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Succinate receptor mediates intestinal inflammation and fibrosis.

Macias-Ceja DC, Ortiz-Masiá D, Salvador P, Gisbert-Ferrándiz L, Hernández C, Hausmann M, Rogler G, Esplugues JV, Hinojosa J, Alós R, Navarro F, Cosin-Roger J, Calatayud S, Barrachina MD. Macias-Ceja DC, et al. Mucosal Immunol. 2019 Jan;12(1):178-187. doi: 10.1038/s41385-018-0087-3. Epub 2018 Oct 2. Mucosal Immunol. 2019. PMID: 30279517

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Metabolite Sensing GPCRs: Promising Therapeutic Targets for Cancer Treatment?

Cosín-Roger J, Ortiz-Masia D, Barrachina MD, Calatayud S. Cosín-Roger J, et al. Cells. 2020 Oct 23;9(11):2345. doi: 10.3390/cells9112345. Cells. 2020. PMID: 33113952 Free PMC article. Review.

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Autophagy Stimulation as a Potential Strategy Against Intestinal Fibrosis.

Cosin-Roger J, Canet F, Macias-Ceja DC, Gisbert-Ferrándiz L, Ortiz-Masiá D, Esplugues JV, Alós R, Navarro F, Barrachina MD, Calatayud S. Cosin-Roger J, et al. Cells. 2019 Sep 13;8(9):1078. doi: 10.3390/cells8091078. Cells. 2019. PMID: 31540207 Free PMC article.

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Macrophages as an Emerging Source of Wnt Ligands: Relevance in Mucosal Integrity.

Cosin-Roger J, Ortiz-Masià MD, Barrachina MD. Cosin-Roger J, et al. Front Immunol. 2019 Sep 24;10:2297. doi: 10.3389/fimmu.2019.02297. eCollection 2019. Front Immunol. 2019. PMID: 31608072 Free PMC article. Review.

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CD16+ Macrophages Mediate Fibrosis in Inflammatory Bowel Disease.

Salvador P, Macías-Ceja DC, Gisbert-Ferrándiz L, Hernández C, Bernardo D, Alós R, Navarro-Vicente F, Esplugues JV, Ortiz-Masiá D, Barrachina MD, Calatayud S. Salvador P, et al. J Crohns Colitis. 2018 Apr 27;12(5):589-599. doi: 10.1093/ecco-jcc/jjx185. J Crohns Colitis. 2018. PMID: 29304229

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WNT2b Activates Epithelial-mesenchymal Transition Through FZD4: Relevance in Penetrating Crohn´s Disease.

Ortiz-Masià D, Salvador P, Macias-Ceja DC, Gisbert-Ferrándiz L, Esplugues JV, Manyé J, Alós R, Navarro-Vicente F, Mamie C, Scharl M, Cosin-Roger J, Calatayud S, Barrachina MD. Ortiz-Masià D, et al. J Crohns Colitis. 2020 Feb 10;14(2):230-239. doi: 10.1093/ecco-jcc/jjz134. J Crohns Colitis. 2020. PMID: 31359032

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Succinate Activates EMT in Intestinal Epithelial Cells through SUCNR1: A Novel Protagonist in Fistula Development.

Ortiz-Masiá D, Gisbert-Ferrándiz L, Bauset C, Coll S, Mamie C, Scharl M, Esplugues JV, Alós R, Navarro F, Cosín-Roger J, Barrachina MD, Calatayud S. Ortiz-Masiá D, et al. Cells. 2020 Apr 29;9(5):1104. doi: 10.3390/cells9051104. Cells. 2020. PMID: 32365557 Free PMC article.

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Diminished Vitamin D Receptor Protein Levels in Crohn's Disease Fibroblasts: Effects of Vitamin D.

Gisbert-Ferrándiz L, Cosín-Roger J, Hernández C, Macias-Ceja DC, Ortiz-Masiá D, Salvador P, Esplugues JV, Hinojosa J, Navarro F, Calatayud S, Barrachina MD. Gisbert-Ferrándiz L, et al. Nutrients. 2020 Apr 1;12(4):973. doi: 10.3390/nu12040973. Nutrients. 2020. PMID: 32244667 Free PMC article.

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The vitamin D receptor Taq I polymorphism is associated with reduced VDR and increased PDIA3 protein levels in human intestinal fibroblasts.

Gisbert-Ferrándiz L, Cosin-Roger J, Hernández C, Macias-Ceja DC, Ortiz-Masiá D, Salvador P, Wildenberg ME, Esplugues JV, Alós R, Navarro F, Calatayud S, Barrachina MD. Gisbert-Ferrándiz L, et al. J Steroid Biochem Mol Biol. 2020 Sep;202:105720. doi: 10.1016/j.jsbmb.2020.105720. Epub 2020 Jun 18. J Steroid Biochem Mol Biol. 2020. PMID: 32565249

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Stimulation of autophagy prevents intestinal mucosal inflammation and ameliorates murine colitis.

Macias-Ceja DC, Cosín-Roger J, Ortiz-Masiá D, Salvador P, Hernández C, Esplugues JV, Calatayud S, Barrachina MD. Macias-Ceja DC, et al. Br J Pharmacol. 2017 Aug;174(15):2501-2511. doi: 10.1111/bph.13860. Epub 2017 Jun 21. Br J Pharmacol. 2017. PMID: 28500644 Free PMC article.

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