Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
2003 1
2004 1
2006 1
2007 2
2008 2
2009 2
2011 1
2012 1
2013 3
2014 2
2015 3
2016 2
2017 4
2018 1
2019 2
2020 3
2021 6
2022 2
2023 4
2025 4
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

40 results

Results by year

Filters applied: . Clear all
Page 1
Exercise therapy to prevent and treat Alzheimer's disease.
Pahlavani HA. Pahlavani HA. Front Aging Neurosci. 2023 Aug 4;15:1243869. doi: 10.3389/fnagi.2023.1243869. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37600508 Free PMC article. Review.
Alzheimer's disease (AD) is a progressive neurodegenerative disease in the elderly with dementia, memory loss, and severe cognitive impairment that imposes high medical costs on individuals. The causes of AD include increased deposition of amyloid beta (Abeta) and phosphor …
Alzheimer's disease (AD) is a progressive neurodegenerative disease in the elderly with dementia, memory loss, and severe cognitive i …
The involvement of BDNF, NGF and GDNF in aging and Alzheimer's disease.
Budni J, Bellettini-Santos T, Mina F, Garcez ML, Zugno AI. Budni J, et al. Aging Dis. 2015 Oct 1;6(5):331-41. doi: 10.14336/AD.2015.0825. eCollection 2015 Sep. Aging Dis. 2015. PMID: 26425388 Free PMC article. Review.
Cognitive deficit is related to alterations of neurotrophic factors level such as brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) and glial cell-derived neurotrophic …
Cognitive deficit is related to alterations of neurotrophic factors level such as brain-derived neurot …
FTO inhibition mitigates high-fat diet-induced metabolic disturbances and cognitive decline in SAMP8 mice.
Irisarri A, Corral A, Perez-Salvador N, Bellver-Sanchis A, Ribalta-Vilella M, Bentanachs R, Alegret M, Laguna JC, Barroso E, Palomer X, Ortuño-Sahagún D, Vázquez-Carrera M, Pallàs M, Herrero L, Griñán-Ferré C. Irisarri A, et al. Mol Med. 2025 Feb 21;31(1):73. doi: 10.1186/s10020-025-01126-4. Mol Med. 2025. PMID: 39984825 Free PMC article.
Notably, enhanced leptin signaling was observed through increased expression of immediate early genes (Arc, Fos) and the transcription factor Stat3. Improved synaptic plasticity was evident, as shown by increased levels of neurotrophic factors (Bdnf, …
Notably, enhanced leptin signaling was observed through increased expression of immediate early genes (Arc, Fos) and the transcription fa …
Western Diet and Cognitive Decline: A Hungarian Perspective-Implications for the Design of the Semmelweis Study.
Lehoczki A, Csípő T, Lipécz Á, Major D, Fazekas-Pongor V, Csík B, Mózes N, Fehér Á, Dósa N, Árva D, Pártos K, Kaposvári C, Horváth K, Varga P, Fekete M. Lehoczki A, et al. Nutrients. 2025 Jul 27;17(15):2446. doi: 10.3390/nu17152446. Nutrients. 2025. PMID: 40806031 Free PMC article. Review.
Modifiable lifestyle factors-especially dietary habits-play a critical role in brain aging and cognitive decline. ...In contrast, adherence to Mediterranean dietary patterns-particularly those rich in polyphenols from extra virgin olive oil and moderate red w …
Modifiable lifestyle factors-especially dietary habits-play a critical role in brain aging and cognitive decline. ...In …
Hormetic pathways in environmental enrichment in animal models and humans.
Hanampa-Maquera M, Lourenço RC, Bailey A, Camarini R. Hanampa-Maquera M, et al. Prog Brain Res. 2025;295:189-227. doi: 10.1016/bs.pbr.2025.05.007. Epub 2025 May 20. Prog Brain Res. 2025. PMID: 40769639 Review.
Since Hebb's pioneering work on neuronal ensembles, research has demonstrated that EE enhances neurogenesis, synaptic plasticity, and neurotrophic factor expression (BDNF and NGF) while modulating inflammatory processes, epigenetic pathways, and metabo …
Since Hebb's pioneering work on neuronal ensembles, research has demonstrated that EE enhances neurogenesis, synaptic plasticity, and neu …
Muscle Injury Induces Postoperative Cognitive Dysfunction.
Guéniot L, Lepere V, De Medeiros GF, Danckaert A, Flamant P, Le Dudal M, Langeron O, Goossens PL, Chrétien F, Jouvion G. Guéniot L, et al. Sci Rep. 2020 Feb 17;10(1):2768. doi: 10.1038/s41598-020-59639-3. Sci Rep. 2020. PMID: 32066806 Free PMC article.
Postoperative cognitive dysfunction (POCD) is a major complication affecting patients of any age undergoing surgery. ...We highlighted: alteration of short- and long-term memory after muscle regeneration, wide microglial reactivity in the brain, including hippocampus area, …
Postoperative cognitive dysfunction (POCD) is a major complication affecting patients of any age undergoing surgery. ...We highlighte …
Innovative Therapy for Alzheimer's Disease-With Focus on Biodelivery of NGF.
Mitra S, Behbahani H, Eriksdotter M. Mitra S, et al. Front Neurosci. 2019 Feb 5;13:38. doi: 10.3389/fnins.2019.00038. eCollection 2019. Front Neurosci. 2019. PMID: 30804738 Free PMC article. Review.
Various reports link AD progression with declining activity of cholinergic neurons in basal forebrain. The neurotrophic molecule, nerve growth factor (NGF), plays a major role in the maintenance of cholinergic neurons integrity and function, bot …
Various reports link AD progression with declining activity of cholinergic neurons in basal forebrain. The neurotrophic molecule, …
FTO (fat-mass and obesity-associated protein) deficiency aggravates age-dependent depression-like behaviors and cognitive impairment.
Li M, Yang Y, Chen T, Luo Y, Zhang Y, Liu H, Maes M. Li M, et al. Behav Brain Funct. 2025 Jun 15;21(1):18. doi: 10.1186/s12993-025-00280-3. Behav Brain Funct. 2025. PMID: 40518522 Free PMC article.
Chronic stress-induced depression-like behavior and cognitive impairment worsened after the FTO-KD intervention. In the hippocampus of 3- and 12-month-old mice, CUMS induced the downregulation of FTO, nerve growth factor (NGF), reelin, and synap …
Chronic stress-induced depression-like behavior and cognitive impairment worsened after the FTO-KD intervention. In the hippocampus o …
Polyphenols' Impact on Selected Biomarkers of Brain Aging in Healthy Middle-Aged and Elderly Subjects: A Review of Clinical Trials.
Ziegler T, Tsiountsioura M, Meixner-Goetz L, Cvirn G, Lamprecht M. Ziegler T, et al. Nutrients. 2023 Aug 29;15(17):3770. doi: 10.3390/nu15173770. Nutrients. 2023. PMID: 37686802 Free PMC article. Review.
Therefore, biomarkers to detect manifestations of brain aging early and interventions to slow down its pace are of great interest. In the last years, the importance of the neurotrophins brain-derived neurotrophic factor (BDNF) and nerv …
Therefore, biomarkers to detect manifestations of brain aging early and interventions to slow down its pace are of great interest. In …
Cholinotrophic molecular substrates of mild cognitive impairment in the elderly.
Mufson EJ, Counts SE, Fahnestock M, Ginsberg SD. Mufson EJ, et al. Curr Alzheimer Res. 2007 Sep;4(4):340-50. doi: 10.2174/156720507781788855. Curr Alzheimer Res. 2007. PMID: 17908035 Review.
Cholinergic nucleus basalis (NB) neurons provide the major cholinergic innervation to the cortical mantle, are selectively vulnerable in late stage Alzheimer's disease (AD) and require the neurotrophin, nerve growth factor (NGF) and its receptors (TrkA …
Cholinergic nucleus basalis (NB) neurons provide the major cholinergic innervation to the cortical mantle, are selectively vulnerable in lat …
40 results