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359 results
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Newcastle disease virus degrades SIRT3 via PINK1-PRKN-dependent mitophagy to reprogram energy metabolism in infected cells.
Gong Y, Tang N, Liu P, Sun Y, Lu S, Liu W, Tan L, Song C, Qiu X, Liao Y, Yu S, Liu X, Lin SH, Ding C. Gong Y, et al. Autophagy. 2022 Jul;18(7):1503-1521. doi: 10.1080/15548627.2021.1990515. Epub 2021 Oct 31. Autophagy. 2022. PMID: 34720029 Free PMC article.
Lacking a self-contained metabolism network, viruses have evolved multiple mechanisms for rewiring the metabolic system of their host to hijack the host's metabolic resources for replication. Newcastle disease virus (NDV) is a paramyxovirus, as an oncolyti …
Lacking a self-contained metabolism network, viruses have evolved multiple mechanisms for rewiring the metabolic system of their host to hij …
Molecular Mechanisms of Anti-Neoplastic and Immune Stimulatory Properties of Oncolytic Newcastle Disease Virus.
Schirrmacher V. Schirrmacher V. Biomedicines. 2022 Feb 28;10(3):562. doi: 10.3390/biomedicines10030562. Biomedicines. 2022. PMID: 35327364 Free PMC article. Review.
The present review provides an update of the molecular mechanisms of the anti-neoplastic and immune stimulatory properties of the avian paramyxovirus, Newcastle Disease Virus (NDV). The anti-neoplastic activities of NDV include (i) the endocytic targeting of …
The present review provides an update of the molecular mechanisms of the anti-neoplastic and immune stimulatory properties of the avian para …
Newcastle disease virus: current status and our understanding.
Ganar K, Das M, Sinha S, Kumar S. Ganar K, et al. Virus Res. 2014 May 12;184:71-81. doi: 10.1016/j.virusres.2014.02.016. Epub 2014 Mar 1. Virus Res. 2014. PMID: 24589707 Free PMC article. Review.
Newcastle disease (ND) is one of the highly pathogenic viral diseases of avian species. ...Newcastle disease virus (NDV) belongs to the family Paramyxoviridae and is well characterized member among the avian paramyxovirus serotypes. ...
Newcastle disease (ND) is one of the highly pathogenic viral diseases of avian species. ...Newcastle disease …
Newcastle-disease-virus-induced ferroptosis through nutrient deprivation and ferritinophagy in tumor cells.
Kan X, Yin Y, Song C, Tan L, Qiu X, Liao Y, Liu W, Meng S, Sun Y, Ding C. Kan X, et al. iScience. 2021 Jul 10;24(8):102837. doi: 10.1016/j.isci.2021.102837. eCollection 2021 Aug 20. iScience. 2021. PMID: 34368653 Free PMC article.
However, the mechanism by which ferroptosis mediates the response of tumor cells to oncolytic viruses remains poorly understood. The Newcastle disease virus (NDV) can selectively replicate in tumor cells. ...
However, the mechanism by which ferroptosis mediates the response of tumor cells to oncolytic viruses remains poorly understood. The …
Newcastle disease virus strain AF2240 as an oncolytic virus: A review.
Kalyanasundram J, Hamid A, Yusoff K, Chia SL. Kalyanasundram J, et al. Acta Trop. 2018 Jul;183:126-133. doi: 10.1016/j.actatropica.2018.04.007. Epub 2018 Apr 4. Acta Trop. 2018. PMID: 29626432 Free article. Review.
Since the classical oncolytic virus studies rely heavily on its natural oncolytic ability, virus manipulation was limited, thereby, restricted efforts to improve its safety. In order to circumvent such restriction, experiments involving non-human virus …
Since the classical oncolytic virus studies rely heavily on its natural oncolytic ability, virus manipulation wa …
Development of Molecular Mechanisms and Their Application on Oncolytic Newcastle Disease Virus in Cancer Therapy.
Huang F, Dai C, Zhang Y, Zhao Y, Wang Y, Ru G. Huang F, et al. Front Mol Biosci. 2022 Jul 4;9:889403. doi: 10.3389/fmolb.2022.889403. eCollection 2022. Front Mol Biosci. 2022. PMID: 35860357 Free PMC article. Review.
Newcastle disease virus (NDV) is a solid oncolytic agent capable of directly killing tumor cells and increasing tumor antigen exposure. ...We discussed the biological properties of NDV, the antitumor molecular mechanisms of oncolytic NDV, and it …
Newcastle disease virus (NDV) is a solid oncolytic agent capable of directly killing tumor cells and increasing …
Therapeutic potential of oncolytic Newcastle disease virus: a critical review.
Tayeb S, Zakay-Rones Z, Panet A. Tayeb S, et al. Oncolytic Virother. 2015 Mar 27;4:49-62. doi: 10.2147/OV.S78600. eCollection 2015. Oncolytic Virother. 2015. PMID: 27512670 Free PMC article. Review.
Newcastle disease virus (NDV) features a natural preference for replication in many tumor cells compared with normal cells. ...To further understand the oncolytic activity of NDV, we compared two NDV strains, ie, an attenuated virus (NDV-HUJ) an …
Newcastle disease virus (NDV) features a natural preference for replication in many tumor cells compared with normal ce …
Oncolytic Newcastle disease virus as a prospective anti-cancer therapy. A biologic agent with potential to break therapy resistance.
Schirrmacher V. Schirrmacher V. Expert Opin Biol Ther. 2015;15(12):1757-71. doi: 10.1517/14712598.2015.1088000. Epub 2015 Oct 5. Expert Opin Biol Ther. 2015. PMID: 26436571 Review.
INTRODUCTION: Oncolytic viruses (OVs) selectively replicate in tumor cells and cause cancer cell death. Most OVs in clinical studies are genetically engineered. In contrast, the avian Newcastle disease virus (NDV) is a naturally oncolytic RNA …
INTRODUCTION: Oncolytic viruses (OVs) selectively replicate in tumor cells and cause cancer cell death. Most OVs in clinical studies …
The oncolytic Newcastle disease virus as an effective immunotherapeutic strategy against glioblastoma.
Cuoco JA, Rogers CM, Mittal S. Cuoco JA, et al. Neurosurg Focus. 2021 Feb;50(2):E8. doi: 10.3171/2020.11.FOCUS20842. Neurosurg Focus. 2021. PMID: 33524945
Several investigators have reported the efficacy of experimental oncolytic viruses as demonstrated by improved long-term survival in cancer patients with advanced disease. Newcastle disease virus (NDV) is one of the most well-researched oncol …
Several investigators have reported the efficacy of experimental oncolytic viruses as demonstrated by improved long-term survival in …
Oncolytic Newcastle disease virus for cancer therapy: old challenges and new directions.
Zamarin D, Palese P. Zamarin D, et al. Future Microbiol. 2012 Mar;7(3):347-67. doi: 10.2217/fmb.12.4. Future Microbiol. 2012. PMID: 22393889 Free PMC article. Review.
Newcastle disease virus (NDV) is an avian paramyxovirus, which has been demonstrated to possess significant oncolytic activity against mammalian cancers. This review summarizes the research leading to the elucidation of the mechanisms of NDV-mediated o …
Newcastle disease virus (NDV) is an avian paramyxovirus, which has been demonstrated to possess significant oncolyti …
359 results