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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 3
1976 3
1978 3
1979 3
1981 1
1983 3
1984 1
1985 2
1986 1
1987 1
1988 3
1989 5
1990 6
1991 6
1992 4
1993 9
1994 8
1995 10
1996 5
1997 10
1998 18
1999 13
2000 13
2001 20
2002 20
2003 16
2004 14
2005 17
2006 12
2007 21
2008 20
2009 20
2010 16
2011 18
2012 22
2013 23
2014 17
2015 26
2016 18
2017 17
2018 17
2019 21
2020 10
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455 results
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Page 1
Effect of NSAIDs on Bone Healing Rates: A Meta-analysis.
Wheatley BM, Nappo KE, Christensen DL, Holman AM, Brooks DI, Potter BK. Wheatley BM, et al. J Am Acad Orthop Surg. 2019 Apr 1;27(7):e330-e336. doi: 10.5435/JAAOS-D-17-00727. J Am Acad Orthop Surg. 2019. PMID: 30260913
METHODS: We systematically reviewed the literature reporting the effect of NSAIDs on bone healing. We included studies of pediatric and adult patients NSAID exposure and healing bone. ...RESULTS: NSAID exposure increased delayed union or …
METHODS: We systematically reviewed the literature reporting the effect of NSAIDs on bone healing. We included studies of pedi …
Diagnosis, treatment and prevention of ankle sprains: update of an evidence-based clinical guideline.
Vuurberg G, Hoorntje A, Wink LM, van der Doelen BFW, van den Bekerom MP, Dekker R, van Dijk CN, Krips R, Loogman MCM, Ridderikhof ML, Smithuis FF, Stufkens SAS, Verhagen EALM, de Bie RA, Kerkhoffs GMMJ. Vuurberg G, et al. Br J Sports Med. 2018 Aug;52(15):956. doi: 10.1136/bjsports-2017-098106. Epub 2018 Mar 7. Br J Sports Med. 2018. PMID: 29514819
The previous guideline provided evidence that the severity of ligament damage can be assessed most reliably by delayed physical examination (4-5 days post trauma). ...Care should be taken with non-steroidal anti-inflammatory drugs (NSAIDs
The previous guideline provided evidence that the severity of ligament damage can be assessed most reliably by delayed physical exami …
Nonsteroidal Anti-Inflammatory Drugs and Bone-Healing: A Systematic Review of Research Quality.
Marquez-Lara A, Hutchinson ID, Nuñez F Jr, Smith TL, Miller AN. Marquez-Lara A, et al. JBJS Rev. 2016 Mar 15;4(3):01874474-201603000-00005. doi: 10.2106/JBJS.RVW.O.00055. JBJS Rev. 2016. PMID: 27500434 Review.
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are often avoided by orthopaedic surgeons because of their possible influence on bone-healing. This belief stems from multiple studies, in particular animal studies, that show delayed bon …
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are often avoided by orthopaedic surgeons because of their po …
Ketorolac for postoperative pain in children.
McNicol ED, Rowe E, Cooper TE. McNicol ED, et al. Cochrane Database Syst Rev. 2018 Jul 7;7(7):CD012294. doi: 10.1002/14651858.CD012294.pub2. Cochrane Database Syst Rev. 2018. PMID: 29981164 Free PMC article. Review.
Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce moderate to severe pain without many of the side effects associated with opioids. However, NSAIDs may cause bleeding, renal and gastrointestinal toxicity, and potentially delay wound
Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce moderate to severe pain without many of the side effects assoc …
Tibia fractures and NSAIDs. Does it make a difference? A multicenter retrospective study.
Fader L, Whitaker J, Lopez M, Vivace B, Parra M, Carlson J, Zamora R. Fader L, et al. Injury. 2018 Dec;49(12):2290-2294. doi: 10.1016/j.injury.2018.09.024. Epub 2018 Sep 18. Injury. 2018. PMID: 30270011 Clinical Trial.
PURPOSE: The purpose of this study was to compare healing time for diaphyseal tibia fractures (OTA/AO 42 A, B, C) treated with intramedullary nailing (IMN) in one geographic cohort using nonsteroidal anti-inflammatory drugs (NSAIDs) for post-operative …
PURPOSE: The purpose of this study was to compare healing time for diaphyseal tibia fractures (OTA/AO 42 A, B, C) treated with intram …
Fracture healing in the elderly: A review.
Foulke BA, Kendal AR, Murray DW, Pandit H. Foulke BA, et al. Maturitas. 2016 Oct;92:49-55. doi: 10.1016/j.maturitas.2016.07.014. Epub 2016 Jul 21. Maturitas. 2016. PMID: 27621238 Review.
Complications during fracture healing, including delayed union and non-union, can arise as a result of a multitude of patient and treatment factors. ...Increasing age does seem to increase the risk of delayed union or non-union. In addition, smo …
Complications during fracture healing, including delayed union and non-union, can arise as a result of a multitude of p …
Analgesics Administered for Pain During Hospitalization Following Lower Extremity Fracture: A Review of the Literature.
Griffioen MA, OʼBrien G. Griffioen MA, et al. J Trauma Nurs. 2018 Nov/Dec;25(6):360-365. doi: 10.1097/JTN.0000000000000402. J Trauma Nurs. 2018. PMID: 30395036 Review.
Effective treatment of acute pain during hospitalization following lower extremity fracture is critical to improve short-term patient outcomes including wound healing, stress response, hospital length of stay, and cost as well as minimizing long-term negative patien …
Effective treatment of acute pain during hospitalization following lower extremity fracture is critical to improve short-term patient outcom …
Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications.
Tarnawski AS, Ahluwalia A. Tarnawski AS, et al. World J Gastroenterol. 2018 Nov 14;24(42):4721-4727. doi: 10.3748/wjg.v24.i42.4721. World J Gastroenterol. 2018. PMID: 30479459 Free PMC article.
This risk is further increased in patients using LDA together with other antiplatelet agents, other nonsteroidal anti-inflammatory agents (NSAIDs) and/or alcohol, or in patients with Helicobacter pylori (H. pylori) infection. ...Aging gastric mu …
This risk is further increased in patients using LDA together with other antiplatelet agents, other nonsteroidal anti-infla
No influence of ibuprofen on bone healing after Colles' fracture - A randomized controlled clinical trial.
Aliuskevicius M, Østgaard SE, Rasmussen S. Aliuskevicius M, et al. Injury. 2019 Jul;50(7):1309-1317. doi: 10.1016/j.injury.2019.06.011. Epub 2019 Jun 5. Injury. 2019. PMID: 31186121 Clinical Trial.
INTRODUCTION: Nonsteroidal anti-inflammatory drugs (NSAIDs) may delay bone healing. This knowledge is mainly derived from retrospective uncontrolled clinical studies and from animal experiments. ...The functional outcomes were the percentage dif …
INTRODUCTION: Nonsteroidal anti-inflammatory drugs (NSAIDs) may delay bone healing. This knowledge is mai …
NSAIDs and fracture healing.
Geusens P, Emans PJ, de Jong JJ, van den Bergh J. Geusens P, et al. Curr Opin Rheumatol. 2013 Jul;25(4):524-31. doi: 10.1097/BOR.0b013e32836200b8. Curr Opin Rheumatol. 2013. PMID: 23680778 Review.
PURPOSE OF REVIEW: Published data raise concerns about the use of nonselective NSAIDs and selective cyclo-oxygenase (COX)-2 inhibitors as anti-inflammatory or analgesic drugs in patients after a recent fracture or who are undergoing (uncemented) arthroplasty …
PURPOSE OF REVIEW: Published data raise concerns about the use of nonselective NSAIDs and selective cyclo-oxygenase (COX)-2 inhibitor …
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