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Craniocervical instability in patients with Ehlers-Danlos syndromes: outcomes analysis following occipito-cervical fusion of published cases.
Mughal ZUN, Malik A. Mughal ZUN, et al. Neurosurg Rev. 2024 Apr 16;47(1):158. doi: 10.1007/s10143-024-02395-z. Neurosurg Rev. 2024. PMID: 38625445
This critique provides a critical analysis of the outcomes following occipito-cervical fusion in patients with Ehlers-Danlos syndromes (EDS) and craniocervical instability. ...Future research efforts should focus on addressing these concerns to optimiz …
This critique provides a critical analysis of the outcomes following occipito-cervical fusion in patients with Ehlers- …
Craniocervical instability in patients with Ehlers-Danlos syndrome: controversies in diagnosis and management.
Mao G, Kopparapu S, Jin Y, Davidar AD, Hersh AM, Weber-Levine C, Theodore N. Mao G, et al. Spine J. 2022 Dec;22(12):1944-1952. doi: 10.1016/j.spinee.2022.08.008. Epub 2022 Aug 24. Spine J. 2022. PMID: 36028216 Review.
Ehlers-Danlos syndrome (EDS) is a rare hereditary condition that can result in ligamentous laxity and hypermobility of the cervical spine. ...Here we comprehensively review the available medical literature to critically appraise the evidence behind various proposed …
Ehlers-Danlos syndrome (EDS) is a rare hereditary condition that can result in ligamentous laxity and hypermobility of the cer …
Neurosurgical management of patients with Ehlers-Danlos syndrome: A descriptive case series.
Rock MB, Zhao DY, Felbaum DR, Sandhu FA. Rock MB, et al. J Craniovertebr Junction Spine. 2023 Jan-Mar;14(1):24-34. doi: 10.4103/jcvjs.jcvjs_127_22. Epub 2023 Mar 13. J Craniovertebr Junction Spine. 2023. PMID: 37213579 Free PMC article.
INTRODUCTION: Ehlers-Danlos syndrome (EDS) is a connective tissue disorder that has been linked to several neurological problems including Chiari malformations, atlantoaxial instability (AAI), craniocervical instability (CCI), and tethered cord syndrome. ...The pati …
INTRODUCTION: Ehlers-Danlos syndrome (EDS) is a connective tissue disorder that has been linked to several neurological proble …
Predicting clinical outcomes using morphometric changes in adults with complex Chiari malformation undergoing occipitocervical fusion with or without ventral decompression: patient series.
Chae JK, Marianayagam NJ, Hussain I, Cruz A, Baaj AA, Härtl R, Greenfield JP. Chae JK, et al. J Neurosurg Case Lessons. 2021 Nov 29;2(22):CASE21364. doi: 10.3171/CASE21364. eCollection 2021 Nov 29. J Neurosurg Case Lessons. 2021. PMID: 36059719 Free PMC article.
BACKGROUND: The authors assessed the connection between clinical outcomes and morphometrics in patients with complex Chiari malformation (CM) who have undergone posterior fossa decompression (PFD) and subsequent occipitocervical fusion (OCF) with or without v …
BACKGROUND: The authors assessed the connection between clinical outcomes and morphometrics in patients with complex Chiari malformat …
Craniocervical Stabilization After Failed Chiari Decompression: A Case Series of a Population with High Prevalence of Ehlers-Danlos Syndrome.
Zhao DY, Rock MB, Sandhu FA. Zhao DY, et al. World Neurosurg. 2022 May;161:e546-e552. doi: 10.1016/j.wneu.2022.02.068. Epub 2022 Feb 19. World Neurosurg. 2022. PMID: 35192974
The purposes of this study were to analyze data from patients who required an occipitocervical fusion (OCF) for the management of CCI after having previously undergone SOC for CM-I to determine if OCF is a safe and effective option and to determine any identifiable …
The purposes of this study were to analyze data from patients who required an occipitocervical fusion (OCF) for the management …
Pediatric occipitocervical fixation: radiographic criteria, surgical technique, and clinical outcomes based on experience of a single surgeon.
Martinez-Del-Campo E, Turner JD, Rangel-Castilla L, Soriano-Baron H, Kalb S, Theodore N. Martinez-Del-Campo E, et al. J Neurosurg Pediatr. 2016 Oct;18(4):452-462. doi: 10.3171/2016.2.PEDS15544. Epub 2016 Jun 10. J Neurosurg Pediatr. 2016. PMID: 27286444
OBJECTIVE If left untreated, occipitocervical (OC) instability may lead to serious neurological injury or death. Open internal fixation is often necessary to protect the neurovascular elements. ...CONCLUSIONS Occipitocervical fixation is safe in children and provide …
OBJECTIVE If left untreated, occipitocervical (OC) instability may lead to serious neurological injury or death. Open internal fixati …
Revision Chiari surgery in adults: surgical evaluation algorithm and outcomes in a continuity-of-care practice.
Nguyen RH, Chae JK, Zappi KE, Luhmann G, Kisselbach A, Cruz A, Greenfield JP. Nguyen RH, et al. Neurosurg Focus. 2024 Aug 1;57(2):E12. doi: 10.3171/2024.5.FOCUS24261. Neurosurg Focus. 2024. PMID: 39316841
The cohort was divided into three groups depending on the type of revision surgery performed: posterior fossa decompression with or without duraplasty (PFD/D group), occipitocervical fusion without ventral decompression (OCF group), and ventral decompression in the …
The cohort was divided into three groups depending on the type of revision surgery performed: posterior fossa decompression with or without …
Chiari type 1 malformations and hypermobility spectrum disorder: clinical outcomes and the importance of the differential diagnosis.
Davidson L, O'Brien PF, Bryant JP, Teti S, Stabingas K, Patel N, Keating G, Phan TN, Rodriguez ET, Donoho DA, Syed HR, Oluigbo C, Myseros JS, Keating RF. Davidson L, et al. Childs Nerv Syst. 2026 Jan 5;42(1):7. doi: 10.1007/s00381-025-06988-x. Childs Nerv Syst. 2026. PMID: 41489686
The authors present a series of patients with G-HSD to demonstrate clinical course and outcomes of operative management and the importance of differentiating symptoms of a Chiari malformation from the often multiple and varied manifestations of G-HSD. ...Ventral decompress …
The authors present a series of patients with G-HSD to demonstrate clinical course and outcomes of operative management and the impor …
Increase in clivo-axial angle is associated with clinical improvement in children undergoing occipitocervical fusion for complex Chiari malformation: patient series.
Marianayagam NJ, Chae JK, Hussain I, Cruz A, Baaj AA, Härtl R, Greenfield JP. Marianayagam NJ, et al. J Neurosurg Case Lessons. 2021 Dec 6;2(23):CASE21433. doi: 10.3171/CASE21433. eCollection 2021 Dec 6. J Neurosurg Case Lessons. 2021. PMID: 36061080 Free PMC article.
BACKGROUND: The authors analyzed the pre- and postoperative morphometric properties of pediatric patients with complex Chiari malformation undergoing occipitocervical fusion (OCF) to assess clinical outcomes and morphometric properties that might influence po …
BACKGROUND: The authors analyzed the pre- and postoperative morphometric properties of pediatric patients with complex Chiari malformation u …
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