʼBrien M, McDougall JJ. Philpott HT, et al. Pain. 2017 Dec;158(12):2442-2451. doi: 10.1097/j.pain.0000000000001052. Pain. 2017. PMID: 28885454 Free PMC article.
Osteoarthritis (OA) is a multifactorial joint disease, which includes joint degeneration, intermittent inflammation, and peripheral neuropathy. Cannabidiol (CBD) is a noneuphoria producing constituent of cannabis that has the potential to relieve pain. The aim of th …
Osteoarthritis (OA) is a multifactorial joint disease, which includes joint degeneration, intermittent inflammation, and peripheral neuro
The Effectiveness of Topical Cannabidiol Oil in Symptomatic Relief of Peripheral Neuropathy of the Lower Extremities.
Xu DH, Cullen BD, Tang M, Fang Y. Xu DH, et al. Curr Pharm Biotechnol. 2020;21(5):390-402. doi: 10.2174/1389201020666191202111534. Curr Pharm Biotechnol. 2020. PMID: 31793418 Clinical Trial.
The efficacy of a topically delivered cannabidiol (CBD) oil in the management of neuropathic pain was examined in this four-week, randomized and placebocontrolled trial. ...The treatment product was well tolerated and may provide a more effective alternative compared to ot …
The efficacy of a topically delivered cannabidiol (CBD) oil in the management of neuropathic pain was examined in this four-week, ran …
Effects of Delta-9-Tetrahydrocannabinol and Cannabidiol on Cisplatin-Induced Neuropathy in Mice.
Harris HM, Sufka KJ, Gul W, ElSohly MA. Harris HM, et al. Planta Med. 2016 Aug;82(13):1169-72. doi: 10.1055/s-0042-106303. Epub 2016 May 23. Planta Med. 2016. PMID: 27214593
Cisplatin produced a reduction in g of force indicative of neuropathy that was attenuated by gabapentin, tetrahydocannabinol, and cannabidiol but not prevented by either cannabinoid. These data demonstrate that each of the major constituents of Sativex alone can ach …
Cisplatin produced a reduction in g of force indicative of neuropathy that was attenuated by gabapentin, tetrahydocannabinol, and …
An Update of Current Cannabis-Based Pharmaceuticals in Pain Medicine.
Urits I, Borchart M, Hasegawa M, Kochanski J, Orhurhu V, Viswanath O. Urits I, et al. Pain Ther. 2019 Jun;8(1):41-51. doi: 10.1007/s40122-019-0114-4. Epub 2019 Feb 5. Pain Ther. 2019. PMID: 30721403 Free PMC article. Review.
The cannabidiol oral solution Epidiolex®, which is available in the USA, is indicated for management of refractory epilepsy but may offer therapeutic relief to chronic pain conditions as well. Current investigative drugs, such as those developed by Cara Therapeutics and Zy …
The cannabidiol oral solution Epidiolex®, which is available in the USA, is indicated for management of refractory epilepsy but may o …
Single and combined effects of Δ(9) -tetrahydrocannabinol and cannabidiol in a mouse model of chemotherapy-induced neuropathic pain.
King KM, Myers AM, Soroka-Monzo AJ, Tuma RF, Tallarida RJ, Walker EA, Ward SJ. King KM, et al. Br J Pharmacol. 2017 Sep;174(17):2832-2841. doi: 10.1111/bph.13887. Epub 2017 Jul 27. Br J Pharmacol. 2017. PMID: 28548225 Free PMC article.
BACKGROUND AND PURPOSE: The non-psychoactive phytocannabinoid cannabidiol (CBD) can affect the pharmacological effects of Δ(9) -tetrahydrocannabinol (THC). ...CONCLUSIONS AND IMPLICATIONS: CBD may be potent and effective at preventing the development of chemotherapy-induce …
BACKGROUND AND PURPOSE: The non-psychoactive phytocannabinoid cannabidiol (CBD) can affect the pharmacological effects of Δ(9) -tetra …
The non-psychoactive cannabis constituent cannabidiol is an orally effective therapeutic agent in rat chronic inflammatory and neuropathic pain.
Costa B, Trovato AE, Comelli F, Giagnoni G, Colleoni M. Costa B, et al. Eur J Pharmacol. 2007 Feb 5;556(1-3):75-83. doi: 10.1016/j.ejphar.2006.11.006. Epub 2006 Nov 10. Eur J Pharmacol. 2007. PMID: 17157290
Cannabidiol, the major psycho-inactive component of cannabis, has substantial anti-inflammatory and immunomodulatory effects. ...The results indicate a potential for therapeutic use of cannabidiol in chronic painful states....
Cannabidiol, the major psycho-inactive component of cannabis, has substantial anti-inflammatory and immunomodulatory effects. ...The
Role of the endocannabinoid system in diabetes and diabetic complications.
Gruden G, Barutta F, Kunos G, Pacher P. Gruden G, et al. Br J Pharmacol. 2016 Apr;173(7):1116-27. doi: 10.1111/bph.13226. Epub 2015 Aug 20. Br J Pharmacol. 2016. PMID: 26076890 Free PMC article. Review.
In this review, we provide an update on the contribution of the ECS to the pathogenesis of diabetes and diabetic microvascular (retinopathy, nephropathy and neuropathy) and cardiovascular complications. ...
In this review, we provide an update on the contribution of the ECS to the pathogenesis of diabetes and diabetic microvascular (retinopathy, …
A multicentre, open-label, follow-on study to assess the long-term maintenance of effect, tolerance and safety of THC/CBD oromucosal spray in the management of neuropathic pain.
Hoggart B, Ratcliffe S, Ehler E, Simpson KH, Hovorka J, Lejčko J, Taylor L, Lauder H, Serpell M. Hoggart B, et al. J Neurol. 2015 Jan;262(1):27-40. doi: 10.1007/s00415-014-7502-9. Epub 2014 Sep 30. J Neurol. 2015. PMID: 25270679 Clinical Trial.
The long-term efficacy of delta-9-tetrahydrocannabinol (THC)/cannabidiol (CBD) oromucosal spray was investigated in this 38-week open-label extension study. ...
The long-term efficacy of delta-9-tetrahydrocannabinol (THC)/cannabidiol (CBD) oromucosal spray was investigated in this 38-week open …
Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabetic rats via serotonergic system activation through 5-HT1A receptors.
Jesus CHA, Redivo DDB, Gasparin AT, Sotomaior BB, de Carvalho MC, Genaro K, Zuardi AW, Hallak JEC, Crippa JA, Zanoveli JM, da Cunha JM. Jesus CHA, et al. Brain Res. 2019 Jul 15;1715:156-164. doi: 10.1016/j.brainres.2019.03.014. Epub 2019 Mar 18. Brain Res. 2019. PMID: 30898678
Cannabidiol (CBD) has shown promising results in painful conditions. Then, we aimed to investigate the potential antinociceptive effect of CBD over the mechanical allodynia in streptozotocin-induced diabetic (DBT) rats, as well as its involved mechanisms. ...Taken together
Cannabidiol (CBD) has shown promising results in painful conditions. Then, we aimed to investigate the potential antinociceptive effe
A double-blind, placebo-controlled, crossover pilot trial with extension using an oral mucosal cannabinoid extract for treatment of chemotherapy-induced neuropathic pain.
Lynch ME, Cesar-Rittenberg P, Hohmann AG. Lynch ME, et al. J Pain Symptom Manage. 2014 Jan;47(1):166-73. doi: 10.1016/j.jpainsymman.2013.02.018. Epub 2013 Jun 4. J Pain Symptom Manage. 2014. PMID: 23742737 Free article. Clinical Trial.
Chemotherapeutic neuropathy responds poorly to conventional treatments, and there is an urgent medical need for new treatments. Recent preclinical studies demonstrate that cannabinoid agonists suppress established chemotherapy-evoked neuropathy. OBJECTIVES: This was …
Chemotherapeutic neuropathy responds poorly to conventional treatments, and there is an urgent medical need for new treatments. Recen …
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