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2003 3
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163 results

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Maria AT, Jorgensen C, Le Quellec A, Noël D, Guilpain P. Maria AT, et al. Among authors: noel d. Arthritis Rheumatol. 2016 Sep;68(9):2348-50. doi: 10.1002/art.39756. Arthritis Rheumatol. 2016. PMID: 27214595 No abstract available.
Multipotent mesenchymal stromal cells and rheumatoid arthritis: risk or benefit?
Bouffi C, Djouad F, Mathieu M, Noël D, Jorgensen C. Bouffi C, et al. Among authors: noel d. Rheumatology (Oxford). 2009 Oct;48(10):1185-9. doi: 10.1093/rheumatology/kep162. Epub 2009 Jun 26. Rheumatology (Oxford). 2009. PMID: 19561159 Review.
Multipotent mesenchymal stromal cells (MSCs) have raised interest mainly because of cartilage/bone differentiation potential which is now partly eclipsed by their capacity to counteract inflammation and suppress host immune responses as well as to prevent fibrosis. ...They …
Multipotent mesenchymal stromal cells (MSCs) have raised interest mainly because of cartilage/bone differentiation potential which is …
Therapeutic potential in rheumatic diseases of extracellular vesicles derived from mesenchymal stromal cells.
Bertolino GM, Maumus M, Jorgensen C, Noël D. Bertolino GM, et al. Among authors: noel d. Nat Rev Rheumatol. 2023 Nov;19(11):682-694. doi: 10.1038/s41584-023-01010-7. Epub 2023 Sep 4. Nat Rev Rheumatol. 2023. PMID: 37666995 Review.
The incidence of rheumatic diseases such as rheumatoid arthritis and osteoarthritis and injuries to articular cartilage that lead to osteochondral defects is predicted to rise as a result of population ageing and the increase in high-intensity physical activities am …
The incidence of rheumatic diseases such as rheumatoid arthritis and osteoarthritis and injuries to articular cartilage that l …
[Mesenchymal stem cells and regenerative medicine: future perspectives in osteoarthritis].
Maumus M, Pers YM, Ruiz M, Jorgensen C, Noël D. Maumus M, et al. Among authors: noel d. Med Sci (Paris). 2018 Dec;34(12):1092-1099. doi: 10.1051/medsci/2018294. Epub 2019 Jan 9. Med Sci (Paris). 2018. PMID: 30623767 Free article. Review. French.
A therapy based on MSCs can be justified in osteoarthritis (OA) thanks to their differentiation abilities but mostly, to their paracrine and immunosuppressive properties. ...Depending on the mode of administration and behavior after implantation, they can decrease local in …
A therapy based on MSCs can be justified in osteoarthritis (OA) thanks to their differentiation abilities but mostly, to their paracr …
Deregulation and therapeutic potential of microRNAs in arthritic diseases.
Vicente R, Noël D, Pers YM, Apparailly F, Jorgensen C. Vicente R, et al. Among authors: noel d. Nat Rev Rheumatol. 2016 Apr;12(4):211-20. doi: 10.1038/nrrheum.2015.162. Epub 2015 Dec 24. Nat Rev Rheumatol. 2016. PMID: 26698025 Review.
In this context, the main musculoskeletal cell lineages, which are generated from the pool of mesenchymal stromal cells (MSCs), and the immune cells that participate in rheumatic diseases are deregulated. ...The main studies that identify miRNAs as regulators of immune cel …
In this context, the main musculoskeletal cell lineages, which are generated from the pool of mesenchymal stromal cells (MSCs), and t …
Therapeutic application of mesenchymal stem cells in osteoarthritis.
Ruiz M, Cosenza S, Maumus M, Jorgensen C, Noël D. Ruiz M, et al. Among authors: noel d. Expert Opin Biol Ther. 2016;16(1):33-42. doi: 10.1517/14712598.2016.1093108. Epub 2015 Sep 28. Expert Opin Biol Ther. 2016. PMID: 26413975 Review.
INTRODUCTION: Osteoarthritis (OA) is a degenerative disease characterized by cartilage degradation and subchondral bone alterations. This disease represents a global public health problem whose prevalence is rapidly growing with the increasing aging of the population. With …
INTRODUCTION: Osteoarthritis (OA) is a degenerative disease characterized by cartilage degradation and subchondral bone alterations. …
Mesenchymal Stromal Cell-Derived Extracellular Vesicles Regulate the Mitochondrial Metabolism via Transfer of miRNAs.
Loussouarn C, Pers YM, Bony C, Jorgensen C, Noël D. Loussouarn C, et al. Among authors: noel d. Front Immunol. 2021 Mar 16;12:623973. doi: 10.3389/fimmu.2021.623973. eCollection 2021. Front Immunol. 2021. PMID: 33796099 Free PMC article. Review.
Mesenchymal stromal cells (MSCs) are the most commonly tested adult progenitor cells in regenerative medicine. ...
Mesenchymal stromal cells (MSCs) are the most commonly tested adult progenitor cells in regenerative medicine. ...
Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis.
Cosenza S, Ruiz M, Toupet K, Jorgensen C, Noël D. Cosenza S, et al. Among authors: noel d. Sci Rep. 2017 Nov 24;7(1):16214. doi: 10.1038/s41598-017-15376-8. Sci Rep. 2017. PMID: 29176667 Free PMC article.
Mesenchymal stem or stromal cells (MSCs) exert chondroprotective effects in preclinical models of osteoarthritis (OA). ...MPs and Exos were isolated from bone marrow murine BM-MSCs through differential centrifugation. Effect of MPs or Exos was evaluated on OA-like m
Mesenchymal stem or stromal cells (MSCs) exert chondroprotective effects in preclinical models of osteoarthritis (OA). ...MPs
Mesenchymal stem cells for the management of inflammation in osteoarthritis: state of the art and perspectives.
Pers YM, Ruiz M, Noël D, Jorgensen C. Pers YM, et al. Among authors: noel d. Osteoarthritis Cartilage. 2015 Nov;23(11):2027-35. doi: 10.1016/j.joca.2015.07.004. Osteoarthritis Cartilage. 2015. PMID: 26521749 Free article. Review.
Osteoarthritis (OA) is the most common form of degenerative arthritis, mainly characterized by the degradation of articular cartilage and associated with subchondral bone lesions. Novel therapeutic approaches for OA include cell-based therapies that have become thri
Osteoarthritis (OA) is the most common form of degenerative arthritis, mainly characterized by the degradation of articular ca
Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis.
Cosenza S, Toupet K, Maumus M, Luz-Crawford P, Blanc-Brude O, Jorgensen C, Noël D. Cosenza S, et al. Among authors: noel d. Theranostics. 2018 Feb 3;8(5):1399-1410. doi: 10.7150/thno.21072. eCollection 2018. Theranostics. 2018. PMID: 29507629 Free PMC article.
Although MSCs can prevent arthritis, the role of MSCs-derived EVs has never been reported in rheumatoid arthritis. ...Our work is the first demonstration of the therapeutic potential of MSCs-derived EVs in inflammatory arthritis....
Although MSCs can prevent arthritis, the role of MSCs-derived EVs has never been reported in rheumatoid arthritis. ...Our work …
163 results