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39 results

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Diagnostic and therapeutic use of oral micronized progesterone in endocrinology.
Memi E, Pavli P, Papagianni M, Vrachnis N, Mastorakos G. Memi E, et al. Rev Endocr Metab Disord. 2024 Aug;25(4):751-772. doi: 10.1007/s11154-024-09882-0. Epub 2024 Apr 23. Rev Endocr Metab Disord. 2024. PMID: 38652231 Free PMC article. Review.
In addition, it exerts numerous effects on other endocrine systems. Micronized progesterone (MP) is natural progesterone with increased bioavailability, due to its pharmacotechnical micronized structure, which makes it an attractive diagnostic and therapeutic tool. …
In addition, it exerts numerous effects on other endocrine systems. Micronized progesterone (MP) is natural progesterone with …
Oral micronized progesterone for perimenopausal night sweats and hot flushes a Phase III Canada-wide randomized placebo-controlled 4 month trial.
Prior JC, Cameron A, Fung M, Hitchcock CL, Janssen P, Lee T, Singer J. Prior JC, et al. Sci Rep. 2023 Jun 5;13(1):9082. doi: 10.1038/s41598-023-35826-w. Sci Rep. 2023. PMID: 37277418 Free PMC article. Clinical Trial.
It was a double-blind, randomized trial of 300 mg oral micronized progesterone@bedtime versus placebo for 3-months (m) after a 1-m untreated baseline during 2012/1-2017/4. ...However, the 95% CI [- 3.97, 0.95] P = 0.222, did not exclude 3, a minimal clinically impor …
It was a double-blind, randomized trial of 300 mg oral micronized progesterone@bedtime versus placebo for 3-months (m) after a …
Improvement in sleep outcomes with a 17beta-estradiol-progesterone oral capsule (TX-001HR) for postmenopausal women.
Kagan R, Constantine G, Kaunitz AM, Bernick B, Mirkin S. Kagan R, et al. Menopause. 2018 Dec 21;26(6):622-628. doi: 10.1097/GME.0000000000001278. Menopause. 2018. PMID: 30586005 Free PMC article. Clinical Trial.
OBJECTIVE: The aim of the study was to evaluate the effects of TX-001HR, a single-capsule 17beta-estradiol-progesterone on sleep parameters in postmenopausal women with vasomotor symptoms (VMS) using the Medical Outcomes Study (MOS)-Sleep scale questionnaire …
OBJECTIVE: The aim of the study was to evaluate the effects of TX-001HR, a single-capsule 17beta-estradiol-progesterone on sleep …
A combined, bioidentical, oral, 17beta-estradiol and progesterone capsule for the treatment of moderate to severe vasomotor symptoms due to menopause.
Archer DF, Bernick BA, Mirkin S. Archer DF, et al. Expert Rev Clin Pharmacol. 2019 Aug;12(8):729-739. doi: 10.1080/17512433.2019.1637731. Epub 2019 Jul 22. Expert Rev Clin Pharmacol. 2019. PMID: 31282768 Free article. Review.
Introduction: Many women seek treatment to alleviate menopausal vasomotor symptoms (VMS). Numerous women use combination compounded hormone therapy (CHT) to achieve the benefits of estrogen/progesterone for endometrial protection. ...Rates of amenorrhea were high an …
Introduction: Many women seek treatment to alleviate menopausal vasomotor symptoms (VMS). Numerous women use combination compounded h …
Sleep in women across the life cycle from adulthood through menopause.
Moline ML, Broch L, Zak R, Gross V. Moline ML, et al. Sleep Med Rev. 2003 Apr;7(2):155-77. doi: 10.1053/smrv.2001.0228. Sleep Med Rev. 2003. PMID: 12628216 Review.
As a result, definitive conclusions about the impact of the menstrual cycle and use of oral contraceptives on sleep parameters cannot yet be made. Sleep disruption during pregnancy and postpartum is nearly universal, but effective and practical countermeasure …
As a result, definitive conclusions about the impact of the menstrual cycle and use of oral contraceptives on sleep parameters …
Changes in Sleep Quality after Hormone Replacement Therapy with Micronized Progesterone in Japanese Menopausal Women: A Pilot Study.
Ogawa M, Makita K, Takamatsu K, Takahashi T. Ogawa M, et al. J Menopausal Med. 2025 Apr;31(1):45-50. doi: 10.6118/jmm.24030. J Menopausal Med. 2025. PMID: 40347165 Free PMC article.
Sleep disturbances are common among women during menopause. Hormone replacement therapy (HRT) using micronized progesterone (MP) may improve sleep, owing to its neurosteroid effects. ...We conducted a single-arm, open-label study to examine the effects …
Sleep disturbances are common among women during menopause. Hormone replacement therapy (HRT) using micronized progesterone …
Relationship between vasomotor symptom improvements and quality of life and sleep outcomes in menopausal women treated with oral, combined 17beta-estradiol/progesterone.
Mirkin S, Graham S, Revicki DA, Bender RH, Bernick B, Constantine GD. Mirkin S, et al. Menopause. 2019 Jan 9;26(6):637-642. doi: 10.1097/GME.0000000000001294. Menopause. 2019. PMID: 30601452 Free PMC article. Clinical Trial.
OBJECTIVE: To characterize the impact of TX-001HR on the relationship between vasomotor symptom (VMS) improvement and quality of life and sleep. METHODS: REPLENISH (NCT01942668) was a phase 3, randomized, double-blind, placebo-controlled, multicenter trial, which evaluated …
OBJECTIVE: To characterize the impact of TX-001HR on the relationship between vasomotor symptom (VMS) improvement and quality of life and …
Sleep after intranasal progesterone vs. zolpidem and placebo in postmenopausal women - A randomized, double-blind cross over study.
Schüssler P, Kluge M, Adamczyk M, Beitinger ME, Beitinger P, Bleifuss A, Cordeiro S, Mattern C, Uhr M, Wetter TC, Yassouridis A, Rupprecht R, Friess E, Steiger A. Schüssler P, et al. Psychoneuroendocrinology. 2018 Jun;92:81-86. doi: 10.1016/j.psyneuen.2018.04.001. Epub 2018 Apr 4. Psychoneuroendocrinology. 2018. PMID: 29649764 Clinical Trial.
CONTEXT: The loss of progesterone during menopause is linked to sleep complaints of the affected women. Previously we demonstrated sleep promoting effects of oral progesterone replacement in postmenopausal women. ...CONCLUSIONS: Our study …
CONTEXT: The loss of progesterone during menopause is linked to sleep complaints of the affected women. Previously we d …
Impact of progesterone on skin and hair in menopause - a comprehensive review.
Gasser S, Heidemeyer K, von Wolff M, Stute P. Gasser S, et al. Climacteric. 2021 Jun;24(3):229-235. doi: 10.1080/13697137.2020.1838476. Epub 2021 Feb 2. Climacteric. 2021. PMID: 33527841 Review.
In clinical practice, micronized progesterone (MP) is frequently recommended to treat signs and symptoms of skin and hair aging in menopausal women. ...In menopausal women, MHT displays beneficial effects on skin aging. There is poor quality but promising sci …
In clinical practice, micronized progesterone (MP) is frequently recommended to treat signs and symptoms of skin and hair aging in …
Progesterone for treatment of symptomatic menopausal women.
Prior JC. Prior JC. Climacteric. 2018 Aug;21(4):358-365. doi: 10.1080/13697137.2018.1472567. Epub 2018 Jul 2. Climacteric. 2018. PMID: 29962247 Free article. Review.
This review's purpose is to highlight evidence that oral micronized progesterone (progesterone) is effective for hot flushes and night sweats (vasomotor symptoms, VMS), improves sleep and is likely safe in menopausal women (who are more than 1 y …
This review's purpose is to highlight evidence that oral micronized progesterone (progesterone) is effective for hot fl …
39 results