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7,155 results

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Page 1
Organ-on-a-chip meets artificial intelligence in drug evaluation.
Deng S, Li C, Cao J, Cui Z, Du J, Fu Z, Yang H, Chen P. Deng S, et al. Theranostics. 2023 Aug 15;13(13):4526-4558. doi: 10.7150/thno.87266. eCollection 2023. Theranostics. 2023. PMID: 37649608 Free PMC article. Review.
However, animal welfare protection and other shortcomings of traditional drug development models pose obstacles and challenges to drug evaluation. Organ-on-a-chip (OoC) technology, which simulates human organs on a chip of the physiological environment …
However, animal welfare protection and other shortcomings of traditional drug development models pose obstacles and challenges to drug evalu …
Organ-on-a-Chip: A New Paradigm for Drug Development.
Ma C, Peng Y, Li H, Chen W. Ma C, et al. Trends Pharmacol Sci. 2021 Feb;42(2):119-133. doi: 10.1016/j.tips.2020.11.009. Epub 2020 Dec 16. Trends Pharmacol Sci. 2021. PMID: 33341248 Free PMC article. Review.
The pharmaceutical industry has been desperately searching for efficient drug discovery methods. Organ-on-a-Chip, a cutting-edge technology that can emulate the physiological environment and functionality of human organs on a chip for disease modeling …
The pharmaceutical industry has been desperately searching for efficient drug discovery methods. Organ-on-a-Chip, a cutting-ed …
A Comprehensive Review of Organ-on-a-Chip Technology and Its Applications.
Farhang Doost N, Srivastava SK. Farhang Doost N, et al. Biosensors (Basel). 2024 May 1;14(5):225. doi: 10.3390/bios14050225. Biosensors (Basel). 2024. PMID: 38785699 Free PMC article. Review.
Organ-on-a-chip (OOC) is an emerging technology that simulates an artificial organ within a microfluidic cell culture chip. ...Current technological expansions involve multiple organ microenvironments on a single chip, allowing for studyi …
Organ-on-a-chip (OOC) is an emerging technology that simulates an artificial organ within a microfluidic cell culture …
Organ-on-chip technology: Opportunities and challenges.
Srivastava SK, Foo GW, Aggarwal N, Chang MW. Srivastava SK, et al. Biotechnol Notes. 2024 Jan 5;5:8-12. doi: 10.1016/j.biotno.2024.01.001. eCollection 2024. Biotechnol Notes. 2024. PMID: 39416695 Free PMC article. Review.
Organ-on-chip (OOC) technology is an innovative approach that reproduces human organ structures and functions on microfluidic platforms, offering detailed insights into intricate physiological processes. ...
Organ-on-chip (OOC) technology is an innovative approach that reproduces human organ structures and functions on microf …
Organ-On-A-Chip Devices: Technology Progress and Challenges.
Obeid PJ, Yammine P, El-Nakat H, Kassab R, Tannous T, Nasr Z, Maarawi T, Dahdah N, El Safadi A, Mansour A, Chmayssem A. Obeid PJ, et al. Chembiochem. 2024 Dec 2;25(23):e202400580. doi: 10.1002/cbic.202400580. Epub 2024 Oct 23. Chembiochem. 2024. PMID: 39183173 Review.
Organ-On-a-Chip (OOC) is a multichannel 3D-microfluidic cell-culture system incorporated in a chip that simulates the behavior of an organ. ...It predicts not only the effects of drugs on the target organs but also, using body-on-a-chip s …
Organ-On-a-Chip (OOC) is a multichannel 3D-microfluidic cell-culture system incorporated in a chip that simulates the b …
Organ-on-a-chip: future of female reproductive pathophysiological models.
Deng ZM, Dai FF, Wang RQ, Deng HB, Yin TL, Cheng YX, Chen GT. Deng ZM, et al. J Nanobiotechnology. 2024 Jul 31;22(1):455. doi: 10.1186/s12951-024-02651-w. J Nanobiotechnology. 2024. PMID: 39085921 Free PMC article. Review.
This technology can not only reconstruct the organ structure but also emulate the organ function as much as possible. The precisely controlled fluidic microenvironment provided by microfluidics vividly mimics the complex endocrine hormone crosstalk among various …
This technology can not only reconstruct the organ structure but also emulate the organ function as much as possible. The prec …
Engineering Organ-on-a-Chip to Accelerate Translational Research.
Ko J, Park D, Lee S, Gumuscu B, Jeon NL. Ko J, et al. Micromachines (Basel). 2022 Jul 28;13(8):1200. doi: 10.3390/mi13081200. Micromachines (Basel). 2022. PMID: 36014122 Free PMC article. Review.
We guide the use of organ-on-chip technology in tissue engineering applications. Organ-on-chip technology is a form of microengineered cell culture platform that elaborates the in-vivo like organ or tissue microenvironments. The organ-on- …
We guide the use of organ-on-chip technology in tissue engineering applications. Organ-on-chip technology is a f …
Organ-on-chip systems as a model for nanomedicine.
Stavrou M, Phung N, Grimm J, Andreou C. Stavrou M, et al. Nanoscale. 2023 Jun 15;15(23):9927-9940. doi: 10.1039/d3nr01661g. Nanoscale. 2023. PMID: 37254663 Free PMC article. Review.
In this review, we report studies that used organ-on-chip approaches to study the interactions of NPs with biological systems. We present examples of NP toxicity studies, studies using biological NPs such as viruses, as well as modeling biological barriers and cance …
In this review, we report studies that used organ-on-chip approaches to study the interactions of NPs with biological systems. …
Organ-on-a-Chip systems for new drugs development.
Vargas R, Egurbide-Sifre A, Medina L. Vargas R, et al. ADMET DMPK. 2021 Mar 22;9(2):111-141. doi: 10.5599/admet.942. eCollection 2021. ADMET DMPK. 2021. PMID: 35299767 Free PMC article. Review.
Research on alternatives to the use of animal models and cell cultures has led to the creation of organ-on-a-chip systems, in which organs and their physiological reactions to the presence of external stimuli are simulated. These systems could even replace th …
Research on alternatives to the use of animal models and cell cultures has led to the creation of organ-on-a-chip systems, in …
Organ-On-A-Chip Database Revealed-Achieving the Human Avatar in Silicon.
Jiang L, Li Q, Liang W, Du X, Yang Y, Zhang Z, Xu L, Zhang J, Li J, Chen Z, Gu Z. Jiang L, et al. Bioengineering (Basel). 2022 Nov 12;9(11):685. doi: 10.3390/bioengineering9110685. Bioengineering (Basel). 2022. PMID: 36421086 Free PMC article. Review.
Organ-on-a-chip (OOC) provides microphysiological conditions on a microfluidic chip, which makes up for the shortcomings of traditional in vitro cellular culture models and animal models. ...We used examples to overview how the BAP database has contributed to …
Organ-on-a-chip (OOC) provides microphysiological conditions on a microfluidic chip, which makes up for the shortcoming …
7,155 results