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Testing nicotine gum for ulcerative colitis patients. Experience with single-patient trials.
Lashner BA, Hanauer SB, Silverstein MD. Lashner BA, et al. Dig Dis Sci. 1990 Jul;35(7):827-32. doi: 10.1007/BF01536795. Dig Dis Sci. 1990. PMID: 2194767 Clinical Trial.
Epidemiologic studies have documented an association between nonsmoking and ulcerative colitis and case reports have demonstrated that symptoms improve with smoking and worsen with removal of a nicotine source. ...We conclude that a randomized trial for an in …
Epidemiologic studies have documented an association between nonsmoking and ulcerative colitis and case reports have demonstra …
Colonic motility in chronic ulcerative proctosigmoiditis and the effects of nicotine on colonic motility in patients and healthy subjects.
Coulie B, Camilleri M, Bharucha AE, Sandborn WJ, Burton D. Coulie B, et al. Aliment Pharmacol Ther. 2001 May;15(5):653-63. doi: 10.1046/j.1365-2036.2001.00959.x. Aliment Pharmacol Ther. 2001. PMID: 11328259 Clinical Trial.
BACKGROUND: Nicotine decreases diarrhoea and pain in ulcerative colitis without reducing inflammation. ...This dose also accelerated colonic transit. Low-dose nicotine (mimicking a transdermal nicotine patch) reduced colonic compliance in …
BACKGROUND: Nicotine decreases diarrhoea and pain in ulcerative colitis without reducing inflammation. ...This dose als …
Low-dose smoking resumption in ex-smokers with refractory ulcerative colitis.
Calabrese E, Yanai H, Shuster D, Rubin DT, Hanauer SB. Calabrese E, et al. J Crohns Colitis. 2012 Aug;6(7):756-62. doi: 10.1016/j.crohns.2011.12.010. Epub 2012 Jan 15. J Crohns Colitis. 2012. PMID: 22398093
BACKGROUND AND AIM: Ulcerative colitis (UC) is primarily a disease of non-smokers. Ex-smokers may have a more refractory disease course and anecdotal evidence in non-controlled clinical trials have suggested that smoking resumption, or the administration of nicot …
BACKGROUND AND AIM: Ulcerative colitis (UC) is primarily a disease of non-smokers. Ex-smokers may have a more refractory disea …
{alpha}7-nAChR-mediated suppression of hyperexcitability of colonic dorsal root ganglia neurons in experimental colitis.
Abdrakhmanova GR, AlSharari S, Kang M, Damaj MI, Akbarali HI. Abdrakhmanova GR, et al. Am J Physiol Gastrointest Liver Physiol. 2010 Sep;299(3):G761-8. doi: 10.1152/ajpgi.00175.2010. Epub 2010 Jul 1. Am J Physiol Gastrointest Liver Physiol. 2010. PMID: 20595621 Free PMC article.
Controlled clinical trials of nicotine transdermal patch for treatment of ulcerative colitis have been shown to improve histological and global clinical scores of colitis. ...Nicotine gradually reduced regenerative multiple-spike action p …
Controlled clinical trials of nicotine transdermal patch for treatment of ulcerative colitis have been shown to …
In-vivo effect of nicotine on cytokine production by human non-adherent mononuclear cells.
Madretsma S, Wolters LM, van Dijk JP, Tak CJ, Feyerabend C, Wilson JH, Zijlstra FJ. Madretsma S, et al. Eur J Gastroenterol Hepatol. 1996 Oct;8(10):1017-20. doi: 10.1097/00042737-199610000-00016. Eur J Gastroenterol Hepatol. 1996. PMID: 8930570
OBJECTIVE: Ulcerative colitis (UC) is predominantly a disease of non-smokers and treatment with transdermal nicotine improves symptoms in UC patients, whereas smoking seems to have a deleterious effect in patients with Crohn's disease (CD). ...Total amount of …
OBJECTIVE: Ulcerative colitis (UC) is predominantly a disease of non-smokers and treatment with transdermal nicotine im …
The effect of mesalamine and nicotine in the treatment of inflammatory bowel disease.
Bonapace CR, Mays DA. Bonapace CR, et al. Ann Pharmacother. 1997 Jul-Aug;31(7-8):907-13. doi: 10.1177/106002809703100719. Ann Pharmacother. 1997. PMID: 9220055 Review.
OBJECTIVE: To characterize the usefulness of mesalamine and nicotine in the treatment of active ulcerative colitis and inactive Crohn's disease. DATA SOURCES: Citations were selected from the MEDLINE database. ...Other studies have not found a dose-response r …
OBJECTIVE: To characterize the usefulness of mesalamine and nicotine in the treatment of active ulcerative colitis and …