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1951 1
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1959 3
1960 6
1961 1
1962 2
1963 4
1964 5
1965 2
1967 4
1968 1
1971 1
1972 2
1973 1
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1978 1
1982 1
1985 2
1986 1
1987 1
1989 3
1990 1
1991 2
1994 1
1995 1
1996 1
1997 1
1998 4
1999 12
2000 25
2001 30
2002 41
2003 51
2004 63
2005 100
2006 138
2007 139
2008 182
2009 206
2010 223
2011 234
2012 307
2013 268
2014 281
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2017 298
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5,844 results

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Page 1
Advances in the Drug Development and Quality Evaluation Principles of Oncolytic Herpes Simplex Virus.
Ghorab BEA, Liu T, Ying M, Wang P, Qin M, Xing J, Wang H, Xu F. Ghorab BEA, et al. Viruses. 2025 Apr 18;17(4):581. doi: 10.3390/v17040581. Viruses. 2025. PMID: 40285023 Review.
Oncolytic herpes simplex virus (oHSV) represents a promising therapeutic approach to treating cancers by virtue of its selective replication in and lysis of tumor cells, with stimulation of host antitumor immunity. ...Although much progress has been achieved, there is stil …
Oncolytic herpes simplex virus (oHSV) represents a promising therapeutic approach to treating cancers by virtue of its selective repl …
Small Genomes, Big Disruptions: Parvoviruses and the DNA Damage Response.
Abrahams RR, Majumder K. Abrahams RR, et al. Viruses. 2025 Mar 29;17(4):494. doi: 10.3390/v17040494. Viruses. 2025. PMID: 40284937 Review.
Parvoviruses are small, single-stranded DNA viruses that have evolved sophisticated mechanisms to hijack host cell machinery for replication and persistence. ...This review will explore the impact of parvovirus infections on host genome stability, focusing on key viral spe …
Parvoviruses are small, single-stranded DNA viruses that have evolved sophisticated mechanisms to hijack host cell machinery for repl …
Preclinical Efficacy and Safety of an Oncolytic Adenovirus KD01 for the Treatment of Bladder Cancer.
Guo J, Xiong S, Zhang X, Gong W, Si Y, Ma D, Li F, Han Y. Guo J, et al. Pharmaceuticals (Basel). 2025 Mar 31;18(4):511. doi: 10.3390/ph18040511. Pharmaceuticals (Basel). 2025. PMID: 40283946
Emerging clinical evidence has increasingly supported the therapeutic potential of oncolytic viruses in bladder cancer treatment. Based on this clinical foundation, we investigated the anti-tumor effects of KD01, a novel type 5 recombinant oncolytic adenoviru …
Emerging clinical evidence has increasingly supported the therapeutic potential of oncolytic viruses in bladder cancer treatme …
[The 16(th) Annual International Oncolytic Virotherapy Conference (IOVC) in Rotterdam: For the dreamers and doers of oncolytic virotherapy].
Olagnier D, Alain T. Olagnier D, et al. Virologie (Montrouge). 2025 Apr 25;29(3):0. doi: 10.1684/vir.2025.1084. Online ahead of print. Virologie (Montrouge). 2025. PMID: 40276892 French.
From October 27-30 2024, the 16th International Oncolytic Virotherapy Conference (IOVC) was held in Rotterdam, the Netherlands, a city that mirrors the spirit of resilience, conviction, and innovation of researchers in the field of oncolytic viruses. Rotterda …
From October 27-30 2024, the 16th International Oncolytic Virotherapy Conference (IOVC) was held in Rotterdam, the Netherlands, a cit …
IDH status dictates oHSV mediated metabolic reprogramming affecting anti-tumor immunity.
Sahu U, Mullarkey MP, Murphy SA, Anderson JC, Putluri V, Kamal AHM, Park JH, Lee TJ, Ling AL, Kaipparettu BA, Sharma A, Putluri N, Wenzel PL, Willey CD, Chiocca EA, Markert JM, Kaur B. Sahu U, et al. Nat Commun. 2025 Apr 24;16(1):3874. doi: 10.1038/s41467-025-58911-2. Nat Commun. 2025. PMID: 40274791 Free PMC article.
Identification of isocitrate dehydrogenase (IDH) mutations has uncovered the crucial role of metabolism in gliomagenesis. Oncolytic herpes virus (oHSV) initiates direct tumor debulking by tumor lysis and activates anti-tumor immunity, however, little is known about the rol …
Identification of isocitrate dehydrogenase (IDH) mutations has uncovered the crucial role of metabolism in gliomagenesis. Oncolytic h …
Gemcitabine: immunomodulatory or immunosuppressive role in the tumor microenvironment.
Nemati M, Hsu CY, Nathiya D, Kumar MR, Oghenemaro EF, Kariem M, Kaur P, Bhanot D, Hjazi A, Azam Saedi T. Nemati M, et al. Front Immunol. 2025 Apr 9;16:1536428. doi: 10.3389/fimmu.2025.1536428. eCollection 2025. Front Immunol. 2025. PMID: 40270972 Free PMC article. Review.
Furthermore, there is evidence that GEM enhances the therapeutic efficacy of immunotherapies, including oncolytic viruses, immune checkpoint inhibitors, CAR T-cells, and therapeutic vaccines. ...
Furthermore, there is evidence that GEM enhances the therapeutic efficacy of immunotherapies, including oncolytic viruses, imm …
Viral Vector-Based Cancer Vaccines.
Lundstrom K. Lundstrom K. Methods Mol Biol. 2025;2926:101-127. doi: 10.1007/978-1-0716-4542-0_9. Methods Mol Biol. 2025. PMID: 40266521
Viral vectors have been frequently used as vaccine-delivery vehicles. Both DNA and RNA viruses have been employed for vaccine development. Viral vectors based on adenoviruses (Ad), adeno-associated viruses (AAV), herpes simplex viruses (HSV), lentiviruses (LV …
Viral vectors have been frequently used as vaccine-delivery vehicles. Both DNA and RNA viruses have been employed for vaccine develop …
Nuclear Morphology-Based Assessment of Cell Fates Induced by a Microtubule Targeting Agent as a Single Treatment or Combined with an Oncolytic Virus.
De S, Ehrlich M. De S, et al. Methods Mol Biol. 2025;2926:91-100. doi: 10.1007/978-1-0716-4542-0_8. Methods Mol Biol. 2025. PMID: 40266520
When combined with imaging-based identification of cells expressing a nonstructural oncolytic virus protein, this approach enables the assessment of the potential for combined treatment with a microtubule targeting agent and an oncolytic virus (e.g., the Epizootic H …
When combined with imaging-based identification of cells expressing a nonstructural oncolytic virus protein, this approach enables th …
Current Landscape of Therapeutic Cancer Vaccines.
Rosenthal I, Padler-Karavani V. Rosenthal I, et al. Methods Mol Biol. 2025;2926:1-14. doi: 10.1007/978-1-0716-4542-0_1. Methods Mol Biol. 2025. PMID: 40266513 Review.
More recently, novel approaches for improving cancer vaccines have been explored, such as intratumoral vaccinations, oncolytic viruses, and combination immunotherapies. This chapter aims to provide a glimpse into some of the most common approaches for therapeutic ca …
More recently, novel approaches for improving cancer vaccines have been explored, such as intratumoral vaccinations, oncolytic vir …
Oncolytic Virus Infection Modulates Lysine Acetyltransferase in Gliomas: Comprehensive Analysis and Experimental Validation of KAT8 in Glioma.
Yin X, Hao Z, Liu Q, Ding R, Chen L, Jin M, Wang S. Yin X, et al. J Cell Mol Med. 2025 Apr;29(8):e70558. doi: 10.1111/jcmm.70558. J Cell Mol Med. 2025. PMID: 40259204 Free PMC article.
Oncolytic virotherapy, which uses engineered viruses to selectively target tumour cells, has emerged as a potential treatment in glioma. ...KAT8 was among the top 5 down-regulated genes in glioma cells after oncolytic viruses EV-A71 infection. KAT8 was …
Oncolytic virotherapy, which uses engineered viruses to selectively target tumour cells, has emerged as a potential treatment …
5,844 results

Searches related to "oncolytic viruses"