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Page 1
Effect of oat beta-glucan in managing blood pressure: a randomized cross-over pilot trial.
Iman Y, Dandeneau D, Wang H, Mollard R, Whitlock R, Ames N, Malunga L, Tangri N, Mackay D, Netticadan T, Thandapilly SJ. Iman Y, et al. Appl Physiol Nutr Metab. 2025 Jan 1;50:1-9. doi: 10.1139/apnm-2024-0317. Appl Physiol Nutr Metab. 2025. PMID: 41031804 Clinical Trial.
High molecular weight (HMW) beta-glucan, a fibre found in oats, may be responsible for reductions in systolic blood pressure. This pilot trial investigated the efficacy of HMW oat beta-glucan in reducing systolic and diastolic blood pr
High molecular weight (HMW) beta-glucan, a fibre found in oats, may be responsible for reductions in systolic blood pressure. …
Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress in men and women with elevated blood pressure.
Maki KC, Galant R, Samuel P, Tesser J, Witchger MS, Ribaya-Mercado JD, Blumberg JB, Geohas J. Maki KC, et al. Eur J Clin Nutr. 2007 Jun;61(6):786-95. doi: 10.1038/sj.ejcn.1602562. Epub 2006 Dec 6. Eur J Clin Nutr. 2007. PMID: 17151592 Clinical Trial.
OBJECTIVE: To assess the effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate homeostasis and biomarkers of oxidative stress. ...SUBJECTS AND INTERVENTIONS: Ninety-seven men and women with resting systolic blo
OBJECTIVE: To assess the effects of consuming foods containing oat beta-glucan on blood pressure, carbohy …
Cereal beta-glucan and cardiovascular disease risk reduction in overweight and obese populations: a systematic review and meta-analysis of lipid, blood pressure, and anthropometric parameters.
Zheng R, Zhang H, Hua H, Zhang Y, Jin C, Zhou Y, Shi X, Zhu L. Zheng R, et al. Food Funct. 2026 Jan 12;17(1):70-88. doi: 10.1039/d5fo03598h. Food Funct. 2026. PMID: 41362998
We assessed the effects of cereal beta-glucan (CBG) on lipids, blood pressure, and anthropometric parameters in individuals with a body mass index (BMI) 25 kg m(-2). ...Pooled analyses showed that CBG significantly reduced total cholesterol [TC, -0.24 mmol L(-1) (- …
We assessed the effects of cereal beta-glucan (CBG) on lipids, blood pressure, and anthropometric parameters in individuals wi …
Concentrated oat beta-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial.
Queenan KM, Stewart ML, Smith KN, Thomas W, Fulcher RG, Slavin JL. Queenan KM, et al. Nutr J. 2007 Mar 26;6:6. doi: 10.1186/1475-2891-6-6. Nutr J. 2007. PMID: 17386092 Free PMC article. Clinical Trial.
We investigated the physiological effects of a concentrated oat beta-glucan on cardiovascular disease (CVD) endpoints in human subjects. We also compared the fermentability of concentrated oat beta-glucan with inulin and guar gum in a mod …
We investigated the physiological effects of a concentrated oat beta-glucan on cardiovascular disease (CVD) endpoints i …
Effect of oat supplementation interventions on cardiovascular disease risk markers: a systematic review and meta-analysis of randomized controlled trials.
Llanaj E, Dejanovic GM, Valido E, Bano A, Gamba M, Kastrati L, Minder B, Stojic S, Voortman T, Marques-Vidal P, Stoyanov J, Metzger B, Glisic M, Kern H, Muka T. Llanaj E, et al. Eur J Nutr. 2022 Jun;61(4):1749-1778. doi: 10.1007/s00394-021-02763-1. Epub 2022 Jan 3. Eur J Nutr. 2022. PMID: 34977959 Free PMC article.
RCTs comparing an OSI to heterogeneous interventions (e.g., wheat, eggs, rice, etc.), showed lowered levels of glycated haemoglobin, diastolic blood pressure, HDL cholesterol and apolipoprotein B. The majority of included RCTs (81.1%) had some concerns for risk of b …
RCTs comparing an OSI to heterogeneous interventions (e.g., wheat, eggs, rice, etc.), showed lowered levels of glycated haemoglobin, diastol …
An encompassing review of meta-analyses and systematic reviews of the effect of oats on all-cause mortality, cardiovascular risk, diabetes risk, body weight/adiposity and gut health.
Mathews R, Chu Y. Mathews R, et al. Crit Rev Food Sci Nutr. 2025;65(13):2587-2608. doi: 10.1080/10408398.2024.2382352. Epub 2024 Aug 13. Crit Rev Food Sci Nutr. 2025. PMID: 39137936 Review.
The purpose of this review was to critically evaluate the state of the science of oats in relation to all-cause mortality, cardiovascular and diabetes risk and the effects of oats on blood lipids, blood glucose, blood pressure, weight management and gu …
The purpose of this review was to critically evaluate the state of the science of oats in relation to all-cause mortality, cardiovascular an …
Oat Beta-Glucan Alone and in Combination with Hydrochlorothiazide Lowers High Blood Pressure in Male but Not Female Spontaneously Hypertensive Rats.
Raj P, Sayfee K, Yu L, Sabra A, Wijekoon C, Malunga L, Thandapilly SJ, Netticadan T. Raj P, et al. Nutrients. 2023 Jul 18;15(14):3180. doi: 10.3390/nu15143180. Nutrients. 2023. PMID: 37513599 Free PMC article.
Here, we examined the cardiovascular benefits of an oat beta-glucan extract in male and female spontaneously hypertensive rats (SHRs) to unravel its sex-specific roles when used with an anti-hypertensive medication, hydrochlorothiazide. Five-week-old male and …
Here, we examined the cardiovascular benefits of an oat beta-glucan extract in male and female spontaneously hypertensi …
Dietary Supplements Containing Oat Beta-Glucan and/or Green Coffee (Poly)phenols Showed Limited Effect in Modulating Cardiometabolic Risk Biomarkers in Overweight/Obese Patients without a Lifestyle Intervention.
García-Cordero J, Mateos R, González-Rámila S, Seguido MA, Sierra-Cinos JL, Sarriá B, Bravo L. García-Cordero J, et al. Nutrients. 2023 May 8;15(9):2223. doi: 10.3390/nu15092223. Nutrients. 2023. PMID: 37432380 Free PMC article. Clinical Trial.
A randomised, crossover, blind trial was carried out in 29 volunteers who consumed either GCP (300 mg), BG (2.5 g) or GCP/BG (300 mg + 2.5 g) twice a day for 8 weeks. Blood samples were collected, and blood pressure and body composition were measured at the b …
A randomised, crossover, blind trial was carried out in 29 volunteers who consumed either GCP (300 mg), BG (2.5 g) or GCP/BG (300 mg + 2.5 g …