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1999 1
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87 results

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Page 1
How Periodontal Disease and Presence of Nitric Oxide Reducing Oral Bacteria Can Affect Blood Pressure.
Pignatelli P, Fabietti G, Ricci A, Piattelli A, Curia MC. Pignatelli P, et al. Int J Mol Sci. 2020 Oct 13;21(20):7538. doi: 10.3390/ijms21207538. Int J Mol Sci. 2020. PMID: 33066082 Free PMC article. Review.
Nitric oxide (NO), a small gaseous and multifunctional signaling molecule, is involved in the maintenance of metabolic and cardiovascular homeostasis. ...Nitrite is also derived from exogenous inorganic nitrate (NO(3)) contained in meat, vegetables, and drinking wat …
Nitric oxide (NO), a small gaseous and multifunctional signaling molecule, is involved in the maintenance of metabolic and car …
Oral Microbiome and Nitric Oxide: the Missing Link in the Management of Blood Pressure.
Bryan NS, Tribble G, Angelov N. Bryan NS, et al. Curr Hypertens Rep. 2017 Apr;19(4):33. doi: 10.1007/s11906-017-0725-2. Curr Hypertens Rep. 2017. PMID: 28353075 Review.
The presence or absence of select and specific bacteria may determine steady-state blood pressure levels. Eradication of oral bacteria through antiseptic mouthwash or overuse of antibiotics causes blood pressure to increase. Allowi …
The presence or absence of select and specific bacteria may determine steady-state blood pressure levels. Eradication o …
Dietary Nitrate and Nitric Oxide Metabolism: Mouth, Circulation, Skeletal Muscle, and Exercise Performance.
Jones AM, Vanhatalo A, Seals DR, Rossman MJ, Piknova B, Jonvik KL. Jones AM, et al. Med Sci Sports Exerc. 2021 Feb 1;53(2):280-294. doi: 10.1249/MSS.0000000000002470. Med Sci Sports Exerc. 2021. PMID: 32735111 Review.
Nitric oxide (NO) is a gaseous signaling molecule that plays an important role in myriad physiological processes, including the regulation of vascular tone, neurotransmission, mitochondrial respiration, and skeletal muscle contractile function. ...It has been report …
Nitric oxide (NO) is a gaseous signaling molecule that plays an important role in myriad physiological processes, including th …
Oral nitrate-reducing bacteria as potential probiotics for blood pressure homeostasis.
Chai X, Liu L, Chen F. Chai X, et al. Front Cardiovasc Med. 2024 Apr 4;11:1337281. doi: 10.3389/fcvm.2024.1337281. eCollection 2024. Front Cardiovasc Med. 2024. PMID: 38638884 Free PMC article. Review.
In this review, we explore the role of oral microbiota in maintaining blood pressure homeostasis, particularly the connection between nitrate-reducing bacteria and the bioavailability of NO in the bloodstream and blood pressure changes. T …
In this review, we explore the role of oral microbiota in maintaining blood pressure homeostasis, particularly the conn …
Nitrate-responsive oral microbiome modulates nitric oxide homeostasis and blood pressure in humans.
Vanhatalo A, Blackwell JR, L'Heureux JE, Williams DW, Smith A, van der Giezen M, Winyard PG, Kelly J, Jones AM. Vanhatalo A, et al. Free Radic Biol Med. 2018 Aug 20;124:21-30. doi: 10.1016/j.freeradbiomed.2018.05.078. Epub 2018 May 25. Free Radic Biol Med. 2018. PMID: 29807159 Free PMC article. Clinical Trial.
A possible mechanism linking the oral microbiota to health is the nitrate (NO(3)(-))-nitrite (NO(2)(-))-nitric oxide (NO) pathway, which relies on oral bacteria to reduce NO(3)(-) to NO(2)(-). NO (generated from both NO(2)(-) and L-arginine) reg …
A possible mechanism linking the oral microbiota to health is the nitrate (NO(3)(-))-nitrite (NO(2)(-))-nitric oxide (N …
The oral microbiome, nitric oxide and exercise performance.
Bryan NS, Burleigh MC, Easton C. Bryan NS, et al. Nitric Oxide. 2022 Aug 1;125-126:23-30. doi: 10.1016/j.niox.2022.05.004. Epub 2022 May 28. Nitric Oxide. 2022. PMID: 35636654 Free article. Review.
There is unequivocal evidence that dysbiosis (e.g. through disease) or disruption (e.g. by use of antiseptic mouthwash or antibiotics) of the oral microbiota will suppress nitric oxide production via the nitrate-nitrite-nitric oxide pathway and …
There is unequivocal evidence that dysbiosis (e.g. through disease) or disruption (e.g. by use of antiseptic mouthwash or antibiotics) of th …
Pathways Linking Oral Bacteria, Nitric Oxide Metabolism, and Health.
Morou-Bermúdez E, Torres-Colón JE, Bermúdez NS, Patel RP, Joshipura KJ. Morou-Bermúdez E, et al. J Dent Res. 2022 Jun;101(6):623-631. doi: 10.1177/00220345211064571. Epub 2022 Jan 26. J Dent Res. 2022. PMID: 35081826 Free PMC article.
Nitrate-reducing oral bacteria have gained a lot of interest due to their involvement in nitric oxide (NO) synthesis and its important cardiometabolic outcomes. ...Based on this information, a novel behavioral and microbial model for nitric o …
Nitrate-reducing oral bacteria have gained a lot of interest due to their involvement in nitric oxide (NO) synth …
Current clinical framework on nitric oxide role in periodontal disease and blood pressure.
Lima L, Gaspar S, Rocha BS, Alves R, Almeida MG. Lima L, et al. Clin Oral Investig. 2024 Sep 12;28(10):521. doi: 10.1007/s00784-024-05913-x. Clin Oral Investig. 2024. PMID: 39264471 Free PMC article. Review.
RESULTS: A nitrate-rich diet increases nitrate and nitrite levels in saliva and plasma, promoting oral health by favorably altering the oral microbiome. Chlorhexidine (CHX) mouthrinses disrupt the nitrate-nitrite-NO pathway, reducing NO bioavailability, and potentia …
RESULTS: A nitrate-rich diet increases nitrate and nitrite levels in saliva and plasma, promoting oral health by favorably altering t …
I. Arginine.
Tapiero H, Mathé G, Couvreur P, Tew KD. Tapiero H, et al. Biomed Pharmacother. 2002 Nov;56(9):439-45. doi: 10.1016/s0753-3322(02)00284-6. Biomed Pharmacother. 2002. PMID: 12481980 Review.
It reduces blood pressure and renal vascular resistance in essential hypertensive patients with normal or insufficient renal function. ...The main importance of Arg is attributed to its role as a precursor for the synthesis of nitric oxide (NO), a free …
It reduces blood pressure and renal vascular resistance in essential hypertensive patients with normal or insufficient renal f …
Ageing modifies the oral microbiome, nitric oxide bioavailability and vascular responses to dietary nitrate supplementation.
Vanhatalo A, L'Heureux JE, Black MI, Blackwell JR, Aizawa K, Thompson C, Williams DW, van der Giezen M, Winyard PG, Jones AM. Vanhatalo A, et al. Free Radic Biol Med. 2025 Oct;238:682-696. doi: 10.1016/j.freeradbiomed.2025.07.002. Epub 2025 Jul 3. Free Radic Biol Med. 2025. PMID: 40615058 Free article. Clinical Trial.

This study evaluated whether changes in the oral microbiome in response to dietary nitrate and antiseptic mouthwash treatments were related to changes in nitric oxide bioavailability and vascular function. ...SY095 r = -0.81, P < 0.0001). Greater blood

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This study evaluated whether changes in the oral microbiome in response to dietary nitrate and antiseptic mouthwash treatments were r …
87 results