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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1957 1
1958 2
1972 1
1973 1
1974 2
1977 1
1978 2
1979 2
1980 1
1982 4
1983 1
1984 1
1986 3
1987 2
1989 4
1990 3
1991 3
1992 4
1993 2
1995 1
1996 2
1997 2
1998 2
2000 1
2001 2
2002 3
2003 3
2004 4
2005 3
2006 3
2007 12
2008 6
2009 8
2010 2
2011 6
2012 5
2013 4
2014 18
2015 20
2016 27
2017 28
2018 60
2019 70
2020 85
2021 92
2022 11
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477 results
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Page 1
Nicotinamide Riboside-The Current State of Research and Therapeutic Uses.
Mehmel M, Jovanović N, Spitz U. Mehmel M, et al. Nutrients. 2020 May 31;12(6):1616. doi: 10.3390/nu12061616. Nutrients. 2020. PMID: 32486488 Free PMC article. Review.
Nicotinamide riboside (NR) has recently become one of the most studied nicotinamide adenine dinucleotide (NAD(+)) precursors, due to its numerous potential health benefits mediated via elevated NAD(+) content in the body. ...
Nicotinamide riboside (NR) has recently become one of the most studied nicotinamide adenine dinucleotide (NAD(+)) precu
Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition.
Bogan KL, Brenner C. Bogan KL, et al. Annu Rev Nutr. 2008;28:115-30. doi: 10.1146/annurev.nutr.28.061807.155443. Annu Rev Nutr. 2008. PMID: 18429699 Review.
The distinct and tissue-specific biosynthetic and/or ligand activities of tryptophan, nicotinic acid, nicotinamide, and the newly identified NAD+ precursor, nicotinamide riboside, reviewed herein, are responsible for vitamin-specific effects and side effects. …
The distinct and tissue-specific biosynthetic and/or ligand activities of tryptophan, nicotinic acid, nicotinamide, and the newly ide …
Can nicotinamide riboside protect against cognitive impairment?
Braidy N, Liu Y. Braidy N, et al. Curr Opin Clin Nutr Metab Care. 2020 Nov;23(6):413-420. doi: 10.1097/MCO.0000000000000691. Curr Opin Clin Nutr Metab Care. 2020. PMID: 32925178 Review.
The cognitive benefits of nicotinamide riboside in Alzheimer's disease models may be modulated in part by upregulation of proliferator-activated-gamma coactivator 1alpha-mediated beta-secretase 1(BACE-1) ubiquitination and degradation, preventing Abeta produc …
The cognitive benefits of nicotinamide riboside in Alzheimer's disease models may be modulated in part by upregulation of prol …
Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD(+) Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures.
Elhassan YS, Kluckova K, Fletcher RS, Schmidt MS, Garten A, Doig CL, Cartwright DM, Oakey L, Burley CV, Jenkinson N, Wilson M, Lucas SJE, Akerman I, Seabright A, Lai YC, Tennant DA, Nightingale P, Wallis GA, Manolopoulos KN, Brenner C, Philp A, Lavery GG. Elhassan YS, et al. Cell Rep. 2019 Aug 13;28(7):1717-1728.e6. doi: 10.1016/j.celrep.2019.07.043. Cell Rep. 2019. PMID: 31412242 Free PMC article. Clinical Trial.
Nicotinamide adenine dinucleotide (NAD(+)) is modulated by conditions of metabolic stress and has been reported to decline with aging in preclinical models, but human data are sparse. Nicotinamide riboside (NR) supplementation ameliorates metabolic dysfunctio
Nicotinamide adenine dinucleotide (NAD(+)) is modulated by conditions of metabolic stress and has been reported to decline with aging
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults.
Martens CR, Denman BA, Mazzo MR, Armstrong ML, Reisdorph N, McQueen MB, Chonchol M, Seals DR. Martens CR, et al. Nat Commun. 2018 Mar 29;9(1):1286. doi: 10.1038/s41467-018-03421-7. Nat Commun. 2018. PMID: 29599478 Free PMC article. Clinical Trial.
Nicotinamide adenine dinucleotide (NAD(+)) has emerged as a critical co-substrate for enzymes involved in the beneficial effects of regular calorie restriction on healthspan. ...Here we provide the evidence in a 2 6-week randomized, double-blind, placebo-controlled, crosso
Nicotinamide adenine dinucleotide (NAD(+)) has emerged as a critical co-substrate for enzymes involved in the beneficial effects of r
Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy.
Diguet N, Trammell SAJ, Tannous C, Deloux R, Piquereau J, Mougenot N, Gouge A, Gressette M, Manoury B, Blanc J, Breton M, Decaux JF, Lavery GG, Baczkó I, Zoll J, Garnier A, Li Z, Brenner C, Mericskay M. Diguet N, et al. Circulation. 2018 May 22;137(21):2256-2273. doi: 10.1161/CIRCULATIONAHA.116.026099. Epub 2017 Dec 7. Circulation. 2018. PMID: 29217642 Free PMC article.
RESULTS: We observed a 30% loss in levels of NAD(+) in the murine failing heart of both DCM and transverse aorta constriction mice that was accompanied by a decrease in expression of the nicotinamide phosphoribosyltransferase enzyme that recycles the nicotinamide pr …
RESULTS: We observed a 30% loss in levels of NAD(+) in the murine failing heart of both DCM and transverse aorta constriction mice that was …
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.
Cantó C, Houtkooper RH, Pirinen E, Youn DY, Oosterveer MH, Cen Y, Fernandez-Marcos PJ, Yamamoto H, Andreux PA, Cettour-Rose P, Gademann K, Rinsch C, Schoonjans K, Sauve AA, Auwerx J. Cantó C, et al. Cell Metab. 2012 Jun 6;15(6):838-47. doi: 10.1016/j.cmet.2012.04.022. Cell Metab. 2012. PMID: 22682224 Free PMC article.
Here we evaluated whether similar effects could be achieved by increasing the supply of nicotinamide riboside (NR), a recently described natural NAD(+) precursor with the ability to increase NAD(+) levels, Sir2-dependent gene silencing, and replicative life span in …
Here we evaluated whether similar effects could be achieved by increasing the supply of nicotinamide riboside (NR), a recently …
Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1alpha/mitochondrial biosynthesis pathway.
Wang S, Wan T, Ye M, Qiu Y, Pei L, Jiang R, Pang N, Huang Y, Liang B, Ling W, Lin X, Zhang Z, Yang L. Wang S, et al. Redox Biol. 2018 Jul;17:89-98. doi: 10.1016/j.redox.2018.04.006. Epub 2018 Apr 5. Redox Biol. 2018. PMID: 29679894 Free PMC article.
BACKGROUND: Nicotinamide riboside (NR) is a nicotinamide adenine dinucleotide (NAD(+)) precursor which is present in foods such as milk and beer. ...
BACKGROUND: Nicotinamide riboside (NR) is a nicotinamide adenine dinucleotide (NAD(+)) precursor which is present in fo …
The NAD-Booster Nicotinamide Riboside Potently Stimulates Hematopoiesis through Increased Mitochondrial Clearance.
Vannini N, Campos V, Girotra M, Trachsel V, Rojas-Sutterlin S, Tratwal J, Ragusa S, Stefanidis E, Ryu D, Rainer PY, Nikitin G, Giger S, Li TY, Semilietof A, Oggier A, Yersin Y, Tauzin L, Pirinen E, Cheng WC, Ratajczak J, Canto C, Ehrbar M, Sizzano F, Petrova TV, Vanhecke D, Zhang L, Romero P, Nahimana A, Cherix S, Duchosal MA, Ho PC, Deplancke B, Coukos G, Auwerx J, Lutolf MP, Naveiras O. Vannini N, et al. Cell Stem Cell. 2019 Mar 7;24(3):405-418.e7. doi: 10.1016/j.stem.2019.02.012. Cell Stem Cell. 2019. PMID: 30849366 Free article.
It has been recently shown that increased oxidative phosphorylation, as reflected by increased mitochondrial activity, together with impairment of the mitochondrial stress response, can severely compromise hematopoietic stem cell (HSC) regeneration. Here we show that the NAD(+)-b …
It has been recently shown that increased oxidative phosphorylation, as reflected by increased mitochondrial activity, together with impairm …
Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans.
Remie CME, Roumans KHM, Moonen MPB, Connell NJ, Havekes B, Mevenkamp J, Lindeboom L, de Wit VHW, van de Weijer T, Aarts SABM, Lutgens E, Schomakers BV, Elfrink HL, Zapata-Pérez R, Houtkooper RH, Auwerx J, Hoeks J, Schrauwen-Hinderling VB, Phielix E, Schrauwen P. Remie CME, et al. Am J Clin Nutr. 2020 Aug 1;112(2):413-426. doi: 10.1093/ajcn/nqaa072. Am J Clin Nutr. 2020. PMID: 32320006 Free PMC article. Clinical Trial.
BACKGROUND: Nicotinamide riboside (NR) is an NAD+ precursor that boosts cellular NAD+ concentrations. ...RESULTS: Markers of increased NAD+ synthesis-nicotinic acid adenine dinucleotide and methyl nicotinamide-were elevated in skeletal muscle after NR compare …
BACKGROUND: Nicotinamide riboside (NR) is an NAD+ precursor that boosts cellular NAD+ concentrations. ...RESULTS: Markers of i …
477 results