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1950 4
1951 2
1952 3
1953 4
1954 1
1955 2
1956 5
1957 1
1958 3
1959 3
1960 5
1962 1
1963 5
1964 8
1965 7
1966 4
1967 8
1968 3
1969 11
1970 8
1971 14
1972 18
1973 14
1974 10
1975 38
1976 44
1977 43
1978 48
1979 38
1980 47
1981 62
1982 82
1983 84
1984 86
1985 121
1986 135
1987 159
1988 150
1989 220
1990 224
1991 223
1992 266
1993 292
1994 351
1995 424
1996 500
1997 555
1998 676
1999 735
2000 919
2001 948
2002 1056
2003 1197
2004 1511
2005 1730
2006 1976
2007 2363
2008 2468
2009 2634
2010 2959
2011 3222
2012 3629
2013 4163
2014 4380
2015 4589
2016 4507
2017 4672
2018 4905
2019 4911
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2023 4740
2024 4843
2025 5487
2026 2959

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83,936 results

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Page 1
What constitutes the prefrontal cortex?
Carlén M. Carlén M. Science. 2017 Oct 27;358(6362):478-482. doi: 10.1126/science.aan8868. Science. 2017. PMID: 29074767 Review.
An important goal is to reveal how the prefrontal cortex enables complex behavior. However, the prefrontal cortex still lacks a conclusive definition. The structure and function of this brain area across species remain unresolved. This state of …
An important goal is to reveal how the prefrontal cortex enables complex behavior. However, the prefrontal cortex …
Medial prefrontal cortex in neurological diseases.
Xu P, Chen A, Li Y, Xing X, Lu H. Xu P, et al. Physiol Genomics. 2019 Sep 1;51(9):432-442. doi: 10.1152/physiolgenomics.00006.2019. Epub 2019 Aug 2. Physiol Genomics. 2019. PMID: 31373533 Free PMC article. Review.
The medial prefrontal cortex (mPFC) is a crucial cortical region that integrates information from numerous cortical and subcortical areas and converges updated information to output structures. ...
The medial prefrontal cortex (mPFC) is a crucial cortical region that integrates information from numerous cortical and subcor …
The mouse prefrontal cortex: Unity in diversity.
Le Merre P, Ährlund-Richter S, Carlén M. Le Merre P, et al. Neuron. 2021 Jun 16;109(12):1925-1944. doi: 10.1016/j.neuron.2021.03.035. Epub 2021 Apr 23. Neuron. 2021. PMID: 33894133 Free article. Review.
The prefrontal cortex (PFC) is considered to constitute the highest stage of neural integration and to be devoted to representation and production of actions. ...We foresee that data-rich mouse studies will be key to shed light on the general prefrontal archi …
The prefrontal cortex (PFC) is considered to constitute the highest stage of neural integration and to be devoted to represent …
Amygdala, medial prefrontal cortex, and hippocampal function in PTSD.
Shin LM, Rauch SL, Pitman RK. Shin LM, et al. Ann N Y Acad Sci. 2006 Jul;1071:67-79. doi: 10.1196/annals.1364.007. Ann N Y Acad Sci. 2006. PMID: 16891563 Review.
Importantly, amygdala responsivity is positively associated with symptom severity in PTSD. In contrast, medial prefrontal cortex appears to be volumetrically smaller and is hyporesponsive during symptomatic states and the performance of emotional cognitive tasks in …
Importantly, amygdala responsivity is positively associated with symptom severity in PTSD. In contrast, medial prefrontal cortex …
Prefrontal cortex.
Chafee MV, Heilbronner SR. Chafee MV, et al. Curr Biol. 2022 Apr 25;32(8):R346-R351. doi: 10.1016/j.cub.2022.02.071. Curr Biol. 2022. PMID: 35472417 Free PMC article.
Perhaps the least controversial feature of the prefrontal cortex is its complexity. The prefrontal cortex is anatomically, functionally, and computationally complex. ...Perhaps as a result, prefrontal cortex is also computationally comple …
Perhaps the least controversial feature of the prefrontal cortex is its complexity. The prefrontal cortex is ana …
Orbitofrontal cortex.
Rudebeck PH, Rich EL. Rudebeck PH, et al. Curr Biol. 2018 Sep 24;28(18):R1083-R1088. doi: 10.1016/j.cub.2018.07.018. Curr Biol. 2018. PMID: 30253144 Free PMC article.
The orbitofrontal cortex is a large and heterogeneous cortical area on the ventral surface of the frontal lobe and is intimately involved in emotion and executive function. In this Primer, Peter Rudebeck and Erin Rich summarize our understanding of the mechanisms th …
The orbitofrontal cortex is a large and heterogeneous cortical area on the ventral surface of the frontal lobe and is intimate …
Primary ciliary protein kinase A activity in the prefrontal cortex modulates stress in mice.
Yang J, Dong Y, Liu J, Peng Y, Wang D, Li L, Hu X, Li J, Wang L, Chu J, Ma J, Shi H, Shi SH. Yang J, et al. Neuron. 2025 Apr 16;113(8):1276-1289.e5. doi: 10.1016/j.neuron.2025.02.002. Epub 2025 Mar 7. Neuron. 2025. PMID: 40056898
Here, we show that, in response to various animal stressors, primary cilia in the mouse prefrontal cortex (PFC) exhibit consistent axonemal elongation. Selective removal of excitatory neuron primary cilia in the prefrontal but not sensory cortex leads …
Here, we show that, in response to various animal stressors, primary cilia in the mouse prefrontal cortex (PFC) exhibit consis …
Chronic stress-induced neuroplasticity in the prefrontal cortex: Structural, functional, and molecular mechanisms from development to aging.
Algaidi SA. Algaidi SA. Brain Res. 2025 Mar 15;1851:149461. doi: 10.1016/j.brainres.2025.149461. Epub 2025 Jan 27. Brain Res. 2025. PMID: 39864644 Review.
Chronic stress profoundly affects the structure and function of the prefrontal cortex (PFC), a brain region critical for executive functions and emotional regulation. ...
Chronic stress profoundly affects the structure and function of the prefrontal cortex (PFC), a brain region critical for execu …
Characterization of dopaminergic projections from the ventral tegmental area and the dorsal raphe nucleus to the orbital frontal cortex.
Noble DJ, Mohammadkhani A, Qiao M, Borgland SL. Noble DJ, et al. Eur J Neurosci. 2024 Apr;59(7):1460-1479. doi: 10.1111/ejn.16230. Epub 2023 Dec 28. Eur J Neurosci. 2024. PMID: 38155094
The orbitofrontal cortex (OFC) is a key node in the cortico-limbic-striatal circuitry that influences decision-making guided by the relative value of outcomes. Midbrain dopamine from either the ventral tegmental area (VTA) or the dorsal raphe nucleus (DRN) has the p …
The orbitofrontal cortex (OFC) is a key node in the cortico-limbic-striatal circuitry that influences decision-making guided by the r …
Prefrontal ErbB4-positive interneurons for avoidance.
Cui W, Shen C, Xiong WC, Mei L. Cui W, et al. Cell Rep. 2025 May 27;44(5):115628. doi: 10.1016/j.celrep.2025.115628. Epub 2025 Apr 30. Cell Rep. 2025. PMID: 40310724 Free article.
Avoidance is a major behavior for survival. The prefrontal cortex (PFC) is known to be involved in approach-avoidance decision-making, but how PFC interneurons (INs) collaborate with excitatory neurons in this process remains unclear. ...
Avoidance is a major behavior for survival. The prefrontal cortex (PFC) is known to be involved in approach-avoidance decision …
83,936 results
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