Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1999 1
2003 2
2005 1
2006 1
2007 2
2008 2
2009 5
2010 4
2011 3
2012 7
2013 11
2014 8
2015 12
2016 10
2017 9
2018 5
2019 7
2020 9
2021 13
2022 8
2023 9
2024 8
2025 7
2026 2

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

126 results

Results by year

Filters applied: . Clear all
Page 1
Opioids for refractory dyspnea.
Mahler DA. Mahler DA. Expert Rev Respir Med. 2013 Apr;7(2):123-34; quiz 135. doi: 10.1586/ers.13.5. Expert Rev Respir Med. 2013. PMID: 23547989 Review.
Both endogenous (beta-endorphin) and exogenous (morphine) opioids modulate the perception of dyspnea by binding to opioid receptors. Proposed mechanisms whereby opioids relieve refractory dyspnea include: decreasing respiratory drive with …
Both endogenous (beta-endorphin) and exogenous (morphine) opioids modulate the perception of dyspnea by binding to opioid …
Opioids in Treatment of Refractory Dyspnea in Chronic Obstructive Pulmonary Disease: Yes, No or Maybe.
Rajnoveanu RM, Harangus A, Todea DA, Man MA, Budin CE, Rajnoveanu AG. Rajnoveanu RM, et al. J Pers Med. 2024 Mar 19;14(3):318. doi: 10.3390/jpm14030318. J Pers Med. 2024. PMID: 38541060 Free PMC article. Review.
Breathlessness affects patients' quality of life, and despite various therapeutic strategies, the role of opioids in palliative care for COPD remains under investigation. The acceptance of a therapeutic trial of different types of opioids is increasing not only in e …
Breathlessness affects patients' quality of life, and despite various therapeutic strategies, the role of opioids in palliative care …
Opioids in patients with COPD and refractory dyspnea: literature review and design of a multicenter double blind study of low dosed morphine and fentanyl (MoreFoRCOPD).
van Dijk M, Mooren KJM, van den Berg JK, van Beurden-Moeskops WJC, Heller-Baan R, de Hosson SM, Lam-Wong WY, Peters L, Pool K, Kerstjens HAM. van Dijk M, et al. BMC Pulm Med. 2021 Sep 10;21(1):289. doi: 10.1186/s12890-021-01647-8. BMC Pulm Med. 2021. PMID: 34507574 Free PMC article. Review.
We searched for placebo-controlled randomized clinical trials investigating opioids for refractory dyspnea caused by COPD. We included trials reporting on dyspnea, health status and/or QoL. ...DISCUSSION: Evidence for opioids for refractory …
We searched for placebo-controlled randomized clinical trials investigating opioids for refractory dyspnea caused by CO …
Management of dyspnea in palliative care.
Crombeen AM, Lilly EJ. Crombeen AM, et al. Curr Oncol. 2020 Jun;27(3):142-145. doi: 10.3747/co.27.6413. Epub 2020 Jun 1. Curr Oncol. 2020. PMID: 32669923 Free PMC article.
Assessment of dyspnea is best accomplished by a subjective description; physiologic measures are only weakly correlated with the patient's experience. It is important to consider a wide range of possible malignant and nonmalignant causes of dyspnea in cancer patient …
Assessment of dyspnea is best accomplished by a subjective description; physiologic measures are only weakly correlated with the pati …
Opioids for palliation of refractory dyspnea in chronic obstructive pulmonary disease patients.
Varkey B. Varkey B. Curr Opin Pulm Med. 2010 Mar;16(2):150-4. doi: 10.1097/MCP.0b013e3283364378. Curr Opin Pulm Med. 2010. PMID: 20071992 Review.
The purpose of this article is to examine the efficacy of opioids administered orally, in nebulized form and other routes in dyspnea relief. Additionally, factors that inhibit the prescription of opioids and use of opioids are explored. ...One review o …
The purpose of this article is to examine the efficacy of opioids administered orally, in nebulized form and other routes in dyspn …
Opioids for treating refractory dyspnea in patients with heart failure: A protocol for systematic review and meta-analysis.
Lyu J, Sun X, Chen M, Li S. Lyu J, et al. Medicine (Baltimore). 2022 Nov 25;101(47):e31699. doi: 10.1097/MD.0000000000031699. Medicine (Baltimore). 2022. Retraction in: Medicine (Baltimore). 2023 Jul 7;102(27):e34401. doi: 10.1097/MD.0000000000034401. PMID: 36451406 Free PMC article. Retracted.
BACKGROUND: Dyspnea is a hallmark symptom of heart failure. The existing clinical studies have indicated that opioid can effectively improve the clinical symptoms of heart failure patients with dyspnea. ...RESULTS: This study will evaluate whether opioid …
BACKGROUND: Dyspnea is a hallmark symptom of heart failure. The existing clinical studies have indicated that opioid can effec …
[Refractory Dyspnea in Advanced COPD: Palliative Treatment with Opioids].
Ficker JH, Brückl WM. Ficker JH, et al. Pneumologie. 2019 Jul;73(7):430-438. doi: 10.1055/s-0043-103033. Epub 2019 Jul 10. Pneumologie. 2019. PMID: 31291670 Free article. German.
Non pharmacological therapies like pulmonary rehabilitation, long-term oxygen therapy or lung volume reduction can help to further improve dyspnea. Nevertheless, patients with advanced disease may develop refractory dyspnea. Randomized controlled trials demon …
Non pharmacological therapies like pulmonary rehabilitation, long-term oxygen therapy or lung volume reduction can help to further improve …
Attitudes toward opioids for refractory dyspnea in COPD among Dutch chest physicians.
Janssen DJ, de Hosson SM, bij de Vaate E, Mooren KJ, Baas AA. Janssen DJ, et al. Chron Respir Dis. 2015 May;12(2):85-92. doi: 10.1177/1479972315571926. Epub 2015 Feb 12. Chron Respir Dis. 2015. PMID: 25676931 Free article.
The aims of this study are to explore the attitudes of Dutch chest physicians toward prescription of opioids for refractory dyspnea to outpatients with advanced COPD and to investigate the barriers experienced by chest physicians toward opioid prescrip …
The aims of this study are to explore the attitudes of Dutch chest physicians toward prescription of opioids for refractory …
Pharmacologic Management of Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Clinical Practice Guideline.
Nici L, Mammen MJ, Charbek E, Alexander PE, Au DH, Boyd CM, Criner GJ, Donaldson GC, Dreher M, Fan VS, Gershon AS, Han MK, Krishnan JA, Martinez FJ, Meek PM, Morgan M, Polkey MI, Puhan MA, Sadatsafavi M, Sin DD, Washko GR, Wedzicha JA, Aaron SD. Nici L, et al. Am J Respir Crit Care Med. 2020 May 1;201(9):e56-e69. doi: 10.1164/rccm.202003-0625ST. Am J Respir Crit Care Med. 2020. PMID: 32283960 Free PMC article.
The evidence was appraised, rated, and graded, and recommendations were formulated using the Grading of Recommendations, Assessment, Development, and Evaluation approach.Results: After weighing the quality of evidence and balancing the desirable and undesirable effects, the guide …
The evidence was appraised, rated, and graded, and recommendations were formulated using the Grading of Recommendations, Assessment, Develop …
126 results