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Year Number of Results
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1992 3
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68 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Pharmacokinetics and safety of injected ornidazole compared to its enantiomer levornidazole in healthy Chinese subjects.
Liu Y, Zhang Y, Xue W, Wang J, Bai W, Wang T, Liu Y, Tang K, Qin J, Li K, Wang X. Liu Y, et al. Int J Clin Pharmacol Ther. 2023 Dec;61(12):543-550. doi: 10.5414/CP204442. Int J Clin Pharmacol Ther. 2023. PMID: 37840522 Clinical Trial.
Subjects received an intravenous injection of either levornidazole sodium chloride injection (200 mL: 0.5 g) or ornidazole sodium chloride injection (200 mL: 0.5 g) once per period. The plasma concentrations of levornidazole, ornidazole, and their metabolites were m …
Subjects received an intravenous injection of either levornidazole sodium chloride injection (200 mL: 0.5 g) or ornidazole sodium chl …
Randomized multicenter trial comparing minocycline and ornidazole with classical quadruple therapy in Helicobacter pylori treatment.
Lin Y, Lin X, Suo B, Chen Q, Cheng X, Lin Z, Huang X. Lin Y, et al. Sci Rep. 2025 May 10;15(1):16318. doi: 10.1038/s41598-025-01117-9. Sci Rep. 2025. PMID: 40348820 Free PMC article. Clinical Trial.
This study evaluated the efficacy, safety, and cost of minocycline, ornidazole, esomeprazole, and bismuth (MOEB) therapy versus classical therapy (amoxicillin, clarithromycin, esomeprazole, and bismuth potassium citrate, ACEB) for Helicobacter pylori eradication. ...
This study evaluated the efficacy, safety, and cost of minocycline, ornidazole, esomeprazole, and bismuth (MOEB) therapy versus class …
Evaluation of Ornidazole Tablets Bioequivalence in Chinese Healthy Participants Under Fasted and Fed Conditions Using Pharmacokinetic Parameters.
Wang Y, He Y, Li W, Li H, Tang L, Dai X, Pei Y, Gao L. Wang Y, et al. Drugs R D. 2024 Jun;24(2):145-154. doi: 10.1007/s40268-024-00457-7. Epub 2024 Apr 22. Drugs R D. 2024. PMID: 38644462 Free PMC article. Clinical Trial.
BACKGROUND AND OBJECTIVE: Ornidazole, the third generation of nitroimidazole derivatives after metronidazole and tinidazole, it exerts both bactericidal and antiprotozoal effects. The purpose of this study was to evaluate the pharmacokinetic and bioequivalence of two or …
BACKGROUND AND OBJECTIVE: Ornidazole, the third generation of nitroimidazole derivatives after metronidazole and tinidazole, it exert …
Ornidazole for prophylaxis of postoperative Crohn's disease recurrence: a randomized, double-blind, placebo-controlled trial.
Rutgeerts P, Van Assche G, Vermeire S, D'Haens G, Baert F, Noman M, Aerden I, De Hertogh G, Geboes K, Hiele M, D'Hoore A, Penninckx F. Rutgeerts P, et al. Gastroenterology. 2005 Apr;128(4):856-61. doi: 10.1053/j.gastro.2005.01.010. Gastroenterology. 2005. PMID: 15825069 Clinical Trial.
Secondary end points were endoscopic recurrence at 3 months and 12 months after resection. RESULTS: Two patients in the ornidazole group withdrew consent and were not dosed. Ornidazole significantly reduced the clinical recurrence rate at 1 year from 15 of 40 (37.5% …
Secondary end points were endoscopic recurrence at 3 months and 12 months after resection. RESULTS: Two patients in the ornidazole gr …
Ornidazole compared to phenoxymethylpenicillin in the treatment of orofacial infections.
von Konow L, Nord CE. von Konow L, et al. J Antimicrob Chemother. 1983 Mar;11(3):207-15. doi: 10.1093/jac/11.3.207. J Antimicrob Chemother. 1983. PMID: 6404880 Clinical Trial.
A double blind, randomized study comprising 60 patients was undertaken to compare the efficacy of ornidazole to that of phenoxymethylpenicillin in the treatment of orofacial infections. Thirty patients received ornidazole 500 mg orally every 12 h for seven days and …
A double blind, randomized study comprising 60 patients was undertaken to compare the efficacy of ornidazole to that of phenoxymethyl …
A comparison of metronidazole and single-dose ornidazole for the treatment of dientamoebiasis.
Kurt O, Girginkardeşler N, Balcioğlu IC, Ozbilgin A, Ok UZ. Kurt O, et al. Clin Microbiol Infect. 2008 Jun;14(6):601-4. doi: 10.1111/j.1469-0691.2008.02002.x. Epub 2008 Apr 5. Clin Microbiol Infect. 2008. PMID: 18397330 Free article. Clinical Trial.
This study compared the efficacies of metronidazole and ornidazole in a group of 112 patients with dientamoebiasis. Patients were randomised into two treatment groups: group 1 (n = 56) received metronidazole for 5 days, 20 mg/kg/day for children and 1.5 g/day for adults, i …
This study compared the efficacies of metronidazole and ornidazole in a group of 112 patients with dientamoebiasis. Patients were ran …
Efficacy and safety of different drugs for the treatment of bacterial vaginosis: a systematic review and network meta-analysis.
Fan Y, Gu Y, Xian Y, Li Q, He Y, Chen K, Yu H, Deng H, Xiong L, Cui Z, Yang Y, Xiang Y. Fan Y, et al. Front Cell Infect Microbiol. 2024 Oct 11;14:1402346. doi: 10.3389/fcimb.2024.1402346. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 39463760 Free PMC article.
Direct meta-analysis results showed that ornidazole had a better clinical cure rate than Secnidazole (RR 1.22; 95%-CI 1.10-1.34), oral ornidazole had a better clinical cure rate than Secnidazole (RR 1.23; 95%-CI 1.11-1.36). ...CONCLUSIONS: The results of this system …
Direct meta-analysis results showed that ornidazole had a better clinical cure rate than Secnidazole (RR 1.22; 95%-CI 1.10-1.34), ora …
Use of ornidazole in fractionated radiotherapy: dose tolerance, serum and tumour tissue concentration.
Okkan S, Yazici Z, Uzel R, Akçasu A, Turkan S, Hacibekiroğlu M, Olgun P, Egehan I. Okkan S, et al. Radiother Oncol. 1986 Apr;5(4):295-301. doi: 10.1016/s0167-8140(86)80178-5. Radiother Oncol. 1986. PMID: 3523636 Clinical Trial.
Ornidazole or placebo were given orally, two times weekly, for 3 weeks. Dose was 2.5 g/m2 for each administration. ...No important side effect was observed in men receiving ornidazole. Serum concentration of ornidazole reached the maximum level in 2-4 h after …
Ornidazole or placebo were given orally, two times weekly, for 3 weeks. Dose was 2.5 g/m2 for each administration. ...No important si …
Ornidazole-based sequential therapy is not effective in Helicobacter pylori eradication in children.
Baysoy G, Saltık Temızel İN, Uslu N, Balamtekın N, Demır H, Gürkan F, Özen H, Akyön Y, Yüce A. Baysoy G, et al. Turk J Gastroenterol. 2013;24(5):382-6. doi: 10.4318/tjg.2013.0575. Turk J Gastroenterol. 2013. PMID: 24557960 Free article. Clinical Trial.
The aim of this study is to compare the ornidazole-based sequentialtherapy with the standard triple therapy in Helicobacter pylori eradication. ...Side effect rates were also similar between the two groups. CONCLUSIONS: Ornidazole-based sequential therapy did not sh …
The aim of this study is to compare the ornidazole-based sequentialtherapy with the standard triple therapy in Helicobacter pylori er …
Ornidazole versus clindamycin: comparative evaluation in the treatment of 140 serious anaerobic infections.
Giamarellou H, Volanaki M, Avlami A, Tsatsiadis K, Petrochilos E, Daikos GK. Giamarellou H, et al. Chemotherapy. 1982;28(6):502-11. doi: 10.1159/000238140. Chemotherapy. 1982. PMID: 6761082 Clinical Trial.
A randomised prospective clinico-laboratory evaluation of the efficacy of ornidazole versus clindamycin in anaerobic infections was performed in 140 patients; 67 were given ornidazole and 73 received clindamycin. ...Between the two groups no statistically significan …
A randomised prospective clinico-laboratory evaluation of the efficacy of ornidazole versus clindamycin in anaerobic infections was p …
68 results