Increased antitumor efficacy of PD-1-deficient melanoma-specific human lymphocytes.
J Immunother Cancer. 2020 Jan;8(1):e000311. doi: 10.1136/jitc-2019-000311.
J Immunother Cancer. 2020.
PMID: 32001504
Free PMC article.
We cloned edited T cell populations and validated PDCD1 editing through sequencing and cytometry in each T cell clone, together with T-cell receptor (TCR) chain's sequencing. We also performed whole transcriptomic analyses on wild-type (WT) and edited T cell clones. ...
We cloned edited T cell populations and validated PDCD1 editing through sequencing and cytometry in each T cell clone, together with T-cell …