Past, Present and Future of Oncolytic Reovirus.
Cancers (Basel). 2020 Oct 31;12(11):3219. doi: 10.3390/cancers12113219.
Cancers (Basel). 2020.
PMID: 33142841
Free PMC article.
Review.
Mechanistic studies of oncolytic viruses (OVs) have revealed that most, if not all, OVs induce direct oncolysis and stimulate innate and adaptive anti-tumour immunity. With the advancement of tumour modelling, allowing characterisation of the effects of tumour microenviron …
Mechanistic studies of oncolytic viruses (OVs) have revealed that most, if not all, OVs induce direct oncolysis and stimulate innate …