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Table representation of search results timeline featuring number of search results per year.

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1952 1
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1962 6
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1970 6
1971 4
1972 5
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1974 7
1975 31
1976 25
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1978 34
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1992 126
1993 130
1994 174
1995 128
1996 183
1997 180
1998 178
1999 212
2000 201
2001 205
2002 221
2003 227
2004 246
2005 253
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2007 273
2008 270
2009 314
2010 328
2011 285
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2013 292
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9,136 results

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Page 1
Physiology, Nociception.
Armstrong SA, Herr MJ. Armstrong SA, et al. 2023 May 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. 2023 May 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan–. PMID: 31855389 Free Books & Documents.
This article will consider the categories of acute and nociceptive pain together. Acute noxious stimuli (e.g., heat, cold, mechanical force, or chemical stimulation) trigger nociceptors. ...The collapse of the nociceptor following stimulation supports the finding th …
This article will consider the categories of acute and nociceptive pain together. Acute noxious stimuli (e.g., heat, cold, mec …
Nociceptors--noxious stimulus detectors.
Woolf CJ, Ma Q. Woolf CJ, et al. Neuron. 2007 Aug 2;55(3):353-64. doi: 10.1016/j.neuron.2007.07.016. Neuron. 2007. PMID: 17678850 Free article. Review.
This is what nociceptors do--these primary sensory neurons are specialized to detect intense stimuli and represent, therefore, the first line of defense against any potentially threatening or damaging environmental inputs. By sensing noxious stimuli and contr …
This is what nociceptors do--these primary sensory neurons are specialized to detect intense stimuli and represent, therefore, the fi …
Pruriceptors.
Ringkamp M, Meyer R. Ringkamp M, et al. In: Carstens E, Akiyama T, editors. Itch: Mechanisms and Treatment. Boca Raton (FL): CRC Press/Taylor & Francis; 2014. Chapter 9. In: Carstens E, Akiyama T, editors. Itch: Mechanisms and Treatment. Boca Raton (FL): CRC Press/Taylor & Francis; 2014. Chapter 9. PMID: 24830025 Free Books & Documents. Review.
Ablation of dorsal horn neurons expressing the gastrin-releasing peptide receptor leads to pronounced inhibition of scratching behavior in mice without affecting behavior induced by noxious stimuli (Sun et al. 2009). Mice, in which the central transmission of nocice …
Ablation of dorsal horn neurons expressing the gastrin-releasing peptide receptor leads to pronounced inhibition of scratching behavior in m …
Exposure to acute noxious heat evokes a cardiorespiratory shock response in humans.
Eimantas N, Ivanove S, Solianik R, Brazaitis M. Eimantas N, et al. Int J Hyperthermia. 2022;39(1):134-143. doi: 10.1080/02656736.2021.2023225. Int J Hyperthermia. 2022. PMID: 35000494 Free article.
Background: Noxious acute cold stimuli cause cold shock via the sympathetic nervous system. However, no studies have investigated respiratory "heat shock" in response to noxious acute heat stimuli ( 42 C).Methods: In the present study, we examined wh …
Background: Noxious acute cold stimuli cause cold shock via the sympathetic nervous system. However, no studies have investiga …
Onset hyperalgesia and offset analgesia: Transient increases or decreases of noxious thermal stimulus intensity robustly modulate subsequent perceived pain intensity.
Alter BJ, Aung MS, Strigo IA, Fields HL. Alter BJ, et al. PLoS One. 2020 Dec 8;15(12):e0231124. doi: 10.1371/journal.pone.0231124. eCollection 2020. PLoS One. 2020. PMID: 33290407 Free PMC article.
Therefore, we examined whether a given noxious stimulus is experienced as more intense when it is preceded by an increase from a lower temperature. ...Overall, this study demonstrates that the perceptual effect of a noxious thermal stimulus is influenc …
Therefore, we examined whether a given noxious stimulus is experienced as more intense when it is preceded by an increase from …
Defining depth of anesthesia.
Shafer SL, Stanski DR. Shafer SL, et al. Handb Exp Pharmacol. 2008;(182):409-23. doi: 10.1007/978-3-540-74806-9_19. Handb Exp Pharmacol. 2008. PMID: 18175102 Review.
We demonstrate the scientific evidence that profound degrees of hypnosis in the absence of analgesia will not prevent the hemodynamic responses to profoundly noxious stimuli. Also, profound degrees of analgesia do not guarantee unconsciousness. However, the combinat …
We demonstrate the scientific evidence that profound degrees of hypnosis in the absence of analgesia will not prevent the hemodynamic respon …
A capsaicin-receptor homologue with a high threshold for noxious heat.
Caterina MJ, Rosen TA, Tominaga M, Brake AJ, Julius D. Caterina MJ, et al. Nature. 1999 Apr 1;398(6726):436-41. doi: 10.1038/18906. Nature. 1999. PMID: 10201375
The cloned capsaicin receptor, also known as the vanilloid receptor subtype 1 (VR1), is a heat-gated ion channel that has been proposed to mediate responses of small-diameter sensory neurons to moderate (43 degrees C) thermal stimuli. VR1 is also activated by protons, indi …
The cloned capsaicin receptor, also known as the vanilloid receptor subtype 1 (VR1), is a heat-gated ion channel that has been proposed to m …
Noxious stimulation of emesis.
Lang IM. Lang IM. Dig Dis Sci. 1999 Aug;44(8 Suppl):58S-63S. Dig Dis Sci. 1999. PMID: 10490041 Review.
Regardless of the stimulus, the afferent neural pathways mediating emesis from the abdomen may be the same. The noxious stimulus may cause release of serotonin from enterochromaffin cells of the digestive tract, which activates visceral afferents. ...
Regardless of the stimulus, the afferent neural pathways mediating emesis from the abdomen may be the same. The noxious sti …
Multimodal pain assessment improves discrimination between noxious and non-noxious stimuli in infants.
van der Vaart M, Duff E, Raafat N, Rogers R, Hartley C, Slater R. van der Vaart M, et al. Paediatr Neonatal Pain. 2019 Sep 9;1(1):21-30. doi: 10.1002/pne2.12007. eCollection 2019 Sep. Paediatr Neonatal Pain. 2019. PMID: 35546868 Free PMC article.
The aim of this study was to investigate how noxious-evoked changes in facial expression, reflex withdrawal, brain activity, heart rate, and oxygen saturation are related and to examine their accuracy in discriminating between noxious and non-noxious stimu …
The aim of this study was to investigate how noxious-evoked changes in facial expression, reflex withdrawal, brain activity, heart ra …
Nociception in Drosophila Larvae.
Borjon LJ, Mauthner SE, Tracey WD. Borjon LJ, et al. Cold Spring Harb Protoc. 2025 Apr 1;2025(4):pdb.top108172. doi: 10.1101/pdb.top108172. Cold Spring Harb Protoc. 2025. PMID: 39095078 Free PMC article.
Nociception is the sensory modality by which animals sense stimuli associated with injury or potential tissue damage. When Drosophila larvae encounter a noxious thermal, chemical, or mechanical stimulus, they perform a stereotyped rolling behavior. These n …
Nociception is the sensory modality by which animals sense stimuli associated with injury or potential tissue damage. When Drosophila …
9,136 results