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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 2
1984 3
1987 1
1988 3
1989 2
1990 5
1991 4
1992 6
1993 34
1994 4
1997 2
1998 6
1999 8
2000 4
2001 7
2002 9
2003 8
2004 5
2005 7
2006 3
2007 8
2008 3
2009 5
2010 4
2011 2
2012 5
2013 2
2014 2
2015 3
2016 2
2017 2
2018 2
2019 4
2020 1
2021 2
2022 3
2023 0

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169 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Nimesulide-induced hepatotoxicity: A systematic review and meta-analysis.
Kwon J, Kim S, Yoo H, Lee E. Kwon J, et al. PLoS One. 2019 Jan 24;14(1):e0209264. doi: 10.1371/journal.pone.0209264. eCollection 2019. PLoS One. 2019. PMID: 30677025 Free PMC article.
Studies using spontaneous reporting databases were included to estimate reporting odds ratio (ROR) of hepatotoxicity associated with nimesulide exposure. The association between nimesulide use and hepatotoxicity was estimated using relative risk (RR) and ROR with 95 …
Studies using spontaneous reporting databases were included to estimate reporting odds ratio (ROR) of hepatotoxicity associated with nime
Safety of oral use of nimesulide in children: systematic review of randomized controlled trials.
Gupta P, Sachdev HP. Gupta P, et al. Indian Pediatr. 2003 Jun;40(6):518-31. Indian Pediatr. 2003. PMID: 12824661 Free article. Review.
BACKGROUND: Nimesulide has been widely used to treat fever in children. Due to reports of adverse drug reactions, discontinuation or modification of its use has been suggested. OBJECTIVE: To evaluate the safety of oral use of nimesulide in children. DESIGN: Systemat …
BACKGROUND: Nimesulide has been widely used to treat fever in children. Due to reports of adverse drug reactions, discontinuation or …
Individual NSAIDs and upper gastrointestinal complications: a systematic review and meta-analysis of observational studies (the SOS project).
Castellsague J, Riera-Guardia N, Calingaert B, Varas-Lorenzo C, Fourrier-Reglat A, Nicotra F, Sturkenboom M, Perez-Gutthann S; Safety of Non-Steroidal Anti-Inflammatory Drugs (SOS) Project. Castellsague J, et al. Drug Saf. 2012 Dec 1;35(12):1127-46. doi: 10.2165/11633470-000000000-00000. Drug Saf. 2012. PMID: 23137151 Free PMC article. Review.
RR was less than 2 for aceclofenac, celecoxib (RR 1.45; 95% CI 1.17, 1.81) and ibuprofen (RR 1.84; 95% CI 1.54, 2.20); 2 to less than 4 for rofecoxib (RR 2.32; 95% CI 1.89, 2.86), sulindac (RR 2.89; 95% CI 1.90, 4.42), diclofenac (RR 3.34; 95% CI 2.79, 3.99), meloxicam (RR 3.47; …
RR was less than 2 for aceclofenac, celecoxib (RR 1.45; 95% CI 1.17, 1.81) and ibuprofen (RR 1.84; 95% CI 1.54, 2.20); 2 to less than 4 for …
Preemptive effects of ibuprofen and nimesulide on postoperative pain control after open flap periodontal surgeries: A randomized placebo-controlled split-mouth clinical trial.
Santos BFE, Costa FO, Vasconcelos AMA, Cyrino RM, Cota LOM. Santos BFE, et al. J Periodontol. 2022 Feb;93(2):298-307. doi: 10.1002/JPER.20-0887. Epub 2021 Jun 9. J Periodontol. 2022. PMID: 34031888 Clinical Trial.
The aim of this study was to evaluate and compare the analgesic effects of the preemptive administration of ibuprofen and nimesulide in open flap periodontal surgeries. METHODS: The present randomized controlled clinical trial comprised 40 individuals, divided into two gro …
The aim of this study was to evaluate and compare the analgesic effects of the preemptive administration of ibuprofen and nimesulide
Comparison of the efficacy and safety of non-steroidal anti-inflammatory drugs for patients with primary dysmenorrhea: A network meta-analysis.
Feng X, Wang X. Feng X, et al. Mol Pain. 2018 Jan-Dec;14:1744806918770320. doi: 10.1177/1744806918770320. Epub 2018 Mar 27. Mol Pain. 2018. PMID: 29587566 Free PMC article.
Results Totally, 72 randomized controlled trials of 5723 patients and 13 drugs were included in our study after screening. As for pain relief, all drugs except nimesulide, rofecoxib, and waldecoxib were superior to aspirin (odds ratio with 95% credible intervals, diclofena …
Results Totally, 72 randomized controlled trials of 5723 patients and 13 drugs were included in our study after screening. As for pain relie …
Nimesulide in the treatment of menstrual migraine.
Giacovazzo M, Gallo MF, Guidi V, Rico R, Scaricabarozzi I. Giacovazzo M, et al. Drugs. 1993;46 Suppl 1:140-1. doi: 10.2165/00003495-199300461-00031. Drugs. 1993. PMID: 7506154 Clinical Trial.
In a controlled double-blind clinical trial, 30 patients aged 18 to 45 years, with menstrual migraine, were randomly assigned to 2 parallel treatment groups of 15 patients each. One group received granular nimesulide 100mg 3 times daily and the other group received placebo …
In a controlled double-blind clinical trial, 30 patients aged 18 to 45 years, with menstrual migraine, were randomly assigned to 2 parallel …
Effects of nimesulide on the small intestine mucositis induced by methotrexate in rats.
Arslan A, Ozcicek A, Suleyman B, Coban TA, Cimen FK, Nalkiran HS, Kuzucu M, Altuner D, Cetin N, Suleyman H. Arslan A, et al. Exp Anim. 2016 Nov 1;65(4):329-336. doi: 10.1538/expanim.15-0122. Epub 2016 Jun 21. Exp Anim. 2016. PMID: 27333839 Free PMC article. Clinical Trial.
We aimed to investigate the effect of nimesulide on the small intestine mucositis induced by methotrexate (MTX) in rats. ...Whereas, there was only mild irregularities in the villus structures of the NMTXG. Nimesulide protected the small intestines against damage by …
We aimed to investigate the effect of nimesulide on the small intestine mucositis induced by methotrexate (MTX) in rats. ...Whereas, …
Randomized split-mouth study for evaluating the efficacy of nimesulide and nimesulide + Thiocolchicoside combination following impacted mandibular third molar surgery.
Kasapoglu MB, Cebi AT. Kasapoglu MB, et al. Niger J Clin Pract. 2022 May;25(5):641-646. doi: 10.4103/njcp.njcp_1623_21. Niger J Clin Pract. 2022. PMID: 35593607 Clinical Trial.
The VAS levels of nimesulide + thiocolchicoside at the 6(th), 8(th), 12(th), 24(th), and 48(th) hours and on the 3(rd) and 5(th) days were significantly lower than the nimesulide group. The mouth opening was observed higher in the nimesulide + thiocolchicosid …
The VAS levels of nimesulide + thiocolchicoside at the 6(th), 8(th), 12(th), 24(th), and 48(th) hours and on the 3(rd) and 5(th) days …
Nimesulide in the treatment of postoperative pain: a double-blind, comparative study in patients undergoing arthroscopic knee surgery.
Binning A. Binning A. Clin J Pain. 2007 Sep;23(7):565-70. doi: 10.1097/AJP.0b013e3180e00dff. Clin J Pain. 2007. PMID: 17710005 Clinical Trial.
Furthermore, nimesulide also provided significantly better pain relief than naproxen on this parameter. ...All 3 treatments were well tolerated, with a lower number of patients reporting adverse events in the nimesulide group. Nimesulide recipients reported n …
Furthermore, nimesulide also provided significantly better pain relief than naproxen on this parameter. ...All 3 treatments were well …
Effect of preemptive photobiomodulation associated with nimesulide on the postsurgical outcomes, oxidative stress, and quality of life after third molar surgery: a randomized, split-mouth, controlled clinical trial.
Cetira Filho EL, Silva PGB, Wong DVT, Choquenaira-Quispe C, Cesário FRAS, de Sousa Nogueira G, de Sousa AVC, de Aguiar ASW, da Cruz Fonseca SG, Costa FWG. Cetira Filho EL, et al. Clin Oral Investig. 2022 Dec;26(12):6941-6960. doi: 10.1007/s00784-022-04649-w. Epub 2022 Aug 11. Clin Oral Investig. 2022. PMID: 35948699 Free PMC article. Clinical Trial.
RESULTS: Pain peaks occurred after 6 h (nimesulide-placebo [N-P] group) and 8 h (nimesulide group). In the N-P group, LLLT resulted in significantly lower mean pain scores than the subgroup without LLLT after 4 h (p = 0.009) and 6 h (p = 0.048). ...Nimesulide
RESULTS: Pain peaks occurred after 6 h (nimesulide-placebo [N-P] group) and 8 h (nimesulide group). In the N-P group, LLLT res …
169 results