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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1939 1
1945 2
1946 7
1947 13
1948 19
1949 21
1950 104
1951 77
1952 149
1953 126
1954 172
1955 156
1956 186
1957 185
1958 185
1959 97
1960 56
1961 66
1962 106
1963 549
1964 765
1965 799
1966 770
1967 887
1968 1012
1969 1080
1970 1094
1971 1155
1972 1292
1973 1092
1974 1018
1975 1163
1976 1071
1977 1003
1978 892
1979 893
1980 998
1981 814
1982 924
1983 851
1984 989
1985 945
1986 923
1987 876
1988 845
1989 950
1990 952
1991 944
1992 972
1993 976
1994 1012
1995 1085
1996 1062
1997 1112
1998 1098
1999 1180
2000 1131
2001 1228
2002 1260
2003 1287
2004 1347
2005 1478
2006 1396
2007 1501
2008 1636
2009 1622
2010 1707
2011 1831
2012 2009
2013 2319
2014 2198
2015 2164
2016 2176
2017 2197
2018 2261
2019 2296
2020 1268
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70,065 results
Results by year
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Page 1
Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration.
Pehar M, Harlan BA, Killoy KM, Vargas MR. Pehar M, et al. Antioxid Redox Signal. 2018 Jun 20;28(18):1652-1668. doi: 10.1089/ars.2017.7145. Epub 2017 Jun 27. Antioxid Redox Signal. 2018. PMID: 28548540 Free PMC article. Review.
SIGNIFICANCE: Nicotinamide adenine dinucleotide (NAD(+)) participates in redox reactions and NAD(+)-dependent signaling processes, which involve the cleavage of NAD(+) coupled to posttranslational modifications of proteins or the producti …
SIGNIFICANCE: Nicotinamide adenine dinucleotide (NAD(+)) participates in redox reactions and NAD(+)-depen …
Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration.
Mukherjee S, Chellappa K, Moffitt A, Ndungu J, Dellinger RW, Davis JG, Agarwal B, Baur JA. Mukherjee S, et al. Hepatology. 2017 Feb;65(2):616-630. doi: 10.1002/hep.28912. Epub 2016 Dec 24. Hepatology. 2017. PMID: 27809334 Free PMC article.
During liver regeneration, the concentration of nicotinamide adenine dinucleotide (NAD) falls, at least in part due to metabolic competition for precursors. To test whether NAD availability restricts the rate of liver regeneration, we supplied …
During liver regeneration, the concentration of nicotinamide adenine dinucleotide (NAD) falls, at least in part …
Nicotinamide adenine dinucleotide and its related precursors for the treatment of Alzheimer's disease.
Braidy N, Grant R, Sachdev PS. Braidy N, et al. Curr Opin Psychiatry. 2018 Mar;31(2):160-166. doi: 10.1097/YCO.0000000000000394. Curr Opin Psychiatry. 2018. PMID: 29232252 Review.
PURPOSE OF REVIEW: The current review discusses the biology and metabolism of the essential pyridine nucleotide nicotinamide adenine dinucleotide (NAD+) in the central nervous system. We also review recent work suggesting important neuroprotective effe …
PURPOSE OF REVIEW: The current review discusses the biology and metabolism of the essential pyridine nucleotide nicotinamide adeni
Nicotinamide adenine dinucleotide emerges as a therapeutic target in aging and ischemic conditions.
Hosseini L, Vafaee MS, Mahmoudi J, Badalzadeh R. Hosseini L, et al. Biogerontology. 2019 Aug;20(4):381-395. doi: 10.1007/s10522-019-09805-6. Epub 2019 Mar 5. Biogerontology. 2019. PMID: 30838484 Review.
Nicotinamide adenine dinucleotide (NAD(+)) has been described as central coenzyme of redox reactions and is a key regulator of stress resistance and longevity. ...The majority of studies have shown that restoring of NAD(+) using supplementation
Nicotinamide adenine dinucleotide (NAD(+)) has been described as central coenzyme of redox reactions and is a ke
Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors.
Lu W, Wang L, Chen L, Hui S, Rabinowitz JD. Lu W, et al. Antioxid Redox Signal. 2018 Jan 20;28(3):167-179. doi: 10.1089/ars.2017.7014. Epub 2017 Jul 19. Antioxid Redox Signal. 2018. PMID: 28497978 Free PMC article.
AIMS: Accurate analysis of dinucleotide redox cofactors nicotinamide adenine dinucleotide phosphate reduced (NADPH), nicotinamide adenine dinucleotide phosphate (NADP(+)), nicotinamide adenine dinucleotide redu …
AIMS: Accurate analysis of dinucleotide redox cofactors nicotinamide adenine dinucleotide phosphate reduced (NAD …
Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes.
Braidy N, Berg J, Clement J, Khorshidi F, Poljak A, Jayasena T, Grant R, Sachdev P. Braidy N, et al. Antioxid Redox Signal. 2019 Jan 10;30(2):251-294. doi: 10.1089/ars.2017.7269. Epub 2018 May 11. Antioxid Redox Signal. 2019. PMID: 29634344 Free PMC article. Review.
Significance: Nicotinamide adenine dinucleotide (NAD(+)) is an essential pyridine nucleotide that serves as an essential cofactor and substrate for a number of critical cellular processes involved in oxidative phosphorylation and ATP production, DNA re …
Significance: Nicotinamide adenine dinucleotide (NAD(+)) is an essential pyridine nucleotide that serves as an e …
PPARγ-Coactivator-1α, Nicotinamide Adenine Dinucleotide and Renal Stress Resistance.
Poyan Mehr A, Parikh SM. Poyan Mehr A, et al. Nephron. 2017;137(4):253-255. doi: 10.1159/000471895. Epub 2017 Jun 8. Nephron. 2017. PMID: 28591759 Free PMC article. Review.
Recent work proposes that renal PGC1α directly increases levels of nicotinamide adenine dinucleotide (NAD+), an essential co-factor for energy metabolism that has lately been proposed as an anti-aging factor. This mini-review summarizes recent studies …
Recent work proposes that renal PGC1α directly increases levels of nicotinamide adenine dinucleotide (NAD+), an …
Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence.
Rajman L, Chwalek K, Sinclair DA. Rajman L, et al. Cell Metab. 2018 Mar 6;27(3):529-547. doi: 10.1016/j.cmet.2018.02.011. Cell Metab. 2018. PMID: 29514064 Free PMC article. Review.
Nicotinamide adenine dinucleotide (NAD), the cell's hydrogen carrier for redox enzymes, is well known for its role in redox reactions. ...By modulating NAD(+)-sensing enzymes, NAD(+) controls hundreds of key processes from energy metaboli
Nicotinamide adenine dinucleotide (NAD), the cell's hydrogen carrier for redox enzymes, is well known for its ro
A novel nicotinamide adenine dinucleotide control strategy for increasing the cell density of Haemophilus parasuis.
Cheng L, Li F, Li S, Lin C, Fu Q, Yin H, Tian F, Qu G, Wu J, Shen Z. Cheng L, et al. Biotechnol Prog. 2019 May;35(3):e2794. doi: 10.1002/btpr.2794. Epub 2019 Mar 9. Biotechnol Prog. 2019. PMID: 30816004
To enhance the production of an inactivated vaccine against H. parasuis, the availability of nicotinamide adenine dinucleotide (NAD) must be carefully controlled to ensure a sufficiently high cell density of H. parasuis. ...By assessing the relationshi …
To enhance the production of an inactivated vaccine against H. parasuis, the availability of nicotinamide adenine dinucleot
Modulating NAD(+) metabolism, from bench to bedside.
Katsyuba E, Auwerx J. Katsyuba E, et al. EMBO J. 2017 Sep 15;36(18):2670-2683. doi: 10.15252/embj.201797135. Epub 2017 Aug 7. EMBO J. 2017. PMID: 28784597 Free PMC article. Review.
Discovered in the beginning of the 20(th) century, nicotinamide adenine dinucleotide (NAD(+)) has evolved from a simple oxidoreductase cofactor to being an essential cosubstrate for a wide range of regulatory proteins that include the sirtuin family of …
Discovered in the beginning of the 20(th) century, nicotinamide adenine dinucleotide (NAD(+)) has evolved from a …
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