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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
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1973 1
1974 2
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1978 2
1979 2
1980 1
1982 4
1983 1
1984 1
1986 3
1987 2
1989 4
1990 3
1991 3
1992 4
1993 2
1995 1
1996 2
1997 2
1998 2
2000 1
2001 2
2002 3
2003 3
2004 4
2005 3
2006 3
2007 12
2008 6
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2010 2
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2017 28
2018 58
2019 69
2020 57
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359 results
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Nicotinamide riboside, a trace nutrient in foods, is a vitamin B3 with effects on energy metabolism and neuroprotection.
Chi Y, Sauve AA. Chi Y, et al. Curr Opin Clin Nutr Metab Care. 2013 Nov;16(6):657-61. doi: 10.1097/MCO.0b013e32836510c0. Curr Opin Clin Nutr Metab Care. 2013. PMID: 24071780 Review.
Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD), and is a source of Vitamin B3. Evidence indicates that nicotinamide riboside has unique properties as a Vitamin B3. ...The first of these is degradative and produce
Nicotinamide riboside is a precursor of nicotinamide adenine dinucleotide (NAD), and is a source of Vitamin B3. Evidenc
Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy.
Diguet N, Trammell SAJ, Tannous C, Deloux R, Piquereau J, Mougenot N, Gouge A, Gressette M, Manoury B, Blanc J, Breton M, Decaux JF, Lavery GG, Baczkó I, Zoll J, Garnier A, Li Z, Brenner C, Mericskay M. Diguet N, et al. Circulation. 2018 May 22;137(21):2256-2273. doi: 10.1161/CIRCULATIONAHA.116.026099. Epub 2017 Dec 7. Circulation. 2018. PMID: 29217642 Free PMC article.
RESULTS: We observed a 30% loss in levels of NAD(+) in the murine failing heart of both DCM and transverse aorta constriction mice that was accompanied by a decrease in expression of the nicotinamide phosphoribosyltransferase enzyme that recycles the nicotinamide pr …
RESULTS: We observed a 30% loss in levels of NAD(+) in the murine failing heart of both DCM and transverse aorta constriction mice that was …
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.
Trammell SA, Schmidt MS, Weidemann BJ, Redpath P, Jaksch F, Dellinger RW, Li Z, Abel ED, Migaud ME, Brenner C. Trammell SA, et al. Nat Commun. 2016 Oct 10;7:12948. doi: 10.1038/ncomms12948. Nat Commun. 2016. PMID: 27721479 Free PMC article.
Nicotinamide riboside (NR) is in wide use as an NAD(+) precursor vitamin. Here we determine the time and dose-dependent effects of NR on blood NAD(+) metabolism in humans. We report that human blood NAD(+) can rise as much as 2.7-fold with a single oral dose of NR i
Nicotinamide riboside (NR) is in wide use as an NAD(+) precursor vitamin. Here we determine the time and dose-dependent effect
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults.
Martens CR, Denman BA, Mazzo MR, Armstrong ML, Reisdorph N, McQueen MB, Chonchol M, Seals DR. Martens CR, et al. Nat Commun. 2018 Mar 29;9(1):1286. doi: 10.1038/s41467-018-03421-7. Nat Commun. 2018. PMID: 29599478 Free PMC article. Clinical Trial.
Nicotinamide adenine dinucleotide (NAD(+)) has emerged as a critical co-substrate for enzymes involved in the beneficial effects of regular calorie restriction on healthspan. ...Here we provide the evidence in a 2 × 6-week randomized, double-blind, placebo-controlled, cros
Nicotinamide adenine dinucleotide (NAD(+)) has emerged as a critical co-substrate for enzymes involved in the beneficial effects of r
Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition.
Bogan KL, Brenner C. Bogan KL, et al. Annu Rev Nutr. 2008;28:115-30. doi: 10.1146/annurev.nutr.28.061807.155443. Annu Rev Nutr. 2008. PMID: 18429699 Review.
The distinct and tissue-specific biosynthetic and/or ligand activities of tryptophan, nicotinic acid, nicotinamide, and the newly identified NAD+ precursor, nicotinamide riboside, reviewed herein, are responsible for vitamin-specific effects and side effects. …
The distinct and tissue-specific biosynthetic and/or ligand activities of tryptophan, nicotinic acid, nicotinamide, and the newly ide …
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells.
Fletcher RS, Ratajczak J, Doig CL, Oakey LA, Callingham R, Da Silva Xavier G, Garten A, Elhassan YS, Redpath P, Migaud ME, Philp A, Brenner C, Canto C, Lavery GG. Fletcher RS, et al. Mol Metab. 2017 May 29;6(8):819-832. doi: 10.1016/j.molmet.2017.05.011. eCollection 2017 Aug. Mol Metab. 2017. PMID: 28752046 Free PMC article.
Dietary supplementation of NAD(+) precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) appear efficacious in elevating muscle NAD(+). ...METHODS: We exploited expression profiling of muscle NAD(+) biosynthetic pathways, single and doubl …
Dietary supplementation of NAD(+) precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) appear ef …
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells.
Ratajczak J, Joffraud M, Trammell SA, Ras R, Canela N, Boutant M, Kulkarni SS, Rodrigues M, Redpath P, Migaud ME, Auwerx J, Yanes O, Brenner C, Cantó C. Ratajczak J, et al. Nat Commun. 2016 Oct 11;7:13103. doi: 10.1038/ncomms13103. Nat Commun. 2016. PMID: 27725675 Free PMC article.
Supplementation with NAD(+) precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), protects against metabolic disease, neurodegenerative disorders and age-related physiological decline in mammals. Here we show that nicotinamid
Supplementation with NAD(+) precursors, such as nicotinamide mononucleotide (NMN) or nicotinamide riboside (NR), protec …
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Cantó C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J. Cantó C, et al. Cell Metab. 2012 Jun 6;15(6):838-47. doi: 10.1016/j.cmet.2012.04.022. Cell Metab. 2012. PMID: 22682224 Free PMC article.
Here we evaluated whether similar effects could be achieved by increasing the supply of nicotinamide riboside (NR), a recently described natural NAD(+) precursor with the ability to increase NAD(+) levels, Sir2-dependent gene silencing, and replicative life span in …
Here we evaluated whether similar effects could be achieved by increasing the supply of nicotinamide riboside (NR), a recently …
Nicotinamide riboside supplementation dysregulates redox and energy metabolism in rats: Implications for exercise performance.
Kourtzidis IA, Dolopikou CF, Tsiftsis AN, Margaritelis NV, Theodorou AA, Zervos IA, Tsantarliotou MP, Veskoukis AS, Vrabas IS, Paschalis V, Kyparos A, Nikolaidis MG. Kourtzidis IA, et al. Exp Physiol. 2018 Oct;103(10):1357-1366. doi: 10.1113/EP086964. Epub 2018 Aug 28. Exp Physiol. 2018. PMID: 30007015
Thirty-eight Wistar rats were divided into four groups: control (n = 10), exercise (n = 9), nicotinamide riboside (n = 10) and exercise plus nicotinamide riboside (n = 9). Nicotinamide riboside was administered for 21 days [300 mg (kg bod …
Thirty-eight Wistar rats were divided into four groups: control (n = 10), exercise (n = 9), nicotinamide riboside (n = 10) and …
The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC and Fly Models of Parkinson's Disease.
Schöndorf DC, Ivanyuk D, Baden P, Sanchez-Martinez A, De Cicco S, Yu C, Giunta I, Schwarz LK, Di Napoli G, Panagiotakopoulou V, Nestel S, Keatinge M, Pruszak J, Bandmann O, Heimrich B, Gasser T, Whitworth AJ, Deleidi M. Schöndorf DC, et al. Cell Rep. 2018 Jun 5;23(10):2976-2988. doi: 10.1016/j.celrep.2018.05.009. Cell Rep. 2018. PMID: 29874584 Free article.
We report that increasing NAD+ via the NAD+ precursor nicotinamide riboside (NR) significantly ameliorates mitochondrial function in patient neurons. Human neurons require nicotinamide phosphoribosyltransferase (NAMPT) to maintain the NAD+ pool and utilize NR …
We report that increasing NAD+ via the NAD+ precursor nicotinamide riboside (NR) significantly ameliorates mitochondrial funct …
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