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Year Number of Results
1985 1
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234 results

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Page 1
Lipoprotein(a) and its Significance in Cardiovascular Disease: A Review.
Duarte Lau F, Giugliano RP. Duarte Lau F, et al. JAMA Cardiol. 2022 Jul 1;7(7):760-769. doi: 10.1001/jamacardio.2022.0987. JAMA Cardiol. 2022. PMID: 35583875 Review.
IMPORTANCE: Lipoprotein(a) (Lp[a]) is a low-density lipoprotein (LDL) cholesterol-like particle bound to apolipoprotein(a). ...The ineffectiveness of lifestyle modification, statins, and ezetimibe to lower Lp(a); the modest Lp(a) reduction with proprotein convertase …
IMPORTANCE: Lipoprotein(a) (Lp[a]) is a low-density lipoprotein (LDL) cholesterol-like particle bound to apolipoprotein(a). .. …
Lipoprotein(a) and panvascular disease.
Xu R, Wang Z, Dong J, Yu M, Zhou Y. Xu R, et al. Lipids Health Dis. 2025 May 24;24(1):186. doi: 10.1186/s12944-025-02600-y. Lipids Health Dis. 2025. PMID: 40413492 Free PMC article. Review.
This perspective enables a more integrated understanding of disease processes across organ systems that are often studied in isolation. Lipoprotein(a) [Lp(a)] is a genetically regulated, low-density lipoprotein (LDL)-like particle that has garnered increasing attent …
This perspective enables a more integrated understanding of disease processes across organ systems that are often studied in isolation. L …
Lipoprotein(a) as a cardiovascular risk factor: current status.
Nordestgaard BG, Chapman MJ, Ray K, Borén J, Andreotti F, Watts GF, Ginsberg H, Amarenco P, Catapano A, Descamps OS, Fisher E, Kovanen PT, Kuivenhoven JA, Lesnik P, Masana L, Reiner Z, Taskinen MR, Tokgözoglu L, Tybjærg-Hansen A; European Atherosclerosis Society Consensus Panel. Nordestgaard BG, et al. Eur Heart J. 2010 Dec;31(23):2844-53. doi: 10.1093/eurheartj/ehq386. Epub 2010 Oct 21. Eur Heart J. 2010. PMID: 20965889 Free PMC article.
AIMS: The aims of the study were, first, to critically evaluate lipoprotein(a) [Lp(a)] as a cardiovascular risk factor and, second, to advise on screening for elevated plasma Lp(a), on desirable levels, and on therapeutic strategies. ...As a secondary priority after …
AIMS: The aims of the study were, first, to critically evaluate lipoprotein(a) [Lp(a)] as a cardiovascular risk factor and, se …
Lipoprotein(a) as a Risk Factor for Cardiovascular Diseases: Pathophysiology and Treatment Perspectives.
Vinci P, Di Girolamo FG, Panizon E, Tosoni LM, Cerrato C, Pellicori F, Altamura N, Pirulli A, Zaccari M, Biasinutto C, Roni C, Fiotti N, Schincariol P, Mangogna A, Biolo G. Vinci P, et al. Int J Environ Res Public Health. 2023 Sep 6;20(18):6721. doi: 10.3390/ijerph20186721. Int J Environ Res Public Health. 2023. PMID: 37754581 Free PMC article. Review.
Cardiovascular disease (CVD) is still a leading cause of morbidity and mortality, despite all the progress achieved as regards to both prevention and treatment. Having high levels of lipoprotein(a) [Lp(a)] is a risk factor for cardiovascular disease that operates in …
Cardiovascular disease (CVD) is still a leading cause of morbidity and mortality, despite all the progress achieved as regards to both preve …
Role of lipoprotein(a) in atherosclerotic cardiovascular disease: A review of current and emerging therapies.
Alhomoud IS, Talasaz A, Mehta A, Kelly MS, Sisson EM, Bucheit JD, Brown R, Dixon DL. Alhomoud IS, et al. Pharmacotherapy. 2023 Oct;43(10):1051-1063. doi: 10.1002/phar.2851. Epub 2023 Jul 26. Pharmacotherapy. 2023. PMID: 37464942 Review.
Lipoprotein(a), or Lp(a), is structurally like low-density lipoprotein (LDL) but differs in that it contains glycoprotein apolipoprotein(a) [apo(a)]. ...Alirocumab, evolocumab, and inclisiran reduce Lp(a) levels by 20-25%, yet the clinical implications of this reduc …
Lipoprotein(a), or Lp(a), is structurally like low-density lipoprotein (LDL) but differs in that it contains glycoprotein apol …
Niacin and lipoprotein(a): facts, uncertainties, and clinical considerations.
Scanu AM, Bamba R. Scanu AM, et al. Am J Cardiol. 2008 Apr 17;101(8A):44B-47B. doi: 10.1016/j.amjcard.2008.02.031. Am J Cardiol. 2008. PMID: 18375241 Review.
In high doses, niacin has also been reported to lower the plasma level of lipoprotein(a) (Lp[a]). However, the published research on the subject suffers from a lack of uniformity regarding patient selection, drug dose, length of administration, and methods fo …
In high doses, niacin has also been reported to lower the plasma level of lipoprotein(a) (Lp[a]). However, the publishe …
Lipoprotein A.
Farzam K, Zubair M, Senthilkumaran S. Farzam K, et al. 2024 Feb 27. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2024 Feb 27. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 34033383 Free Books & Documents.
Lipoprotein(a), or Lp(a), is an established and genetically determined risk factor for atherosclerosis, coronary artery disease, stroke, thrombosis, and aortic stenosis. ...While certain medications such as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhib …
Lipoprotein(a), or Lp(a), is an established and genetically determined risk factor for atherosclerosis, coronary artery diseas …
Oxidized phospholipids in cardiovascular disease.
Tsimikas S, Witztum JL. Tsimikas S, et al. Nat Rev Cardiol. 2024 Mar;21(3):170-191. doi: 10.1038/s41569-023-00937-4. Epub 2023 Oct 17. Nat Rev Cardiol. 2024. PMID: 37848630 Review.
When initially conceptualized, OxPL-apoB measurement in plasma was expected to reflect the concentration of minimally oxidized LDL, but, surprisingly, it correlated more strongly with plasma lipoprotein(a) (Lp(a)) levels. Indeed, experimental and clinical studies sh …
When initially conceptualized, OxPL-apoB measurement in plasma was expected to reflect the concentration of minimally oxidized LDL, but, sur …
Effect of lipid-lowering therapies on lipoprotein(a) levels: a comprehensive meta-analysis of randomized controlled trials.
Xie S, Galimberti F, Olmastroni E, Carugo S, Catapano AL, Casula M; META-LIPID Group. Xie S, et al. Atherosclerosis. 2025 Sep;408:120420. doi: 10.1016/j.atherosclerosis.2025.120420. Epub 2025 Jul 3. Atherosclerosis. 2025. PMID: 40618457
BACKGROUND AND AIMS: Lipoprotein (a) [Lp(a)] is an independent and causal risk factor for atherosclerotic cardiovascular disease. ...CONCLUSIONS: Among available LLTs, PCSK9mAbs, inclisiran, CETPi, and niacin significantly decreased Lp(a) levels. Further rese …
BACKGROUND AND AIMS: Lipoprotein (a) [Lp(a)] is an independent and causal risk factor for atherosclerotic cardiovascular disea …
Lipoprotein(a)-antisense therapy.
Vogt A. Vogt A. Clin Res Cardiol Suppl. 2019 Apr;14(Suppl 1):51-56. doi: 10.1007/s11789-019-00096-2. Clin Res Cardiol Suppl. 2019. PMID: 30859384
Elevated levels of lipoprotein(a) (Lp(a)) contribute to the risk of early and severe cardiovascular disease (CVD) and Lp(a) is acknowledged as a risk factor to be included in risk assessment. ...None of the available agents is indicated to lower Lp(a). Lip …
Elevated levels of lipoprotein(a) (Lp(a)) contribute to the risk of early and severe cardiovascular disease (CVD) and Lp(a) is …
234 results