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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 3
1976 3
1978 3
1979 3
1981 1
1983 3
1984 1
1985 2
1986 1
1987 1
1988 3
1989 5
1990 6
1991 6
1992 4
1993 9
1994 8
1995 10
1996 5
1997 10
1998 18
1999 13
2000 13
2001 20
2002 20
2003 16
2004 14
2005 17
2006 12
2007 21
2008 20
2009 20
2010 16
2011 18
2012 22
2013 24
2014 17
2015 27
2016 18
2017 17
2018 17
2019 23
2020 25
2021 23
2022 18
2023 19
2024 25
2025 36
2026 30

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610 results

Results by year

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Page 1
Do NSAIDs affect bone healing rate, delay union, or cause non-union: an updated systematic review and meta-analysis.
Chuang PY, Yang TY, Tsai YH, Huang KC. Chuang PY, et al. Front Endocrinol (Lausanne). 2024 Sep 10;15:1428240. doi: 10.3389/fendo.2024.1428240. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 39319252 Free PMC article.
INTRODUCTION: Nonsteroidal anti-inflammatory drugs (NSAIDs) may potentially delay or cause non-union of fractures by inhibiting prostaglandin synthesis. ...Specific keywords included "NSAID," "nonsteroidal anti-inflammatory drug," …
INTRODUCTION: Nonsteroidal anti-inflammatory drugs (NSAIDs) may potentially delay or cause non-union of fracture …
Diagnosis, treatment and prevention of ankle sprains: update of an evidence-based clinical guideline.
Vuurberg G, Hoorntje A, Wink LM, van der Doelen BFW, van den Bekerom MP, Dekker R, van Dijk CN, Krips R, Loogman MCM, Ridderikhof ML, Smithuis FF, Stufkens SAS, Verhagen EALM, de Bie RA, Kerkhoffs GMMJ. Vuurberg G, et al. Br J Sports Med. 2018 Aug;52(15):956. doi: 10.1136/bjsports-2017-098106. Epub 2018 Mar 7. Br J Sports Med. 2018. PMID: 29514819
The previous guideline provided evidence that the severity of ligament damage can be assessed most reliably by delayed physical examination (4-5 days post trauma). After correct diagnosis, it can be stated that even though a short time of immobilisation may be helpful in r …
The previous guideline provided evidence that the severity of ligament damage can be assessed most reliably by delayed physical exami …
NSAIDs and fracture healing.
Geusens P, Emans PJ, de Jong JJ, van den Bergh J. Geusens P, et al. Curr Opin Rheumatol. 2013 Jul;25(4):524-31. doi: 10.1097/BOR.0b013e32836200b8. Curr Opin Rheumatol. 2013. PMID: 23680778 Review.
PURPOSE OF REVIEW: Published data raise concerns about the use of nonselective NSAIDs and selective cyclo-oxygenase (COX)-2 inhibitors as anti-inflammatory or analgesic drugs in patients after a recent fracture or who are undergoing (uncemented) arthroplasty …
PURPOSE OF REVIEW: Published data raise concerns about the use of nonselective NSAIDs and selective cyclo-oxygenase (COX)-2 inhibitor …
Treatment of Non-Infectious Corneal Injury: Review of Diagnostic Agents, Therapeutic Medications, and Future Targets.
Dang DH, Riaz KM, Karamichos D. Dang DH, et al. Drugs. 2022 Feb;82(2):145-167. doi: 10.1007/s40265-021-01660-5. Epub 2022 Jan 13. Drugs. 2022. PMID: 35025078 Free PMC article. Review.
Additional topical analgesic agents may be used judiciously to augment patient comfort to facilitate diagnosis. Steroidal anti-inflammatory agents are frequently used as part of the therapeutic regimen. ...For example, several antibiotics, such as doxy …
Additional topical analgesic agents may be used judiciously to augment patient comfort to facilitate diagnosis. Steroidal anti …
Effect of NSAIDs on Bone Healing Rates: A Meta-analysis.
Wheatley BM, Nappo KE, Christensen DL, Holman AM, Brooks DI, Potter BK. Wheatley BM, et al. J Am Acad Orthop Surg. 2019 Apr 1;27(7):e330-e336. doi: 10.5435/JAAOS-D-17-00727. J Am Acad Orthop Surg. 2019. PMID: 30260913
METHODS: We systematically reviewed the literature reporting the effect of NSAIDs on bone healing. We included studies of pediatric and adult patients NSAID exposure and healing bone. ...CONCLUSION: Analysis of the literature indicates a negative effec …
METHODS: We systematically reviewed the literature reporting the effect of NSAIDs on bone healing. We included studies of pedi …
Mucosal repair and COX-2 inhibition.
Perini RF, Ma L, Wallace JL. Perini RF, et al. Curr Pharm Des. 2003;9(27):2207-11. doi: 10.2174/1381612033454027. Curr Pharm Des. 2003. PMID: 14529401 Review.
Prostaglandins play an important role in ulcer healing. Expression of cyclooxygenase-2 (COX-2) is markedly upregulated around the margins of gastric ulcers and its inhibition leads to a delay of ulcer healing. Several of the growth factors that promote ulcer …
Prostaglandins play an important role in ulcer healing. Expression of cyclooxygenase-2 (COX-2) is markedly upregulated around the mar …
Drugs that delay wound healing.
[No authors listed] [No authors listed] Prescrire Int. 2013 Apr;22(137):94-8. Prescrire Int. 2013. PMID: 23662318
Delayed wound healing can have severe and sometimes life-threatening consequences, including deep-seated infection, prolonged hospitalisation, repeat surgery to join or rejoin the wound edges, and delayed functional recovery of a transplanted or …
Delayed wound healing can have severe and sometimes life-threatening consequences, including deep-seated infection, pro …
"Gastric cytoprotection" is still relevant.
Szabo S. Szabo S. J Gastroenterol Hepatol. 2014 Dec;29 Suppl 4:124-32. doi: 10.1111/jgh.12735. J Gastroenterol Hepatol. 2014. PMID: 25521744 Free article. Review.
Thus, PG and histamine, by increasing VP create a perivascular edema that dilutes and delays toxic agents reaching the subepithelial capillaries. Otherwise, damaging chemicals may induce severe early vascular injury resulting in blood flow stasis, hypoxia, and necro …
Thus, PG and histamine, by increasing VP create a perivascular edema that dilutes and delays toxic agents reaching the subepit …
Best evidence topic report. Do non-steroidal anti-inflammatory drugs cause a delay in fracture healing?
Clarke S, Lecky F. Clarke S, et al. Emerg Med J. 2005 Sep;22(9):652-3. doi: 10.1136/emj.2005.028647. Emerg Med J. 2005. PMID: 16113188 Free PMC article. Review.
A short cut review was carried out to establish whether there is any evidence that non-steroidal anti-inflammatory drugs (NSAIDs) might delay fracture healing. A total of 514 papers were found using the reported search, of which th …
A short cut review was carried out to establish whether there is any evidence that non-steroidal anti-inflammatory …
Prostaglandins and ulcer healing.
Konturek SJ, Konturek PC, Brzozowski T. Konturek SJ, et al. J Physiol Pharmacol. 2005 Sep;56 Suppl 5:5-31. J Physiol Pharmacol. 2005. PMID: 16247187 Review.
COX-1 and COX-inhibitors delay ulcer healing, particularly when both COX isoforms are suppressed such e.g. by indomethacin. Dexamethasone, that decreases the expression of COX-2 and mucosal generation of PGE(2), delays ulcer healing that can be reverse …
COX-1 and COX-inhibitors delay ulcer healing, particularly when both COX isoforms are suppressed such e.g. by indomethacin. De …
610 results