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Radiogenomic profiling of prostate tumors prior to external beam radiotherapy converges on a transcriptomic signature of TGF-β activity driving tumor recurrence.
Ku AT, Shankavaram U, Trostel SY, Zhang H, Kartal S, Sater HA, Harmon SA, Carrabba NV, Liu Y, Ryu H, Proudfoot JA, Hong BH, Wood BJ, Pinto PA, Choyke PL, Roach M, Sandler HM, Pugh SL, Zeitzer KL, Mendez LC, Kapadia NS, Hall WA, Desai AB, Stoyanova RS, Pollack A, Davicioni E, Chua MLK, Turkbey B, Sowalsky AG, Citrin DE. Ku AT, et al. Clin Cancer Res. 2025 Oct 2. doi: 10.1158/1078-0432.CCR-25-2186. Online ahead of print. Clin Cancer Res. 2025. PMID: 41037000