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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1851 1
1868 1
1872 1
1873 1
1879 1
1882 1
1883 2
1891 1
1898 1
1905 1
1906 1
1907 1
1908 1
1909 3
1913 1
1914 1
1915 1
1917 1
1918 1
1919 2
1920 2
1922 1
1923 3
1924 3
1925 2
1926 1
1927 2
1928 2
1929 1
1934 1
1935 2
1938 1
1939 1
1940 1
1941 1
1942 1
1943 3
1945 12
1946 12
1947 25
1948 27
1949 23
1950 23
1951 30
1952 36
1953 41
1954 44
1955 42
1956 40
1957 35
1958 48
1959 51
1960 66
1961 56
1962 71
1963 112
1964 169
1965 139
1966 153
1967 185
1968 231
1969 219
1970 219
1971 234
1972 282
1973 255
1974 246
1975 213
1976 233
1977 233
1978 215
1979 215
1980 259
1981 224
1982 275
1983 296
1984 332
1985 352
1986 403
1987 424
1988 478
1989 550
1990 521
1991 572
1992 604
1993 640
1994 689
1995 666
1996 665
1997 751
1998 781
1999 888
2000 927
2001 969
2002 1027
2003 1199
2004 1312
2005 1463
2006 1560
2007 1701
2008 1814
2009 1794
2010 1841
2011 1968
2012 2224
2013 2301
2014 2619
2015 2866
2016 2927
2017 2629
2018 2819
2019 3083
2020 3698
2021 3533
2022 3436
2023 3209
2024 3368
2025 297

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63,737 results

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Page 1
Nicotine: From Discovery to Biological Effects.
Sansone L, Milani F, Fabrizi R, Belli M, Cristina M, Zagà V, de Iure A, Cicconi L, Bonassi S, Russo P. Sansone L, et al. Int J Mol Sci. 2023 Sep 26;24(19):14570. doi: 10.3390/ijms241914570. Int J Mol Sci. 2023. PMID: 37834017 Free PMC article. Review.
Nicotine, the primary psychoactive agent in tobacco leaves, has led to the widespread use of tobacco, with over one billion smokers globally. ...Understanding nicotine's complex biological effects is essential for comprehensive research and informed health po
Nicotine, the primary psychoactive agent in tobacco leaves, has led to the widespread use of tobacco, with over one billion smokers g
Nicotine's effect on cognition, a friend or foe?
Wang Q, Du W, Wang H, Geng P, Sun Y, Zhang J, Wang W, Jin X. Wang Q, et al. Prog Neuropsychopharmacol Biol Psychiatry. 2023 Jun 8;124:110723. doi: 10.1016/j.pnpbp.2023.110723. Epub 2023 Feb 1. Prog Neuropsychopharmacol Biol Psychiatry. 2023. PMID: 36736944 Review.
The possible mechanism underlying nicotine's effect is also explored. Finally, nicotine's detrimental effect on cognition is discussed, including in the prenatal and adolescent periods, and high-dose nicotine- and withdrawal-induced memory impai …
The possible mechanism underlying nicotine's effect is also explored. Finally, nicotine's detrimental effect on …
Cognitive Effects of Nicotine: Recent Progress.
Valentine G, Sofuoglu M. Valentine G, et al. Curr Neuropharmacol. 2018;16(4):403-414. doi: 10.2174/1570159X15666171103152136. Curr Neuropharmacol. 2018. PMID: 29110618 Free PMC article. Review.
METHODS: We provide a selective overview of recent advances in understanding nicotine's effects on cognitive function, a discussion of the role of cognitive function in vulnerability to TUD, followed by an overview of the neurobiological mechanisms underlying the co …
METHODS: We provide a selective overview of recent advances in understanding nicotine's effects on cognitive function, a discu …
Nicotinic acetylcholine receptors and nicotine addiction: A brief introduction.
Wittenberg RE, Wolfman SL, De Biasi M, Dani JA. Wittenberg RE, et al. Neuropharmacology. 2020 Oct 15;177:108256. doi: 10.1016/j.neuropharm.2020.108256. Epub 2020 Jul 29. Neuropharmacology. 2020. PMID: 32738308 Free PMC article. Review.
The nAChRs that contain the alpha4 and beta2 subunits, often in combination with the alpha6 subunit, are particularly important for nicotine's ability to increase midbrain dopamine neuron firing rates and phasic burst firing. ...This article is part of the special i …
The nAChRs that contain the alpha4 and beta2 subunits, often in combination with the alpha6 subunit, are particularly important for nicot
E-cigarettes, nicotine, the lung and the brain: multi-level cascading pathophysiology.
Herman M, Tarran R. Herman M, et al. J Physiol. 2020 Nov;598(22):5063-5071. doi: 10.1113/JP278388. Epub 2020 Jul 6. J Physiol. 2020. PMID: 32515030 Free PMC article. Review.
In this review, we have compared and contrasted what is known regarding the effects of nicotine on the lungs vs. the effects of nicotine in the brain in the context of addiction. ...Nicotine's reinforcing properties are primarily mediated by activation …
In this review, we have compared and contrasted what is known regarding the effects of nicotine on the lungs vs. the effects of ni
Nicotine Gateway Effects on Adolescent Substance Use.
Ren M, Lotfipour S. Ren M, et al. West J Emerg Med. 2019 Aug 20;20(5):696-709. doi: 10.5811/westjem.2019.7.41661. West J Emerg Med. 2019. PMID: 31539325 Free PMC article. Review.
A further understanding of the molecular and neurochemical underpinnings of nicotine's gateway effects allows emergency clinicians to advise patients and families and adjust treatment accordingly, which may minimize the use of tobacco, nicotine, and future su …
A further understanding of the molecular and neurochemical underpinnings of nicotine's gateway effects allows emergency clinic …
Molecular Mechanisms Associated with Nicotine Pharmacology and Dependence.
Fowler CD, Turner JR, Imad Damaj M. Fowler CD, et al. Handb Exp Pharmacol. 2020;258:373-393. doi: 10.1007/164_2019_252. Handb Exp Pharmacol. 2020. PMID: 31267166 Free article. Review.
In this chapter, we review the field's current understanding of nicotine's actions in the brain, the neurocircuitry underlying drug dependence, factors that modulate the function of nicotinic acetylcholine receptors, and the role of specific genes in mitigating the …
In this chapter, we review the field's current understanding of nicotine's actions in the brain, the neurocircuitry underlying …
Anhedonia in Nicotine Dependence.
Gilbert DG, Stone BM. Gilbert DG, et al. Curr Top Behav Neurosci. 2022;58:167-184. doi: 10.1007/7854_2022_320. Curr Top Behav Neurosci. 2022. PMID: 35507287 Review.
A report by the national advisory mental health council workgroup on changes to the research domain criteria matrix, 2018) and the Situation x Trait Affective Response (STAR) model of nicotine's effects and nicotine dependence (Gilbert, Smoking individual dif …
A report by the national advisory mental health council workgroup on changes to the research domain criteria matrix, 2018) and the Situation …
Nicotine Effects, Body Weight Concerns and Smoking: A Literature Review.
Cepeda-Benito A. Cepeda-Benito A. Curr Pharm Des. 2020;26(20):2316-2326. doi: 10.2174/1381612826666200401083040. Curr Pharm Des. 2020. PMID: 32233995 Review.
The present review contextualizes the role of nicotine and smoking sensory stimulation on maintaining smoking, describes nicotine's effects on feeding behavior and body weight, and explores the impact of smoking outcome expectancies, including the belief that …
The present review contextualizes the role of nicotine and smoking sensory stimulation on maintaining smoking, describes nicotine
Translational Research in Nicotine Addiction.
Fisher ML, Pauly JR, Froeliger B, Turner JR. Fisher ML, et al. Cold Spring Harb Perspect Med. 2021 Jun 1;11(6):a039776. doi: 10.1101/cshperspect.a039776. Cold Spring Harb Perspect Med. 2021. PMID: 32513669 Free PMC article. Review.
Therefore, the primary goal of preclinical research has been to further the understanding of the neural substrates and genetic influences involved in nicotine's effects and reassess potential drug targets. Pronounced advances have been made by investing in new trans …
Therefore, the primary goal of preclinical research has been to further the understanding of the neural substrates and genetic influences in …
63,737 results
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