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Succinate receptor mediates intestinal inflammation and fibrosis.

Macias-Ceja DC, Ortiz-Masiá D, Salvador P, Gisbert-Ferrándiz L, Hernández C, Hausmann M, Rogler G, Esplugues JV, Hinojosa J, Alós R, Navarro F, Cosin-Roger J, Calatayud S, Barrachina MD. Macias-Ceja DC, et al. Mucosal Immunol. 2019 Jan;12(1):178-187. doi: 10.1038/s41385-018-0087-3. Epub 2018 Oct 2. Mucosal Immunol. 2019. PMID: 30279517

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Macrophages as an Emerging Source of Wnt Ligands: Relevance in Mucosal Integrity.

Cosin-Roger J, Ortiz-Masià MD, Barrachina MD. Cosin-Roger J, et al. Front Immunol. 2019 Sep 24;10:2297. doi: 10.3389/fimmu.2019.02297. eCollection 2019. Front Immunol. 2019. PMID: 31608072 Free PMC article. Review.

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Autophagy Stimulation as a Potential Strategy Against Intestinal Fibrosis.

Cosin-Roger J, Canet F, Macias-Ceja DC, Gisbert-Ferrándiz L, Ortiz-Masiá D, Esplugues JV, Alós R, Navarro F, Barrachina MD, Calatayud S. Cosin-Roger J, et al. Cells. 2019 Sep 13;8(9):1078. doi: 10.3390/cells8091078. Cells. 2019. PMID: 31540207 Free PMC article.

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Stimulation of autophagy prevents intestinal mucosal inflammation and ameliorates murine colitis.

Macias-Ceja DC, Cosín-Roger J, Ortiz-Masiá D, Salvador P, Hernández C, Esplugues JV, Calatayud S, Barrachina MD. Macias-Ceja DC, et al. Br J Pharmacol. 2017 Aug;174(15):2501-2511. doi: 10.1111/bph.13860. Epub 2017 Jun 21. Br J Pharmacol. 2017. PMID: 28500644 Free PMC article.

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CD16+ Macrophages Mediate Fibrosis in Inflammatory Bowel Disease.

Salvador P, Macías-Ceja DC, Gisbert-Ferrándiz L, Hernández C, Bernardo D, Alós R, Navarro-Vicente F, Esplugues JV, Ortiz-Masiá D, Barrachina MD, Calatayud S. Salvador P, et al. J Crohns Colitis. 2018 Apr 27;12(5):589-599. doi: 10.1093/ecco-jcc/jjx185. J Crohns Colitis. 2018. PMID: 29304229

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The activation of Wnt signaling by a STAT6-dependent macrophage phenotype promotes mucosal repair in murine IBD.

Cosín-Roger J, Ortiz-Masiá D, Calatayud S, Hernández C, Esplugues JV, Barrachina MD. Cosín-Roger J, et al. Mucosal Immunol. 2016 Jul;9(4):986-98. doi: 10.1038/mi.2015.123. Epub 2015 Nov 25. Mucosal Immunol. 2016. PMID: 26601901

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WNT2b Activates Epithelial-mesenchymal Transition Through FZD4: Relevance in Penetrating Crohn´s Disease.

Ortiz-Masià D, Salvador P, Macias-Ceja DC, Gisbert-Ferrándiz L, Esplugues JV, Manyé J, Alós R, Navarro-Vicente F, Mamie C, Scharl M, Cosin-Roger J, Calatayud S, Barrachina MD. Ortiz-Masià D, et al. J Crohns Colitis. 2020 Feb 10;14(2):230-239. doi: 10.1093/ecco-jcc/jjz134. J Crohns Colitis. 2020. PMID: 31359032

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Indomethacin Disrupts Autophagic Flux by Inducing Lysosomal Dysfunction in Gastric Cancer Cells and Increases Their Sensitivity to Cytotoxic Drugs.

Vallecillo-Hernández J, Barrachina MD, Ortiz-Masiá D, Coll S, Esplugues JV, Calatayud S, Hernández C. Vallecillo-Hernández J, et al. Sci Rep. 2018 Feb 26;8(1):3593. doi: 10.1038/s41598-018-21455-1. Sci Rep. 2018. PMID: 29483523 Free PMC article.

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A Single Nucleotide Polymorphism in the Vitamin D Receptor Gene Is Associated With Decreased Levels of the Protein and a Penetrating Pattern in Crohn's Disease.

Gisbert-Ferrándiz L, Salvador P, Ortiz-Masiá D, Macías-Ceja DC, Orden S, Esplugues JV, Calatayud S, Hinojosa J, Barrachina MD, Hernández C. Gisbert-Ferrándiz L, et al. Inflamm Bowel Dis. 2018 Jun 8;24(7):1462-1470. doi: 10.1093/ibd/izy094. Inflamm Bowel Dis. 2018. PMID: 29788141

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M1 Macrophages Activate Notch Signalling in Epithelial Cells: Relevance in Crohn's Disease.

Ortiz-Masiá D, Cosín-Roger J, Calatayud S, Hernández C, Alós R, Hinojosa J, Esplugues JV, Barrachina MD. Ortiz-Masiá D, et al. J Crohns Colitis. 2016 May;10(5):582-92. doi: 10.1093/ecco-jcc/jjw009. Epub 2016 Jan 22. J Crohns Colitis. 2016. PMID: 26802079 Free PMC article.

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