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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1915 1
1924 1
1928 1
1932 1
1933 1
1937 1
1948 3
1950 1
1952 1
1953 1
1954 1
1955 1
1956 2
1957 3
1958 1
1959 4
1962 3
1963 2
1964 8
1965 5
1966 9
1967 5
1968 10
1969 12
1970 18
1971 33
1972 30
1973 24
1974 27
1975 249
1976 224
1977 254
1978 233
1979 257
1980 274
1981 277
1982 283
1983 320
1984 339
1985 385
1986 352
1987 343
1988 382
1989 444
1990 466
1991 477
1992 517
1993 563
1994 560
1995 520
1996 575
1997 675
1998 682
1999 710
2000 772
2001 829
2002 913
2003 994
2004 994
2005 1307
2006 1424
2007 1423
2008 1545
2009 1771
2010 1791
2011 2028
2012 2148
2013 2345
2014 2595
2015 2638
2016 2858
2017 2980
2018 3068
2019 2982
2020 3261
2021 3268
2022 2984
2023 2989
2024 3135
2025 3648
2026 2263

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61,795 results

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Page 1
Interactions between the gut microbiota and immune cell dynamics: novel insights into the gut-bone axis.
You Y, Xiang T, Yang C, Xiao S, Tang Y, Luo G, Ling Z, Luo F, Chen Y. You Y, et al. Gut Microbes. 2025 Dec;17(1):2545417. doi: 10.1080/19490976.2025.2545417. Epub 2025 Aug 28. Gut Microbes. 2025. PMID: 40873417 Free PMC article. Review.
Over the past few decades, accumulating evidence has demonstrated that gut microbiota engages in a sustained dialog with the immune system, leading to microbiota-driven immune responses that mediate the regulation of bone-related diseases. ...The review that …
Over the past few decades, accumulating evidence has demonstrated that gut microbiota engages in a sustained dialog with the immune s …
Molecular mechanisms and therapeutic implications of the sympathetic nervous system in bone-related disorders: a brain-bone axis perspective.
Liu M, Liu Y, Yu J, Gong J, Zhao C, Liu Z. Liu M, et al. Bone Res. 2025 Dec 2;13(1):98. doi: 10.1038/s41413-025-00494-1. Bone Res. 2025. PMID: 41326350 Free PMC article. Review.
The global aging crisis has increased the prevalence of skeletal disorders, necessitating innovative therapeutic strategies. This review employs the brain-bone axis (BBA) framework to examine the role of the sympathetic nervous system (SNS) in bone metabolism. ...By …
The global aging crisis has increased the prevalence of skeletal disorders, necessitating innovative therapeutic strategies. This review emp …
KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD).
Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Work Group. Kidney Disease: Improving Global Outcomes (KDIGO) CKD-MBD Work Group. Kidney Int Suppl. 2009 Aug;(113):S1-130. doi: 10.1038/ki.2009.188. Kidney Int Suppl. 2009. PMID: 19644521 Free article.
Tests considered are those that relate to the detection and monitoring of laboratory, bone, and cardiovascular abnormalities. Treatments considered are interventions to treat hyperphosphatemia, hyperparathyroidism, and bone disease in patients with CKD stages 3-5D a …
Tests considered are those that relate to the detection and monitoring of laboratory, bone, and cardiovascular abnormalities. Treatme …
History of syphilis.
Rothschild BM. Rothschild BM. Clin Infect Dis. 2005 May 15;40(10):1454-63. doi: 10.1086/429626. Epub 2005 Apr 1. Clin Infect Dis. 2005. PMID: 15844068 Review.
Evidence-based research now allows clear separation of syphilis from other diseases in its class of treponematoses. Examination of skeletons from populations with clinically diagnosed bejel and yaws revealed bone alterations distinctive to those diseases …
Evidence-based research now allows clear separation of syphilis from other diseases in its class of treponematoses. Examinatio …
Thalassemic osteoarthropathy.
Gratwick GM, Bullough PG, Bohne WH, Markenson AL, Peterson CM. Gratwick GM, et al. Ann Intern Med. 1978 Apr;88(4):494-501. doi: 10.7326/0003-4819-88-4-494. Ann Intern Med. 1978. PMID: 637429
Twenty-five of 50 patients between the ages of 5 and 33 years had evidence of periarticular disease that consisted of dull-aching ankle pain exacerbated by weight bearing and relieved by rest. Involvement was symmetrical with mild swelling and pain on bone compressi …
Twenty-five of 50 patients between the ages of 5 and 33 years had evidence of periarticular disease that consisted of dull-aching ank …
Vertebral fracture epidemiology.
Wasnich RD. Wasnich RD. Bone. 1996 Mar;18(3 Suppl):179S-183S. doi: 10.1016/8756-3282(95)00499-8. Bone. 1996. PMID: 8777085 Review.
Risk factors fall into five major categories: (1) age, or age-related, (2) genetic, (3) environmental, (40 endogenous hormones or chronic diseases, and (5) physical characteristics of bone. Bone density is the most clinically useful risk factor, particularly …
Risk factors fall into five major categories: (1) age, or age-related, (2) genetic, (3) environmental, (40 endogenous hormones or chronic …
[Methotrexate osteopathy-a critical review].
Braun J, Buehring B. Braun J, et al. Z Rheumatol. 2026 Apr;85(3):240-246. doi: 10.1007/s00393-025-01755-4. Epub 2025 Dec 1. Z Rheumatol. 2026. PMID: 41324647 Review. German.
Since the early 1980s, MTX has become indispensable in the treatment of rheumatoid arthritis and is established worldwide as the standard of care for the treatment of many inflammatory rheumatic diseases. The mechanism of action of MTX is not completely understood; the ade …
Since the early 1980s, MTX has become indispensable in the treatment of rheumatoid arthritis and is established worldwide as the standard of …
Cancer-associated bone disease.
Rizzoli R, Body JJ, Brandi ML, Cannata-Andia J, Chappard D, El Maghraoui A, Glüer CC, Kendler D, Napoli N, Papaioannou A, Pierroz DD, Rahme M, Van Poznak CH, de Villiers TJ, El Hajj Fuleihan G; International Osteoporosis Foundation Committee of Scientific Advisors Working Group on Cancer-Induced Bone Disease. Rizzoli R, et al. Osteoporos Int. 2013 Dec;24(12):2929-53. doi: 10.1007/s00198-013-2530-3. Epub 2013 Oct 22. Osteoporos Int. 2013. PMID: 24146095 Free PMC article. Review.
Some evidence demonstrates the efficacy of various interventions including bone-modifying agents, such as bisphosphonates and denosumab, in preventing or delaying cancer-related bone disease. ...The goal of this paper is to put forth an IOF position paper add …
Some evidence demonstrates the efficacy of various interventions including bone-modifying agents, such as bisphosphonates and …
Osteoprotegerin in diabetic osteopathy.
Valentini A, Cianfarani MA, Federici M, Tarantino U, Bertoli A. Valentini A, et al. Nutr Metab Cardiovasc Dis. 2020 Jan 3;30(1):49-55. doi: 10.1016/j.numecd.2019.08.018. Epub 2019 Sep 9. Nutr Metab Cardiovasc Dis. 2020. PMID: 31757570
CONCLUSIONS: Diabetic patients have reduced circulating levels of OC and CTX, and elevated serum levels of OPG, suggesting a state of low bone turnover. Reduced bone turnover causes an increase of BMD and could lead to a poor bone quality. OPG and HbA1c were …
CONCLUSIONS: Diabetic patients have reduced circulating levels of OC and CTX, and elevated serum levels of OPG, suggesting a state of low …
61,795 results
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