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Nociceptive, neuropathic, or nociplastic low back pain? The low back pain phenotyping (BACPAP) consortium's international and multidisciplinary consensus recommendations.
Nijs J, Kosek E, Chiarotto A, Cook C, Danneels LA, Fernández-de-Las-Peñas C, Hodges PW, Koes B, Louw A, Ostelo R, Scholten-Peeters GGM, Sterling M, Alkassabi O, Alsobayel H, Beales D, Bilika P, Clark JR, De Baets L, Demoulin C, de Zoete RMJ, Elma Ö, Gutke A, Hanafi R, Hotz Boendermaker S, Huysmans E, Kapreli E, Lundberg M, Malfliet A, Meziat Filho N, Reis FJJ, Voogt L, Zimney K, Smeets R, Morlion B, de Vlam K, George SZ. Nijs J, et al. Lancet Rheumatol. 2024 Mar;6(3):e178-e188. doi: 10.1016/S2665-9913(23)00324-7. Epub 2024 Feb 1. Lancet Rheumatol. 2024. PMID: 38310923 Free article. Review.
The potential to classify low back pain as being characterised by dominant nociceptive, neuropathic, or nociplastic mechanisms is a clinically relevant issue. ...The BACPAP consortium's recommendations are also intended to provide direction for future clinica …
The potential to classify low back pain as being characterised by dominant nociceptive, neuropathic, or nociplastic mec …
Low back pain.
Knezevic NN, Candido KD, Vlaeyen JWS, Van Zundert J, Cohen SP. Knezevic NN, et al. Lancet. 2021 Jul 3;398(10294):78-92. doi: 10.1016/S0140-6736(21)00733-9. Epub 2021 Jun 8. Lancet. 2021. PMID: 34115979 Review.
Low back pain covers a spectrum of different types of pain (eg, nociceptive, neuropathic and nociplastic, or non-specific) that frequently overlap. ...Prevention of low back pain is recognised as a pivotal challenge in high-risk populatio …
Low back pain covers a spectrum of different types of pain (eg, nociceptive, neuropathic and nociplastic, or non …
Nociplastic pain: towards an understanding of prevalent pain conditions.
Fitzcharles MA, Cohen SP, Clauw DJ, Littlejohn G, Usui C, Häuser W. Fitzcharles MA, et al. Lancet. 2021 May 29;397(10289):2098-2110. doi: 10.1016/S0140-6736(21)00392-5. Lancet. 2021. PMID: 34062144 Review.
Nociplastic pain is the semantic term suggested by the international community of pain researchers to describe a third category of pain that is mechanistically distinct from nociceptive pain, which is caused by ongoing inflammation and damage of …
Nociplastic pain is the semantic term suggested by the international community of pain researchers to describe a third …
Personalized assessment and management of non-specific low back pain.
Wirth B, Schweinhardt P. Wirth B, et al. Eur J Pain. 2024 Feb;28(2):181-198. doi: 10.1002/ejp.2190. Epub 2023 Oct 24. Eur J Pain. 2024. PMID: 37874300 Review.
BACKGROUND AND OBJECTIVE: Low back pain (LBP), and in particular non-specific low back pain (NSLBP), which accounts for approximately 90% of LBP, is the leading cause of years lived with disability worldwide. ...Thereby, the assessment of the contribut …
BACKGROUND AND OBJECTIVE: Low back pain (LBP), and in particular non-specific low back pain (NSLBP), which accou …
Nociplastic pain: an introduction.
Roecker CB, Schut SM. Roecker CB, et al. J Can Chiropr Assoc. 2025 Aug;69(2):131-144. J Can Chiropr Assoc. 2025. PMID: 41098639 Free PMC article.
Nociplastic pain is a recently defined concept that highlights altered nociceptive processing within the nervous system. ...Understanding nociplastic pain equips chiropractors to support patients with complex chronic pain through compassionate, …
Nociplastic pain is a recently defined concept that highlights altered nociceptive processing within the nervous system. ...Un …
Reduction of Chronic Primary Low Back Pain by Spinal Manipulative Therapy is Accompanied by Decreases in Segmental Mechanical Hyperalgesia and Pain Catastrophizing: A Randomized Placebo-controlled Dual-blind Mixed Experimental Trial.
Gevers-Montoro C, Romero-Santiago B, Medina-García I, Larranaga-Arzamendi B, Álvarez-Gálovich L, Ortega-De Mues A, Piché M. Gevers-Montoro C, et al. J Pain. 2024 Aug;25(8):104500. doi: 10.1016/j.jpain.2024.02.014. Epub 2024 Feb 16. J Pain. 2024. PMID: 38369221 Free article. Clinical Trial.
Chronic primary low back pain (CPLBP) refers to low back pain that persists over 3 months, that cannot be explained by another chronic condition, and that is associated with emotional distress and disability. ...The primary outcomes were CPLBP intensit …
Chronic primary low back pain (CPLBP) refers to low back pain that persists over 3 months, that cannot be explai …
Neuroinflammatory activation in sensory and motor regions of the cortex is related to sensorimotor function in individuals with low back pain maintained by nociplastic mechanisms: A preliminary proof-of-concept study.
Shraim MA, Massé-Alarie H, Farrell MJ, Cavaleri R, Loggia ML, Hodges PW. Shraim MA, et al. Eur J Pain. 2024 Oct;28(9):1607-1626. doi: 10.1002/ejp.2313. Epub 2024 Jul 15. Eur J Pain. 2024. PMID: 39007713
Sleep, depression, disability and pain questionnaires were administered. RESULTS: Neuroinflammatory activation was greater in the lower back cortical representation of S1/M1 of the nociplastic LBP group than both nociceptive LBP and pain-free groups. . …
Sleep, depression, disability and pain questionnaires were administered. RESULTS: Neuroinflammatory activation was greater in the low …
Functional pain disorders - more than nociplastic pain.
Popkirov S, Enax-Krumova EK, Mainka T, Hoheisel M, Hausteiner-Wiehle C. Popkirov S, et al. NeuroRehabilitation. 2020;47(3):343-353. doi: 10.3233/NRE-208007. NeuroRehabilitation. 2020. PMID: 32986624 Review.
BACKGROUND: Nociplastic pain has been recently introduced as a third mechanistic descriptor of pain arising primarily from alterations of neural processing, in contrast to pain due to tissue damage leading to nociceptor activation (nociceptive) or due …
BACKGROUND: Nociplastic pain has been recently introduced as a third mechanistic descriptor of pain arising primarily f …
Back pain treatment: a new perspective.
Steinmetz A. Steinmetz A. Ther Adv Musculoskelet Dis. 2022 Jul 4;14:1759720X221100293. doi: 10.1177/1759720X221100293. eCollection 2022. Ther Adv Musculoskelet Dis. 2022. PMID: 35814351 Free PMC article. Review.
This article aims to provide new perspectives for the treatment of low back pain (LBP). A narrative literature review highlights the treatment strategies currently anchored in the guidelines as well as the extensive attempts to identify subgroups within the non-spec …
This article aims to provide new perspectives for the treatment of low back pain (LBP). A narrative literature review highligh …
Chronic overlapping pain conditions and nociplastic pain.
Johnston KJA, Signer R, Huckins LM. Johnston KJA, et al. HGG Adv. 2025 Jan 9;6(1):100381. doi: 10.1016/j.xhgg.2024.100381. Epub 2024 Nov 4. HGG Adv. 2025. PMID: 39497418 Free PMC article.
Pain experience in these conditions may better fit with a new mechanistic pain descriptor, nociplastic pain, and nociplastic pain may represent a shared underlying factor among COPCs. ...We found 24 independent single nucleotide polymorph …
Pain experience in these conditions may better fit with a new mechanistic pain descriptor, nociplastic pain, and …
68 results