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33 results

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Filters applied: Clinical Trial, in the last 5 years. Clear all
Page 1
Nigella sativa powder for helicobacter pylori infected patients: a randomized, double-blinded, placebo-controlled clinical trial.
Yousefnejad H, Mohammadi F, Alizadeh-Naini M, Hejazi N. Yousefnejad H, et al. BMC Complement Med Ther. 2023 Apr 17;23(1):123. doi: 10.1186/s12906-023-03955-4. BMC Complement Med Ther. 2023. PMID: 37069587 Free PMC article. Clinical Trial.
OBJECTIVE: This double-blind, placebo-controlled, clinical trial was conducted to define the effects of Nigella sativa (N. Sativa) powder plus conventional medical treatment of Helicobacter pylori (H. pylori) on serum ghrelin level and appetite in H. pylori-i …
OBJECTIVE: This double-blind, placebo-controlled, clinical trial was conducted to define the effects of Nigella sativa (N. …
Nigella sativa Seeds Ease Severity of Premenstrual Syndrome in Women: A Randomized, Double-Blinded, Placebo-Controlled Study.
Afrin F, Neela MM, Islam A, Islam MR, Hossain MM. Afrin F, et al. Biomed Res Int. 2025 Nov 19;2025:9811666. doi: 10.1155/bmri/9811666. eCollection 2025. Biomed Res Int. 2025. PMID: 41267796 Free PMC article. Clinical Trial.
Lower estrogen levels during the premenstrual phase may contribute to mood swings, anxiety, and fatigue. Nigella sativa (NS) has been examined as a potential alternative therapeutic approach for various diseases. ...
Lower estrogen levels during the premenstrual phase may contribute to mood swings, anxiety, and fatigue. Nigella sativa (NS) h …
Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.
El-Afify D, El Amrousy D. El-Afify D, et al. Paediatr Drugs. 2025 Jul;27(4):481-489. doi: 10.1007/s40272-025-00687-5. Epub 2025 Mar 6. Paediatr Drugs. 2025. PMID: 40048139 Free PMC article. Clinical Trial.
BACKGROUND AND OBJECTIVE: Nigella sativa is a widely used medicinal plant with several potential therapeutic uses. This study aimed to investigate the possible beneficial cardioprotective effect of Nigella sativa in pediatric patients with type 1 diabe …
BACKGROUND AND OBJECTIVE: Nigella sativa is a widely used medicinal plant with several potential therapeutic uses. This study …
Topical Nigella sativa L. product: a new candidate for the management of diabetic peripheral neuropathy.
Khodaie SA, Nikkhah H, Namiranian N, Abotorabi M, Askari M, Khalilzadeh SH, Khatibi Aghda A, Kamalinejad M. Khodaie SA, et al. Inflammopharmacology. 2024 Feb;32(1):551-559. doi: 10.1007/s10787-023-01338-2. Epub 2023 Nov 13. Inflammopharmacology. 2024. PMID: 37957516 Clinical Trial.
In this regard, based on Persian medicinal sources, Nigella sativa (N. sativa) has proved to have beneficial effects on neuropathic pain and neurological disorders. ...CONCLUSION: According to the results of this study, the topical use of N. sativa, co …
In this regard, based on Persian medicinal sources, Nigella sativa (N. sativa) has proved to have beneficial effects on …
Effect of Nigella sativa-L supplementation on glycemia in adolescent polycystic ovarian syndrome: secondary analysis of a randomized controlled trial study.
Mahmoudian A, Ashouri A, Mohammadzadeh F, Rahmani Bilandi R, Dashti S, Bahri N. Mahmoudian A, et al. J Ovarian Res. 2025 Mar 7;18(1):46. doi: 10.1186/s13048-025-01634-1. J Ovarian Res. 2025. PMID: 40055705 Free PMC article. Clinical Trial.
The intervention group received 1000 mg/day of Nigella sativa extract for 16 weeks, while the control group received 10 mg/day of medroxyprogesterone for 10 days per menstrual cycle over the same period. ...Post-intervention, significant interaction effects were obs …
The intervention group received 1000 mg/day of Nigella sativa extract for 16 weeks, while the control group received 10 mg/day …
Effect of Nigella sativa on general health and immune system in young healthy volunteers; a randomized, placebo-controlled, double-blinded clinical trial.
Salem A, Bamosa A, Alam M, Alshuraim S, Alyalak H, Alagga A, Tarabzouni F, Alisa O, Sabit H, Mohsin A, Shaikh M, Farea A, Alshammari T, Obeid O. Salem A, et al. F1000Res. 2023 Oct 18;10:1199. doi: 10.12688/f1000research.73524.2. eCollection 2021. F1000Res. 2023. PMID: 37901256 Free PMC article. Clinical Trial.
Nigella sativa ( N. sativa) is traditionally used as an immune enhancer in different communities. ...This elevation in T cells was lost by increasing the dose of N. sativa to 2g. The rest of the parameters were not changed significantly in all doses. T …
Nigella sativa ( N. sativa) is traditionally used as an immune enhancer in different communities. ...This elevation in …
Nigella sativa for the treatment of COVID-19: An open-label randomized controlled clinical trial.
Koshak AE, Koshak EA, Mobeireek AF, Badawi MA, Wali SO, Malibary HM, Atwah AF, Alhamdan MM, Almalki RA, Madani TA. Koshak AE, et al. Complement Ther Med. 2021 Sep;61:102769. doi: 10.1016/j.ctim.2021.102769. Epub 2021 Aug 15. Complement Ther Med. 2021. PMID: 34407441 Free PMC article. Clinical Trial.
BACKGROUND: Effective treatment for Coronavirus Disease-2019 (COVID-19) is under intensive research. Nigella sativa oil (NSO) is a herbal medicine with antiviral and immunomodulatory activities, and has been recommended for the treatment of COVID-19. ...
BACKGROUND: Effective treatment for Coronavirus Disease-2019 (COVID-19) is under intensive research. Nigella sativa oil (NSO) …
Honey and Nigella sativa against COVID-19 in Pakistan (HNS-COVID-PK): A multicenter placebo-controlled randomized clinical trial.
Ashraf S, Ashraf S, Ashraf M, Imran MA, Kalsoom L, Siddiqui UN, Farooq I, Akmal R, Akram MK, Ashraf S, Ghufran M, Majeed N, Habib Z, Rafique S, -Abdin ZU, Arshad S, Shahab MS, Ahmad S, Zheng H, Mirza AR, Zulfiqar S, Anwar MI, Humayun A, Mahmud T, Saboor QA, Ahmad A, Ashraf M, Izhar M; DOCTORS LOUNGE consortium. Ashraf S, et al. Phytother Res. 2023 Feb;37(2):627-644. doi: 10.1002/ptr.7640. Epub 2022 Nov 24. Phytother Res. 2023. PMID: 36420866 Clinical Trial.
Until now, no specific and effective treatment exists for coronavirus disease 2019 (COVID-19). Since honey and Nigella sativa (HNS) have established antiviral, antibacterial, antiinflammatory, antioxidant, and immunomodulatory properties, we tested their efficacy fo …
Until now, no specific and effective treatment exists for coronavirus disease 2019 (COVID-19). Since honey and Nigella sativa …
The effect of Nigella Sativa emulgel on episiotomy wound healing and pain intensity in primiparous women: A triple-blind randomized controlled trial.
Maghalian M, Alizadeh A, Raphi F, Islambulchilar Z, Khodaie L, Nabighadim M, Taghavi S, Mirghafourvand M. Maghalian M, et al. PLoS One. 2025 Jun 4;20(6):e0325112. doi: 10.1371/journal.pone.0325112. eCollection 2025. PLoS One. 2025. PMID: 40465634 Free PMC article. Clinical Trial.
This study aimed to evaluate the efficacy of Nigella sativa emulgel on episiotomy wound healing and pain intensity in primiparous women. ...No adverse effects were reported, and satisfaction was higher in the Nigella sativa group (86.5% vs. 56.7%; p = …
This study aimed to evaluate the efficacy of Nigella sativa emulgel on episiotomy wound healing and pain intensity in primipar …
Effect of Nigella sativa seed extract on estradiol, FSH levels, and vaginal maturity index in menopausal women: A randomized controlled trial.
Sukatendel K, Hasibuan RH, Siregar MF, Faradina D, Edianto D, Lintang LS, Rusda M, Inriani V. Sukatendel K, et al. Narra J. 2025 Apr;5(1):e1399. doi: 10.52225/narra.v5i1.1399. Epub 2025 Feb 17. Narra J. 2025. PMID: 40352190 Free PMC article. Clinical Trial.
Nigella sativa seed extract has been shown to have a significant effect on endometrial thickness and vaginal cytology in ovariectomized animal models, suggesting potential benefits for managing menopausal symptoms. ...The study used Shad Nigella Plus, an Indo …
Nigella sativa seed extract has been shown to have a significant effect on endometrial thickness and vaginal cytology in ovari …
33 results