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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1939 1
1945 2
1946 7
1947 13
1948 19
1949 21
1950 104
1951 77
1952 149
1953 126
1954 172
1955 156
1956 186
1957 185
1958 185
1959 97
1960 56
1961 66
1962 106
1963 549
1964 765
1965 799
1966 771
1967 887
1968 1012
1969 1080
1970 1094
1971 1155
1972 1292
1973 1092
1974 1019
1975 1164
1976 1072
1977 1004
1978 893
1979 895
1980 998
1981 816
1982 926
1983 853
1984 989
1985 946
1986 924
1987 876
1988 845
1989 953
1990 955
1991 946
1992 974
1993 978
1994 1014
1995 1085
1996 1062
1997 1113
1998 1100
1999 1180
2000 1131
2001 1231
2002 1264
2003 1291
2004 1349
2005 1478
2006 1397
2007 1503
2008 1638
2009 1623
2010 1707
2011 1832
2012 2010
2013 2320
2014 2198
2015 2165
2016 2180
2017 2200
2018 2269
2019 2358
2020 2514
2021 1317
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72,489 results
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Page 1
Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration.
Mukherjee S, Chellappa K, Moffitt A, Ndungu J, Dellinger RW, Davis JG, Agarwal B, Baur JA. Mukherjee S, et al. Hepatology. 2017 Feb;65(2):616-630. doi: 10.1002/hep.28912. Epub 2016 Dec 24. Hepatology. 2017. PMID: 27809334 Free PMC article.
The regenerative capacity of the liver is essential for recovery from surgical resection or injuries induced by trauma or toxins. During liver regeneration, the concentration of nicotinamide adenine dinucleotide (NAD) falls, at least in part due to met …
The regenerative capacity of the liver is essential for recovery from surgical resection or injuries induced by trauma or toxins. During liv …
Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes.
Braidy N, Berg J, Clement J, Khorshidi F, Poljak A, Jayasena T, Grant R, Sachdev P. Braidy N, et al. Antioxid Redox Signal. 2019 Jan 10;30(2):251-294. doi: 10.1089/ars.2017.7269. Epub 2018 May 11. Antioxid Redox Signal. 2019. PMID: 29634344 Free PMC article. Review.
Significance: Nicotinamide adenine dinucleotide (NAD(+)) is an essential pyridine nucleotide that serves as an essential cofactor and substrate for a number of critical cellular processes involved in oxidative phosphorylation and ATP production, DNA re …
Significance: Nicotinamide adenine dinucleotide (NAD(+)) is an essential pyridine nucleotide that serves as an e …
Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors.
Lu W, Wang L, Chen L, Hui S, Rabinowitz JD. Lu W, et al. Antioxid Redox Signal. 2018 Jan 20;28(3):167-179. doi: 10.1089/ars.2017.7014. Epub 2017 Jul 19. Antioxid Redox Signal. 2018. PMID: 28497978 Free PMC article.
AIMS: Accurate analysis of dinucleotide redox cofactors nicotinamide adenine dinucleotide phosphate reduced (NADPH), nicotinamide adenine dinucleotide phosphate (NADP(+)), nicotinamide adenine dinucleotide redu …
AIMS: Accurate analysis of dinucleotide redox cofactors nicotinamide adenine dinucleotide phosphate reduced (NAD …
Nicotinamide adenine dinucleotide (NAD+): essential redox metabolite, co-substrate and an anti-cancer and anti-ageing therapeutic target.
Griffiths HBS, Williams C, King SJ, Allison SJ. Griffiths HBS, et al. Biochem Soc Trans. 2020 Jun 30;48(3):733-744. doi: 10.1042/BST20190033. Biochem Soc Trans. 2020. PMID: 32573651 Review.
Nicotinamide adenine dinucleotide (NAD+) and its reduced form NADH are essential coupled redox metabolites that primarily promote cellular oxidative (catabolic) metabolic reactions. ...Whilst their vital activity consumes NAD+ which is cleaved t
Nicotinamide adenine dinucleotide (NAD+) and its reduced form NADH are essential coupled redox metabolites that
Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditions.
Hosseini L, Vafaee MS, Mahmoudi J, Badalzadeh R. Hosseini L, et al. Biogerontology. 2019 Aug;20(4):381-395. doi: 10.1007/s10522-019-09805-6. Epub 2019 Mar 5. Biogerontology. 2019. PMID: 30838484 Review.
Nicotinamide adenine dinucleotide (NAD(+)) has been described as central coenzyme of redox reactions and is a key regulator of stress resistance and longevity. ...The majority of studies have shown that restoring of NAD(+) using supplementation
Nicotinamide adenine dinucleotide (NAD(+)) has been described as central coenzyme of redox reactions and is a ke
Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration.
Pehar M, Harlan BA, Killoy KM, Vargas MR. Pehar M, et al. Antioxid Redox Signal. 2018 Jun 20;28(18):1652-1668. doi: 10.1089/ars.2017.7145. Epub 2017 Jun 27. Antioxid Redox Signal. 2018. PMID: 28548540 Free PMC article. Review.
SIGNIFICANCE: Nicotinamide adenine dinucleotide (NAD(+)) participates in redox reactions and NAD(+)-dependent signaling processes, which involve the cleavage of NAD(+) coupled to posttranslational modifications of proteins or the producti …
SIGNIFICANCE: Nicotinamide adenine dinucleotide (NAD(+)) participates in redox reactions and NAD(+)-depen …
Therapeutic potential of nicotinamide adenine dinucleotide (NAD).
Arenas-Jal M, Suñé-Negre JM, García-Montoya E. Arenas-Jal M, et al. Eur J Pharmacol. 2020 Jul 15;879:173158. doi: 10.1016/j.ejphar.2020.173158. Epub 2020 Apr 28. Eur J Pharmacol. 2020. PMID: 32360833 Review.
Nicotinamide adenine nucleotide (NAD) is a small ubiquitous hydrophilic cofactor that participates in several aspects of cellular metabolism. ...In fact, different approaches to replenish or increase NAD levels have been tested, including enhancement o
Nicotinamide adenine nucleotide (NAD) is a small ubiquitous hydrophilic cofactor that participates in several aspects o
Nicotinamide adenine dinucleotide and its related precursors for the treatment of Alzheimer's disease.
Braidy N, Grant R, Sachdev PS. Braidy N, et al. Curr Opin Psychiatry. 2018 Mar;31(2):160-166. doi: 10.1097/YCO.0000000000000394. Curr Opin Psychiatry. 2018. PMID: 29232252 Review.
PURPOSE OF REVIEW: The current review discusses the biology and metabolism of the essential pyridine nucleotide nicotinamide adenine dinucleotide (NAD+) in the central nervous system. We also review recent work suggesting important neuroprotective effe …
PURPOSE OF REVIEW: The current review discusses the biology and metabolism of the essential pyridine nucleotide nicotinamide adeni
Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence.
Rajman L, Chwalek K, Sinclair DA. Rajman L, et al. Cell Metab. 2018 Mar 6;27(3):529-547. doi: 10.1016/j.cmet.2018.02.011. Cell Metab. 2018. PMID: 29514064 Free PMC article. Review.
Nicotinamide adenine dinucleotide (NAD), the cell's hydrogen carrier for redox enzymes, is well known for its role in redox reactions. More recently, it has emerged as a signaling molecule. By modulating NAD(+)-sensing enzymes, NAD(+) con
Nicotinamide adenine dinucleotide (NAD), the cell's hydrogen carrier for redox enzymes, is well known for its ro
PPARgamma-Coactivator-1alpha, Nicotinamide Adenine Dinucleotide and Renal Stress Resistance.
Poyan Mehr A, Parikh SM. Poyan Mehr A, et al. Nephron. 2017;137(4):253-255. doi: 10.1159/000471895. Epub 2017 Jun 8. Nephron. 2017. PMID: 28591759 Free PMC article. Review.
Recent work proposes that renal PGC1alpha directly increases levels of nicotinamide adenine dinucleotide (NAD+), an essential co-factor for energy metabolism that has lately been proposed as an anti-aging factor. This mini-review summarizes recent stud …
Recent work proposes that renal PGC1alpha directly increases levels of nicotinamide adenine dinucleotide (NAD+), …
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