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Cognitive maps and schizophrenia.
Nour MM, Liu Y, El-Gaby M, McCutcheon RA, Dolan RJ. Nour MM, et al. Trends Cogn Sci. 2025 Feb;29(2):184-200. doi: 10.1016/j.tics.2024.09.011. Epub 2024 Nov 19. Trends Cogn Sci. 2025. PMID: 39567329 Free article. Review.
The cognitive mapping hypothesis of schizophrenia extends this enquiry to psychiatry, proposing that diverse symptoms - from delusions to conceptual disorganization - stem from abnormalities in how the brain forms structured representations. ...
The cognitive mapping hypothesis of schizophrenia extends this enquiry to psychiatry, proposing that diverse symptoms - from delusion …
Schizophrenia on YouTube.
Nour MM, Nour MH, Tsatalou OM, Barrera A. Nour MM, et al. Among authors: nour mh. Psychiatr Serv. 2017 Jan 1;68(1):70-74. doi: 10.1176/appi.ps.201500541. Epub 2016 Aug 15. Psychiatr Serv. 2017. PMID: 27524369
OBJECTIVE: YouTube ( www.youtube.com ) is the most popular video-sharing Web site on the Internet and is used by medical students as a source of information regarding mental health conditions, including schizophrenia. The accuracy and educational utility of schizophreni …
OBJECTIVE: YouTube ( www.youtube.com ) is the most popular video-sharing Web site on the Internet and is used by medical students as a sourc …
Schizophrenia, Subjectivity, and Mindreading.
Nour MM, Barrera A. Nour MM, et al. Schizophr Bull. 2015 Nov;41(6):1214-9. doi: 10.1093/schbul/sbv035. Epub 2015 Apr 5. Schizophr Bull. 2015. PMID: 25848120 Free PMC article. Review.
A number of recent articles, many appearing in Schizophrenia Bulletin, signal a renewed interest in phenomenological approaches to our understanding of schizophrenia. ...Our hypothesis, while speculative, is an attempt to marry the phenomenological and neuronal real …
A number of recent articles, many appearing in Schizophrenia Bulletin, signal a renewed interest in phenomenological approaches to ou …
Effect of polygenic risk for schizophrenia on cardiac structure and function: a UK Biobank observational study.
Pillinger T, Osimo EF, de Marvao A, Shah M, Francis C, Huang J, D'Ambrosio E, Firth J, Nour MM, McCutcheon RA, Pardiñas AF, Matthews PM, O'Regan DP, Howes OD. Pillinger T, et al. Among authors: nour mm. Lancet Psychiatry. 2023 Feb;10(2):98-107. doi: 10.1016/S2215-0366(22)00403-5. Epub 2023 Jan 8. Lancet Psychiatry. 2023. PMID: 36632818 Free article.
METHODS: For this observational study, we used data from the UK Biobank and included White British or Irish individuals without diagnosed schizophrenia with variable polygenic risk scores for the condition. To test the association between polygenic risk score for schizo …
METHODS: For this observational study, we used data from the UK Biobank and included White British or Irish individuals without diagnosed …
Psychosis as a disorder of muscarinic signalling: psychopathology and pharmacology.
McCutcheon RA, Weber LAE, Nour MM, Cragg SJ, McGuire PM. McCutcheon RA, et al. Among authors: nour mm. Lancet Psychiatry. 2024 Jul;11(7):554-565. doi: 10.1016/S2215-0366(24)00100-7. Epub 2024 May 22. Lancet Psychiatry. 2024. PMID: 38795721 Review.
Dopaminergic receptor antagonism is a crucial component of all licensed treatments for psychosis, and dopamine dysfunction has been central to pathophysiological models of psychotic symptoms. ...
Dopaminergic receptor antagonism is a crucial component of all licensed treatments for psychosis, and dopamine dysfunction has been c …
The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment.
Ashok AH, Marques TR, Jauhar S, Nour MM, Goodwin GM, Young AH, Howes OD. Ashok AH, et al. Among authors: nour mm. Mol Psychiatry. 2017 May;22(5):666-679. doi: 10.1038/mp.2017.16. Epub 2017 Mar 14. Mol Psychiatry. 2017. PMID: 28289283 Free PMC article. Review.
In bipolar depression imaging studies show increased dopamine transporter levels, but changes in other aspects of dopaminergic function are inconsistent. ...Thus, it can be speculated that a failure of dopamine receptor and transporter homoeostasis might underlie th …
In bipolar depression imaging studies show increased dopamine transporter levels, but changes in other aspects of dopaminergic functi …
Trajectories through semantic spaces in schizophrenia and the relationship to ripple bursts.
Nour MM, McNamee DC, Liu Y, Dolan RJ. Nour MM, et al. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2305290120. doi: 10.1073/pnas.2305290120. Epub 2023 Oct 10. Proc Natl Acad Sci U S A. 2023. PMID: 37816054 Free PMC article.
Schizophrenia is also linked to abnormalities in neural processes that support cognitive map representations, including hippocampal replay and high-frequency ripple oscillations. ...The findings bridge a gap between phenomenological and neurocomputational accounts of sc …
Schizophrenia is also linked to abnormalities in neural processes that support cognitive map representations, including hippocampal r …
A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia.
Jauhar S, Nour MM, Veronese M, Rogdaki M, Bonoldi I, Azis M, Turkheimer F, McGuire P, Young AH, Howes OD. Jauhar S, et al. Among authors: nour mm. JAMA Psychiatry. 2017 Dec 1;74(12):1206-1213. doi: 10.1001/jamapsychiatry.2017.2943. JAMA Psychiatry. 2017. PMID: 29049482 Free PMC article.
IMPORTANCE: The dopamine hypothesis suggests that dopamine abnormalities underlie psychosis, irrespective of diagnosis, implicating dopamine dysregulation in bipolar affective disorder and schizophrenia, in line with the research domain criteria approa …
IMPORTANCE: The dopamine hypothesis suggests that dopamine abnormalities underlie psychosis, irrespective of diagnosis, implic …
Reward processing in schizophrenia and its relation to Mu opioid receptor availability and negative symptoms: A [(11)C]-carfentanil PET and fMRI study.
Shatalina E, Ashok AH, Wall MB, Nour MM, Myers J, Reis Marques T, Rabiner EA, Howes OD. Shatalina E, et al. Among authors: nour mm. Neuroimage Clin. 2023;39:103481. doi: 10.1016/j.nicl.2023.103481. Epub 2023 Jul 24. Neuroimage Clin. 2023. PMID: 37517175 Free PMC article.
However, the contribution of Mu Opioid Receptor (MOR) signalling to the reward processing abnormalities in schizophrenia is unknown. Here, we examined the association between MOR availability and the neural processes underlying reward anticipation in patients with schiz …
However, the contribution of Mu Opioid Receptor (MOR) signalling to the reward processing abnormalities in schizophrenia is unknown. …
43 results