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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1959 1
1960 1
1968 1
1969 1
1983 1
1989 1
1996 1
1998 1
1999 7
2000 13
2001 23
2002 30
2003 61
2004 52
2005 87
2006 120
2007 116
2008 114
2009 151
2010 140
2011 122
2012 160
2013 115
2014 112
2015 132
2016 102
2017 116
2018 107
2019 101
2020 105
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1,886 results
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Page 1
Recent advances in oncolytic adenovirus therapies for cancer.
Rosewell Shaw A, Suzuki M. Rosewell Shaw A, et al. Curr Opin Virol. 2016 Dec;21:9-15. doi: 10.1016/j.coviro.2016.06.009. Epub 2016 Jul 2. Curr Opin Virol. 2016. PMID: 27379906 Free PMC article. Review.
Oncolytic adenoviruses (Onc.Ads) selectively replicate in and lyse cancer cells and are therefore commonly used vectors in clinical trials for cancer gene therapy. ...The hostile tumor microenvironment provides many barriers to efficient oncolytic virotherapy, as tu
Oncolytic adenoviruses (Onc.Ads) selectively replicate in and lyse cancer cells and are therefore commonly used vectors in clinical t
Oncolytic adenovirus: A tool for cancer therapy in combination with other therapeutic approaches.
Goradel NH, Mohajel N, Malekshahi ZV, Jahangiri S, Najafi M, Farhood B, Mortezaee K, Negahdari B, Arashkia A. Goradel NH, et al. J Cell Physiol. 2019 Jun;234(6):8636-8646. doi: 10.1002/jcp.27850. Epub 2018 Dec 4. J Cell Physiol. 2019. PMID: 30515798 Review.
Cancer therapy using oncolytic viruses is an emerging area, in which viruses are engineered to selectively propagate in tumor tissues without affecting healthy cells. ...Despite oncolytic adenoviruses ability in tumor cell lysis and immune responses stimulation, to …
Cancer therapy using oncolytic viruses is an emerging area, in which viruses are engineered to selectively propagate in tumor tissues …
Oncolytic adenovirus programmed by synthetic gene circuit for cancer immunotherapy.
Huang H, Liu Y, Liao W, Cao Y, Liu Q, Guo Y, Lu Y, Xie Z. Huang H, et al. Nat Commun. 2019 Oct 22;10(1):4801. doi: 10.1038/s41467-019-12794-2. Nat Commun. 2019. PMID: 31641136 Free PMC article.
By performing mouse model experiments and computational simulations, we find that replicable adenovirus has a superior tumor-killing efficacy than non-replicable adenovirus. ...Our results provide an effective strategy to engineer oncolytic adenovirus, …
By performing mouse model experiments and computational simulations, we find that replicable adenovirus has a superior tumor-killing …
Adenovirus DNA replication.
Hoeben RC, Uil TG. Hoeben RC, et al. Cold Spring Harb Perspect Biol. 2013 Mar 1;5(3):a013003. doi: 10.1101/cshperspect.a013003. Cold Spring Harb Perspect Biol. 2013. PMID: 23388625 Free PMC article. Review.
More recently these viruses have been used as gene-transfer vectors and oncolytic agents. On the other hand, adenoviruses are notorious pathogens in people with compromised immune functions. ...In addition, we will cover the development of antivirals that interfere with hu …
More recently these viruses have been used as gene-transfer vectors and oncolytic agents. On the other hand, adenoviruses are notorio …
Adenovirus vectors for gene therapy, vaccination and cancer gene therapy.
Wold WS, Toth K. Wold WS, et al. Curr Gene Ther. 2013 Dec;13(6):421-33. doi: 10.2174/1566523213666131125095046. Curr Gene Ther. 2013. PMID: 24279313 Free PMC article. Review.
Replication-competent (oncolytic) vectors are employed for cancer gene therapy. Oncolytic vectors are engineered to replicate preferentially in cancer cells and to destroy cancer cells through the natural process of lytic virus replication. Many clinical trials indi …
Replication-competent (oncolytic) vectors are employed for cancer gene therapy. Oncolytic vectors are engineered to replicate …
Oncolytic viruses: adenoviruses.
Niemann J, Kühnel F. Niemann J, et al. Virus Genes. 2017 Oct;53(5):700-706. doi: 10.1007/s11262-017-1488-1. Epub 2017 Jul 12. Virus Genes. 2017. PMID: 28702840 Review.
However, in recent years, oncolytic viruses have been recognized as therapeutic vehicles exhibiting multipronged anti-tumoral activity. ...With a focus on oncolytic adenoviruses, we will describe the efforts to restrict oncolytic virus infection to tumor tiss …
However, in recent years, oncolytic viruses have been recognized as therapeutic vehicles exhibiting multipronged anti-tumoral activit …
Innate immunity to adenovirus.
Hendrickx R, Stichling N, Koelen J, Kuryk L, Lipiec A, Greber UF. Hendrickx R, et al. Hum Gene Ther. 2014 Apr;25(4):265-84. doi: 10.1089/hum.2014.001. Epub 2014 Apr 8. Hum Gene Ther. 2014. PMID: 24512150 Free PMC article. Review.
Human adenoviruses are the most widely used vectors in gene medicine, with applications ranging from oncolytic therapies to vaccinations, but adenovirus vectors are not without side effects. In addition, natural adenoviruses pose severe risks for immunocompromised p …
Human adenoviruses are the most widely used vectors in gene medicine, with applications ranging from oncolytic therapies to vaccinati …
The Oncolytic Adenovirus DNX-2401 Has Antitumor Activity in Glioblastoma.
[No authors listed] [No authors listed] Cancer Discov. 2018 Apr;8(4):382. doi: 10.1158/2159-8290.CD-RW2018-031. Epub 2018 Feb 23. Cancer Discov. 2018. PMID: 29475886 Free article.
Viral and cellular interactions during adenovirus DNA replication.
Charman M, Herrmann C, Weitzman MD. Charman M, et al. FEBS Lett. 2019 Dec;593(24):3531-3550. doi: 10.1002/1873-3468.13695. Epub 2019 Dec 17. FEBS Lett. 2019. PMID: 31764999 Review.
Adenoviruses represent ubiquitous and clinically significant human pathogens, gene-delivery vectors, and oncolytic agents. The study of adenovirus-infected cells has long been used as an excellent model to investigate fundamental aspects of both DNA virus infection …
Adenoviruses represent ubiquitous and clinically significant human pathogens, gene-delivery vectors, and oncolytic agents. The study …
Virus, Oncolytic Virus and Human Prostate Cancer.
Liu GB, Zhao L, Zhang L, Zhao KN. Liu GB, et al. Curr Cancer Drug Targets. 2017;17(6):522-533. doi: 10.2174/1568009616666161216095308. Curr Cancer Drug Targets. 2017. PMID: 27993115 Review.
RESULTS: Mounting evidence suggests that infections with various viruses are causally linked to PCa pathogenesis. Published studies have provided strong evidence that at least two viruses (RXMV and HPV) contribute to prostate tumourigenicity and impact on the survival of p …
RESULTS: Mounting evidence suggests that infections with various viruses are causally linked to PCa pathogenesis. Published studies h …
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