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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
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1958 2
1972 1
1973 1
1974 2
1977 1
1978 2
1979 2
1980 1
1982 4
1983 1
1984 1
1986 3
1987 2
1989 4
1990 3
1991 3
1992 4
1993 2
1995 1
1996 2
1997 2
1998 2
2000 1
2001 2
2002 3
2003 3
2004 4
2005 3
2006 3
2007 12
2008 6
2009 8
2010 2
2011 6
2012 5
2013 4
2014 18
2015 20
2016 27
2017 28
2018 58
2019 69
2020 76
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378 results
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Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition.
Bogan KL, Brenner C. Bogan KL, et al. Annu Rev Nutr. 2008;28:115-30. doi: 10.1146/annurev.nutr.28.061807.155443. Annu Rev Nutr. 2008. PMID: 18429699 Review.
The distinct and tissue-specific biosynthetic and/or ligand activities of tryptophan, nicotinic acid, nicotinamide, and the newly identified NAD+ precursor, nicotinamide riboside, reviewed herein, are responsible for vitamin-specific effects and side effects. …
The distinct and tissue-specific biosynthetic and/or ligand activities of tryptophan, nicotinic acid, nicotinamide, and the newly ide …
Nicotinamide riboside, a trace nutrient in foods, is a vitamin B3 with effects on energy metabolism and neuroprotection.
Chi Y, Sauve AA. Chi Y, et al. Curr Opin Clin Nutr Metab Care. 2013 Nov;16(6):657-61. doi: 10.1097/MCO.0b013e32836510c0. Curr Opin Clin Nutr Metab Care. 2013. PMID: 24071780 Review.
Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD), and is a source of Vitamin B3. Evidence indicates that nicotinamide riboside has unique properties as a Vitamin B3. ...The first of these is degradative and produce
Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD), and is a source of Vitamin B3. Evidenc
Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy.
Diguet N, Trammell SAJ, Tannous C, Deloux R, Piquereau J, Mougenot N, Gouge A, Gressette M, Manoury B, Blanc J, Breton M, Decaux JF, Lavery GG, Baczkó I, Zoll J, Garnier A, Li Z, Brenner C, Mericskay M. Diguet N, et al. Circulation. 2018 May 22;137(21):2256-2273. doi: 10.1161/CIRCULATIONAHA.116.026099. Epub 2017 Dec 7. Circulation. 2018. PMID: 29217642 Free PMC article.
RESULTS: We observed a 30% loss in levels of NAD(+) in the murine failing heart of both DCM and transverse aorta constriction mice that was accompanied by a decrease in expression of the nicotinamide phosphoribosyltransferase enzyme that recycles the nicotinamide pr …
RESULTS: We observed a 30% loss in levels of NAD(+) in the murine failing heart of both DCM and transverse aorta constriction mice that was …
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.
Trammell SA, Schmidt MS, Weidemann BJ, Redpath P, Jaksch F, Dellinger RW, Li Z, Abel ED, Migaud ME, Brenner C. Trammell SA, et al. Nat Commun. 2016 Oct 10;7:12948. doi: 10.1038/ncomms12948. Nat Commun. 2016. PMID: 27721479 Free PMC article.
Nicotinamide riboside (NR) is in wide use as an NAD(+) precursor vitamin. Here we determine the time and dose-dependent effects of NR on blood NAD(+) metabolism in humans. We report that human blood NAD(+) can rise as much as 2.7-fold with a single oral dose of NR i
Nicotinamide riboside (NR) is in wide use as an NAD(+) precursor vitamin. Here we determine the time and dose-dependent effect
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.
Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG. Fletcher RS, et al. Mol Metab. 2017 May 29;6(8):819-832. doi: 10.1016/j.molmet.2017.05.011. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752046 Free PMC article.
Dietary supplementation of NAD(+) precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) appear efficacious in elevating muscle NAD(+). ...METHODS: We exploited expression profiling of muscle NAD(+) biosynthetic pathways, single and doubl …
Dietary supplementation of NAD(+) precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) appear ef …
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells.
Ratajczak J, Joffraud M, Trammell SA, Ras R, Canela N, Boutant M, Kulkarni SS, Rodrigues M, Redpath P, Migaud ME, Auwerx J, Yanes O, Brenner C, Cantó C. Ratajczak J, et al. Nat Commun. 2016 Oct 11;7:13103. doi: 10.1038/ncomms13103. Nat Commun. 2016. PMID: 27725675 Free PMC article.
Supplementation with NAD(+) precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), protects against metabolic disease, neurodegenerative disorders and age-related physiological decline in mammals. Here we show that nicotinamid
Supplementation with NAD(+) precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), protec …
Nicotinamide riboside supplementation dysregulates redox and energy metabolism in rats: Implications for exercise performance.
Kourtzidis IA, Dolopikou CF, Tsiftsis AN, Margaritelis NV, Theodorou AA, Zervos IA, Tsantarliotou MP, Veskoukis AS, Vrabas IS, Paschalis V, Kyparos A, Nikolaidis MG. Kourtzidis IA, et al. Exp Physiol. 2018 Oct;103(10):1357-1366. doi: 10.1113/EP086964. Epub 2018 Aug 28. Exp Physiol. 2018. PMID: 30007015 Free article.
Thirty-eight Wistar rats were divided into four groups: control (n=10), exercise (n=9), nicotinamide riboside (n=10) and exercise plus nicotinamide riboside (n=9). Nicotinamide riboside was administered for 21 days [300mg(kg body weight)( …
Thirty-eight Wistar rats were divided into four groups: control (n=10), exercise (n=9), nicotinamide riboside (n=10) and exerc …
Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures.
Elhassan YS, Kluckova K, Fletcher RS, Schmidt MS, Garten A, Doig CL, Cartwright DM, Oakey L, Burley CV, Jenkinson N, Wilson M, Lucas SJE, Akerman I, Seabright A, Lai YC, Tennant DA, Nightingale P, Wallis GA, Manolopoulos KN, Brenner C, Philp A, Lavery GG. Elhassan YS, et al. Cell Rep. 2019 Aug 13;28(7):1717-1728.e6. doi: 10.1016/j.celrep.2019.07.043. Cell Rep. 2019. PMID: 31412242 Free PMC article. Clinical Trial.
Nicotinamide adenine dinucleotide (NAD(+)) is modulated by conditions of metabolic stress and has been reported to decline with aging in preclinical models, but human data are sparse. Nicotinamide riboside (NR) supplementation ameliorates metabolic dysfunctio
Nicotinamide adenine dinucleotide (NAD(+)) is modulated by conditions of metabolic stress and has been reported to decline with aging
Administration of nicotinamide riboside prevents oxidative stress and organ injury in sepsis.
Hong G, Zheng D, Zhang L, Ni R, Wang G, Fan GC, Lu Z, Peng T. Hong G, et al. Free Radic Biol Med. 2018 Aug 1;123:125-137. doi: 10.1016/j.freeradbiomed.2018.05.073. Epub 2018 May 24. Free Radic Biol Med. 2018. PMID: 29803807 Free PMC article.
Nicotinamide riboside (NR) is a precursor of nicotinamide adenine dinucleotide (NAD(+)), which is important in regulating oxidative stress. ...
Nicotinamide riboside (NR) is a precursor of nicotinamide adenine dinucleotide (NAD(+)), which is important in regulati
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Cantó C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J. Cantó C, et al. Cell Metab. 2012 Jun 6;15(6):838-47. doi: 10.1016/j.cmet.2012.04.022. Cell Metab. 2012. PMID: 22682224 Free PMC article.
Here we evaluated whether similar effects could be achieved by increasing the supply of nicotinamide riboside (NR), a recently described natural NAD(+) precursor with the ability to increase NAD(+) levels, Sir2-dependent gene silencing, and replicative life span in …
Here we evaluated whether similar effects could be achieved by increasing the supply of nicotinamide riboside (NR), a recently …
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