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Contraceptives in chronic lymphocytic leukemia (CLL): a narrative review.
Al-Shibly R, Qassim N, Alfarsi K, AlShemmari S, Yassin M. Al-Shibly R, et al. Ann Hematol. 2026 Jan 17;105(1):30. doi: 10.1007/s00277-026-06830-7. Ann Hematol. 2026. PMID: 41546716 Free PMC article. Review.
This necessitates the need for tailored contraceptive counseling within a multidisciplinary oncofertility framework (Oktay et al J Clin Oncol 36(19):1994-2001, 2018)....
This necessitates the need for tailored contraceptive counseling within a multidisciplinary oncofertility framework (Oktay et al J Cl …
[Current Status of Oncofertility in Young Patients with Breast Cancer].
Okawa M, Wang B, Takai J, Nakakami A, Niwa Y, Mori R, Terazawa K, Furui T, Matsuhashi N, Futamura M. Okawa M, et al. Gan To Kagaku Ryoho. 2025 Dec;52(13):1285-1287. Gan To Kagaku Ryoho. 2025. PMID: 41546323 Japanese.
Breast cancer(BC)is the most common cancer among Japanese women aged 30-39 years. In recent years, the impact of oncofertility has become an important issue. In Gifu prefecture, the oncofertility network was established to provide information regarding cancer treatm …
Breast cancer(BC)is the most common cancer among Japanese women aged 30-39 years. In recent years, the impact of oncofertility has be …
Comparison of Fertility-Related Recommendations Across National Comprehensive Cancer Network, ASCO, Clinical Oncology Society of Australia, and European Society for Medical Oncology Guidelines for People With Cancer Comparing Fertility Recommendations for People With Cancer.
Bhinder JK, Peera M, Al-Khaifi M. Bhinder JK, et al. JCO Oncol Pract. 2026 Jan 14:OP2500545. doi: 10.1200/OP-25-00545. Online ahead of print. JCO Oncol Pract. 2026. PMID: 41534015 Review.
PURPOSE: Oncofertility, a multidisciplinary field that integrates oncology and reproductive medicine, is a vital component of comprehensive cancer care. ...All guidelines highlight the importance of multidisciplinary care, including specialized oncofertility counsel …
PURPOSE: Oncofertility, a multidisciplinary field that integrates oncology and reproductive medicine, is a vital component of compreh …
Advances, Mechanisms, and Clinical Perspectives for the In Vitro Maturation of Human Oocytes.
Gargallo-Alonso M, Picton HM, Malo C. Gargallo-Alonso M, et al. Int J Mol Sci. 2025 Dec 19;27(1):5. doi: 10.3390/ijms27010005. Int J Mol Sci. 2025. PMID: 41515886 Free PMC article. Review.
Furthermore, we examine the translational and clinical applications of IVM in human fertility treatment, highlighting its efficacy in PCOS and oncofertility cases, and the limitations that persist in replicating in vivo conditions. Emerging technologies such as microfluidi …
Furthermore, we examine the translational and clinical applications of IVM in human fertility treatment, highlighting its efficacy in PCOS a …
Longitudinal Analysis of Male Fertility Using an Acr-Luc Knock-In Mouse Model: A Preclinical Platform for Reproductive Toxicity Testing.
Fukunaga H, Seino R, Matsuya Y, Takashima H, Ishikawa M, Onodera Y, Shirato H, Miyata H, Prise KM. Fukunaga H, et al. MedComm (2020). 2026 Jan 4;7(1):e70568. doi: 10.1002/mco2.70568. eCollection 2026 Jan. MedComm (2020). 2026. PMID: 41492361 Free PMC article.
The Acr-Luc KI model provides a reliable preclinical platform for reproductive toxicity testing and offers broad utility for studies in reproductive biology, toxicology, and oncofertility research....
The Acr-Luc KI model provides a reliable preclinical platform for reproductive toxicity testing and offers broad utility for studies in repr …
Radiation‑induced impacts on female fertility and fecundity: perspectives from the viewpoint of radiation protection.
Fukunaga H, Hamada N. Fukunaga H, et al. Int J Radiat Biol. 2026 Jan 5:1-5. doi: 10.1080/09553002.2025.2606997. Online ahead of print. Int J Radiat Biol. 2026. PMID: 41490211 Review.
In contrast, evidence from occupational and environmental exposures is scarce, with most studies addressing miscarriage or perinatal outcomes rather than infertility itself. CONCLUSIONS: While advances in oncofertility research have clarified therapeutic risks, systematic …
In contrast, evidence from occupational and environmental exposures is scarce, with most studies addressing miscarriage or perinatal outcome …
Bridging gaps in oncofertility: evaluation of reproductive dysfunction and fertility assessment in pediatric cancer survivors.
Sarangarajan S, Singh SD, Singh A, Setlur K, Banerjee S, Singh N, Malhotra N, Gupta AK, Meena JP, Seth R. Sarangarajan S, et al. Support Care Cancer. 2025 Dec 27;34(1):57. doi: 10.1007/s00520-025-10284-4. Support Care Cancer. 2025. PMID: 41455091
BACKGROUND: With improved survival in pediatric cancers, late effects such as reproductive dysfunction and infertility have emerged as a major concern. Oncofertility services remain underdeveloped in India, particularly in public sector institutions. ...CONCLUSION: There i …
BACKGROUND: With improved survival in pediatric cancers, late effects such as reproductive dysfunction and infertility have emerged as a maj …
Validation of the Oncofertility Support Scale derived from the Fertility Information Support scale among young adult women with breast cancer.
Hu L, Chau PH, Wu C, Choi EPH. Hu L, et al. Support Care Cancer. 2025 Dec 19;34(1):48. doi: 10.1007/s00520-025-10250-0. Support Care Cancer. 2025. PMID: 41419649 Free PMC article.
There is a growing demand for reliable tools to assess and enhance oncofertility support. This study aimed to validate a tool assessing oncofertility support. ...Both Cronbach's alpha and McDonald's omega were 0.95. CONCLUSION: The Oncofertility Support Scale …
There is a growing demand for reliable tools to assess and enhance oncofertility support. This study aimed to validate a tool assessi …
How we do it in Gdansk - practical approach to fertility preservation in pediatric female cancer patients.
Mulewska A, Lukaszuk K, Kufel-Grabowska J, Hennig M, Irga-Jaworska N. Mulewska A, et al. Ginekol Pol. 2025 Nov 18. doi: 10.5603/gpl.106025. Online ahead of print. Ginekol Pol. 2025. PMID: 41250596 Free article.
Premature ovarian insufficiency (POI) and infertility, which are the consequences of the gonadotoxic effects of anticancer therapy, have a profound impact on the quality of life of the affected individuals. A rapidly evolving field of oncofertility has emerged in an attemp …
Premature ovarian insufficiency (POI) and infertility, which are the consequences of the gonadotoxic effects of anticancer therapy, have a p …
Paediatric and adolescent fertility preservation procedural training and service provision: A qualitative study exploring views of clinicians in Australia and New Zealand.
Paynter C, Edib Z, Le A, Assis M, King S, Lantsberg D, Gook D, Nightingale M, Moeed S, Drever N, Jayasinghe Y. Paynter C, et al. J Pediatr Surg. 2025 Nov 12;61(2):162808. doi: 10.1016/j.jpedsurg.2025.162808. Online ahead of print. J Pediatr Surg. 2025. PMID: 41238051 Free article.
METHODS: Semi-structured interviews were conducted with multidisciplinary oncofertility experts from Australia and New Zealand. Data analysis of interview transcripts used the Framework Method. ...Reproductive laboratory staff requested bereavement training to better prepa …
METHODS: Semi-structured interviews were conducted with multidisciplinary oncofertility experts from Australia and New Zealand. Data …
Can We Improve Pregnancy Rates in Hormone Receptor-Positive Breast Cancer After Endocrine Therapy? The Role of Fertility Preservation Beyond Gonadotoxic Therapy.
Luciani MV, Mangili G, Papaleo E, Biancardi R, Vanni VS, Masciangelo R, Di Mattei VE, Candiani M, Cioffi R. Luciani MV, et al. Cancers (Basel). 2025 Oct 30;17(21):3498. doi: 10.3390/cancers17213498. Cancers (Basel). 2025. PMID: 41228290 Free PMC article.
Methods: This single-center prospective cohort study evaluated BC patients counseled at the Oncofertility Unit of San Raffaele Hospital (2012-2024). Results: Of 251 BC patients who received counseling, 39 met the inclusion criteria. ...
Methods: This single-center prospective cohort study evaluated BC patients counseled at the Oncofertility Unit of San Raffaele Hospit …
Male infertility as a late side effect of oncological treatment of Hodgkin lymphoma in childhood and adolescents and the possible prevention.
Prusak M, Brylka K, Derwich K. Prusak M, et al. Front Oncol. 2025 Oct 27;15:1655444. doi: 10.3389/fonc.2025.1655444. eCollection 2025. Front Oncol. 2025. PMID: 41220951 Free PMC article. Review.
Pediatric physicians experience challenges in oncofertility that hinder the provision of high-quality fertility preservation care and patients endure a multitude of physical and psychological consequences that can exacerbate long-term fertility outcomes. ...
Pediatric physicians experience challenges in oncofertility that hinder the provision of high-quality fertility preservation care and …
Fertility preservation practices and gastrointestinal oncologist in Europe: a pan-European study.
Ben-Aharon I, Goshen-Lago T, Puccini A, Alsina M, Arnold D, van Laarhoven H, Elme A, Buffart T, Fokter-Dovnik N, Sokop T, Obermanova R, Lordick F, Papamichael D, Sclafani F, Elez E, Taieb J. Ben-Aharon I, et al. Oncologist. 2025 Nov 11;30(11):oyaf350. doi: 10.1093/oncolo/oyaf350. Oncologist. 2025. PMID: 41206059 Free PMC article.
While there is abundant evidence on oncofertility outcomes in breast cancer and hematological malignancies, data regarding these perspectives in GI cancers is lacking. ...There is a need to disseminate and educate GI oncologists on oncofertility perspectives and con …
While there is abundant evidence on oncofertility outcomes in breast cancer and hematological malignancies, data regarding these pers …
Live Birth in a 50-Year-Old Breast Cancer Survivor Using a Cryopreserved Embryo: A Case Report.
Taguchi S. Taguchi S. Cureus. 2025 Sep 26;17(9):e93319. doi: 10.7759/cureus.93319. eCollection 2025 Sep. Cureus. 2025. PMID: 41158883 Free PMC article.
This case represents a remarkable success achieved despite the combined challenges of advanced maternal age and a cancer diagnosis, highlighting the importance of persistent embryo banking and oncofertility....
This case represents a remarkable success achieved despite the combined challenges of advanced maternal age and a cancer diagnosis, highligh …
RNA-seq Splicing Profile of the CDH1 Gene and Its Impact on the Clinical Pathogenicity Classification of CDH1 Variants: A Description of Alternative and Pathogenic Splicing Patterns.
Sebai M, Tang R, Adnani Y, Fievet A, Cabaret O, Robert de Rancher MA, Auger N, Elaribi Y, Jilani H, Limacher JM, Caron O, Jemaa LB, Rouleau E. Sebai M, et al. Cancers (Basel). 2025 Oct 14;17(20):3320. doi: 10.3390/cancers17203320. Cancers (Basel). 2025. PMID: 41154377 Free PMC article.
Childbearing in women diagnosed with cancer during reproductive age.
Esposito G, Cantarutti A, Franchi M, Peccatori FA, Scarfone G, Negri E, Corrao G, Parazzini F, La Vecchia C. Esposito G, et al. Acta Obstet Gynecol Scand. 2025 Dec;104(12):2309-2319. doi: 10.1111/aogs.70071. Epub 2025 Oct 27. Acta Obstet Gynecol Scand. 2025. PMID: 41144834 Free PMC article.
Decreasing barriers to the utilization of cryopreserved sperm in male cancer survivors: an expert review and guide.
Alexander MV, Ciomperlik H, Reynolds AC, Nevins A, Ghidei L, Kassab J, Campbell K, Sullivan J, Jochum MD, Detti L, Woodard TL, Lipshultz LI, McKenzie LJ. Alexander MV, et al. Oncologist. 2025 Dec 1;30(12):oyaf280. doi: 10.1093/oncolo/oyaf280. Oncologist. 2025. PMID: 41138163 Free PMC article. Review.
Key intervention timepoints are examined, including the post-treatment fertility return visit, long-term cryopreservation while remote from family building, readiness for family building, and posthumous considerations. We subsequently outline an optimal Oncofertility Patie …
Key intervention timepoints are examined, including the post-treatment fertility return visit, long-term cryopreservation while remote from …
Reflections on Sperm Banking Decisions and Support Needs Among Adolescent Males and Their Caregivers 1 Year After Cancer Diagnosis: A Qualitative Study.
Karkare T, Roche CI, Griffith MM, Quinn GP, O'Brien SH, Stanek CJ, Klosky JL, Colton Z, Audino A, Yeager N, Whiteside S, English J, Gerhardt CA, Nahata L. Karkare T, et al. Pediatr Blood Cancer. 2026 Jan;73(1):e32128. doi: 10.1002/pbc.32128. Epub 2025 Oct 22. Pediatr Blood Cancer. 2026. PMID: 41126487 Clinical Trial.
CONCLUSION: Despite satisfaction with the oncofertility consultation at diagnosis, clinical teams should prioritize fertility education moving forward and allow additional time for sperm banking decision-making (when possible) at diagnosis. ...
CONCLUSION: Despite satisfaction with the oncofertility consultation at diagnosis, clinical teams should prioritize fertility educati …
Oncofertility outcomes after fertility-sparing surgery in infertile BOT patients: results of a large retrospective study on controlled ovarian stimulation.
Liang L, Zhen XM, Li Y, Ma CH, Yang S, Yan J, Song XL, Li R. Liang L, et al. Front Oncol. 2025 Sep 29;15:1592600. doi: 10.3389/fonc.2025.1592600. eCollection 2025. Front Oncol. 2025. PMID: 41089516 Free PMC article.
This study aimed to evaluate the impact of controlled ovarian stimulation (COS) on oncofertility outcomes in infertile women with BOT after FSS. METHODS: This retrospective observational study was conducted at the Reproductive Medical Center, Peking University Third Hospit …
This study aimed to evaluate the impact of controlled ovarian stimulation (COS) on oncofertility outcomes in infertile women with BOT …
Fertility and ovarian function preservation in young women with breast cancer: A joint analysis of the Joven & Fuerte and PREFER prospective studies.
Mesa-Chavez F, Razeti MG, Blondeaux E, Platas A, Delucchi V, Fonseca A, Fontana V, Cruz-Ramos M, Anserini P, Gracía Garza MR, Chiappe E, Mohar A, Orlando L, Cabrera-Galeana P, Cinieri S, Bargallo-Rocha E, Del Mastro L, Villarreal-Garza C, Lambertini M. Mesa-Chavez F, et al. Breast. 2025 Oct 1:104592. doi: 10.1016/j.breast.2025.104592. Online ahead of print. Breast. 2025. PMID: 41067958 Free article.
CONCLUSION: FP and ovarian protection uptake were markedly higher in Italy than Mexico, possibly reflecting divergent social and healthcare contexts, though cryopreservation remained underutilized in both countries. Improved access to oncofertility services is warranted to …
CONCLUSION: FP and ovarian protection uptake were markedly higher in Italy than Mexico, possibly reflecting divergent social and healthcare …
RANKL and CSF-1 are elevated in periovulatory follicular fluid of BRCA1 mutation carriers and increase proinflammatory signaling in fallopian tube epithelial cells.
Kollara A, Madaan V, Zhang J, Greenblatt EM, Brown TJ. Kollara A, et al. Neoplasia. 2025 Dec;70:101237. doi: 10.1016/j.neo.2025.101237. Epub 2025 Oct 8. Neoplasia. 2025. PMID: 41067178 Free PMC article.
Follicular fluid was collected from 59 patients diagnosed with breast cancer undergoing controlled ovarian stimulation and oocyte retrieval as part of their oncofertility treatment. Samples included 13 patients with confirmed BRCA1 mutations, 15 patients with mutations in …
Follicular fluid was collected from 59 patients diagnosed with breast cancer undergoing controlled ovarian stimulation and oocyte retrieval …
DNA damage response signaling in oocytes from an oncofertility perspective.
Song YS, Zhang J, Bo Y, Zhang Q, Kim SY, Xiao S. Song YS, et al. Biol Reprod. 2026 Jan 11;114(1):1-11. doi: 10.1093/biolre/ioaf207. Biol Reprod. 2026. PMID: 40966604 Review.
Although several protein molecules such as DNA damage-sensing kinases, checkpoint kinases, p53 family transcription factors, and pro-apoptotic molecules have been discovered, the precise mechanisms of DDR in determining the fate of oocytes, particularly how they differ from those …
Although several protein molecules such as DNA damage-sensing kinases, checkpoint kinases, p53 family transcription factors, and pro-apoptot …
Comprehensive Fertility Management After Pituitary Adenoma Surgery: Lessons from a Rural Japanese Case and Practical Review.
Numahata D, Kojo K, Ishikawa SE, Kuramae T, Nakazono A, Yanagida K, Nishiyama H, Takayama T. Numahata D, et al. Reports (MDPI). 2025 Aug 15;8(3):144. doi: 10.3390/reports8030144. Reports (MDPI). 2025. PMID: 40843886 Free PMC article.
Despite early engagement with neurosurgery teams, fertility management was delayed by the absence of on-site endocrinology expertise and limited local oncofertility resources. After comprehensive endocrine evaluation and counseling, the patient began combined human chorion …
Despite early engagement with neurosurgery teams, fertility management was delayed by the absence of on-site endocrinology expertise and lim …
Perspectives and Motivational Factors Surrounding Decision-Making in Women With Cancer Considering Fertility Preservation.
Dinh T, Kanji S, Farnell N, Ronn R, Pio G, Xu X, Dixit S, Greenblatt EM. Dinh T, et al. J Obstet Gynaecol Can. 2025 Oct;47(10):103074. doi: 10.1016/j.jogc.2025.103074. Epub 2025 Aug 15. J Obstet Gynaecol Can. 2025. PMID: 40818525
OBJECTIVES: To assess perspectives of patients referred for urgent oncofertility consultation influencing whether to proceed or decline fertility preservation (FP). METHODS: An online survey was conducted in newly diagnosed cancer patients from August 2021 to July 2023 aft …
OBJECTIVES: To assess perspectives of patients referred for urgent oncofertility consultation influencing whether to proceed or decli …
Safety of having a subsequent pregnancy after prior diagnosis of breast cancer during pregnancy in young BRCA carriers.
Perachino M, Blondeaux E, Delucchi V, Bernstein Molho R, Frank S, Paluch-Shimon S, Linn S, Di Meglio A, Peccatori F, Moore HCF, Parokonnaya A, Renaud T, Rodriguez Wallberg KA, Partridge AH, Pogoda K, Ferrari A, Wildiers H, Toss A, Rousset-Jablonski C, Kim HJ, Varela M, Cordoba O, Tanase Damian C, Marhold M, Fabi A, Graff SL, Rodriguez-Hernandez A, Okano M, Duchnowska R, Luna Pais H, Di Rocco R, Azim HA Jr, Mariamidze E, Kourie HR, Arecco L, Carrasco E, Agostinetto E, Balmana J, Saura C, Lambertini M. Perachino M, et al. ESMO Open. 2025 Aug;10(8):105513. doi: 10.1016/j.esmoop.2025.105513. Epub 2025 Aug 13. ESMO Open. 2025. PMID: 40811881 Free PMC article.
Artificial Gametogenesis and In Vitro Spermatogenesis: Emerging Strategies for the Treatment of Male Infertility.
Kaltsas A, Kyrgiafini MA, Markou E, Koumenis A, Mamuris Z, Dimitriadis F, Zachariou A, Chrisofos M, Sofikitis N. Kaltsas A, et al. Int J Mol Sci. 2025 Jul 30;26(15):7383. doi: 10.3390/ijms26157383. Int J Mol Sci. 2025. PMID: 40806512 Free PMC article. Review.
Particular attention is given to clinical applicability in contexts such as NOA, oncofertility preservation in prepubertal patients, genetic syndromes, and reprocutive scenarios involving same-sex or unpartnered individuals. ...
Particular attention is given to clinical applicability in contexts such as NOA, oncofertility preservation in prepubertal patients, …
Predicting ovarian function loss after chemotherapy and anti-HER2 therapy in young breast cancer patients.
Lambertini M, Allegranza D, Laubender RP, Harbeck N, Swain SM, Geyer CE, Slamon DJ, Bobba G, Lambertini C, de Haas S, Restuccia E, Vaz-Luis I, Cameron DA, Krop IE, Winer EP, Anderson RA. Lambertini M, et al. J Natl Cancer Inst. 2025 Nov 1;117(11):2317-2326. doi: 10.1093/jnci/djaf198. J Natl Cancer Inst. 2025. PMID: 40796347 Free PMC article. Clinical Trial.
BACKGROUND: The ability to predict ovarian function loss after anticancer treatment is important for appropriate oncofertility counseling and to aid in therapy decision-making for young women with early breast cancer (eBC). ...
BACKGROUND: The ability to predict ovarian function loss after anticancer treatment is important for appropriate oncofertility counse …
The silent protectors: how neutrophils influence female fertility during cancer treatment - a narrative review.
Obeagu EI. Obeagu EI. Ann Med Surg (Lond). 2025 Jul 16;87(8):5062-5069. doi: 10.1097/MS9.0000000000003526. eCollection 2025 Aug. Ann Med Surg (Lond). 2025. PMID: 40787542 Free PMC article. Review.
This review examines the dual role of neutrophils in female fertility during cancer treatment, particularly focusing on how they influence ovarian function and oncofertility. Chemotherapy and radiation, commonly used in cancer treatment, induce inflammatory responses that …
This review examines the dual role of neutrophils in female fertility during cancer treatment, particularly focusing on how they influence o …
Developing clinical practice guidelines in paediatric and adolescent oncofertility.
Kaur H, Assis M, Bhargava A, Edib Z, Navarro-Perez D, Ameratunga D, Anazodo A, Handelsman D, Julania S, McCarthy M, Peate M, Raiti L, Rozen G, Western P, Jayasinghe Y; Australian New Zealand Consortium in Oncofertility Clinical Trials Network Guidelines Group. Kaur H, et al. Best Pract Res Clin Obstet Gynaecol. 2025 Sep;102:102637. doi: 10.1016/j.bpobgyn.2025.102637. Epub 2025 Jul 11. Best Pract Res Clin Obstet Gynaecol. 2025. PMID: 40780099 Free article. Review.
Recent international guidelines in child, adolescent, and young adult (CAYA) oncofertility uniformly recommend fertility discussion before cancer treatment, and individualised decision-making for fertility preservation procedures. ...This paper provides an overview of CAYA …
Recent international guidelines in child, adolescent, and young adult (CAYA) oncofertility uniformly recommend fertility discussion b …
Fertility preservation and mental health among cancer patients of reproductive age.
Stal J, Benedict C, Partridge AH, Pozo-Kaderman C, Mack JW. Stal J, et al. Fertil Steril. 2025 Oct;124(4):612-618. doi: 10.1016/j.fertnstert.2025.07.007. Epub 2025 Aug 5. Fertil Steril. 2025. PMID: 40764167 Review.
Integrating mental health into clinical models of oncofertility care delivery is critical to ensure that patients with new, persistent, or worsening psychological symptoms are captured and appropriately cared for. ...
Integrating mental health into clinical models of oncofertility care delivery is critical to ensure that patients with new, persisten …
Pediatric and Adolescent Considerations for the Revised ASCO Guidelines.
Meacham LR, Ketterl TG, Bjornard KL, Nahata L, Gomez-Lobo V, Close AG, Rotz SJ, Dwiggins ML, Hoefgen HR, Kayiira A, van den Heuvel-Eibrink M; Leadership Committee of the Pediatric and Adolescent Committee of the Oncofertility Consortium. Meacham LR, et al. J Clin Oncol. 2025 Oct;43(28):3134-3135. doi: 10.1200/JCO-25-00882. Epub 2025 Jul 31. J Clin Oncol. 2025. PMID: 40743493 No abstract available.
Cancer and fertility management: FIGO best practice advice.
Purandare N, Ruiloba F, Nguyen-Hoang L, Wilailak S, Yanaihara N, Chung JPW, Malhotra J, Mocanu E, Amant F, McNally O, Peters I, Flynn K, El Helali A, Maxwell C, Adam S, Bergman L, Nanda S, Guinto VT, McAuliffe FM, Nelson-Piercy C, Nana M, Smith G, Berek J, O'Reilly S, O'Brien P, Jacobsson B, Poon LC; FIGO Committee on the Impact of Pregnancy on Long‐term Health and the FIGO Division of Maternal and Newborn Health and in collaboration with the FIGO Committee on Women's Cancer and the FIGO Committee on Reproductive Medicine, Endocrinology and Infertility. Purandare N, et al. Int J Gynaecol Obstet. 2025 Oct;171(1):32-44. doi: 10.1002/ijgo.70426. Epub 2025 Jul 31. Int J Gynaecol Obstet. 2025. PMID: 40739998 Free PMC article.
A Children's Oncology Group Survey Exploring Practices and Barriers to Sperm Banking for Post-Pubertal Males with Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia.
Feuerstein JL, Appel B. Feuerstein JL, et al. J Adolesc Young Adult Oncol. 2025 Jul 28. doi: 10.1177/21565333251364084. Online ahead of print. J Adolesc Young Adult Oncol. 2025. PMID: 40719606
Most institutions offering SB have a dedicated oncofertility team (57%), and 86% are medium- or large-sized, suggesting greater resource availability. ...
Most institutions offering SB have a dedicated oncofertility team (57%), and 86% are medium- or large-sized, suggesting greater resou …
Evaluating Trends in Fertility Counseling among Reproductive-Age Patients with Breast Cancer.
Yuen S, McCool K, Bharucha M, Narloch K, Zhu J, Yong H. Yuen S, et al. Ann Surg Oncol. 2025 Oct;32(11):8425-8431. doi: 10.1245/s10434-025-17857-x. Epub 2025 Jul 24. Ann Surg Oncol. 2025. PMID: 40707736 Free PMC article.
INTRODUCTION: Treatment-related infertility remains a paramount concern for young breast cancer patients. While emphasis on oncofertility is increasing, provision of fertility preservation remains suboptimal. This study evaluated oncofertility counseling (OC) and re …
INTRODUCTION: Treatment-related infertility remains a paramount concern for young breast cancer patients. While emphasis on oncofertility …
Semen quality in acute leukemia patients: a retrospective study.
Buonacquisto A, Del Principe MI, Pallotti F, Bianchini S, Buzzatti E, Caponecchia L, Chiaretti S, Cicolani G, Conflitti AC, Di Chiano S, Fucci L, Kasmi D, Minotti C, Paterno G, Tiravanti I, Venditti A, Lombardo F, Paoli D. Buonacquisto A, et al. Ann Hematol. 2025 Aug;104(8):4071-4080. doi: 10.1007/s00277-025-06426-7. Epub 2025 Jul 25. Ann Hematol. 2025. PMID: 40707629 Free PMC article.
Current Practices in the Use of Anti-Mullerian Hormone for Surveillance of Ovarian Function in Childhood Cancer Survivors: A Report from the Pediatric and Adolescent Committee of the Oncofertility Consortium.
Bjornard K, Close A, Rios J, Anazodo A, Levine J, Yu C, Nahata L, Meacham L. Bjornard K, et al. J Adolesc Young Adult Oncol. 2025 Jul 14. doi: 10.1177/21565333251359617. Online ahead of print. J Adolesc Young Adult Oncol. 2025. PMID: 40658204
Methods: Pediatric and adolescent committee (PAC) members of the Oncofertility Consortium were invited by email to complete a survey regarding ovarian reserve surveillance and their use of AMH. ...
Methods: Pediatric and adolescent committee (PAC) members of the Oncofertility Consortium were invited by email to complete a survey …
Digital health interventions for oncofertility in female patients: a systematic review.
Ha J, Kim M, Park H. Ha J, et al. Womens Health Nurs. 2025 Jun;31(2):119-129. doi: 10.4069/whn.2025.06.13. Epub 2025 Jun 30. Womens Health Nurs. 2025. PMID: 40639861 Free PMC article.
PURPOSE: The importance of fertility preservation during cancer treatment is increasingly emphasized, and the provision of oncofertility care has gained significant attention. This study aims to systematically collect and analyze research on digital interventions related t …
PURPOSE: The importance of fertility preservation during cancer treatment is increasingly emphasized, and the provision of oncofertility …
Oncolactation for Patients with Breast Cancer: Executive Summary from the American Society of Breast Surgeons.
Johnson HM, Miller ME, Mitchell KB; American Society of Breast Surgeons’ Research Committee. Johnson HM, et al. Ann Surg Oncol. 2025 Jul 8;32(12):8720-7. doi: 10.1245/s10434-025-17742-7. Online ahead of print. Ann Surg Oncol. 2025. PMID: 40627104 Free PMC article. Review.
Despite increasing rates of pregnancy-related and postpartum breast cancers and growing recognition of oncofertility as an important component of survivorship, few guidelines exist to guide surgical oncologists in managing lactation during or after breast cancer treatment. …
Despite increasing rates of pregnancy-related and postpartum breast cancers and growing recognition of oncofertility as an important …
The effects of cancer treatments on uterine function.
Greenberg E, Strage K, Ozimek N, Abdur-Rashid K, Turan G, Milgrom S, Appiah L. Greenberg E, et al. Best Pract Res Clin Obstet Gynaecol. 2025 Sep;102:102629. doi: 10.1016/j.bpobgyn.2025.102629. Epub 2025 Jun 27. Best Pract Res Clin Obstet Gynaecol. 2025. PMID: 40618531 Review.
Pre- and post-treatment consultation with oncofertility specialists is critical in assessing a patient's risk of uterine injury from a proposed cancer treatment plan as well as understanding treatment-induced injury to optimize fertility preservation....
Pre- and post-treatment consultation with oncofertility specialists is critical in assessing a patient's risk of uterine injury from …
Oncologic and fertility outcomes of progestin therapy for atypical hyperplasia and grade 1 cancer of the endometrium: Results of a specialized oncofertility program.
Dzyubak O, Glass K, Watts M, Tarafdar O, Simpson AN, Maganti M, Deljoomanesh S, Laframboise S, Bernardini MQ, Pakbaz S, Hodgson A, Clarke B, Rouzbahman M, Chawla T, Zad T, Kim SR, Ferguson SE. Dzyubak O, et al. Gynecol Oncol. 2025 Aug;199:72-78. doi: 10.1016/j.ygyno.2025.06.015. Epub 2025 Jun 30. Gynecol Oncol. 2025. PMID: 40592024
OBJECTIVE: This study describes the oncological and fertility outcomes of patients with atypical hyperplasia (AH) or low-grade endometrial cancer (EC) desiring fertility preservation, enrolled in a specialized oncofertility program. METHODS: Patients referred between 2019 …
OBJECTIVE: This study describes the oncological and fertility outcomes of patients with atypical hyperplasia (AH) or low-grade endometrial c …
Oncofertility and female fertility preservation: a clinical update.
Christianson MS. Christianson MS. Menopause. 2025 Jul 1;32(7):655-657. doi: 10.1097/GME.0000000000002558. Menopause. 2025. PMID: 40586592 Review.
This Practice Pearl will focus on fertility preservation options for women facing medical treatment, a core component of oncofertility....
This Practice Pearl will focus on fertility preservation options for women facing medical treatment, a core component of oncofertility …
[Specificities of breast cancer management in AYAs].
Coussy F, Laas E, Cao K, Hamy AS, Loirat D, Laurence V. Coussy F, et al. Bull Cancer. 2025 Jul-Aug;112(7-8):853-859. doi: 10.1016/j.bulcan.2025.04.004. Epub 2025 Jun 26. Bull Cancer. 2025. PMID: 40579303 Free article. Review. French.
Breast cancer in adolescents and young adults (AYAs) is a rare event but requires a well-structured and tailored approach for this specific population. Oncogenetic and oncofertility consultations are essential at the time of breast cancer diagnosis in an AYA. ...
Breast cancer in adolescents and young adults (AYAs) is a rare event but requires a well-structured and tailored approach for this specific …
Are guidelines guiding? A mixed methods study examining the integration of ASCO fertility discussion guidelines in practice among oncologists and adolescents and young adults at an NCI-designated Comprehensive Cancer Center.
Stal J, Yi SY, Roche CI, Freyer DR, Kim SE, Milam JE, In GK, Miller KA. Stal J, et al. J Cancer Surviv. 2025 Jun 19. doi: 10.1007/s11764-025-01850-0. Online ahead of print. J Cancer Surviv. 2025. PMID: 40536662
RESULTS: Themes reported by oncologists (N = 12; 66.7% female, on average in practice for 14.3 years) included a lack of oncofertility-related training and limited knowledge surrounding fertility discussion guidelines. ...Discussions were primarily informed by patient need …
RESULTS: Themes reported by oncologists (N = 12; 66.7% female, on average in practice for 14.3 years) included a lack of oncofertility …
[Pregnancy after breast cancer].
Loison R, Kotur de Castelbajac V. Loison R, et al. Bull Cancer. 2025 Jul-Aug;112(7-8):860-866. doi: 10.1016/j.bulcan.2025.04.001. Epub 2025 Jun 17. Bull Cancer. 2025. PMID: 40533298 Review. French.
Despite potentially gonadotoxic treatments, fertility following breast cancer treatment remains satisfactory. Oncofertility has advanced, and an increasing number of patients benefit from oocyte or embryo cryopreservation techniques. ...
Despite potentially gonadotoxic treatments, fertility following breast cancer treatment remains satisfactory. Oncofertility has advan …
Partnership and fatherhood outcomes in young men diagnosed with cancer: a nationwide register-based study.
Bentsen L, Pappot H, Macklon KT, Schmidt L, Vassard D. Bentsen L, et al. J Cancer Surviv. 2025 Jun 10. doi: 10.1007/s11764-025-01849-7. Online ahead of print. J Cancer Surviv. 2025. PMID: 40493159
IMPLICATIONS FOR CANCER SURVIVORS: The lower probability of fatherhood highlights the need for and importance of oncofertility counseling, timely fertility preservation referrals, and follow-up care tailored to cancer groups and age at diagnosis....
IMPLICATIONS FOR CANCER SURVIVORS: The lower probability of fatherhood highlights the need for and importance of oncofertility counse …
Fertility preservation through oocyte or embryo vitrification prior to oncological treatment: a 12-year experience.
Zimmermann A, Perrin J, Deveze C, Saias-Magnan J, Guillemain C, Courbiere B. Zimmermann A, et al. J Assist Reprod Genet. 2025 May;42(5):1453-1459. doi: 10.1007/s10815-025-03522-5. Epub 2025 May 30. J Assist Reprod Genet. 2025. PMID: 40447956
METHODS: We conducted a retrospective, single-center, descriptive cohort study, including women who underwent fertility preservation through oocyte or embryo cryopreservation before a medium risk of gonadotoxicity chemotherapy for cancer at our Department of Reproductive Medicine …
METHODS: We conducted a retrospective, single-center, descriptive cohort study, including women who underwent fertility preservation through …
Rescue in vitro maturation of germinal vesicle oocytes after ovarian stimulation: the importance of the culture media.
Soler N, Cimadomo D, Escrich L, Grau N, Galán A, Alamá P, de Los Santos MJ, Rienzi L, Escribá MJ. Soler N, et al. Hum Reprod. 2025 Aug 1;40(8):1504-1515. doi: 10.1093/humrep/deaf099. Hum Reprod. 2025. PMID: 40447125 Free PMC article.
These oocytes may be valuable to poor prognosis patients when alternatives are not available and to oncofertility patients. Nonetheless, although rescue in vitro maturation (r-IVM) is experiencing a comeback, clear good practice recommendations regarding inherent protocols …
These oocytes may be valuable to poor prognosis patients when alternatives are not available and to oncofertility patients. Nonethele …
Development and pilot of Trainers in Oncofertility Reproductive Communication and Health (TORCH) program.
Jalili D, Zabar S, Rose J, Shah R, Tancer L, Augusto B, Vadaparampil ST, Quinn GP. Jalili D, et al. J Cancer Surviv. 2025 May 24. doi: 10.1007/s11764-025-01828-y. Online ahead of print. J Cancer Surviv. 2025. PMID: 40413370
PURPOSE: To evaluate outcomes from the Trainers in Oncofertility Reproductive Communication and Health (TORCH) program, which trains Allied Health Professionals (AHPs) to become leaders in counseling AYA cancer patients on reproductive health. METHODS: ECHO-TORCH was devel …
PURPOSE: To evaluate outcomes from the Trainers in Oncofertility Reproductive Communication and Health (TORCH) program, which trains …
Hematologic cancers in women: from fertility preservation to post-cancer fertility outcomes.
Goldenberg E, Sonigo C, Rakrouki S, Vinolas C, Eustache F, Puy V, Willekens C, Lazarovici J, Sifer C, Becquart C, Mayeur A, Benoit A, Grynberg M, Peigné M. Goldenberg E, et al. Hum Reprod. 2025 Jul 1;40(7):1315-1324. doi: 10.1093/humrep/deaf071. Hum Reprod. 2025. PMID: 40302200
After adjustment, positive predictive factors for pregnancy were age <35 years, being in a relationship at the first oncofertility consultation, and absence of hematopoietic stem cell transplantation. LIMITATIONS, REASONS FOR CAUTION: Limitations include potential biase …
After adjustment, positive predictive factors for pregnancy were age <35 years, being in a relationship at the first oncofertility …
The prevalence of parental cancer history and in vitro fertilization utilization.
Chen AL, Li S, Baker VL, Lupo PJ, Nichols HB, Eisenberg ML, Luke B. Chen AL, et al. J Natl Cancer Inst. 2025 Jul 1;117(7):1485-1491. doi: 10.1093/jnci/djaf068. J Natl Cancer Inst. 2025. PMID: 40300782
CONCLUSIONS: Overall, 1.1% of all births and 3.0% of IVF-conceived births had at least 1 parent with a cancer history with an increasing prevalence over the study period, highlighting the importance of oncofertility programs....
CONCLUSIONS: Overall, 1.1% of all births and 3.0% of IVF-conceived births had at least 1 parent with a cancer history with an increasing pre …
Assisted reproductive technology in young BRCA carriers with a pregnancy after breast cancer: An international cohort study.
Magaton IM, Blondeaux E, Hamy AS, Linn S, Bernstein-Molho R, Peccatori FA, Ferrari A, Carrasco E, Paluch-Shimon S, Agostinetto E, Venturelli M, Luis IMV, Rodriguez-Wallberg KA, Kim HJ, Sorouri K, Renaud T, Moore HCF, Cui W, Bajpa J, Rousset-Jablonski C, De Marchis L, Yerushalmi R, Wong SM, Han S, Phillips KA, Pogoda K, Puglisi F, Chirco A, Duhoux FP, Meattini I, Villarreal-Garza C, Vernieri C, Bruzzone M, Demeestere I, Azim HA Jr, Partridge AH, Lambertini M. Magaton IM, et al. Eur J Cancer. 2025 Jun 3;222:115434. doi: 10.1016/j.ejca.2025.115434. Epub 2025 Apr 14. Eur J Cancer. 2025. PMID: 40300260 Free article.
Colon Cancer and Pregnancy.
Sacks OA, Davids JS. Sacks OA, et al. Clin Colon Rectal Surg. 2024 Jun 26;38(3):191-197. doi: 10.1055/s-0044-1787890. eCollection 2025 May. Clin Colon Rectal Surg. 2024. PMID: 40292002 Free PMC article. Review.
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