Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2005 1
2010 1
2011 1
2012 1
2013 1
2019 1
2020 1
2021 3
2022 1
2023 1
2024 1
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

11 results

Results by year

Filters applied: . Clear all
Page 1
New insights in endosomal dynamics and AMPA receptor trafficking.
van der Sluijs P, Hoogenraad CC. van der Sluijs P, et al. Semin Cell Dev Biol. 2011 Jul;22(5):499-505. doi: 10.1016/j.semcdb.2011.06.008. Epub 2011 Aug 6. Semin Cell Dev Biol. 2011. PMID: 21843653 Review.
Dendritic spines are important sites for AMPA receptor trafficking and contain the basic components of endosomal recycling. On induction of synaptic plasticity, internalized AMPA receptors undergo endosomal sorting and cycle through early endosomes …
Dendritic spines are important sites for AMPA receptor trafficking and contain the basic components of endosomal recycling. On …
The Coordination of Local Translation, Membranous Organelle Trafficking, and Synaptic Plasticity in Neurons.
Rajgor D, Welle TM, Smith KR. Rajgor D, et al. Front Cell Dev Biol. 2021 Jul 14;9:711446. doi: 10.3389/fcell.2021.711446. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34336865 Free PMC article. Review.
It is now well-established that local translation of numerous synaptic proteins is essential for many forms of synaptic plasticity, and much work has gone into deciphering the strategies that neurons use to regulate activity-dependent protein synthesis. ...This includes th …
It is now well-established that local translation of numerous synaptic proteins is essential for many forms of synaptic plasticity, a …
Diminished Neuronal ESCRT-0 Function Exacerbates AMPA Receptor Derangement and Accelerates Prion-Induced Neurodegeneration.
Lawrence JA, Aguilar-Calvo P, Ojeda-Juárez D, Khuu H, Soldau K, Pizzo DP, Wang J, Malik A, Shay TF, Sullivan EE, Aulston B, Song SM, Callender JA, Sanchez H, Geschwind MD, Roy S, Rissman RA, Trejo J, Tanaka N, Wu C, Chen X, Patrick GN, Sigurdson CJ. Lawrence JA, et al. J Neurosci. 2023 May 24;43(21):3970-3984. doi: 10.1523/JNEUROSCI.1878-22.2023. Epub 2023 Apr 5. J Neurosci. 2023. PMID: 37019623 Free PMC article.
We found that prion-affected human and mouse brain showed a marked reduction in Hrs and STAM1 (ESCRT-0), which route ubiquitinated membrane proteins from early endosomes into MVBs. To determine how the reduction in ESCRT-0 impacts prion conversion and cellula …
We found that prion-affected human and mouse brain showed a marked reduction in Hrs and STAM1 (ESCRT-0), which route ubiquitinated membra …
Stargazin regulates AMPA receptor trafficking through adaptor protein complexes during long-term depression.
Matsuda S, Kakegawa W, Budisantoso T, Nomura T, Kohda K, Yuzaki M. Matsuda S, et al. Nat Commun. 2013;4:2759. doi: 10.1038/ncomms3759. Nat Commun. 2013. PMID: 24217640 Free article.
Inhibiting the stargazin-AP-2 interaction disrupts NMDA-induced AMPA receptor endocytosis, and inhibiting that of stargazin-AP-3A abrogates the late endosomal/lysosomal trafficking of AMPA receptors, thereby upregulating receptor recycling to th …
Inhibiting the stargazin-AP-2 interaction disrupts NMDA-induced AMPA receptor endocytosis, and inhibiting that of stargazin-AP-3A abr …
Early Chronic Fluoxetine Treatment of Ts65Dn Mice Rescues Synaptic Vesicular Deficits and Prevents Aberrant Proteomic Alterations.
Fatemi SH, Otte ED, Folsom TD, Eschenlauer AC, Roper RJ, Aman JW, Thuras PD. Fatemi SH, et al. Genes (Basel). 2024 Apr 3;15(4):452. doi: 10.3390/genes15040452. Genes (Basel). 2024. PMID: 38674386 Free PMC article.
Proteomic analysis of trisomic synaptic fractions revealed significant downregulation of proteins involved in synaptic vesicular traffic, including vesicular endocytosis (CLTA, CLTB, CLTC), synaptic assembly and maturation (EXOC1, EXOC3, EXOC8), anterograde axonal trans …
Proteomic analysis of trisomic synaptic fractions revealed significant downregulation of proteins involved in synaptic vesicular traf …
A novel synaptopathy-defective synaptic vesicle protein trafficking in the mutant CHMP2B mouse model of frontotemporal dementia.
Clayton EL, Bonnycastle K, Isaacs AM, Cousin MA, Schorge S. Clayton EL, et al. J Neurochem. 2022 Feb;160(3):412-425. doi: 10.1111/jnc.15551. Epub 2021 Dec 11. J Neurochem. 2022. PMID: 34855215
Mutations in the ESCRT-III subunit CHMP2B cause frontotemporal dementia (FTD) and lead to impaired endolysosomal trafficking and lysosomal storage pathology in neurons. We investigated the effect of mutant CHMP2B on synaptic pathology, as ESCRT function was recently implic …
Mutations in the ESCRT-III subunit CHMP2B cause frontotemporal dementia (FTD) and lead to impaired endolysosomal trafficking and lysosoma …
Arfgef1 haploinsufficiency in mice alters neuronal endosome composition and decreases membrane surface postsynaptic GABA(A) receptors.
Teoh J, Subramanian N, Pero ME, Bartolini F, Amador A, Kanber A, Williams D, Petri S, Yang M, Allen AS, Beal J, Haut SR, Frankel WN. Teoh J, et al. Neurobiol Dis. 2020 Feb;134:104632. doi: 10.1016/j.nbd.2019.104632. Epub 2019 Oct 31. Neurobiol Dis. 2020. PMID: 31678406 Free PMC article.
In primary hippocampal neuron culture, dendritic surface and synaptic but not total GABA(A) receptors (GABA(A)R) are reduced in Arfgef1(fs/+) neurons with an accompanying decrease in the number of GABA(A)R-containing recycling endosomes in cell body. Arfgef1(fs/+) n …
In primary hippocampal neuron culture, dendritic surface and synaptic but not total GABA(A) receptors (GABA(A)R) are reduced in Arfge …
Subunit-dependent and subunit-independent rules of AMPA receptor trafficking during chemical long-term depression in hippocampal neurons.
Matsuda S, Yuzaki M. Matsuda S, et al. J Biol Chem. 2021 Aug;297(2):100949. doi: 10.1016/j.jbc.2021.100949. Epub 2021 Jul 10. J Biol Chem. 2021. PMID: 34252460 Free PMC article.
Both processes are primarily mediated by neuronal activity-induced transport of postsynaptic AMPA-type glutamate receptors (AMPARs). While AMPAR subunits and their specific phosphorylation sites mediate differential AMPAR trafficking, LTP and LTD could also o …
Both processes are primarily mediated by neuronal activity-induced transport of postsynaptic AMPA-type glutamate receptors …
Regulated lysosomal trafficking as a mechanism for regulating GABAA receptor abundance at synapses in Caenorhabditis elegans.
Davis KM, Sturt BL, Friedmann AJ, Richmond JE, Bessereau JL, Grant BD, Bamber BA. Davis KM, et al. Mol Cell Neurosci. 2010 Aug;44(4):307-17. doi: 10.1016/j.mcn.2010.04.002. Epub 2010 Apr 18. Mol Cell Neurosci. 2010. PMID: 20403442
Mutants with defective lysosome function (cup-5) show elevated GABA(A) receptor levels at synapses prior to muscimol exposure. ...These findings suggest that chronic agonist exposure increases endocytosis and lysosomal trafficking of GABA(A) receptors, …
Mutants with defective lysosome function (cup-5) show elevated GABA(A) receptor levels at synapses prior to muscimol exposure. …
The balance between receptor recycling and trafficking toward lysosomes determines synaptic strength during long-term depression.
Fernández-Monreal M, Brown TC, Royo M, Esteban JA. Fernández-Monreal M, et al. J Neurosci. 2012 Sep 19;32(38):13200-5. doi: 10.1523/JNEUROSCI.0061-12.2012. J Neurosci. 2012. PMID: 22993436 Free PMC article.
The strength of excitatory synaptic transmission depends partly on the number of AMPA receptors (AMPARs) at the postsynaptic surface and, thus, can be modulated by membrane trafficking events. ...This sorting decision is related to the phosphorylation status …
The strength of excitatory synaptic transmission depends partly on the number of AMPA receptors (AMPARs) at the postsynaptic s …
11 results