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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 1
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2001 1
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2006 2
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2010 7
2011 6
2012 10
2013 12
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343 results

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Page 1
GLP-1-Based Therapies in Pain Medicine: A Narrative Review and Expert Opinion on Obesity-Related Low Back and Knee Pain.
Hasoon J, Nguyen A, Viswanath O, Urits I, Robinson CL. Hasoon J, et al. Curr Pain Headache Rep. 2026 Aug 10;30(1):105. doi: 10.1007/s11916-026-01546-9. Curr Pain Headache Rep. 2026. PMID: 42572056 Review.
Obesity is associated with low back pain and knee osteoarthritis, and weight reduction has been shown to improve pain and function in these conditions. GLP-1-based therapies can produce clinically meaningful weight loss in patients with o …
Obesity is associated with low back pain and knee osteoarthritis, and weight reduction has been shown to improve pai …
The central role of IL-6 in the differential effects of GLP-1 receptor agonists and metformin across multiple health conditions.
Elkoshi Z. Elkoshi Z. Front Immunol. 2026 Jul 21;17:1864104. doi: 10.3389/fimmu.2026.1864104. eCollection 2026. Front Immunol. 2026. PMID: 42553087 Free PMC article. Review.
Superior weight loss, which is IL-6 independent, further enhances the efficacy of GLP-1 RAs in improving metabolic dysfunction-associated steatohepatitis (MASH), PCOS, and survival in cancer patients. ...Metformin also reduces osteoarthritis-related joint …
Superior weight loss, which is IL-6 independent, further enhances the efficacy of GLP-1 RAs in improving metabolic dysfunction …
Vitamin D and Curcumin Mitigate ACLT + MMx-Induced Knee Osteoarthritis by Improving Antioxidant-Related Nrf2/HO-1 Expression and Reducing Synovial Inflammation.
Mende LK, Kuthati Y, Wong CS. Mende LK, et al. Nutrients. 2026 Jul 13;18(14):2288. doi: 10.3390/nu18142288. Nutrients. 2026. PMID: 42514357 Free PMC article.
Background: Osteoarthritis (OA) is mainly driven by mechanical damage together with persistent oxidative stress and synovial inflammation, leading to progressive cartilage loss and functional impairment. ...Rats were assigned to Sham, OA-control (Control), vitamin D …
Background: Osteoarthritis (OA) is mainly driven by mechanical damage together with persistent oxidative stress and synovial inflamma …
Medical Treatments for Obesity: What Does the Future Have in Store?
Bassatne A, Rizo I. Bassatne A, et al. J Clin Endocrinol Metab. 2026 Jul 14:dgag274. doi: 10.1210/clinem/dgag274. Online ahead of print. J Clin Endocrinol Metab. 2026. PMID: 42444567
Phase 2 and 3 clinical trials evaluating emerging obesity pharmacotherapies in adults and reporting outcomes, including weight loss and obesity-related complications, were included. EVIDENCE SYNTHESIS: Entero-pancreatic hormone-based therapies targeting GLP-1 …
Phase 2 and 3 clinical trials evaluating emerging obesity pharmacotherapies in adults and reporting outcomes, including weight …
Surgery for early structural osteoarthritis of the hip and knee: the SCORE evidence synthesis and economic evaluation.
Price A, Searle E, Westby M, Fabiano G, Royle P, Colquitt J, Loveman E, Barker K, Glyn-Jones S, Palmer A, Mistry H, Smith T, Metcalfe A, Villanueva RP, Hopewell S. Price A, et al. Health Technol Assess. 2026 Jul;30(56):1-150. doi: 10.3310/TNFD7352. Health Technol Assess. 2026. PMID: 42439308 Free PMC article.
They were compared with non-surgical treatment following National Institute for Health and Care Excellence guidance. We used outcome measures that satisfied the Outcome Measures in Rheumatoid Arthritis Clinical Trials and Osteoarthritis Research Society Inter …
They were compared with non-surgical treatment following National Institute for Health and Care Excellence guidance. We used outcome …
Intensive diet or knee arthroplasty for severe knee osteoarthritis: The inka randomised trial.
Henriksen M, Christensen R, Poulsen AS, Bunyoz KI, Aljuboori SM, Nielsen CT, Haugegaard T, Gudbergsen H, Gromov K, Døssing A, Leeds A, Overgaard S, Troelsen A, Bliddal H. Henriksen M, et al. Osteoarthritis Cartilage. 2026 Jul 10:S1063-4584(26)00977-5. doi: 10.1016/j.joca.2026.07.004. Online ahead of print. Osteoarthritis Cartilage. 2026. PMID: 42431586 Free article.
OBJECTIVE: To test whether an intensive dietary weight loss program (IN) yields non-inferior symptom improvement vs. knee arthroplasty (KA) in people with knee osteoarthritis eligible for knee arthroplasty. ...CONCLUSION: Among people with obesity and severe …
OBJECTIVE: To test whether an intensive dietary weight loss program (IN) yields non-inferior symptom improvement vs. knee arth …
Percutaneous compression screw fixation for hinge fractures in distal femoral osteotomy does not compromise radiographic or clinical outcomes: A retrospective case-control study.
Relot V, Siret E, Liguori T, Patel R, Piercecchi A, Ollivier M. Relot V, et al. J Exp Orthop. 2026 Jun 30;13(3):e70830. doi: 10.1002/jeo2.70830. eCollection 2026 Jul. J Exp Orthop. 2026. PMID: 42382086 Free PMC article.
Radiographic parameters-including coronal correction (deltaHKA: change in hip-knee-ankle angle), alignment maintenance and radiographic union-and patient-reported outcome measures (Knee Injury and Osteoarthritis Outcome Score, Lysholm score, Simple Knee Value …
Radiographic parameters-including coronal correction (deltaHKA: change in hip-knee-ankle angle), alignment maintenance and radiographic unio …
GLP-1 receptor agonists and weight-loss strategies for individuals with obesity and hip or knee osteoarthritis: a scoping review.
McCann CJ, Clement ND, Murray A, Kearney R, Madigan S, Gee CW, Walmsley P, Morrison S, Chopra S, Hall AJ. McCann CJ, et al. Br J Sports Med. 2026 Jul 23:bjsports-2025-111225. doi: 10.1136/bjsports-2025-111225. Online ahead of print. Br J Sports Med. 2026. PMID: 42321007
OBJECTIVE: To map current strategies for weight loss in hip and knee osteoarthritis (OA), with emphasis on the emerging role of glucagon-like peptide-1 receptor agonists (GLP-1-RAs) as tools in achieving weight loss and impacting symptoms, disea …
OBJECTIVE: To map current strategies for weight loss in hip and knee osteoarthritis (OA), with emphasis on the emerging …
Dual amylin and calcitonin receptor agonists as multifaceted disease-modifying osteoarthritis drugs.
Mohamed KE, Larsen AT, Thudium CS, Bezerra A, Karsdal MA, Bay-Jensen AC, Henriksen K. Mohamed KE, et al. Int J Obes (Lond). 2026 Jul;50(7):1415-1425. doi: 10.1038/s41366-026-02124-0. Epub 2026 Jun 9. Int J Obes (Lond). 2026. PMID: 42265185 Review.
Weight loss is a cornerstone of OA management, improving patients' quality of life and disease outcomes. ...DACRAs induce weight loss by activating the amylin receptor, thereby improving patients' quality of life and reducing OA pain inte …
Weight loss is a cornerstone of OA management, improving patients' quality of life and disease outcomes. ...DACRAs indu …
A mobile intervention to reduce pain and improve health-III: protocol for a remotely delivered randomized controlled trial of physical activity for pain management in older adults with obesity and knee or hip osteoarthritis.
Fanning J, Dobson DO, Ford SA, Bennett M, Leng I, Martin AC, Merritt J, Keefe FJ, Rejeski WJ, Brooks AK. Fanning J, et al. Front Digit Health. 2026 May 21;8:1739501. doi: 10.3389/fdgth.2026.1739501. eCollection 2026. Front Digit Health. 2026. PMID: 42255285 Free PMC article.
Outcomes of interest include daily steps (primary outcome) and pain interference, body weight, and physical function (secondary outcomes). ...Low-active older adults (N = 200) with chronic osteoarthritic hip and/or knee pain and obesity w …
Outcomes of interest include daily steps (primary outcome) and pain interference, body weight, and physical func …
343 results