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Clinical advances in obsessive-compulsive disorder: a position statement by the International College of Obsessive-Compulsive Spectrum Disorders.
Fineberg NA, Hollander E, Pallanti S, Walitza S, Grünblatt E, Dell'Osso BM, Albert U, Geller DA, Brakoulias V, Janardhan Reddy YC, Arumugham SS, Shavitt RG, Drummond L, Grancini B, De Carlo V, Cinosi E, Chamberlain SR, Ioannidis K, Rodriguez CI, Garg K, Castle D, Van Ameringen M, Stein DJ, Carmi L, Zohar J, Menchon JM. Fineberg NA, et al. Int Clin Psychopharmacol. 2020 Jul;35(4):173-193. doi: 10.1097/YIC.0000000000000314. Int Clin Psychopharmacol. 2020. PMID: 32433254 Free PMC article. Review.
In this position statement, developed by The International College of Obsessive-Compulsive Spectrum Disorders, a group of international experts responds to recent developments in the evidence-based management of obsessive-compulsive disorder (OCD). The article presents tho …
In this position statement, developed by The International College of Obsessive-Compulsive Spectrum Disorders, a group of international expe …
Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders.
Writing Committee for the Attention-Deficit/Hyperactivity Disorder; Autism Spectrum Disorder; Bipolar Disorder; Major Depressive Disorder; Obsessive-Compulsive Disorder; and Schizophrenia ENIGMA Working Groups; Patel Y, Parker N, Shin J, Howard D, French L, Thomopoulos SI, Pozzi E, Abe Y, Abé C, Anticevic A, Alda M, Aleman A, Alloza C, Alonso-Lana S, Ameis SH, Anagnostou E, McIntosh AA, Arango C, Arnold PD, Asherson P, Assogna F, Auzias G, Ayesa-Arriola R, Bakker G, Banaj N, Banaschewski T, Bandeira CE, Baranov A, Bargalló N, Bau CHD, Baumeister S, Baune BT, Bellgrove MA, Benedetti F, Bertolino A, Boedhoe PSW, Boks M, Bollettini I, Del Mar Bonnin C, Borgers T, Borgwardt S, Brandeis D, Brennan BP, Bruggemann JM, Bülow R, Busatto GF, Calderoni S, Calhoun VD, Calvo R, Canales-Rodríguez EJ, Cannon DM, Carr VJ, Cascella N, Cercignani M, Chaim-Avancini TM, Christakou A, Coghill D, Conzelmann A, Crespo-Facorro B, Cubillo AI, Cullen KR, Cupertino RB, Daly E, Dannlowski U, Davey CG, Denys D, Deruelle C, Di Giorgio A, Dickie EW, Dima D, Dohm K, Ehrlich S, Ely BA, Erwin-Grabner T, Ethofer T, Fair DA, Fallgatter AJ, Faraone SV, Fatjó-Vilas M, Fedor JM, Fitzgerald KD, Ford JM, Frodl T, Fu CHY,… See abstract for full author list ➔ Writing Committee for the Attention-Deficit/Hyperactivity Disorder, et al. JAMA Psychiatry. 2021 Jan 1;78(1):47-63. doi: 10.1001/jamapsychiatry.2020.2694. JAMA Psychiatry. 2021. PMID: 32857118 Free PMC article.
The numbers of cases and controls in each of the 6 disorders were as follows: ADHD: 1814 and 1602; ASD: 1748 and 1770; BD: 1547 and 3405; MDD: 2658 and 3572; OCD: 2266 and 2007; and schizophrenia: 2688 and 3244. MAIN OUTCOMES AND MEASURES: Interregional profiles of group d …
The numbers of cases and controls in each of the 6 disorders were as follows: ADHD: 1814 and 1602; ASD: 1748 and 1770; BD: 1547 and 3405; MD …
Cutting-edge genetics in obsessive-compulsive disorder.
Saraiva LC, Cappi C, Simpson HB, Stein DJ, Viswanath B, van den Heuvel OA, Reddy YJ, Miguel EC, Shavitt RG. Saraiva LC, et al. Fac Rev. 2020 Dec 23;9:30. doi: 10.12703/r/9-30. eCollection 2020. Fac Rev. 2020. PMID: 33659962 Free PMC article. Review.
Findings from this work underscore the notion that the genetic architecture of OCD is highly complex and shared with other neuropsychiatric disorders. ...Studies to date revealed that OCD is not a simple homogeneous entity, but rather that the underlying biological …
Findings from this work underscore the notion that the genetic architecture of OCD is highly complex and shared with other neuropsych …
The role of personality disorders in obsessive-compulsive disorder.
Thamby A, Khanna S. Thamby A, et al. Indian J Psychiatry. 2019 Jan;61(Suppl 1):S114-S118. doi: 10.4103/psychiatry.IndianJPsychiatry_526_18. Indian J Psychiatry. 2019. PMID: 30745684 Free PMC article. Review.
Personality disorders are a common comorbidity in obsessive-compulsive disorder (OCD). The effect of comorbidity on the symptom presentation, course, and treatment outcome of OCD is being discussed here. ...Further research is needed to determine treatment strategie …
Personality disorders are a common comorbidity in obsessive-compulsive disorder (OCD). The effect of comorbidity on the symptom prese …
Cell cycle abnormality is a cellular phenotype in OCD.
Manjappa P, Balachander S, Naaz S, Nadella RK, Shukla T, Paul P, Purushottam M, Janardhan Reddy YC, Jain S, Viswanath B, Sud R. Manjappa P, et al. Asian J Psychiatr. 2021 May;59:102637. doi: 10.1016/j.ajp.2021.102637. Epub 2021 Mar 27. Asian J Psychiatr. 2021. PMID: 33836319
In this study, we therefore aimed to explore cell cycle in OCD. To the best of our knowledge, this is the first study to investigate these effects in OCD. We also evaluated the effect of in vitro fluoxetine, commonly used serotonin reuptake inhibitor (SRI) in OCD …
In this study, we therefore aimed to explore cell cycle in OCD. To the best of our knowledge, this is the first study to investigate …
Toward a neurocircuit-based taxonomy to guide treatment of obsessive-compulsive disorder.
Shephard E, Stern ER, van den Heuvel OA, Costa DLC, Batistuzzo MC, Godoy PBG, Lopes AC, Brunoni AR, Hoexter MQ, Shavitt RG, Reddy YCJ, Lochner C, Stein DJ, Simpson HB, Miguel EC. Shephard E, et al. Mol Psychiatry. 2021 Sep;26(9):4583-4604. doi: 10.1038/s41380-020-01007-8. Epub 2021 Jan 7. Mol Psychiatry. 2021. PMID: 33414496 Free PMC article. Review.
To address this challenge, in this review we propose a heuristic neurocircuit-based taxonomy to guide the treatment of obsessive-compulsive disorder (OCD). We do this by integrating information from several sources. First, we provide case vignettes in which patients with …
To address this challenge, in this review we propose a heuristic neurocircuit-based taxonomy to guide the treatment of obsessive-compulsive …
Obsessive compulsive-disorder and reproductive life events.
Paul I, Saraf G, Chandra PS, Reddy YCJ. Paul I, et al. Asian J Psychiatr. 2020 Aug;52:102124. doi: 10.1016/j.ajp.2020.102124. Epub 2020 Apr 29. Asian J Psychiatr. 2020. PMID: 32361207
We explored the association between reproductive life events and the onset or exacerbation of obsessive-compulsive disorder (OCD) among women in comparison with men with OCD. We chose men because there is some evidence of increased occurrence of OCD in expect …
We explored the association between reproductive life events and the onset or exacerbation of obsessive-compulsive disorder (OCD) amo …
The thalamus and its subnuclei-a gateway to obsessive-compulsive disorder.
Weeland CJ, Kasprzak S, de Joode NT, Abe Y, Alonso P, Ameis SH, Anticevic A, Arnold PD, Balachander S, Banaj N, Bargallo N, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Brecke V, Brem S, Cappi C, Cheng Y, Cho KIK, Costa DLC, Dallaspezia S, Denys D, Eng GK, Ferreira S, Feusner JD, Fontaine M, Fouche JP, Grazioplene RG, Gruner P, He M, Hirano Y, Hoexter MQ, Huyser C, Hu H, Jaspers-Fayer F, Kathmann N, Kaufmann C, Kim M, Koch K, Bin Kwak Y, Kwon JS, Lazaro L, Li CR, Lochner C, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Menchón JM, Minnuzi L, Moreira PS, Morgado P, Nakagawa A, Nakamae T, Narayanaswamy JC, Nurmi EL, Ortiz AE, Pariente JC, Piacentini J, Picó-Pérez M, Piras F, Piras F, Pittenger C, Reddy YCJ, Rodriguez-Manrique D, Sakai Y, Shimizu E, Shivakumar V, Simpson HB, Soreni N, Soriano-Mas C, Sousa N, Spalletta G, Stern ER, Stevens MC, Stewart SE, Szeszko PR, Takahashi J, Tanamatis T, Tang J, Thorsen AL, Tolin D, van der Werf YD, van Marle H, van Wingen GA, Vecchio D, Venkatasubramanian G, Walitza S, Wang J, Wang Z, Watanabe A, Wolters LH, Xu X, Yun JY, Zhao Q; ENIGMA OCD Working Group; White T, Thompson PM, Stein DJ, van den Heuvel OA, Vriend C. Weeland CJ, et al. Transl Psychiatry. 2022 Feb 21;12(1):70. doi: 10.1038/s41398-022-01823-2. Transl Psychiatry. 2022. PMID: 35190533 Free PMC article.
Larger thalamic volume has been found in children with obsessive-compulsive disorder (OCD) and children with clinical-level symptoms within the general population. Particular thalamic subregions may drive these differences. The ENIGMA-OCD working group conducted meg …
Larger thalamic volume has been found in children with obsessive-compulsive disorder (OCD) and children with clinical-level symptoms …
111 results