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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1995 1
1996 2
1999 4
2000 5
2001 8
2002 4
2003 8
2004 8
2005 12
2006 18
2007 13
2008 17
2009 11
2010 16
2011 15
2012 13
2013 19
2014 17
2015 25
2016 27
2017 19
2018 11
2019 10
2020 4
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Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior.
Patrick RP, Ames BN. Patrick RP, et al. FASEB J. 2015 Jun;29(6):2207-22. doi: 10.1096/fj.14-268342. Epub 2015 Feb 24. FASEB J. 2015. PMID: 25713056 Review.
It has remained unclear why supplementation with omega-3 fatty acids and vitamin D improve cognitive function and behavior in these brain disorders. ...Inadequate levels of vitamin D (∼70% of the population) and omega-3 fatty ac
It has remained unclear why supplementation with omega-3 fatty acids and vitamin D improve cognitive function an …
Omega-3 and Omega-6 Polyunsaturated Fatty Acids in Bipolar Disorder: A Review of Biomarker and Treatment Studies.
Saunders EF, Ramsden CE, Sherazy MS, Gelenberg AJ, Davis JM, Rapoport SI. Saunders EF, et al. J Clin Psychiatry. 2016 Oct;77(10):e1301-e1308. doi: 10.4088/JCP.15r09925. J Clin Psychiatry. 2016. PMID: 27631140 Review.
OBJECTIVE: There is growing evidence that inflammation is an important mediator of pathophysiology in bipolar disorder. The omega-3 (n-3) and omega-6 (n-6) polyunsaturated fatty acid (PUFA) metabolic pathways participate in several inflam …
OBJECTIVE: There is growing evidence that inflammation is an important mediator of pathophysiology in bipolar disorder. The omega
Omega-3 fatty acids and depression: scientific evidence and biological mechanisms.
Grosso G, Galvano F, Marventano S, Malaguarnera M, Bucolo C, Drago F, Caraci F. Grosso G, et al. Oxid Med Cell Longev. 2014;2014:313570. doi: 10.1155/2014/313570. Epub 2014 Mar 18. Oxid Med Cell Longev. 2014. PMID: 24757497 Free PMC article. Review.
The changing of omega-6/omega-3 polyunsaturated fatty acids (PUFA) in the food supply of Western societies occurred over the last 150 years is thought to promote the pathogenesis of many inflammatory-related diseases, including depressive disord …
The changing of omega-6/omega-3 polyunsaturated fatty acids (PUFA) in the food supply of Western societie …
The Psychoneuroimmunological Role of Omega-3 Polyunsaturated Fatty Acids in Major Depressive Disorder and Bipolar Disorder.
Rutkofsky IH, Khan AS, Sahito S, Kumar V. Rutkofsky IH, et al. Adv Mind Body Med. 2017 Summer;31(3):8-16. Adv Mind Body Med. 2017. PMID: 28987035 Review.
Conclusions • The research team concluded that omega-3 fatty acids have therapeutic benefits in the treatment of both MDD and bipolar disorder and are effective as a monotherapy and, particularly, as an adjunct therapy. ...The team also created …
Conclusions • The research team concluded that omega-3 fatty acids have therapeutic benefits in the treatment of …
Omega-3 DHA and EPA for cognition, behavior, and mood: clinical findings and structural-functional synergies with cell membrane phospholipids.
Kidd PM. Kidd PM. Altern Med Rev. 2007 Sep;12(3):207-27. Altern Med Rev. 2007. PMID: 18072818 Free article. Review.
The omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are orthomolecular, conditionally essential nutrients that enhance quality of life and lower the risk of premature death. ...Krill omega-3 phospholipids de …
The omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are orthomolecular, condition …
Cardiometabolic risks and omega-3 index in recent-onset bipolar I disorder.
Wulsin LR, Blom TJ, Durling M, Welge JA, DelBello MP, Adler CM, McNamara RK, Strakowski SM. Wulsin LR, et al. Bipolar Disord. 2018 Nov;20(7):658-665. doi: 10.1111/bdi.12633. Epub 2018 Feb 26. Bipolar Disord. 2018. PMID: 29479787
OBJECTIVES: The aims of the present study were to characterize cardiometabolic risk factors in a cohort of bipolar disorder patients with limited exposure to psychotropic medications, and to evaluate their associations with mood symptoms and omega-3 polyunsat …
OBJECTIVES: The aims of the present study were to characterize cardiometabolic risk factors in a cohort of bipolar disorder patients …
Supplementation with Omega-3 Fatty Acids in Psychiatric Disorders: A Review of Literature Data.
Bozzatello P, Brignolo E, De Grandi E, Bellino S. Bozzatello P, et al. J Clin Med. 2016 Jul 27;5(8):67. doi: 10.3390/jcm5080067. J Clin Med. 2016. PMID: 27472373 Free PMC article. Review.
In patients with attention deficit hyperactivity disorder, small-to-modest effects of omega-3 HUFAs have been found. The most promising results have been reported by studies using high doses of EPA or the association of omega-3 and omega-6 fa
In patients with attention deficit hyperactivity disorder, small-to-modest effects of omega-3 HUFAs have been found. The most …
Trim the fat: the role of omega-3 fatty acids in psychopharmacology.
Nasir M, Bloch MH. Nasir M, et al. Ther Adv Psychopharmacol. 2019 Aug 27;9:2045125319869791. doi: 10.1177/2045125319869791. eCollection 2019. Ther Adv Psychopharmacol. 2019. PMID: 31489174 Free PMC article. Review.
This review examines the evidence for efficacy of omega-3 fatty acids in depressive disorders, bipolar disorder, anxiety disorders, post-traumatic stress disorder (PTSD), and psychosis. ...Evidence of efficacy of omega-3 supplement …
This review examines the evidence for efficacy of omega-3 fatty acids in depressive disorders, bipolar di …
Role of omega-3 fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis of randomized clinical trials.
Grosso G, Pajak A, Marventano S, Castellano S, Galvano F, Bucolo C, Drago F, Caraci F. Grosso G, et al. PLoS One. 2014 May 7;9(5):e96905. doi: 10.1371/journal.pone.0096905. eCollection 2014. PLoS One. 2014. PMID: 24805797 Free PMC article.
BACKGROUND: Despite omega-3 polyunsaturated fatty acids (PUFA) supplementation in depressed patients have been suggested to improve depressive symptomatology, previous findings are not univocal. ...Omega-3 PUFA resulted effective in RCTs …
BACKGROUND: Despite omega-3 polyunsaturated fatty acids (PUFA) supplementation in depressed patients have been s …
Nutrition and Bipolar Depression.
Beyer JL, Payne ME. Beyer JL, et al. Psychiatr Clin North Am. 2016 Mar;39(1):75-86. doi: 10.1016/j.psc.2015.10.003. Epub 2015 Dec 23. Psychiatr Clin North Am. 2016. PMID: 26876319 Review.
As with physical conditions, bipolar disorder is likely to be impacted by diet and nutrition. Patients with bipolar disorder have been noted to have relatively unhealthy diets, which may in part be the reason they also have an elevated risk of metabolic syndrome and …
As with physical conditions, bipolar disorder is likely to be impacted by diet and nutrition. Patients with bipolar disorder h …
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