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Female Oncofertility and Immune Checkpoint Blockade in Melanoma: Where Are We Today?
Lee CL, Martinez E, Malon Gimenez D, Muniz TP, Butler MO, Saibil SD. Lee CL, et al. Cancers (Basel). 2025 Jan 13;17(2):238. doi: 10.3390/cancers17020238. Cancers (Basel). 2025. PMID: 39858020 Free article. Review.
Our review aims to give an overview of oncofertility practices among female melanoma patients after immunotherapy. We also focus on the literature gap in the published evidence and synthesize summaries regarding ICI toxicities on reproductive health and fetal development, …
Our review aims to give an overview of oncofertility practices among female melanoma patients after immunotherapy. We also focus on t …
Bridging the gap: An outlook of oncofertility care in Africa.
Odhiambo M, Muteshi C. Odhiambo M, et al. Int J Gynaecol Obstet. 2025 Jan 24. doi: 10.1002/ijgo.16175. Online ahead of print. Int J Gynaecol Obstet. 2025. PMID: 39853745 Review.
This article examines existing literature on oncofertility in Africa and explores the barriers to oncofertility care. Patient-level barriers include lack of awareness about fertility preservation options, financial constraints, and the heavy emotional burden of canc …
This article examines existing literature on oncofertility in Africa and explores the barriers to oncofertility care. Patient- …
Establishing oncofertility care in limited resource settings: a narrative review.
Kimelman D, Ozimek N. Kimelman D, et al. J Assist Reprod Genet. 2025 Jan 22. doi: 10.1007/s10815-025-03392-x. Online ahead of print. J Assist Reprod Genet. 2025. PMID: 39841345 Review.
PURPOSE: While the literature has addressed the implementation of oncofertility care at developed institutions, minimal advice exists for those seeking to build oncofertility programs in limited resource settings (LRS). Our research offers a promising conversation o …
PURPOSE: While the literature has addressed the implementation of oncofertility care at developed institutions, minimal advice exists …
Cancer therapy and reproductive impact.
Feldberg D, Purandare N. Feldberg D, et al. Int J Gynaecol Obstet. 2025 Jan 21. doi: 10.1002/ijgo.16174. Online ahead of print. Int J Gynaecol Obstet. 2025. PMID: 39836035
All patients where the cancer treatment has gonadotoxic potential should be referred for oncofertility advice. The effect of chemotherapy and radiotherapy on the human ovary can vary from no impact to full-blown premature ovarian failure due to hormonal and follicular depl …
All patients where the cancer treatment has gonadotoxic potential should be referred for oncofertility advice. The effect of chemothe …
Fertility preservation in cancer patients: Data collection, analysis, and continuous improvement of cryostorage.
Mocanu E, Barnea ER. Mocanu E, et al. Int J Gynaecol Obstet. 2025 Jan 16. doi: 10.1002/ijgo.16171. Online ahead of print. Int J Gynaecol Obstet. 2025. PMID: 39817432
Patient safety and return for cancer therapy takes priority in all oncofertility services. In certain cases, the intervention for female patients is contraindicated and, aside from extensive counseling, alternative methods of preserving fertility should be explored. ...
Patient safety and return for cancer therapy takes priority in all oncofertility services. In certain cases, the intervention for fem …
Reproductive cancer cryopreservation services: Patient information, clinical advice, and support.
Mocanu E, Purandare NC, Hull L. Mocanu E, et al. Int J Gynaecol Obstet. 2025 Jan 15. doi: 10.1002/ijgo.16172. Online ahead of print. Int J Gynaecol Obstet. 2025. PMID: 39812148
Fertility preservation services must offer information to patients, prior to their visit, so that they have time to read and digest the information, and also have the opportunity to write down any questions they wish to ask at the oncofertility consultation appointment. Ap …
Fertility preservation services must offer information to patients, prior to their visit, so that they have time to read and digest the info …
Position statement on the diagnosis and management of acute leukaemia and aggressive lymphomas in pregnancy.
Mills G, Shand A, Kennedy D, Lowe S, Bilsland V, Cutts B, McBride B, Brown W, Bolisetty S, Wegner EA, Kidson-Gerber G. Mills G, et al. Lancet Haematol. 2025 Jan 3:S2352-3026(24)00309-0. doi: 10.1016/S2352-3026(24)00309-0. Online ahead of print. Lancet Haematol. 2025. PMID: 39761682 Review.
We provide recommendations for diagnosis and staging, imaging safety in pregnancy, therapy in pregnancy incorporating a multidisciplinary approach, supportive care, oncofertility, and pregnancy and birth management. This Viewpoint was reviewed and endorsed by the councils …
We provide recommendations for diagnosis and staging, imaging safety in pregnancy, therapy in pregnancy incorporating a multidisciplinary ap …
Successful Fertility Preservation in a Case of Low-Grade Endometrial Stromal Sarcoma: A Multidisciplinary Approach Through the Oncofertility Network.
Ooi K, Wakimoto Y, Oki N, Sakata M, Mabuchi S. Ooi K, et al. Cureus. 2024 Nov 26;16(11):e74539. doi: 10.7759/cureus.74539. eCollection 2024 Nov. Cureus. 2024. PMID: 39735098 Free PMC article.
We document a case of fertility preservation in a 27-year-old nulligravida diagnosed with LGESS, which not only enabled the successful birth of two live infants but also underscores the efficacy of a multidisciplinary approach to patient treatment through the Hyogo Oncofertili …
We document a case of fertility preservation in a 27-year-old nulligravida diagnosed with LGESS, which not only enabled the successful birth …
Impact of cancer during reproductive age on the probability of livebirth after cancer: a register-based cohort study among Danish women aged 18-39 with and without cancer.
Bentsen L, Colmorn LB, Pappot H, Macklon KT, Vassard D. Bentsen L, et al. J Cancer Surviv. 2024 Dec 27. doi: 10.1007/s11764-024-01720-1. Online ahead of print. J Cancer Surviv. 2024. PMID: 39725841
IMPLICATIONS FOR CANCER SURVIVORS: Results underscore the importance of oncofertility counseling at diagnosis, referral to fertility specialist before treatment, and follow-up after cancer, focusing on cancer type, parity status, and age at diagnosis....
IMPLICATIONS FOR CANCER SURVIVORS: Results underscore the importance of oncofertility counseling at diagnosis, referral to fertility …
Contraception Use in Cancer Survivors, Clinical Practice and Patients' Preferences.
Asinaro G, Stigliani S, Chiappe E, Lambertini M, Massarotti C. Asinaro G, et al. Open Access J Contracept. 2024 Dec 11;15:135-143. doi: 10.2147/OAJC.S431366. eCollection 2024. Open Access J Contracept. 2024. PMID: 39678079 Free PMC article. Review.
Contraception counseling should start before oncological therapies, together with information regarding fertility and sexual health, preferably by the gynecologist of the oncofertility unit, with a specific expertise in dealing with cancer patients. Increased awareness of …
Contraception counseling should start before oncological therapies, together with information regarding fertility and sexual health, prefera …
Navigating an uncertain future: a qualitative study exploring thoughts about fertility and oncofertility counseling among young men with cancer.
Bentsen L, Aagesen M, Hjerming M, Jørgensen N, Pappot H. Bentsen L, et al. Support Care Cancer. 2024 Dec 13;33(1):28. doi: 10.1007/s00520-024-09066-1. Support Care Cancer. 2024. PMID: 39672967
Psychological and physical fertility issues often impact body image and masculinity during cancer. Oncofertility counseling is limited, usually brief at diagnosis; however, discussions on treatment-related fertility challenges remain sparse during follow-up. ...This unders …
Psychological and physical fertility issues often impact body image and masculinity during cancer. Oncofertility counseling is limite …
Oncofertility. A first world problem?
Grover SR. Grover SR. J Pediatr Adolesc Gynecol. 2024 Dec 11:S1083-3188(24)00348-6. doi: 10.1016/j.jpag.2024.12.003. Online ahead of print. J Pediatr Adolesc Gynecol. 2024. PMID: 39672255 No abstract available.
COVID-19 and Oncofertility: No SARS-CoV-2 in Semen but Inflammation Seems to Affect Sperm Parameters.
Chaput L, Pons-Rejraji H, Chabrolles H, Fiot M, Lucas C, Pereira B, Bonnet B, Haj Hamid R, Rives-Feraille A, Binois O, Ferreux L, Delepine B, Koscinski I, Lichtblau I, Giscard d'Estaing S, Bendayan M, Saias-Magnan J, Lousqui J, Henquell C, Brugnon F. Chaput L, et al. J Med Virol. 2024 Dec;96(12):e70070. doi: 10.1002/jmv.70070. J Med Virol. 2024. PMID: 39648939 Free PMC article.
#infertility in Brazil: an analysis of authorship and post content on Instagram.
Carneiro MM, Koga CN, Mussi MCL, Fradico PF, Carneiro MM. Carneiro MM, et al. JBRA Assist Reprod. 2024 Dec 2;28(4):678-682. doi: 10.5935/1518-0557.20240081. JBRA Assist Reprod. 2024. PMID: 39626005 Free PMC article.
For oncofertility, the hashtags were #cancerandpregnancy, #oocytecryopreservation), #oncofertility, and #fertilitypreservation. ...CONCLUSIONS: Both HCP and LP write about major fertility topics on Instagram. Oncofertility appears to gain less attention. In B …
For oncofertility, the hashtags were #cancerandpregnancy, #oocytecryopreservation), #oncofertility, and #fertilitypreservation …
Fertility Preservation in Female Patients with Cancer. Part I: Challenges and Future Prospects in Developing Countries; A Narrative Review Study.
Mashhadi Meighani E, Yahyaei A, Ghaffari F. Mashhadi Meighani E, et al. Int J Fertil Steril. 2024 Oct 30;18(4):293-304. doi: 10.22074/ijfs.2024.2015626.1569. Int J Fertil Steril. 2024. PMID: 39564819 Free PMC article. Review.
While international guidelines on oncofertility practice have been published in developed countries, there is limited information available on oncofertility practice in developing countries, which often face limitations in their cancer health support networks. ...In …
While international guidelines on oncofertility practice have been published in developed countries, there is limited information ava …
Ovarian Tissue Cryopreservation in Pediatric Centers across the United States: Practice Patterns and Barriers.
Kebodeaux CA, Pruett M, Gomez-Lobo V, Nahata L, Saraf AJ, Hoefgen HR. Kebodeaux CA, et al. J Pediatr Adolesc Gynecol. 2024 Nov 16:S1083-3188(24)00341-3. doi: 10.1016/j.jpag.2024.11.002. Online ahead of print. J Pediatr Adolesc Gynecol. 2024. PMID: 39557187
STUDY OBJECTIVE: To evaluate practice patterns in ovarian tissue cryopreservation (OTC) provision METHODS: US providers practicing or developing OTC in pediatric programs were invited to participate in a survey disseminated via the Oncofertility Consortium. RESULTS: Twenty …
STUDY OBJECTIVE: To evaluate practice patterns in ovarian tissue cryopreservation (OTC) provision METHODS: US providers practicing or develo …
Nationwide Survey on the Status of Oncofertility in Japan and Involvement of Embryologists in the Practice of Fertility Preservation.
Tomari H, Okitsu O, Mizuno S, Yabuuchi A, Okimura T, Kikuchi H, Furuyama S, Taniguchi K, Tamura I, Ota K, Fukuda Y, Horage Y, Suzuki N. Tomari H, et al. J Adolesc Young Adult Oncol. 2024 Nov 18. doi: 10.1089/jayao.2024.0032. Online ahead of print. J Adolesc Young Adult Oncol. 2024. PMID: 39552417
Purpose: To investigate the actual status of fertility preservation techniques in oncofertility in Japan and to clarify the involvement of embryologists in this field. Methods: This survey was conducted online, targeting embryologists working at 622 facilities registered w …
Purpose: To investigate the actual status of fertility preservation techniques in oncofertility in Japan and to clarify the involveme …
Oncofertility Research: A Review of the Literature.
Dinicu AI, Frisch EH, Kim H, Yu C, Beffa L, Richards EG. Dinicu AI, et al. J Womens Health (Larchmt). 2024 Nov 18. doi: 10.1089/jwh.2024.0235. Online ahead of print. J Womens Health (Larchmt). 2024. PMID: 39552413
Conclusions: There is an urgent need for more prospective research in oncofertility. While fertility care in the setting of gynecological cancer is a collaborative effort between the specialties of gynecological oncology and REI, this partnership is not reflected in the au …
Conclusions: There is an urgent need for more prospective research in oncofertility. While fertility care in the setting of gynecolog …
Limited Recommendations and Evidence for Timing and Frequency of Anti-Mullerian Hormone Screening in Female Pediatric Cancer Survivors: A Systematic Review from the Pediatric and Adolescent Committee of the Oncofertility Consortium.
Rotz SJ, Bjornard K, Hampanda K, Kumnick A, Maher JCY, Yu C, Appiah L. Rotz SJ, et al. J Adolesc Young Adult Oncol. 2024 Nov 18. doi: 10.1089/jayao.2024.0111. Online ahead of print. J Adolesc Young Adult Oncol. 2024. PMID: 39552408 Review.
The effects of BRCA1 and 2 mutations on ovarian reserve and aging.
Matevossian K, Sauerbrun-Cutler MT, Konda S, Chen A, Steckler A, Ou J, McAdams JN, Snegovskikh E, Cram R, Chen JT, Go M, Stuckey A, Grive KJ. Matevossian K, et al. Fertil Steril. 2024 Nov 7:S0015-0282(24)02377-X. doi: 10.1016/j.fertnstert.2024.11.001. Online ahead of print. Fertil Steril. 2024. PMID: 39515452 No abstract available.
Oncofertility in Children and Adolescents.
Jayasinghe YL, Ginsburg E. Jayasinghe YL, et al. Obstet Gynecol Clin North Am. 2024 Dec;51(4):711-730. doi: 10.1016/j.ogc.2024.08.007. Epub 2024 Sep 21. Obstet Gynecol Clin North Am. 2024. PMID: 39510740 Review.
Major improvements have been seen in oncofertility care over the last decade. Clinical ethics frameworks support new populations, including children, having access to novel fertility preservation techniques. Oncofertility consultation requires a multidisciplinary ap …
Major improvements have been seen in oncofertility care over the last decade. Clinical ethics frameworks support new populations, inc …
Availability of Adolescent and Young Adult-Specific Sexual and Reproductive Health Programs and Resources: A Review of the Websites of National Cancer Institute-Designated Cancer Centers.
Adillon L, Stalls JM, Nguyen U, Liu I, Arthur SS, Shelby RA, Corbett C, Dorfman CS. Adillon L, et al. J Adolesc Young Adult Oncol. 2024 Oct 28. doi: 10.1089/jayao.2024.0118. Online ahead of print. J Adolesc Young Adult Oncol. 2024. PMID: 39460930
No AYA-specific sexual health programs were found. Oncofertility programs were presented on 56% (n = 5) of cancer centers and 50% (n = 29) of comprehensive cancer center websites. ...
No AYA-specific sexual health programs were found. Oncofertility programs were presented on 56% (n = 5) of cancer centers and 50% (n …
New Insights on In Vitro Maturation of Oocytes for Fertility Preservation.
Gotschel F, Sonigo C, Becquart C, Sellami I, Mayeur A, Grynberg M. Gotschel F, et al. Int J Mol Sci. 2024 Oct 1;25(19):10605. doi: 10.3390/ijms251910605. Int J Mol Sci. 2024. PMID: 39408934 Free PMC article. Review.
In the last decade, the evolution of oncofertility has sparked a resurgence of interest in in vitro maturation (IVM) due to its suitability in certain oncological scenarios where controlled ovarian hyperstimulation may not be feasible. ...
In the last decade, the evolution of oncofertility has sparked a resurgence of interest in in vitro maturation (IVM) due to its suita …
A Mega-Analysis of Anti-Müllerian Hormone Levels in Female Childhood Cancer Survivors Based on Treatment Risk, Time since Treatment, and Pubertal Status.
Yano Maher JC, Kumnick A, Sinaii N, Su HI, Cameron KE, George SA, Gracia C, Meacham LR, Gomez-Lobo V. Yano Maher JC, et al. J Adolesc Young Adult Oncol. 2024 Sep 23. doi: 10.1089/jayao.2024.0093. Online ahead of print. J Adolesc Young Adult Oncol. 2024. PMID: 39308417
Anti-Mullerian hormone (AMH) helps evaluate ovarian reserve, and the 2020 Oncofertility Pediatric Initiative Network (O-PIN) risk stratification is utilized to counsel risk of gonadal dysfunction/infertility. ...
Anti-Mullerian hormone (AMH) helps evaluate ovarian reserve, and the 2020 Oncofertility Pediatric Initiative Network (O-PIN) risk str …
Ovarian tissue autotransplantation improves longevity in mice.
Ruhliada NN. Ruhliada NN. Front Physiol. 2024 Aug 29;15:1443494. doi: 10.3389/fphys.2024.1443494. eCollection 2024. Front Physiol. 2024. PMID: 39268190 Free PMC article.
The function of the transplanted fragment is usually limited to 6-12 months. This is enough for oncofertility purposes, sometimes, but not for longevity improvement. We performed periodical tissue return (autologous transplantation), containing both the cortex and medulla …
The function of the transplanted fragment is usually limited to 6-12 months. This is enough for oncofertility purposes, sometimes, bu …
[Factors Influencing Oncofertility in Gynecological Cancer Patients: Application of Mixed Methods Study].
Kim M, Ha J. Kim M, et al. J Korean Acad Nurs. 2024 Aug;54(3):418-431. doi: 10.4040/jkan.23151. J Korean Acad Nurs. 2024. PMID: 39248426 Korean.
PURPOSE: This study aimed to identify factors influencing oncofertility and to explore the oncofertility experiences of patients with gynecological cancer using quantitative and qualitative methods, respectively. ...Qualitative results showed three theme clusters an …
PURPOSE: This study aimed to identify factors influencing oncofertility and to explore the oncofertility experiences of patien …
Fertility-sparing treatment and follow-up in patients with cervical cancer, ovarian cancer, and borderline ovarian tumours: guidelines from ESGO, ESHRE, and ESGE.
Morice P, Scambia G, Abu-Rustum NR, Acien M, Arena A, Brucker S, Cheong Y, Collinet P, Fanfani F, Filippi F, Eriksson AGZ, Gouy S, Harter P, Matias-Guiu X, Pados G, Pakiz M, Querleu D, Rodolakis A, Rousset-Jablonski C, Stepanyan A, Testa AC, Macklon KT, Tsolakidis D, De Vos M, Planchamp F, Grynberg M. Morice P, et al. Lancet Oncol. 2024 Nov;25(11):e602-e610. doi: 10.1016/S1470-2045(24)00262-6. Epub 2024 Aug 28. Lancet Oncol. 2024. PMID: 39216500
The developmental process of these guidelines is based on a systematic literature review and critical appraisal involving an international multidisciplinary development group consisting of 25 experts from relevant disciplines (ie, gynaecological oncology, oncofertility, re …
The developmental process of these guidelines is based on a systematic literature review and critical appraisal involving an international m …
Oncofertility and Fertility Preservation for Women with Gynecological Malignancies: Where Do We Stand Today?
Di Nisio V, Daponte N, Messini C, Anifandis G, Antonouli S. Di Nisio V, et al. Biomolecules. 2024 Aug 3;14(8):943. doi: 10.3390/biom14080943. Biomolecules. 2024. PMID: 39199331 Free PMC article. Review.
Oncofertility is a growing medical and research field that includes two main areas: oncology and reproductive medicine. ...
Oncofertility is a growing medical and research field that includes two main areas: oncology and reproductive medicine. ...
Knowledge, attitudes, and practices of healthcare providers among women oncofertility in Iran: a cross-sectional study.
Ghaemi M, Rokhzadi I, Dashtkoohi M, Doosti M, Rezaeinejad M, Shariat M, Hantoushzadeh S, Keikha F, Eshraghi N, Fakehi M. Ghaemi M, et al. BMC Cancer. 2024 Aug 24;24(1):1044. doi: 10.1186/s12885-024-12821-6. BMC Cancer. 2024. PMID: 39182018 Free PMC article.
This has led to an emerging challenge in the field of oncofertility, which seeks to address the impact of cancer treatments on fertility and endeavors to preserve reproduction. ...METHODS: A cross-sectional study was conducted to assess healthcare providers' knowledge, att …
This has led to an emerging challenge in the field of oncofertility, which seeks to address the impact of cancer treatments on fertil …
Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome.
Ho WJ, Marinova MB, Listijono DR, Bertoldo MJ, Richani D, Kim LJ, Brown A, Riepsamen AH, Cabot S, Frost ER, Bustamante S, Zhong L, Selesniemi K, Wong D, Madawala R, Marchante M, Goss DM, Li C, Araki T, Livingston DJ, Turner N, Sinclair DA, Walters KA, Homer HA, Gilchrist RB, Wu LE. Ho WJ, et al. EMBO Mol Med. 2024 Oct;16(10):2583-2618. doi: 10.1038/s44321-024-00119-w. Epub 2024 Aug 21. EMBO Mol Med. 2024. PMID: 39169162 Free PMC article.
The Importance of Fertility Preservation in the Transgender Population.
Parikh N, Chattha A, Fredrickson JR, Walker D, Zhao Y, Gargollo P, Granberg C. Parikh N, et al. Urology. 2025 Jan;195:91-95. doi: 10.1016/j.urology.2024.08.020. Epub 2024 Aug 21. Urology. 2025. PMID: 39154839
While cost concerns and insurance coverage regarding oncofertility is a prominent area of discussion, the transgender community is often excluded. ...
While cost concerns and insurance coverage regarding oncofertility is a prominent area of discussion, the transgender community is of …
Mapping ethical, legal, and social implications (ELSI) of fertility preservation.
Alon I, Bussod I, Golan OC, Ravitsky V. Alon I, et al. J Assist Reprod Genet. 2024 Sep;41(9):2495-2514. doi: 10.1007/s10815-024-03210-w. Epub 2024 Aug 14. J Assist Reprod Genet. 2024. PMID: 39141169 Review.
RESEARCH QUESTION: The study examines the ethical, legal, and social implications of fertility preservation, highlighting its importance across oncofertility, elective egg freezing, and posthumous assisted reproduction, as well as its impact on transgender individuals unde …
RESEARCH QUESTION: The study examines the ethical, legal, and social implications of fertility preservation, highlighting its importance acr …
Fertility preservation in pediatric central nervous system tumors: A report from the Children's Oncology Group.
Felker J, Bjornard K, Close A, Chavez J, Chow EJ, Meacham LR, Burns K. Felker J, et al. Pediatr Blood Cancer. 2024 Nov;71(11):e31246. doi: 10.1002/pbc.31246. Epub 2024 Aug 10. Pediatr Blood Cancer. 2024. PMID: 39126374
The Oncofertility Consortium Pediatric Initiative Network has published recommendations about the risks of infertility due to gonadotoxic therapy. ...
The Oncofertility Consortium Pediatric Initiative Network has published recommendations about the risks of infertility due to gonadot …
A Cross-Sectional Survey of Healthcare Professionals' Knowledge, Attitude and Current Behaviours towards Female Fertility Preservation Services within the UK.
Kasaven LS, Mitra A, Chawla M, Murugesu S, Anson N, Ben Nagi J, Theodorou E, Rimmer MP; UKARCOG Working Group; Al-Wattar B, Yazbek J, Jones BP, Saso S. Kasaven LS, et al. Cancers (Basel). 2024 Jul 25;16(15):2649. doi: 10.3390/cancers16152649. Cancers (Basel). 2024. PMID: 39123377 Free PMC article.
The Low Survivability of Transplanted Gonadal Grafts: The Impact of Cryopreservation and Transplantation Conditions on Mitochondrial Function.
Moniz I, Soares M, Sousa AP, Ramalho-Santos J, Branco A. Moniz I, et al. Biology (Basel). 2024 Jul 18;13(7):542. doi: 10.3390/biology13070542. Biology (Basel). 2024. PMID: 39056734 Free PMC article. Review.
This review aims to discuss the limitations of oncofertility protocols with a focus on the impacts of mitochondrial dysfunction, oxidative stress, and the loss of antioxidant defense in graft integrity....
This review aims to discuss the limitations of oncofertility protocols with a focus on the impacts of mitochondrial dysfunction, oxid …
Pharmacological methods for ovarian function and fertility preservation in women with cancer: A literature review.
Cvetanovic AS, Lambertini M, Punie K, Matovina Brko GG, Zivkovic ND, Popovic MJ, Milovic Kovacevic MM, Popovic LS. Cvetanovic AS, et al. Oncol Res. 2024 Jul 17;32(8):1309-1322. doi: 10.32604/or.2024.049743. eCollection 2024. Oncol Res. 2024. PMID: 39055889 Free PMC article. Review.
Oncofertility is an extremely significant topic that is increasingly being discussed owing to increased evidence indicating that fertility preservation does not affect the treatment outcomes of patients with cancer but significantly contributes to preserving life quality. …
Oncofertility is an extremely significant topic that is increasingly being discussed owing to increased evidence indicating that fert …
A dozen years of ovarian tissue cryopreservation at a pediatric hospital: tracking program and patient metrics while adapting to increasing needs.
McElhinney KL, Kennedy T, Rowell EE, Laronda MM. McElhinney KL, et al. F S Rep. 2024 Feb 16;5(2):197-204. doi: 10.1016/j.xfre.2024.02.009. eCollection 2024 Jun. F S Rep. 2024. PMID: 38983744 Free PMC article.
CONCLUSION: During the first 12 years of this program, oncofertility research increased, annual tissue cryopreservation cases increased, and the median age of those who underwent OTC decreased. ...
CONCLUSION: During the first 12 years of this program, oncofertility research increased, annual tissue cryopreservation cases increas …
Current practices in oncofertility counseling: updated evidence on fertility preservation and post-treatment pregnancies in young women affected by early breast cancer.
Arecco L, Borea R, Magaton IM, Janković K, Mariamizde E, Stana M, Scavone G, Ottonello S, Spinaci S, Genova C, de Azambuja E, Lambertini M. Arecco L, et al. Expert Rev Anticancer Ther. 2024 Sep;24(9):803-817. doi: 10.1080/14737140.2024.2372337. Epub 2024 Jul 9. Expert Rev Anticancer Ther. 2024. PMID: 38913581 Review.
AREAS COVERED: This review aims to cover all the latest available evidence in the field of oncofertility, including the gonadotoxicity of currently adopted anticancer therapies in the curative breast cancer setting, the available strategies for fertility preservation and t …
AREAS COVERED: This review aims to cover all the latest available evidence in the field of oncofertility, including the gonadotoxicit …
Fertility and Pregnancy-Related Issues in Young BRCA Carriers With Breast Cancer.
Magaton IM, Arecco L, Mariamidze E, Jankovic K, Stana M, Buzzatti G, Trevisan L, Scavone G, Ottonello S, Fregatti P, Massarotti C, von Wolff M, Lambertini M. Magaton IM, et al. Breast Cancer (Auckl). 2024 Jun 14;18:11782234241261429. doi: 10.1177/11782234241261429. eCollection 2024. Breast Cancer (Auckl). 2024. PMID: 38882447 Free PMC article. Review.
Spermatogonial quantity in prepubertal boys undergoing fertility preservation is comparable between haematological and non-haematological cancers.
Tholeti P, Koulmane Laxminarayana SL, Lakshmi VR, Bhat VK, Kumar P V, Uppangala S, Kalthur G, Spears N, Adiga SK. Tholeti P, et al. Hum Fertil (Camb). 2024 Dec;27(1):2362980. doi: 10.1080/14647273.2024.2362980. Epub 2024 Jun 6. Hum Fertil (Camb). 2024. PMID: 38842163 Free article.
Fertility restoration potential of immature testicular tissue (ITT) depends on the number of spermatogonial cells in the retrieved tissue prior to cryopreservation in oncofertility programme. There are limited data on the association between type of malignancy and testicul …
Fertility restoration potential of immature testicular tissue (ITT) depends on the number of spermatogonial cells in the retrieved tissue pr …
Fertility Preservation in BRCA1/2 Germline Mutation Carriers: An Overview.
Silvestris E, Cormio G, Loizzi V, Corrado G, Arezzo F, Petracca EA. Silvestris E, et al. Life (Basel). 2024 May 10;14(5):615. doi: 10.3390/life14050615. Life (Basel). 2024. PMID: 38792636 Free PMC article. Review.
In this regard, fertility preservation (FP) procedures should be discussed in oncofertility counseling-from the first line of prevention with risk-reducing salpingo-oophorectomy (RRSO) to the new experimental ovarian stem cells (OSCs) model as a new way to obtain in vitro- …
In this regard, fertility preservation (FP) procedures should be discussed in oncofertility counseling-from the first line of prevent …
Oncofertility as an Essential Part of Comprehensive Cancer Treatment in Patients of Reproductive Age, Adolescents and Children.
Łubik-Lejawka D, Gabriel I, Marzec A, Olejek A. Łubik-Lejawka D, et al. Cancers (Basel). 2024 May 13;16(10):1858. doi: 10.3390/cancers16101858. Cancers (Basel). 2024. PMID: 38791937 Free PMC article. Review.
This review discusses the impact of oncological treatments on the ovarian reserve with a thorough explanation of oncologic treatments' effects and modes of oncofertility procedures. The aim of this review is to help clinicians in making an informed decision about post-trea …
This review discusses the impact of oncological treatments on the ovarian reserve with a thorough explanation of oncologic treatments' effec …
"Infertility Isn't a Choice!": Conversations on Twitter about the Financial Burden of Oncofertility Care.
Corey SL, Ari A, Sonpatki M, Drizin JH, Gorman JR. Corey SL, et al. J Adolesc Young Adult Oncol. 2024 Dec;13(6):876-881. doi: 10.1089/jayao.2024.0035. Epub 2024 May 13. J Adolesc Young Adult Oncol. 2024. PMID: 38738476
This study aimed to evaluate how the adolescent and young adult (AYA) cancer community utilized Twitter to discuss the financial challenges of oncofertility care and to advocate for change. Tweets related to oncofertility and finances (n = 166), collected over a 12- …
This study aimed to evaluate how the adolescent and young adult (AYA) cancer community utilized Twitter to discuss the financial challenges …
The Australian New Zealand Consortium in Children, Adolescents, and Young Adults Oncofertility action plan.
Lau LS, Allingham C, Anazodo A, Sullivan M, Peate M, Hunter S, Stern C, Ryan AL, Super L, Orme LM, McCarthy M, Gook D, Lewin J, Marino J, Ryan J, Downie P, Manudhane R, Winstanley M, Pettit T, Lantsberg D, Irving H, Reid S, Heath JA, Kabalan-Baeza P, Wanaguru D, Moore L, Gillam L, Zacharin M, Assis M, Rozen G, Hunter T, Julania S, Sharwood E, Ameratunga D, Jayasinghe Y; ANZCO Clinical Trial Network. Lau LS, et al. Pediatr Blood Cancer. 2024 Jul;71(7):e31041. doi: 10.1002/pbc.31041. Epub 2024 May 7. Pediatr Blood Cancer. 2024. PMID: 38715224
International and national oncofertility networks, including the US-led Oncofertility Consortium, FertiProtekt, and the Danish Network, have played pivotal roles in advancing the discipline of oncofertility over the last decade. Many other countries lack a sh …
International and national oncofertility networks, including the US-led Oncofertility Consortium, FertiProtekt, and the Danish …
Multiplexed serum biomarkers to discriminate nonviable and ectopic pregnancy.
Barnhart KT, Bollig KJ, Senapati S, Takacs P, Robins JC, Haisenleder DJ, Beer LA, Savaris RF, Koelper NC, Speicher DW, Chittams J, Bao J, Wen Z, Feng Y, Kim M, Mumford S, Shen L, Gimotty P. Barnhart KT, et al. Fertil Steril. 2024 Sep;122(3):482-493. doi: 10.1016/j.fertnstert.2024.04.028. Epub 2024 Apr 26. Fertil Steril. 2024. PMID: 38677710
Changing the Perspective on Fertility Preservation for Women with Metastatic or Advanced Stage Cancer.
Abel MK, Wang A, Letourneau JM, Melisko ME, Cedars MI, Rosen MP. Abel MK, et al. Curr Oncol Rep. 2024 Jun;26(6):583-592. doi: 10.1007/s11912-024-01530-9. Epub 2024 Apr 19. Curr Oncol Rep. 2024. PMID: 38639793 Review.
While there have been tremendous advances and advocacy in the field of oncofertility, there has been limited focus on patients with advanced stage or metastatic cancer. ...
While there have been tremendous advances and advocacy in the field of oncofertility, there has been limited focus on patients with a …
A Qualitative Exploration of Oncology Clinician's Needs for PGT-M Discussions in Clinical Practice.
Schioppo DA, Greenwood JPH, Miller KA, Vig HS. Schioppo DA, et al. J Adolesc Young Adult Oncol. 2024 Aug;13(4):646-651. doi: 10.1089/jayao.2023.0142. Epub 2024 Apr 17. J Adolesc Young Adult Oncol. 2024. PMID: 38629661
Participants desire a streamlined referral pathway to professionals trained in oncofertility to help address their patient's reproductive needs. Conclusion: Our study identified that educational and referral resources to reproductive specialists are needed to maximize repr …
Participants desire a streamlined referral pathway to professionals trained in oncofertility to help address their patient's reproduc …
Let's TOC Fertility: A stepped wedge cluster randomized controlled trial of the Telehealth Oncofertility Care (TOC) intervention in children, adolescent and young adult cancer survivors.
Romero SAD, Au L, Flores-Ortega RE, Helsten T, Palomino H, Kaiser BN, Echevarria M, Lukas K, Freeman K, Zou J, Aristizabal P, Armenian S, Su HI. Romero SAD, et al. Contemp Clin Trials. 2024 Jun;141:107537. doi: 10.1016/j.cct.2024.107537. Epub 2024 Apr 13. Contemp Clin Trials. 2024. PMID: 38614445 Clinical Trial.
Despite longstanding clinical guidelines, oncofertility care delivery continues to be limited and highly variable across adult and pediatric oncology settings. ...Intervention components are: 1) electronic health record-based oncofertility needs screen and referral …
Despite longstanding clinical guidelines, oncofertility care delivery continues to be limited and highly variable across adult and pe …
Future Fertility Among Pediatric Cancer Patients: Experiences and Perspectives of Health Workers in a Low-Resource Setting.
Kayiira A, McLaughlin S, John JN, Zaake D, Xiong S, Balagadde JK, Gomez-Lobo V, Wabinga H, Ghebre R. Kayiira A, et al. J Adolesc Young Adult Oncol. 2024 Aug;13(4):637-645. doi: 10.1089/jayao.2024.0011. Epub 2024 Apr 13. J Adolesc Young Adult Oncol. 2024. PMID: 38613474
This study explores the experiences and perspectives of oncology health care professionals in Uganda to identify contextual barriers and facilitators to addressing oncofertility in low-resource settings. Methods: Using ground theory, we conducted in-depth face-to-face inte …
This study explores the experiences and perspectives of oncology health care professionals in Uganda to identify contextual barriers and fac …
Assessing Attitudes and Understanding After Ovarian Tissue Cryopreservation: A Follow-Up Telephone Interview Survey.
Piselli A, Yano JC, Gomez-Lobo V. Piselli A, et al. J Adolesc Young Adult Oncol. 2024 Aug;13(4):622-628. doi: 10.1089/jayao.2023.0148. Epub 2024 Apr 8. J Adolesc Young Adult Oncol. 2024. PMID: 38597904
A questionnaire developed by The Pediatric Initiative Network of the Oncofertility Consortium, modified to assess intent and attitudes regarding OTC, tissue access knowledge, financial burden of tissue storage, and intent to use tissue, was utilized. ...
A questionnaire developed by The Pediatric Initiative Network of the Oncofertility Consortium, modified to assess intent and attitude …
Fertility preservation in pediatric solid tumors: A report from the Children's Oncology Group.
Bjornard K, Close A, Burns K, Chavez J, Chow EJ, Meacham LR. Bjornard K, et al. Pediatr Blood Cancer. 2024 Jun;71(6):e30960. doi: 10.1002/pbc.30960. Epub 2024 Mar 26. Pediatr Blood Cancer. 2024. PMID: 38532279
Risk for gonadal dysfunction/infertility was assessed based on gonadotoxic therapies, sex, and pubertal status and assigned as minimal, significant, and high following the Oncofertility Consortium Pediatric Initiative Network (PIN) risk stratification. Most protocols (65.6 …
Risk for gonadal dysfunction/infertility was assessed based on gonadotoxic therapies, sex, and pubertal status and assigned as minimal, sign …
Expansion of the Fertility Preservation Program to All Newly Diagnosed Prepubertal Patients with Cancer at a Pediatric Hospital.
Leavitt AP, Albritton KH, Cazzell M, Stevenson E. Leavitt AP, et al. J Pediatr Hematol Oncol Nurs. 2024 May-Jun;41(3):212-219. doi: 10.1177/27527530231221134. Epub 2024 Mar 24. J Pediatr Hematol Oncol Nurs. 2024. PMID: 38523328
Results: Between July 15, 2022 and October 30, 2022, 54 patients' treatment plans were evaluated to determine treatment-related infertility risk using the Oncofertility Consortium Pediatric Initiative Network's Risk Assessment tool. Fifteen patients were at a high level of …
Results: Between July 15, 2022 and October 30, 2022, 54 patients' treatment plans were evaluated to determine treatment-related infertility …
Fertility and reproductive concerns related to the new generation of cancer drugs and the clinical implication for young individuals undergoing treatments for solid tumors.
Helgadottir H, Matikas A, Fernebro J, Frödin JE, Ekman S, Rodriguez-Wallberg KA. Helgadottir H, et al. Eur J Cancer. 2024 May;202:114010. doi: 10.1016/j.ejca.2024.114010. Epub 2024 Mar 11. Eur J Cancer. 2024. PMID: 38520926 Free article. Review.
The goal with this review is to gather the current knowledge regarding oncofertility and the different novel therapies, including immune checkpoint inhibitors, antibody-drug conjugates, small molecules and monoclonal antibody targeted therapies. ...
The goal with this review is to gather the current knowledge regarding oncofertility and the different novel therapies, including imm …
Fertility preservation in patients undergoing gonadotoxic treatments: a Canadian Fertility and Andrology Society clinical practice guideline.
Roberts JE, Benoit J, Foong S, Saumet J, Korkidakis A, Marr K, McQuillan S, Todd N. Roberts JE, et al. Reprod Biomed Online. 2024 May;48(5):103767. doi: 10.1016/j.rbmo.2023.103767. Epub 2023 Dec 15. Reprod Biomed Online. 2024. PMID: 38458057
This Canadian Fertility and Andrology Society (CFAS) guideline outlines the current understanding of social and medical issues associated with oncofertility, and the medical and surgical technologies available to optimize future fertility....
This Canadian Fertility and Andrology Society (CFAS) guideline outlines the current understanding of social and medical issues associated wi …
Assessing Knowledge, Counseling, and Referral Patterns Regarding Fertility Preservation Before Gonadotoxic Treatments Among Physicians in the Military Health System.
Boedeker D, Hunkler K, Pekny C, Watson N, Yamasaki M, Drayer S, Spitzer T. Boedeker D, et al. J Adolesc Young Adult Oncol. 2024 Aug;13(4):607-613. doi: 10.1089/jayao.2023.0162. Epub 2024 Mar 6. J Adolesc Young Adult Oncol. 2024. PMID: 38451721
Additionally, a 22-item survey was distributed to physicians practicing within the MHS assessing knowledge of reproductive health benefits, oncofertility counseling practices, and subspecialist referral patterns. Results: From 2020 to 2022, there were 31,103 individuals of …
Additionally, a 22-item survey was distributed to physicians practicing within the MHS assessing knowledge of reproductive health benefits, …
A 20-year overview of fertility preservation in boys: new insights gained through a comprehensive international survey.
Duffin K, Neuhaus N, Andersen CY, Barraud-Lange V, Braye A, Eguizabal C, Feraille A, Ginsberg JP, Gook D, Goossens E, Jahnukainen K, Jayasinghe Y, Keros V, Kliesch S, Lane S, Mulder CL, Orwig KE, van Pelt AMM, Poirot C, Rimmer MP, Rives N, Sadri-Ardekani H, Safrai M, Schlatt S, Stukenborg JB, van de Wetering MD, Wyns C, Mitchell RT. Duffin K, et al. Hum Reprod Open. 2024 Feb 16;2024(2):hoae010. doi: 10.1093/hropen/hoae010. eCollection 2024. Hum Reprod Open. 2024. PMID: 38449521 Free PMC article.
Ethical, legal, social, and policy issues of ovarian tissue cryopreservation in prepubertal girls: a critical interpretive review.
Affdal AO, Salama M, Ravitsky V. Affdal AO, et al. J Assist Reprod Genet. 2024 Apr;41(4):999-1026. doi: 10.1007/s10815-024-03059-z. Epub 2024 Mar 2. J Assist Reprod Genet. 2024. PMID: 38430324 Review.
Data were grouped into seven thematic categories: (1) risks of the procedure, (2) unique decision-making issues in pediatric oncofertility, (3) counseling, (4) cultural and cost issues, and (5) disposition of cryopreserved reproductive tissue. CONCLUSION: This first litera …
Data were grouped into seven thematic categories: (1) risks of the procedure, (2) unique decision-making issues in pediatric oncofertilit …
Uterine transposition in a patient with vulvar cancer.
Laufer J, Scasso S, Kimelman D, Olmedo C, Bentancor V, Soust A, Sotero G, Ribeiro R. Laufer J, et al. Gynecol Oncol Rep. 2024 Feb 14;52:101337. doi: 10.1016/j.gore.2024.101337. eCollection 2024 Apr. Gynecol Oncol Rep. 2024. PMID: 38404910 Free PMC article.
Fertility options after chemotherapy in young premenopausal patients.
Tanase A, Ciocoiu M, Tănase GV. Tanase A, et al. Acta Endocrinol (Buchar). 2023 Jul-Sep;19(3):398-402. doi: 10.4183/aeb.2023.398. Epub 2024 Feb 1. Acta Endocrinol (Buchar). 2023. PMID: 38356982 Free PMC article.
CONCLUSIONS: Improving survival rates and current data have created a new medical field oncofertility. The term was first introduced in 2015 and is being used all over clinics that treat young patients nowadays....
CONCLUSIONS: Improving survival rates and current data have created a new medical field oncofertility. The term was first introduced …
Fertility Potential and Gonadal Function in Survivors of Reduced-Intensity Hematopoietic Stem Cell Transplantation.
Rotz SJ, Hamilton BK, Wei W, Ahmed I, Winston SA, Ballard S, Bernard RJ, Carpenter P, Farhadfar N, Ferraro C, Friend BD, Gloude NJ, Hayashi RJ, Hoyle K, Jenssen K, Koo J, Lee CJ, Mariano L, Nawabit R, Ngwube A, Lalefar N, Phelan R, Perkins L, Rao A, Rayes A, Sandheinrich T, Stafford L, Tomlinson K, Whiteside S, Wiedl C, Myers K. Rotz SJ, et al. Transplant Cell Ther. 2024 May;30(5):534.e1-534.e13. doi: 10.1016/j.jtct.2024.02.002. Epub 2024 Feb 9. Transplant Cell Ther. 2024. PMID: 38342136
An update on oncofertility in prepubertal females.
Rashidian P. Rashidian P. J Gynecol Obstet Hum Reprod. 2024 Apr;53(4):102742. doi: 10.1016/j.jogoh.2024.102742. Epub 2024 Feb 9. J Gynecol Obstet Hum Reprod. 2024. PMID: 38341083 Review.
Due to the growing interest of the research community in the life prospects of young cancer survivors, there has been a demand to intersect reproductive medicine and oncology, which is referred to as "oncofertility". There are various fertility preservation options accordi …
Due to the growing interest of the research community in the life prospects of young cancer survivors, there has been a demand to intersect …
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