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Sigma-1 Receptor Activation Suppresses Microglia M1 Polarization via Regulating Endoplasmic Reticulum-Mitochondria Contact and Mitochondrial Functions in Stress-Induced Hypertension Rats.
Ooi K, Hu L, Feng Y, Han C, Ren X, Qian X, Huang H, Chen S, Shi Q, Lin H, Wang J, Zhu D, Wang R, Xia C. Ooi K, et al. Mol Neurobiol. 2021 Dec;58(12):6625-6646. doi: 10.1007/s12035-021-02488-6. Epub 2021 Oct 2. Mol Neurobiol. 2021. PMID: 34601668
Exposure to stress plays a detrimental role in the pathogenesis of hypertension via neuroinflammation pathways. ...Sigma-1 receptor activation suppresses microglia M1 polarization and neuroinflammation via regulating endoplasmic reticulum-mitochondria contact
Exposure to stress plays a detrimental role in the pathogenesis of hypertension via neuroinflammation pathways. ...Sigma-1 rec
Migraine Triggers and Oxidative Stress: A Narrative Review and Synthesis.
Borkum JM. Borkum JM. Headache. 2016 Jan;56(1):12-35. doi: 10.1111/head.12725. Epub 2015 Dec 7. Headache. 2016. PMID: 26639834 Free article. Review.
BACKGROUND: Blau theorized that migraine triggers are exposures that in higher amounts would damage the brain. The recent discovery that the TRPA1 ion channel transduces oxidative stress and triggers neurogenic inflammation suggests that oxidative stress may …
BACKGROUND: Blau theorized that migraine triggers are exposures that in higher amounts would damage the brain. The recent discovery t …
Stress Response and Hearing Loss Differentially Contribute to Dynamic Alterations in Hippocampal Neurogenesis and Microglial Reactivity in Mice Exposed to Acute Noise Exposure.
Li Q, Li H, Yao X, Wang C, Liu H, Xu D, Yang C, Zhuang H, Xiao Y, Liu R, Shen S, Zhou S, Fu C, Wang Y, Teng G, Liu L. Li Q, et al. Front Neurosci. 2021 Dec 8;15:749925. doi: 10.3389/fnins.2021.749925. eCollection 2021. Front Neurosci. 2021. PMID: 34955715 Free PMC article.
Beyond its direct effects on the auditory system, exposure to intense noise has previously been shown to acutely activate the stress response, which has increasingly been linked to both microglial activity and adult hippocampal neurogenesis in recent years. . …
Beyond its direct effects on the auditory system, exposure to intense noise has previously been shown to acutely activate the …
Acoustic Stress Induces Opposite Proliferative/Transformative Effects in Hippocampal Glia.
Cruz-Mendoza F, Luquin S, García-Estrada J, Fernández-Quezada D, Jauregui-Huerta F. Cruz-Mendoza F, et al. Int J Mol Sci. 2023 Mar 14;24(6):5520. doi: 10.3390/ijms24065520. Int J Mol Sci. 2023. PMID: 36982594 Free PMC article.
In this study, we aimed to investigate the impact of acoustic stress on hippocampal proliferation and glial cytoarchitecture in adult male rats, using environmental noise as a stress model. After 21 days of noise exposure, our results showed abn …
In this study, we aimed to investigate the impact of acoustic stress on hippocampal proliferation and glial cytoarchitecture in adult …
Involvement of microglial cells in infrasonic noise-induced stress via upregulated expression of corticotrophin releasing hormone type 1 receptor.
Du F, Yin L, Shi M, Cheng H, Xu X, Liu Z, Zhang G, Wu Z, Feng G, Zhao G. Du F, et al. Neuroscience. 2010 May 19;167(3):909-19. doi: 10.1016/j.neuroscience.2010.02.060. Epub 2010 Mar 4. Neuroscience. 2010. PMID: 20206673
Upregulated expression of corticotrophin releasing hormone (CRH) and its receptor CRH-R1 in the neurons of hypothalamic paraventricular nucleus (PVN) was reported to be responsible for infrasonic noise-induced stress and injuries. Recent studies revealed that CRH-R1 …
Upregulated expression of corticotrophin releasing hormone (CRH) and its receptor CRH-R1 in the neurons of hypothalamic paraventricular nucl …
Ablation of lysozyme M-positive cells prevents aircraft noise-induced vascular damage without improving cerebral side effects.
Frenis K, Helmstädter J, Ruan Y, Schramm E, Kalinovic S, Kröller-Schön S, Bayo Jimenez MT, Hahad O, Oelze M, Jiang S, Wenzel P, Sommer CJ, Frauenknecht KBM, Waisman A, Gericke A, Daiber A, Münzel T, Steven S. Frenis K, et al. Basic Res Cardiol. 2021 Apr 30;116(1):31. doi: 10.1007/s00395-021-00869-5. Basic Res Cardiol. 2021. PMID: 33929610 Free PMC article.
Aircraft noise induces vascular and cerebral inflammation and oxidative stress causing hypertension and cardiovascular/cerebral dysfunction. ...In sum, we show dissociation of cerebral and peripheral inflammatory reactions in response to aircraft noise after …
Aircraft noise induces vascular and cerebral inflammation and oxidative stress causing hypertension and cardiovascular/cerebra …
APP/PS1 Gene-Environment Noise Interaction Aggravates AD-like Neuropathology in Hippocampus Via Activation of the VDAC1 Positive Feedback Loop.
Chi H, Zhai Q, Zhang M, Su D, Cao W, Li W, She X, Yang H, Wang K, Gao X, Ma K, Cui B, Qiu Y. Chi H, et al. Curr Alzheimer Res. 2021 Mar 24. doi: 10.2174/1567205018666210324114153. Online ahead of print. Curr Alzheimer Res. 2021. PMID: 33761858
BACKGROUND: Environmental risk factors, including environmental noise stress, and genetic factors, have been associated with the occurrence and development of Alzheimer's disease (AD). ...CONCLUSION: Chronic noise exposure and APP/PS1 overexpres …
BACKGROUND: Environmental risk factors, including environmental noise stress, and genetic factors, have been associated with t …
Melatonin improves quality and longevity of chronic neural recording.
Golabchi A, Wu B, Li X, Carlisle DL, Kozai TDY, Friedlander RM, Cui XT. Golabchi A, et al. Biomaterials. 2018 Oct;180:225-239. doi: 10.1016/j.biomaterials.2018.07.026. Epub 2018 Jul 17. Biomaterials. 2018. PMID: 30053658 Free PMC article.
MT (30 mg/kg) was administered via daily intraperitoneal injection for acute (3 days before and 14 days post-implantation) and chronic (3 days before and 16 weeks post-implantation) exposures. During the first 4 weeks, both MT groups showed significantly higher single-unit …
MT (30 mg/kg) was administered via daily intraperitoneal injection for acute (3 days before and 14 days post-implantation) and chronic (3 da …