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Year Number of Results
1987 1
1988 1
1989 1
1990 2
1991 1
1998 1
1999 4
2000 1
2003 3
2004 2
2005 7
2006 3
2007 2
2008 2
2009 1
2010 10
2011 12
2012 19
2013 15
2014 15
2015 18
2016 13
2017 19
2018 11
2019 12
2020 12
2021 36
2022 56
2023 64

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Page 1
Clonal hematopoiesis of indeterminate potential in Persons living with HIV.
Knudsen AD, Eskelund CW, Benfield T, Zhao Y, Gelpi M, Køber L, Trøseid M, Kofoed KF, Ostrowski SR, Reilly C, Borges ÁH, Grønbæk K, Nielsen SD. Knudsen AD, et al. AIDS. 2023 Nov 16. doi: 10.1097/QAD.0000000000003788. Online ahead of print. AIDS. 2023. PMID: 37976039
Genetic prediction of 33 blood group phenotypes using an existing genotype dataset.
Moslemi C, Saekmose SG, Larsen R, Bay JT, Brodersen T, Didriksen M, Hjalgrim H, Banasik K, Nielsen KR, Bruun MT, Dowsett J, Dinh KM, Mikkelsen S, Mikkelsen C, Hansen TF, Ullum H, Erikstrup C, Brunak S, Krogfelt KA, Storry JR, Ostrowski SR, Olsson ML, Pedersen OB. Moslemi C, et al. Transfusion. 2023 Nov 3. doi: 10.1111/trf.17575. Online ahead of print. Transfusion. 2023. PMID: 37921035
An atlas of genetic determinants of forearm fracture.
Nethander M, Movérare-Skrtic S, Kämpe A, Coward E, Reimann E, Grahnemo L, Borbély É, Helyes Z, Funck-Brentano T, Cohen-Solal M, Tuukkanen J, Koskela A, Wu J, Li L, Lu T, Gabrielsen ME; Estonian Biobank Research Team; Mägi R, Hoff M, Lerner UH, Henning P, Ullum H, Erikstrup C, Brunak S; DBDS Genomic Consortium; Langhammer A, Tuomi T, Oddsson A, Stefansson K, Pettersson-Kymmer U, Ostrowski SR, Pedersen OBV, Styrkarsdottir U, Mäkitie O, Hveem K, Richards JB, Ohlsson C. Nethander M, et al. Nat Genet. 2023 Nov;55(11):1820-1830. doi: 10.1038/s41588-023-01527-3. Epub 2023 Nov 2. Nat Genet. 2023. PMID: 37919453 Free PMC article.
Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura.
Bjornsdottir G, Chalmer MA, Stefansdottir L, Skuladottir AT, Einarsson G, Andresdottir M, Beyter D, Ferkingstad E, Gretarsdottir S, Halldorsson BV, Halldorsson GH, Helgadottir A, Helgason H, Hjorleifsson Eldjarn G, Jonasdottir A, Jonasdottir A, Jonsdottir I, Knowlton KU, Nadauld LD, Lund SH, Magnusson OT, Melsted P, Moore KHS, Oddsson A, Olason PI, Sigurdsson A, Stefansson OA, Saemundsdottir J, Sveinbjornsson G, Tragante V, Unnsteinsdottir U, Walters GB, Zink F, Rødevand L, Andreassen OA, Igland J, Lie RT, Haavik J, Banasik K, Brunak S, Didriksen M, T Bruun M, Erikstrup C, Kogelman LJA, Nielsen KR, Sørensen E, Pedersen OB, Ullum H; DBDS Genetic Consortium; Masson G, Thorsteinsdottir U, Olesen J, Ludvigsson P, Thorarensen O, Bjornsdottir A, Sigurdardottir GR, Sveinsson OA, Ostrowski SR, Holm H, Gudbjartsson DF, Thorleifsson G, Sulem P, Stefansson H, Thorgeirsson TE, Hansen TF, Stefansson K. Bjornsdottir G, et al. Nat Genet. 2023 Nov;55(11):1843-1853. doi: 10.1038/s41588-023-01538-0. Epub 2023 Oct 26. Nat Genet. 2023. PMID: 37884687 Free PMC article.
Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target.
Roychowdhury T, Klarin D, Levin MG, Spin JM, Rhee YH, Deng A, Headley CA, Tsao NL, Gellatly C, Zuber V, Shen F, Hornsby WE, Laursen IH, Verma SS, Locke AE, Einarsson G, Thorleifsson G, Graham SE, Dikilitas O, Pattee JW, Judy RL, Pauls-Verges F, Nielsen JB, Wolford BN, Brumpton BM, Dilmé J, Peypoch O, Juscafresa LC, Edwards TL, Li D, Banasik K, Brunak S, Jacobsen RL, Garcia-Barrio MT, Zhang J, Rasmussen LM, Lee R, Handa A, Wanhainen A, Mani K, Lindholt JS, Obel LM, Strauss E, Oszkinis G, Nelson CP, Saxby KL, van Herwaarden JA, van der Laan SW, van Setten J, Camacho M, Davis FM, Wasikowski R, Tsoi LC, Gudjonsson JE, Eliason JL, Coleman DM, Henke PK, Ganesh SK, Chen YE, Guan W, Pankow JS, Pankratz N, Pedersen OB, Erikstrup C, Tang W, Hveem K, Gudbjartsson D, Gretarsdottir S, Thorsteinsdottir U, Holm H, Stefansson K, Ferreira MA, Baras A, Kullo IJ, Ritchie MD, Christensen AH, Iversen KK, Eldrup N, Sillesen H, Ostrowski SR, Bundgaard H, Ullum H, Burgess S, Gill D, Gallagher K, Sabater-Lleal M; DiscovEHR; Regeneron Genetics Center; UK Aneurysm Growth Study; DBDS Genomic Consortium; VA Million Veteran Program; Surakka I, Jones GT, Bown MJ, Tsao PS, Willer CJ, Damrauer SM. Roychowdhury T, et al. Nat Genet. 2023 Nov;55(11):1831-1842. doi: 10.1038/s41588-023-01510-y. Epub 2023 Oct 16. Nat Genet. 2023. PMID: 37845353 Free PMC article.
Genome-wide association study of placental weight identifies distinct and shared genetic influences between placental and fetal growth.
Beaumont RN, Flatley C, Vaudel M, Wu X, Chen J, Moen GH, Skotte L, Helgeland Ø, Solé-Navais P, Banasik K, Albiñana C, Ronkainen J, Fadista J, Stinson SE, Trajanoska K, Wang CA, Westergaard D, Srinivasan S, Sánchez-Soriano C, Bilbao JR, Allard C, Groleau M, Kuulasmaa T, Leirer DJ, White F, Jacques PÉ, Cheng H, Hao K, Andreassen OA, Åsvold BO, Atalay M, Bhatta L, Bouchard L, Brumpton BM, Brunak S, Bybjerg-Grauholm J, Ebbing C, Elliott P, Engelbrechtsen L, Erikstrup C, Estarlich M, Franks S, Gaillard R, Geller F, Grove J, Hougaard DM, Kajantie E, Morgen CS, Nohr EA, Nyegaard M, Palmer CNA, Pedersen OB; Early Growth Genetics (EGG) Consortium; Rivadeneira F, Sebert S, Shields BM, Stoltenberg C, Surakka I, Thørner LW, Ullum H, Vaarasmaki M, Vilhjalmsson BJ, Willer CJ, Lakka TA, Gybel-Brask D, Bustamante M, Hansen T, Pearson ER, Reynolds RM, Ostrowski SR, Pennell CE, Jaddoe VWV, Felix JF, Hattersley AT, Melbye M, Lawlor DA, Hveem K, Werge T, Nielsen HS, Magnus P, Evans DM, Jacobsson B, Järvelin MR, Zhang G, Hivert MF, Johansson S, Freathy RM, Feenstra B, Njølstad PR. Beaumont RN, et al. Nat Genet. 2023 Nov;55(11):1807-1819. doi: 10.1038/s41588-023-01520-w. Epub 2023 Oct 5. Nat Genet. 2023. PMID: 37798380 Free PMC article.
Humoral immune response to COVID-19 vaccine in patients with myasthenia gravis.
Holm-Yildiz S, Dysgaard T, Krag T, Pedersen BS, Hamm SR, Pérez-Alós L, Hansen CB, Pries-Heje MM, Heftdal LD, Hasselbalch RB, Fogh K, Madsen JR, Frikke-Schmidt R, Hilsted LM, Sørensen E, Ostrowski SR, Bundgaard H, Garred P, Iversen K, Nielsen SD, Vissing J. Holm-Yildiz S, et al. J Neuroimmunol. 2023 Nov 15;384:578215. doi: 10.1016/j.jneuroim.2023.578215. Epub 2023 Sep 28. J Neuroimmunol. 2023. PMID: 37797472 Free article.
Complex effects of sequence variants on lipid levels and coronary artery disease.
Snaebjarnarson AS, Helgadottir A, Arnadottir GA, Ivarsdottir EV, Thorleifsson G, Ferkingstad E, Einarsson G, Sveinbjornsson G, Thorgeirsson TE, Ulfarsson MO, Halldorsson BV, Olafsson I, Erikstrup C, Pedersen OB, Nyegaard M, Bruun MT, Ullum H, Brunak S, Iversen KK, Christensen AH, Olesen MS, Ghouse J, Banasik K; DBDS Genomic Consortium; Knowlton KU, Arnar DO, Thorgeirsson G, Nadauld L, Ostrowski SR, Bundgaard H, Holm H, Sulem P, Stefansson K, Gudbjartsson DF. Snaebjarnarson AS, et al. Cell. 2023 Sep 14;186(19):4085-4099.e15. doi: 10.1016/j.cell.2023.08.012. Cell. 2023. PMID: 37714134
Previous immunity shapes immune responses to SARS-CoV-2 booster vaccination and Omicron breakthrough infection risk.
Pérez-Alós L, Hansen CB, Almagro Armenteros JJ, Madsen JR, Heftdal LD, Hasselbalch RB, Pries-Heje MM, Bayarri-Olmos R, Jarlhelt I, Hamm SR, Møller DL, Sørensen E, Ostrowski SR, Frikke-Schmidt R, Hilsted LM, Bundgaard H, Nielsen SD, Iversen KK, Garred P. Pérez-Alós L, et al. Nat Commun. 2023 Sep 12;14(1):5624. doi: 10.1038/s41467-023-41342-2. Nat Commun. 2023. PMID: 37699890 Free PMC article.
SARS-CoV-2 vaccine-induced antibodies protect against Omicron breakthrough infection.
Baerends EAM, Hvidt AK, Reekie J, Søgaard OS, Stærke NB, Raben D, Nielsen H, Petersen KT, Juhl MR, Johansen IS, Lindvig SO, Madsen LW, Wiese L, Knudsen LS, Iversen MB, Benfield T, Iversen KK, Andersen SD, Juhl AK, Dietz LL, Andreasen SR, Fischer TK, Erikstrup C, Valentiner-Branth P, Lundgren J, Østergaard L, Tolstrup M; ENFORCE Study Group. Baerends EAM, et al. iScience. 2023 Aug 14;26(9):107621. doi: 10.1016/j.isci.2023.107621. eCollection 2023 Sep 15. iScience. 2023. PMID: 37682631 Free PMC article.
Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage.
Westergaard D, Steinthorsdottir V, Stefansdottir L, Rohde PD, Wu X, Geller F, Tyrmi J, Havulinna AS, Navais PS, Flatley C, Ostrowski SR, Pedersen OB, Erikstrup C, Sørensen E, Mikkelsen C, Brun MT, Jensen BA, Brodersen T, Ullum H; FinnGen; Danish Blood Donor Study Genomic Consortium; Estonian Biobank Research Team; Nordic Collaboration for Womens and Reproductive Health; Magnus P, Andreassen OA, Njolstad PR, Kolte AM, Krebs L, Nyegaard M, Hansen TF, Fenstra B, Daly M, Lindgren CM, Thorleifsson G, Stefansson OA, Sveinbjornsson G, Gudbjartsson DF, Thorsteinsdottir U, Banasik K, Jacobsson B, Laisk T, Laivuori H, Stefansson K, Brunak S, Nielsen HS. Westergaard D, et al. medRxiv. 2023 Aug 15:2023.08.10.23293932. doi: 10.1101/2023.08.10.23293932. Preprint. medRxiv. 2023. PMID: 37645979 Free PMC article.
Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events.
Helgason H, Eiriksdottir T, Ulfarsson MO, Choudhary A, Lund SH, Ivarsdottir EV, Hjorleifsson Eldjarn G, Einarsson G, Ferkingstad E, Moore KHS, Honarpour N, Liu T, Wang H, Hucko T, Sabatine MS, Morrow DA, Giugliano RP, Ostrowski SR, Pedersen OB, Bundgaard H, Erikstrup C, Arnar DO, Thorgeirsson G, Masson G, Magnusson OT, Saemundsdottir J, Gretarsdottir S, Steinthorsdottir V, Thorleifsson G, Helgadottir A, Sulem P, Thorsteinsdottir U, Holm H, Gudbjartsson D, Stefansson K. Helgason H, et al. JAMA. 2023 Aug 22;330(8):725-735. doi: 10.1001/jama.2023.13258. JAMA. 2023. PMID: 37606673 Clinical Trial.
Understanding the genetic complexity of puberty timing across the allele frequency spectrum.
Kentistou KA, Kaisinger LR, Stankovic S, Vaudel M, de Oliveira EM, Messina A, Walters RG, Liu X, Busch AS, Helgason H, Thompson DJ, Santon F, Petricek KM, Zouaghi Y, Huang-Doran I, Gudbjartsson DF, Bratland E, Lin K, Gardner EJ, Zhao Y, Jia R, Terao C, Riggan M, Bolla MK, Yazdanpanah M, Yazdanpanah N, Bradfield JP, Broer L, Campbell A, Chasman DI, Cousminer DL, Franceschini N, Franke LH, Girotto G, He C, Järvelin MR, Joshi PK, Kamatani Y, Karlsson R, Luan J, Lunetta KL, Mägi R, Mangino M, Medland SE, Meisinger C, Noordam R, Nutile T, Concas MP, Polašek O, Porcu E, Ring SM, Sala C, Smith AV, Tanaka T, van der Most PJ, Vitart V, Wang CA, Willemsen G, Zygmunt M, Ahearn TU, Andrulis IL, Anton-Culver H, Antoniou AC, Auer PL, Barnes CL, Beckmann MW, Berrington A, Bogdanova NV, Bojesen SE, Brenner H, Buring JE, Canzian F, Chang-Claude J, Couch FJ, Cox A, Crisponi L, Czene K, Daly MB, Demerath EW, Dennis J, Devilee P, Vivo I, Dörk T, Dunning AM, Dwek M, Eriksson JG, Fasching PA, Fernandez-Rhodes L, Ferreli L, Fletcher O, Gago-Dominguez M, García-Closas M, García-Sáenz JA, González-Neira A, Grallert H, Guénel P, Haiman CA, Hall P, Hamann U, Hakonarson H, Hart RJ, Hickey M, Hooning MJ, Hopp… See abstract for full author list ➔ Kentistou KA, et al. medRxiv. 2023 Jun 20:2023.06.14.23291322. doi: 10.1101/2023.06.14.23291322. Preprint. medRxiv. 2023. PMID: 37503126 Free PMC article.
Cluster Headache Genomewide Association Study and Meta-Analysis Identifies Eight Loci and Implicates Smoking as Causal Risk Factor.
Winsvold BS, Harder AVE, Ran C, Chalmer MA, Dalmasso MC, Ferkingstad E, Tripathi KP, Bacchelli E, Børte S, Fourier C, Petersen AS, Vijfhuizen LS, Magnusson SH, O'Connor E, Bjornsdottir G, Häppölä P, Wang YF, Callesen I, Kelderman T, Gallardo VJ, de Boer I, Olofsgård FJ, Heinze K, Lund N, Thomas LF, Hsu CL, Pirinen M, Hautakangas H, Ribasés M, Guerzoni S, Sivakumar P, Yip J, Heinze A, Küçükali F, Ostrowski SR, Pedersen OB, Kristoffersen ES, Martinsen AE, Artigas MS, Lagrata S, Cainazzo MM, Adebimpe J, Quinn O, Göbel C, Cirkel A, Volk AE, Heilmann-Heimbach S, Skogholt AH, Gabrielsen ME, Wilbrink LA, Danno D, Mehta D, Guðbjartsson DF; HUNT All-In Headache, The International Headache Genetics Consortium, DBDS Genomic Consortium; Rosendaal FR, Willems van Dijk K, Fronczek R, Wagner M, Scherer M, Göbel H, Sleegers K, Sveinsson OA, Pani L, Zoli M, Ramos-Quiroga JA, Dardiotis E, Steinberg A, Riedel-Heller S, Sjöstrand C, Thorgeirsson TE, Stefansson H, Southgate L, Trembath RC, Vandrovcova J, Noordam R, Paemeleire K, Stefansson K, Fann CS, Waldenlind E, Tronvik E, Jensen RH, Chen SP, Houlden H, Terwindt GM, Kubisch C, Maestrini E, Vikelis M, Pozo-Rosich P, Belin AC, Matharu M, van den Maag… See abstract for full author list ➔ Winsvold BS, et al. Ann Neurol. 2023 Oct;94(4):713-726. doi: 10.1002/ana.26743. Epub 2023 Aug 7. Ann Neurol. 2023. PMID: 37486023
The effect of ferritin-guided iron supplementation among Danish female first-time blood donors.
Drechsler LØ, Boldsen JK, Hindhede L, Aagaard B, Harritshøj LH, Mikkelsen C, Brodersen T, Brøns N, Schwinn M, Hjalgrim H, Rostgaard K, Topholm Bruun M, Ostrowski SR, Pedersen OB, Mikkelsen S, Erikstrup C. Drechsler LØ, et al. Transfusion. 2023 Sep;63(9):1710-1718. doi: 10.1111/trf.17484. Epub 2023 Jul 14. Transfusion. 2023. PMID: 37452554
Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality.
Oddsson A, Sulem P, Sveinbjornsson G, Arnadottir GA, Steinthorsdottir V, Halldorsson GH, Atlason BA, Oskarsson GR, Helgason H, Nielsen HS, Westergaard D, Karjalainen JM, Katrinardottir H, Fridriksdottir R, Jensson BO, Tragante V, Ferkingstad E, Jonsson H, Gudjonsson SA, Beyter D, Moore KHS, Thordardottir HB, Kristmundsdottir S, Stefansson OA, Rantapää-Dahlqvist S, Sonderby IE, Didriksen M, Stridh P, Haavik J, Tryggvadottir L, Frei O, Walters GB, Kockum I, Hjalgrim H, Olafsdottir TA, Selbaek G, Nyegaard M, Erikstrup C, Brodersen T, Saevarsdottir S, Olsson T, Nielsen KR, Haraldsson A, Bruun MT, Hansen TF; DBDS Genomic Consortium; Steingrimsdottir T, Jacobsen RL, Lie RT, Djurovic S, Alfredsson L, Lopez de Lapuente Portilla A, Brunak S, Melsted P, Halldorsson BV, Saemundsdottir J, Magnusson OT, Padyukov L, Banasik K, Rafnar T, Askling J, Klareskog L, Pedersen OB, Masson G, Havdahl A, Nilsson B, Andreassen OA, Daly M, Ostrowski SR, Jonsdottir I, Stefansson H, Holm H, Helgason A, Thorsteinsdottir U, Stefansson K, Gudbjartsson DF. Oddsson A, et al. Nat Commun. 2023 Jul 3;14(1):3923. doi: 10.1038/s41467-023-39492-4. Nat Commun. 2023. PMID: 37400429 Free PMC article. No abstract available.
Omicron Variant-Specific Serological Imprinting Following BA.1 or BA.4/5 Bivalent Vaccination and Previous SARS-CoV-2 Infection: A Cohort Study.
Baerends EAM, Reekie J, Andreasen SR, Stærke NB, Raben D, Nielsen H, Petersen KT, Johansen IS, Lindvig SO, Madsen LW, Wiese L, Iversen MB, Benfield T, Iversen KK, Larsen FD, Andersen SD, Juhl AK, Dietz LL, Hvidt AK, Ostrowski SR, Krause TG, Østergaard L, Søgaard OS, Lundgren J, Tolstrup M. Baerends EAM, et al. Clin Infect Dis. 2023 Nov 30;77(11):1511-1520. doi: 10.1093/cid/ciad402. Clin Infect Dis. 2023. PMID: 37392436 Free PMC article.
Elevated Levels of Interleukin-1β and Interleukin-10 Are Associated With Faster Lung Function Decline in People With Well-Treated Human Immunodeficiency Virus.
Thudium RF, Arentoft NS, Hoel H, Afzal S, von Stemann JH, Forman JL, Wilcke JT, Benfield T, Trøseid M, Borges ÁH, Ostrowski SR, Vestbo J, Kunisaki KM, Jensen JS, Nielsen SD. Thudium RF, et al. J Infect Dis. 2023 Oct 18;228(8):1080-1088. doi: 10.1093/infdis/jiad233. J Infect Dis. 2023. PMID: 37366576
Association of Self-reported Systemic Reactions Following SARS-CoV-2 Vaccination With Immunological Response in the Danish National Cohort Study of Effectiveness and Safety of SARS-CoV-2 Vaccines (ENFORCE).
Bannister WP, Raben D, Valentiner-Branth P, Tolstrup M, Larsen L, Tarp B, Brouw Iversen M, Schmeltz Søgaard O, Rye Ostrowski S, Breinholt Stærke N, Jakobsen ML, Olaf Lindvig S, Ruwald Juhl M, Somuncu Johansen I, Mustafa AB, Østergaard L, Dam Larsen F, Surland Knudsen L, Klastrup V, Wiese L, Benfield T, Toft Petersen K, Iversen KK, Nielsen H, Reekie J, Lundgren J; ENFORCE Study Group. Bannister WP, et al. Open Forum Infect Dis. 2023 May 8;10(6):ofad248. doi: 10.1093/ofid/ofad248. eCollection 2023 Jun. Open Forum Infect Dis. 2023. PMID: 37351453 Free PMC article.
Humoral and cellular immune responses eleven months after the third dose of BNT162b2 an mRNA-based COVID-19 vaccine in people with HIV - a prospective observational cohort study.
Heftdal LD, Pérez-Alós L, Hasselbalch RB, Hansen CB, Hamm SR, Møller DL, Pries-Heje M, Fogh K, Gerstoft J, Grønbæk K, Ostrowski SR, Frikke-Schmidt R, Sørensen E, Hilsted L, Bundgaard H, Garred P, Iversen K, Sabin C, Nielsen SD. Heftdal LD, et al. EBioMedicine. 2023 Jul;93:104661. doi: 10.1016/j.ebiom.2023.104661. Epub 2023 Jun 16. EBioMedicine. 2023. PMID: 37331161 Free PMC article.
Two Novel Human Leukocyte Antigen Alleles Are Associated with Decreased Risk of Onychomycosis in a Large Cohort of Danish Blood Donors.
Lindsø Andersen P, Jemec GBE, Erikstrup C, Didriksen M, Dinh KM, Mikkelsen S, Bruun MT, Hjalgrim H, Hansen TF, Sækmose SG, Ostrowski SR, Pedersen OB, Saunte DM. Lindsø Andersen P, et al. Skin Appendage Disord. 2023 Jun;9(3):195-202. doi: 10.1159/000529092. Epub 2023 Feb 15. Skin Appendage Disord. 2023. PMID: 37325286
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality.
Oddsson A, Sulem P, Sveinbjornsson G, Arnadottir GA, Steinthorsdottir V, Halldorsson GH, Atlason BA, Oskarsson GR, Helgason H, Nielsen HS, Westergaard D, Karjalainen JM, Katrinardottir H, Fridriksdottir R, Jensson BO, Tragante V, Ferkingstad E, Jonsson H, Gudjonsson SA, Beyter D, Moore KHS, Thordardottir HB, Kristmundsdottir S, Stefansson OA, Rantapää-Dahlqvist S, Sonderby IE, Didriksen M, Stridh P, Haavik J, Tryggvadottir L, Frei O, Walters GB, Kockum I, Hjalgrim H, Olafsdottir TA, Selbaek G, Nyegaard M, Erikstrup C, Brodersen T, Saevarsdottir S, Olsson T, Nielsen KR, Haraldsson A, Bruun MT, Hansen TF; DBDS Genomic Consortium; Steingrimsdottir T, Jacobsen RL, Lie RT, Djurovic S, Alfredsson L, Lopez de Lapuente Portilla A, Brunak S, Melsted P, Halldorsson BV, Saemundsdottir J, Magnusson OT, Padyukov L, Banasik K, Rafnar T, Askling J, Klareskog L, Pedersen OB, Masson G, Havdahl A, Nilsson B, Andreassen OA, Daly M, Ostrowski SR, Jonsdottir I, Stefansson H, Holm H, Helgason A, Thorsteinsdottir U, Stefansson K, Gudbjartsson DF. Oddsson A, et al. Nat Commun. 2023 Jun 10;14(1):3453. doi: 10.1038/s41467-023-38951-2. Nat Commun. 2023. PMID: 37301908 Free PMC article.
The differentiating effect of COVID-19-associated stress on the morbidity of blood donors with symptoms of hidradenitis suppurativa, hyperhidrosis, or psoriasis.
Henning MAS, Didriksen M, Ibler KS, Ostrowski SR, Erikstrup C, Nielsen K, Sækmose SG, Hansen TF, Ullum H, Thørner LW, Kaspersen KA, Mikkelsen S, Jemec GBE, Pedersen OB. Henning MAS, et al. Qual Life Res. 2023 Oct;32(10):2925-2937. doi: 10.1007/s11136-023-03448-4. Epub 2023 Jun 3. Qual Life Res. 2023. PMID: 37270451 Free PMC article.
Deep integrative models for large-scale human genomics.
Sigurdsson AI, Louloudis I, Banasik K, Westergaard D, Winther O, Lund O, Ostrowski SR, Erikstrup C, Pedersen OBV, Nyegaard M; DBDS Genomic Consortium; Brunak S, Vilhjálmsson BJ, Rasmussen S. Sigurdsson AI, et al. Nucleic Acids Res. 2023 Jul 7;51(12):e67. doi: 10.1093/nar/gkad373. Nucleic Acids Res. 2023. PMID: 37224538 Free PMC article.
Population-Based Characterization of Menstrual Migraine and Proposed Diagnostic Criteria.
Chalmer MA, Kogelman LJA, Ullum H, Sørensen E, Didriksen M, Mikkelsen S, Dinh KM, Brodersen T, Nielsen KR, Bruun MT, Banasik K, Brunak S, Erikstrup C, Pedersen OB, Ostrowski SR, Olesen J, Hansen TF. Chalmer MA, et al. JAMA Netw Open. 2023 May 1;6(5):e2313235. doi: 10.1001/jamanetworkopen.2023.13235. JAMA Netw Open. 2023. PMID: 37184838 Free article.
Author Correction: Genetic effects on the timing of parturition and links to fetal birth weight.
Solé-Navais P, Flatley C, Steinthorsdottir V, Vaudel M, Juodakis J, Chen J, Laisk T, LaBella AL, Westergaard D, Bacelis J, Brumpton B, Skotte L, Borges MC, Helgeland Ø, Mahajan A, Wielscher M, Lin F, Briggs C, Wang CA, Moen GH, Beaumont RN, Bradfield JP, Abraham A, Thorleifsson G, Gabrielsen ME, Ostrowski SR, Modzelewska D, Nohr EA, Hypponen E, Srivastava A, Talbot O, Allard C, Williams SM, Menon R, Shields BM, Sveinbjornsson G, Xu H, Melbye M, Lowe W Jr, Bouchard L, Oken E, Pedersen OB, Gudbjartsson DF, Erikstrup C, Sørensen E; Early Growth Genetics Consortium; Estonian Biobank Research Team; Danish Blood Donor Study Genomic Consortium; Lie RT, Teramo K, Hallman M, Juliusdottir T, Hakonarson H, Ullum H, Hattersley AT, Sletner L, Merialdi M, Rifas-Shiman SL, Steingrimsdottir T, Scholtens D, Power C, West J, Nyegaard M, Capra JA, Skogholt AH, Magnus P, Andreassen OA, Thorsteinsdottir U, Grant SFA, Qvigstad E, Pennell CE, Hivert MF, Hayes GM, Jarvelin MR, McCarthy MI, Lawlor DA, Nielsen HS, Mägi R, Rokas A, Hveem K, Stefansson K, Feenstra B, Njolstad P, Muglia LJ, Freathy RM, Johansson S, Zhang G, Jacobsson B. Solé-Navais P, et al. Nat Genet. 2023 Jul;55(7):1250. doi: 10.1038/s41588-023-01412-z. Nat Genet. 2023. PMID: 37165137 Free PMC article. No abstract available.
Humoral and cellular immune responses after three or four doses of BNT162b2 in patients with hematological malignancies.
Heftdal LD, Hamm SR, Pérez-Alós L, Madsen JR, Armenteros JJA, Fogh K, Kronborg CC, Vallentin AP, Hasselbalch RB, Møller DL, Hansen CB, Pries-Heje M, Gang AO, Ostrowski SR, Frikke-Schmidt R, Sørensen E, Hilsted L, Bundgaard H, Iversen K, Garred P, Nielsen SD, Grønbaek K. Heftdal LD, et al. Eur J Haematol. 2023 Aug;111(2):229-239. doi: 10.1111/ejh.13986. Epub 2023 May 8. Eur J Haematol. 2023. PMID: 37151174
Impact of age and comorbidities on SARS-CoV-2 vaccine-induced T cell immunity.
Dietz LL, Juhl AK, Søgaard OS, Reekie J, Nielsen H, Johansen IS, Benfield T, Wiese L, Stærke NB, Jensen TØ, Jakobsen SF, Olesen R, Iversen K, Fogh K, Bodilsen J, Petersen KT, Larsen L, Madsen LW, Lindvig SO, Holden IK, Raben D, Andersen SD, Hvidt AK, Andreasen SR, Baerends EAM, Lundgren J, Østergaard L, Tolstrup M; ENFORCE Study Group. Dietz LL, et al. Commun Med (Lond). 2023 Apr 24;3(1):58. doi: 10.1038/s43856-023-00277-x. Commun Med (Lond). 2023. PMID: 37095240 Free PMC article.
Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study.
Yu Chen H, Dina C, Small AM, Shaffer CM, Levinson RT, Helgadóttir A, Capoulade R, Munter HM, Martinsson A, Cairns BJ, Trudsø LC, Hoekstra M, Burr HA, Marsh TW, Damrauer SM, Dufresne L, Le Scouarnec S, Messika-Zeitoun D, Ranatunga DK, Whitmer RA, Bonnefond A, Sveinbjornsson G, Daníelsen R, Arnar DO, Thorgeirsson G, Thorsteinsdottir U, Gudbjartsson DF, Hólm H, Ghouse J, Olesen MS, Christensen AH, Mikkelsen S, Jacobsen RL, Dowsett J, Pedersen OBV, Erikstrup C, Ostrowski SR; Regeneron Genetics Center; O'Donnell CJ, Budoff MJ, Gudnason V, Post WS, Rotter JI, Lathrop M, Bundgaard H, Johansson B, Ljungberg J, Näslund U, Le Tourneau T, Smith JG, Wells QS, Söderberg S, Stefánsson K, Schott JJ, Rader DJ, Clarke R, Engert JC, Thanassoulis G. Yu Chen H, et al. Eur Heart J. 2023 Jun 1;44(21):1927-1939. doi: 10.1093/eurheartj/ehad142. Eur Heart J. 2023. PMID: 37038246 Free PMC article.
Genetic effects on the timing of parturition and links to fetal birth weight.
Solé-Navais P, Flatley C, Steinthorsdottir V, Vaudel M, Juodakis J, Chen J, Laisk T, LaBella AL, Westergaard D, Bacelis J, Brumpton B, Skotte L, Borges MC, Helgeland Ø, Mahajan A, Wielscher M, Lin F, Briggs C, Wang CA, Moen GH, Beaumont RN, Bradfield JP, Abraham A, Thorleifsson G, Gabrielsen ME, Ostrowski SR, Modzelewska D, Nohr EA, Hypponen E, Srivastava A, Talbot O, Allard C, Williams SM, Menon R, Shields BM, Sveinbjornsson G, Xu H, Melbye M, Lowe W Jr, Bouchard L, Oken E, Pedersen OB, Gudbjartsson DF, Erikstrup C, Sørensen E; Early Growth Genetics Consortium; Estonian Biobank Research Team; Danish Blood Donor Study Genomic Consortium; Lie RT, Teramo K, Hallman M, Juliusdottir T, Hakonarson H, Ullum H, Hattersley AT, Sletner L, Merialdi M, Rifas-Shiman SL, Steingrimsdottir T, Scholtens D, Power C, West J, Nyegaard M, Capra JA, Skogholt AH, Magnus P, Andreassen OA, Thorsteinsdottir U, Grant SFA, Qvigstad E, Pennell CE, Hivert MF, Hayes GM, Jarvelin MR, McCarthy MI, Lawlor DA, Nielsen HS, Mägi R, Rokas A, Hveem K, Stefansson K, Feenstra B, Njolstad P, Muglia LJ, Freathy RM, Johansson S, Zhang G, Jacobsson B. Solé-Navais P, et al. Nat Genet. 2023 Apr;55(4):559-567. doi: 10.1038/s41588-023-01343-9. Epub 2023 Apr 3. Nat Genet. 2023. PMID: 37012456 Free PMC article.
Developmental language disorder - a comprehensive study of more than 46,000 individuals.
Nudel R, Christensen RV, Kalnak N, Schwinn M, Banasik K, Dinh KM; DBDS Genomic Consortium; Erikstrup C, Pedersen OB, Burgdorf KS, Ullum H, Ostrowski SR, Hansen TF, Werge T. Nudel R, et al. Psychiatry Res. 2023 May;323:115171. doi: 10.1016/j.psychres.2023.115171. Epub 2023 Mar 16. Psychiatry Res. 2023. PMID: 36963307 Free article.
Sex differences in clinical characteristics of migraine and its burden: a population-based study.
Chalmer MA, Kogelman LJA, Callesen I, Christensen CG, Techlo TR, Møller PL, Davidsson OB, Olofsson IA, Schwinn M, Mikkelsen S, Dinh KM, Nielsen K, Topholm M, Erikstrup C, Ostrowski SR, Pedersen OB; DBDS Genomic Consortium; Hjalgrim H, Banasik K, Burgdorf KS, Nyegaard M, Olesen J, Hansen TF. Chalmer MA, et al. Eur J Neurol. 2023 Jun;30(6):1774-1784. doi: 10.1111/ene.15778. Epub 2023 Mar 26. Eur J Neurol. 2023. PMID: 36905094
Symptoms of attention deficit hyperactivity disorder are associated with Hidradenitis suppurativa in Danish blood donors.
Lindsø Andersen P, Villumsen B, Saunte DML, Burgdorf KS, Didriksen M, Ostrowski SR, Thørner LW, Erikstrup C, Dinh KM, Nielsen KR, Brodersen T, Bruun MT, Banasik K, Hansen TF, Pedersen OB, Jemec GB. Lindsø Andersen P, et al. Arch Dermatol Res. 2023 Sep;315(7):1989-1994. doi: 10.1007/s00403-023-02570-0. Epub 2023 Mar 3. Arch Dermatol Res. 2023. PMID: 36867221
Cluster headache polygenetic risk and known functional variants of CYP3A4 are not associated with treatment response.
Petersen AS, Barloese M, Lund N, Pedersen AF, Søborg MK, Chalmer MA, Callesen I, Winsvold BS, Zwart JA; DBDS Genomic Consortium; Ostrowski SR, Pedersen OB, Sellebjerg F, Søndergaard HB, Hansen MB, Jensen RH, Hansen TF. Petersen AS, et al. Eur J Neurol. 2023 May;30(5):1425-1434. doi: 10.1111/ene.15736. Epub 2023 Mar 2. Eur J Neurol. 2023. PMID: 36773010
Genetic variants associated with syncope implicate neural and autonomic processes.
Aegisdottir HM, Thorolfsdottir RB, Sveinbjornsson G, Stefansson OA, Gunnarsson B, Tragante V, Thorleifsson G, Stefansdottir L, Thorgeirsson TE, Ferkingstad E, Sulem P, Norddahl G, Rutsdottir G, Banasik K, Christensen AH, Mikkelsen C, Pedersen OB, Brunak S, Bruun MT, Erikstrup C, Jacobsen RL, Nielsen KR, Sørensen E, Frigge ML, Hjorleifsson KE, Ivarsdottir EV, Helgadottir A, Gretarsdottir S, Steinthorsdottir V, Oddsson A, Eggertsson HP, Halldorsson GH, Jones DA, Anderson JL, Knowlton KU, Nadauld LD; DBDS Genomic Consortium; Haraldsson M, Thorgeirsson G, Bundgaard H, Arnar DO, Thorsteinsdottir U, Gudbjartsson DF, Ostrowski SR, Holm H, Stefansson K. Aegisdottir HM, et al. Eur Heart J. 2023 Mar 21;44(12):1070-1080. doi: 10.1093/eurheartj/ehad016. Eur Heart J. 2023. PMID: 36747475
Cell-free fetal DNA for genetic evaluation in Copenhagen Pregnancy Loss Study (COPL): a prospective cohort study.
Schlaikjær Hartwig T, Ambye L, Gruhn JR, Petersen JF, Wrønding T, Amato L, Chi-Ho Chan A, Ji B, Bro-Jørgensen MH, Werge L, Petersen MMBS, Brinkmann C, Petersen JB, Dunø M, Bache I, Herrgård MJ, Jørgensen FS, Hoffmann ER, Nielsen HS; COPL consortium. Schlaikjær Hartwig T, et al. Lancet. 2023 Mar 4;401(10378):762-771. doi: 10.1016/S0140-6736(22)02610-1. Epub 2023 Feb 2. Lancet. 2023. PMID: 36739882
Humoral and T-cell response 12 months after the first BNT162b2 vaccination in solid organ transplant recipients and controls: Kinetics, associated factors, and role of SARS-CoV-2 infection.
Rezahosseini O, Hamm SR, Heftdal LD, Pérez-Alós L, Møller DL, Perch M, Madsen JR, Hald A, Hansen CB, Armenteros JJA, Pries-Heje MM, Hasselbalch RB, Fogh K, Frikke-Schmidt R, Hilsted LM, Sørensen E, Ostrowski SR, Harboe ZB, Iversen K, Bundgaard H, Sørensen SS, Rasmussen A, Garred P, Nielsen SD. Rezahosseini O, et al. Front Immunol. 2023 Jan 13;13:1075423. doi: 10.3389/fimmu.2022.1075423. eCollection 2022. Front Immunol. 2023. PMID: 36713395 Free PMC article.
Waning humoral and cellular immunity after COVID-19 vaccination in patients with psoriasis treated with methotrexate and biologics: a cohort study.
Kvist-Hansen A, Pérez-Alós L, Al-Sofi RF, Heftdal LD, Hamm SR, Møller DL, Pries-Heje MM, Fogh K, Hansen CB, Hasselbalch RB, Madsen JR, Armenteros JJA, Frikke-Schmidt R, Hilsted L, Sørensen E, Ostrowski SR, Bundgaard H, Nielsen SD, Iversen K, Zachariae C, Garred P, Skov L. Kvist-Hansen A, et al. Br J Dermatol. 2023 Apr 20;188(5):661-669. doi: 10.1093/bjd/ljad023. Br J Dermatol. 2023. PMID: 36703193
High titers of neutralizing SARS-CoV-2 antibodies six months after symptom onset are associated with increased severity in COVID-19 hospitalized patients.
Sejdic A, Frische A, Jørgensen CS, Rasmussen LD, Trebbien R, Dungu A, Holler JG, Ostrowski SR, Eriksson R, Søborg C, Nielsen TL, Fischer TK, Lindegaard B, Franck KT, Harboe ZB. Sejdic A, et al. Virol J. 2023 Jan 25;20(1):14. doi: 10.1186/s12985-023-01974-8. Virol J. 2023. PMID: 36698135 Free PMC article.
Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism.
Ghouse J, Tragante V, Ahlberg G, Rand SA, Jespersen JB, Leinøe EB, Vissing CR, Trudsø L, Jonsdottir I, Banasik K, Brunak S, Ostrowski SR, Pedersen OB, Sørensen E, Erikstrup C, Bruun MT, Nielsen KR, Køber L, Christensen AH, Iversen K, Jones D, Knowlton KU, Nadauld L, Halldorsson GH, Ferkingstad E, Olafsson I, Gretarsdottir S, Onundarson PT, Sulem P, Thorsteinsdottir U, Thorgeirsson G, Gudbjartsson DF, Stefansson K, Holm H, Olesen MS, Bundgaard H. Ghouse J, et al. Nat Genet. 2023 Mar;55(3):399-409. doi: 10.1038/s41588-022-01286-7. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36658437
Persistent Symptoms and Sequelae After Severe Acute Respiratory Syndrome Coronavirus 2 Infection Not Requiring Hospitalization: Results From Testing Denmark, a Danish Cross-sectional Survey.
van Wijhe M, Fogh K, Ethelberg S, Karmark Iversen K, Nielsen H, Østergaard L, Andersen B, Bundgaard H, Jørgensen CS, Scharff BFS, Ellermann-Eriksen S, Johansen IS, Fomsgaard A, Grove Krause T, Wiese L, Fischer TK, Mølbak K, Benfield T, Folke F, Lippert F, Ostrowski SR, Koch A, Erikstrup C, Vangsted AM, Sørensen AIV, Ullum H, Skov RL, Simonsen L, Nielsen SD. van Wijhe M, et al. Open Forum Infect Dis. 2022 Dec 21;10(1):ofac679. doi: 10.1093/ofid/ofac679. eCollection 2023 Jan. Open Forum Infect Dis. 2022. PMID: 36628054 Free PMC article.
A Cross-Sectional Study of SARS-CoV-2 Antibodies and Risk Factors for Seropositivity in Staff in Day Care Facilities and Preschools in Denmark.
Fogh K, Eriksen ARR, Larsen TG, Hasselbalch RB, Bundgaard H, Scharff BFSS, Nielsen SD, Jørgensen CS, Erikstrup C, Østergaard L, Ellermann-Eriksen S, Andersen B, Nielsen H, Johansen IS, Wiese L, Hindhede L, Mikkelsen S, Sækmose SG, Aagaard B, Holm DK, Harritshøj L, Simonsen L, Fischer TK, Folke F, Lippert F, Ostrowski SR, Benfield T, Mølbak K, Ethelberg S, Koch A, Vangsted AM, Krause TG, Fomsgaard A, Ullum H, Skov R, Iversen K. Fogh K, et al. Microbiol Spectr. 2023 Feb 14;11(1):e0417422. doi: 10.1128/spectrum.04174-22. Epub 2022 Dec 22. Microbiol Spectr. 2023. PMID: 36546864 Free PMC article.
Smoking is associated with infection risk in healthy blood donors.
Kjerulff B, Kaspersen KA, Dinh KM, Boldsen J, Mikkelsen S, Erikstrup LT, Sørensen E, Nielsen KR, Bruun MT, Hjalgrim H, Pedersen OB, Thørner LW, Ullum H, Ostrowski SR, Rostgaard K, Pedersen CB, Sigsgaard T, Erikstrup C. Kjerulff B, et al. Clin Microbiol Infect. 2023 Apr;29(4):506-514. doi: 10.1016/j.cmi.2022.10.020. Epub 2022 Nov 14. Clin Microbiol Infect. 2023. PMID: 36404421 Free article.
Prevalence of major depressive disorder in 51,658 otherwise healthy adult Danes: Sex differences in symptomatology and prediction of future anti-depressive medication.
Mikkelsen C, Larsen MAH, Sørensen E, Hansen TF, Mikkelsen S, Erikstrup C, Nielsen KR, Bruun MT, Hjalgrim H, Kessing LV, Werge T, Ullum H, Ostrowski SR, Pedersen OB, Thørner LW, Didriksen M. Mikkelsen C, et al. Psychiatry Res. 2022 Dec;318:114944. doi: 10.1016/j.psychres.2022.114944. Epub 2022 Nov 12. Psychiatry Res. 2022. PMID: 36402070 Free article.
Human leukocyte antigen system associations in Malassezia-related skin diseases.
Lindsø Andersen P, Jemec GB, Erikstrup C, Didriksen M, Dinh KM, Mikkelsen S, Sørensen E; DBDS Genetic Consortium; Nielsen KR, Bruun MT, Hjalgrim H, Hansen TF, Sækmose SG, Ostrowski SR, Saunte DML, Pedersen OB. Lindsø Andersen P, et al. Arch Dermatol Res. 2023 May;315(4):895-902. doi: 10.1007/s00403-022-02454-9. Epub 2022 Nov 17. Arch Dermatol Res. 2023. PMID: 36394635
Genome-wide association meta-analysis of knee and hip osteoarthritis uncovers genetic differences between patients treated with joint replacement and patients without joint replacement.
Henkel C, Styrkársdóttir U, Thorleifsson G, Stefánsdóttir L, Björnsdóttir G, Banasik K, Brunak S, Erikstrup C, Dinh KM, Hansen TF, Nielsen KR, Bruun MT, Dowsett J, Brodersen T; DBDS Genomic Consortium; Thorgeirsson TE, Gromov K, Boesen MP, Ullum H, Ostrowski SR, Pedersen OB, Stefánsson K, Troelsen A. Henkel C, et al. Ann Rheum Dis. 2023 Mar;82(3):384-392. doi: 10.1136/ard-2022-223199. Epub 2022 Nov 14. Ann Rheum Dis. 2023. PMID: 36376028
Multiomics study of nonalcoholic fatty liver disease.
Sveinbjornsson G, Ulfarsson MO, Thorolfsdottir RB, Jonsson BA, Einarsson E, Gunnlaugsson G, Rognvaldsson S, Arnar DO, Baldvinsson M, Bjarnason RG; DBDS Genomic consortium; Eiriksdottir T, Erikstrup C, Ferkingstad E, Halldorsson GH, Helgason H, Helgadottir A, Hindhede L, Hjorleifsson G, Jones D, Knowlton KU, Lund SH, Melsted P, Norland K, Olafsson I, Olafsson S, Oskarsson GR, Ostrowski SR, Pedersen OB, Snaebjarnarson AS, Sigurdsson E, Steinthorsdottir V, Schwinn M, Thorgeirsson G, Thorleifsson G, Jonsdottir I, Bundgaard H, Nadauld L, Bjornsson ES, Rulifson IC, Rafnar T, Norddahl GL, Thorsteinsdottir U, Sulem P, Gudbjartsson DF, Holm H, Stefansson K. Sveinbjornsson G, et al. Nat Genet. 2022 Nov;54(11):1652-1663. doi: 10.1038/s41588-022-01199-5. Epub 2022 Oct 24. Nat Genet. 2022. PMID: 36280732 Free PMC article.
A large cohort study of the effects of Lewis, ABO, 13 other blood groups, and secretor status on COVID-19 susceptibility, severity, and long COVID-19.
Moslemi C, Saekmose S, Larsen R, Brodersen T, Didriksen M, Hjalgrim H, Banasik K, Nielsen KR, Bruun MT, Dowsett J, Kasperen KA, Mikkelsen S, Hansen TF, Ullum H, Erikstrup C, Olsson ML, Ostrowski SR, Pedersen OB. Moslemi C, et al. Transfusion. 2023 Jan;63(1):47-58. doi: 10.1111/trf.17170. Epub 2022 Nov 3. Transfusion. 2023. PMID: 36271437 Free PMC article.
Comparison of vaccine-induced antibody neutralization against SARS-CoV-2 variants of concern following primary and booster doses of COVID-19 vaccines.
Hvidt AK, Baerends EAM, Søgaard OS, Stærke NB, Raben D, Reekie J, Nielsen H, Johansen IS, Wiese L, Benfield TL, Iversen KK, Mustafa AB, Juhl MR, Petersen KT, Ostrowski SR, Lindvig SO, Rasmussen LD, Schleimann MH, Andersen SD, Juhl AK, Dietz LL, Andreasen SR, Lundgren J, Østergaard L, Tolstrup M; ENFORCE Study Group. Hvidt AK, et al. Front Med (Lausanne). 2022 Oct 3;9:994160. doi: 10.3389/fmed.2022.994160. eCollection 2022. Front Med (Lausanne). 2022. PMID: 36262278 Free PMC article.
Genetic Variants Close to TTN, NKX2-5, and MYH6 Associate With AVNRT.
Andreasen L, Ahlberg G, Ægisdottir HM, Sveinbjörnsson G, Lundegaard PR, Hartmann JP, Paludan-Müller C, Hadji-Turdeghal K, Ghouse J, Pehrson S, Jensen HK, Riahi S, Hansen J, Sandgaard N, Sørensen E, Banasik K, Sækmose SG, Bruun MT, Hjalgrim H, Erikstrup C, Pedersen OB, Wittig M, Haunsø S, Ostrowski SR; DBDS Genomic Consortium; Franke A, Brunak S, Kanters JK, Ellervik C, Bundgaard H, Ullum H, Gudbjartsson DF, Thorsteinsdottir U, Holm H, Arnar DO, Stefansson K, Svendsen JH, Olesen MS. Andreasen L, et al. Circ Res. 2022 Oct 28;131(10):862-865. doi: 10.1161/CIRCRESAHA.122.321556. Epub 2022 Oct 7. Circ Res. 2022. PMID: 36205134 No abstract available.
Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis.
Hindy G, Tyrrell DJ, Vasbinder A, Wei C, Presswalla F, Wang H, Blakely P, Ozel AB, Graham S, Holton GH, Dowsett J, Fahed AC, Amadi KM, Erne GK, Tekmulla A, Ismail A, Launius C, Sotoodehnia N, Pankow JS, Thørner LW, Erikstrup C, Pedersen OB, Banasik K, Brunak S, Ullum H, Eugen-Olsen J, Ostrowski SR; DBDS Consortium; Haas ME, Nielsen JB, Lotta LA; Regeneron Genetics Center; Engström G, Melander O, Orho-Melander M, Zhao L, Murthy VL, Pinsky DJ, Willer CJ, Heckbert SR, Reiser J, Goldstein DR, Desch KC, Hayek SS. Hindy G, et al. J Clin Invest. 2022 Dec 15;132(24):e158788. doi: 10.1172/JCI158788. J Clin Invest. 2022. PMID: 36194491 Free PMC article.
Cohort Profile: The Danish Blood Donor Study.
Erikstrup C, Sørensen E, Nielsen KR, Bruun MT, Petersen MS, Rostgaard K, Thørner LW, Larsen M, Mikkelsen S, Dinh KM, Schwinn M, Rigas AS, Didriksen M, Dowsett J, von Stemann JH, Brodersen T, Paulsen IW, Hindhede L, Sækmose SG, Kaspersen KA, Boldsen JK, Kjerulff B, Werge T, Brunak S, Banasik K, Hansen TF, Ullum H, Hjalgrim H, Ostrowski SR, Pedersen OB. Erikstrup C, et al. Int J Epidemiol. 2023 Jun 6;52(3):e162-e171. doi: 10.1093/ije/dyac194. Int J Epidemiol. 2023. PMID: 36194120 Free PMC article. No abstract available.
A randomized placebo-controlled trial of convalescent plasma for adults hospitalized with COVID-19 pneumonia.
Thorlacius-Ussing L, Brooks PT, Nielsen H, Jensen BA, Wiese L, Sækmose SG, Johnsen S, Gybel-Brask M, Johansen IS, Bruun MT, Stærke NB, Østergaard L, Erikstrup C, Ostrowski SR, Homburg KM, Georgsen J, Mikkelsen S, Sandholdt H, Leding C, Hovmand N, Clausen CL, Tinggaard M, Pedersen KBH, Iversen KK, Tingsgård S, Israelsen SB, Benfield T. Thorlacius-Ussing L, et al. Sci Rep. 2022 Sep 30;12(1):16385. doi: 10.1038/s41598-022-19629-z. Sci Rep. 2022. PMID: 36180450 Free PMC article. Clinical Trial.
Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles: a Mendelian randomization analysis.
Helgadottir A, Thorleifsson G, Snaebjarnarson A, Stefansdottir L, Sveinbjornsson G, Tragante V, Björnsson E, Steinthorsdottir V, Gretarsdottir S, Helgason H, Saemundsdottir J, Olafsson I, Thune JJ, Raja AA, Ghouse J, Olesen MS, Christensen A, Jacobsen RL, Dowsett J, Bruun MT, Nielsen K, Knowlton K, Nadauld L, Benediktsson R, Erikstrup C, Pedersen OB, Banasik K, Brunak S; DBDS Genomic Consortium; Bundgaard H, Ostrowski SR, Sulem P, Arnar DO, Thorgeirsson G, Thorsteinsdottir U, Gudbjartsson DF, Stefansson K, Holm H. Helgadottir A, et al. Eur J Prev Cardiol. 2022 Dec 21;29(18):2374-2385. doi: 10.1093/eurjpc/zwac219. Eur J Prev Cardiol. 2022. PMID: 36125206
Early stimulated immune responses predict clinical disease severity in hospitalized COVID-19 patients.
Svanberg R, MacPherson C, Zucco A, Agius R, Faitova T, Andersen MA, da Cunha-Bang C, Gjærde LK, Møller MEE, Brooks PT, Lindegaard B, Sejdic A, Gang AO, Hersby DS, Brieghel C, Nielsen SD, Podlekareva D, Hald A, Bay JT, Marquart H, Lundgren J, Lebech AM, Helleberg M, Niemann CU, Ostrowski SR. Svanberg R, et al. Commun Med (Lond). 2022 Sep 12;2:114. doi: 10.1038/s43856-022-00178-5. eCollection 2022. Commun Med (Lond). 2022. PMID: 36101705 Free PMC article.
Cohort profile: Copenhagen Hospital Biobank - Cardiovascular Disease Cohort (CHB-CVDC): Construction of a large-scale genetic cohort to facilitate a better understanding of heart diseases.
Laursen IH, Banasik K, Haue AD, Petersen O, Holm PC, Westergaard D, Bundgaard H, Brunak S, Frikke-Schmidt R, Holm H, Sørensen E, Thørner LW, Larsen MAH, Schwinn M, Køber L, Torp-Pedersen C, Ostrowski SR, Erikstrup C, Nyegaard M, Stefánsson H, Gylfason A, Zink F, Walters GB, Oddsson A, Þorleifsson G, Másson G, Thorsteinsdottir U, Gudbjartsson D, Pedersen OB, Stefánsson K, Ullum H. Laursen IH, et al. BMJ Open. 2021 Dec 30;11(12):e049709. doi: 10.1136/bmjopen-2021-049709. BMJ Open. 2021. PMID: 36070241 Free PMC article.
Redefining germline predisposition in children with molecularly characterized ependymoma: a population-based 20-year cohort.
Foss-Skiftesvik J, Stoltze UK, van Overeem Hansen T, Ahlborn LB, Sørensen E, Ostrowski SR, Kullegaard SMA, Laspiur AO, Melchior LC, Scheie D, Kristensen BW, Skjøth-Rasmussen J, Schmiegelow K, Wadt K, Mathiasen R. Foss-Skiftesvik J, et al. Acta Neuropathol Commun. 2022 Aug 25;10(1):123. doi: 10.1186/s40478-022-01429-1. Acta Neuropathol Commun. 2022. PMID: 36008825 Free PMC article.
Seroprevalence and infection fatality rate of the SARS-CoV-2 Omicron variant in Denmark: A nationwide serosurveillance study.
Erikstrup C, Laksafoss AD, Gladov J, Kaspersen KA, Mikkelsen S, Hindhede L, Boldsen JK, Jørgensen SW, Ethelberg S, Holm DK, Bruun MT, Nissen J, Schwinn M, Brodersen T, Mikkelsen C, Sækmose SG, Sørensen E, Harritshøj LH, Aagaard B, Dinh KM, Busch MP, Jørgensen CS, Krause TG, Ullum H, Ostrowski SR, Espenhain L, Pedersen OBV. Erikstrup C, et al. Lancet Reg Health Eur. 2022 Oct;21:100479. doi: 10.1016/j.lanepe.2022.100479. Epub 2022 Aug 5. Lancet Reg Health Eur. 2022. PMID: 35959415 Free PMC article.
Levels of SARS-CoV-2 antibodies among fully vaccinated individuals with Delta or Omicron variant breakthrough infections.
Stærke NB, Reekie J, Nielsen H, Benfield T, Wiese L, Knudsen LS, Iversen MB, Iversen K, Fogh K, Bodilsen J, Juhl MR, Lindvig SO, Øvrehus A, Madsen LW, Klastrup V, Andersen SD, Juhl AK, Andreasen SR, Ostrowski SR, Erikstrup C, Fischer TK, Tolstrup M, Østergaard L, Johansen IS, Lundgren J, Søgaard OS. Stærke NB, et al. Nat Commun. 2022 Aug 1;13(1):4466. doi: 10.1038/s41467-022-32254-8. Nat Commun. 2022. PMID: 35915081 Free PMC article.
The sequences of 150,119 genomes in the UK Biobank.
Halldorsson BV, Eggertsson HP, Moore KHS, Hauswedell H, Eiriksson O, Ulfarsson MO, Palsson G, Hardarson MT, Oddsson A, Jensson BO, Kristmundsdottir S, Sigurpalsdottir BD, Stefansson OA, Beyter D, Holley G, Tragante V, Gylfason A, Olason PI, Zink F, Asgeirsdottir M, Sverrisson ST, Sigurdsson B, Gudjonsson SA, Sigurdsson GT, Halldorsson GH, Sveinbjornsson G, Norland K, Styrkarsdottir U, Magnusdottir DN, Snorradottir S, Kristinsson K, Sobech E, Jonsson H, Geirsson AJ, Olafsson I, Jonsson P, Pedersen OB, Erikstrup C, Brunak S, Ostrowski SR; DBDS Genetic Consortium; Thorleifsson G, Jonsson F, Melsted P, Jonsdottir I, Rafnar T, Holm H, Stefansson H, Saemundsdottir J, Gudbjartsson DF, Magnusson OT, Masson G, Thorsteinsdottir U, Helgason A, Jonsson H, Sulem P, Stefansson K. Halldorsson BV, et al. Nature. 2022 Jul;607(7920):732-740. doi: 10.1038/s41586-022-04965-x. Epub 2022 Jul 20. Nature. 2022. PMID: 35859178 Free PMC article.
IL-6 Autoantibodies Predict Lower Platelet Counts and Altered Plasma Cytokine Profiles in Healthy Blood Donors: Results From the Danish Blood Donor Study.
von Stemann JH, Pedersen OBV, Hjalgrim H, Erikstrup C, Ullum H, Dowsett J, Thørner LW, Larsen MAH, Sørensen E, Hansen MB, Ostrowski SR. von Stemann JH, et al. Front Med (Lausanne). 2022 Jun 24;9:914262. doi: 10.3389/fmed.2022.914262. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35814772 Free PMC article.
Antibody responses and risk factors associated with impaired immunological outcomes following two doses of BNT162b2 COVID-19 vaccination in patients with chronic pulmonary diseases.
Harboe ZB, Hamm SR, Pérez-Alós L, Sivapalan P, Priemé H, Wilcke T, Kjeldgaard P, Shaker S, Svorre Jordan A, Møller DL, Heftdal LD, Madsen JR, Bayarri-Olmos R, Hansen CB, Pries-Heje MM, Hasselbalch RB, Fogh K, Armenteros JJA, Hilsted L, Sørensen E, Lindegaard B, Browatzki A, Biering-Sørensen T, Frikke-Schmidt R, Ostrowski SR, Iversen KK, Bundgaard H, Nielsen SD, Garred P, Jensen JS. Harboe ZB, et al. BMJ Open Respir Res. 2022 Jul;9(1):e001268. doi: 10.1136/bmjresp-2022-001268. BMJ Open Respir Res. 2022. PMID: 35793836 Free PMC article.
SARS-CoV-2 antibody prevalence among homeless people and shelter workers in Denmark: a nationwide cross-sectional study.
Eriksen ARR, Fogh K, Hasselbalch RB, Bundgaard H, Nielsen SD, Jørgensen CS, Scharff BFSS, Erikstrup C, Sækmose SG, Holm DK, Aagaard B, Kristensen JH, Bødker CA, Norsk JB, Nielsen PB, Østergaard L, Ellermann-Eriksen S, Andersen B, Nielsen H, Johansen IS, Wiese L, Simonsen L, K Fischer T, Folke F, Lippert F, Ostrowski SR, Ethelberg S, Koch A, Vangsted AM, Krause T, Fomsgaard A, Nielsen C, Ullum H, Skov R, Iversen K. Eriksen ARR, et al. BMC Public Health. 2022 Jun 27;22(1):1261. doi: 10.1186/s12889-022-13642-7. BMC Public Health. 2022. PMID: 35761270 Free PMC article.
Polygenic risk score for ACE-inhibitor-associated cough based on the discovery of new genetic loci.
Ghouse J, Tragante V, Muhammad A, Ahlberg G, Skov MW, Roden DM, Jonsdottir I, Andreasen L, Lundegaard PR, Trudsø LC, Banasik K, Brunak S, Ostrowski SR; eMERGE consortium; Torp-Pedersen C, Pedersen OV, Sørensen E, Køber L, Iversen K, Thorsteinsdottir U, Thorgeirsson G, Ullum H, Gudbjartsson DF, Mosley JD, Holm H, Stefansson K, Bundgaard H, Olesen MS. Ghouse J, et al. Eur Heart J. 2022 Dec 1;43(45):4707-4718. doi: 10.1093/eurheartj/ehac322. Eur Heart J. 2022. PMID: 35751511 Free PMC article.
Low adherence to the guideline for the acute treatment of migraine.
Olesen A, Schytz HW, Ostrowski SR, Topholm M, Nielsen K, Erikstrup C, Mikkelsen S, Pedersen OB, Olesen J, Hansen TF, Chalmer MA. Olesen A, et al. Sci Rep. 2022 May 19;12(1):8487. doi: 10.1038/s41598-022-12545-2. Sci Rep. 2022. PMID: 35589944 Free PMC article.
Author Correction: Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology.
Bjornsdottir G, Stefansdottir L, Thorleifsson G, Sulem P, Norland K, Ferkingstad E, Oddsson A, Zink F, Lund SH, Nawaz MS, Bragi Walters G, Skuladottir AT, Gudjonsson SA, Einarsson G, Halldorsson GH, Bjarnadottir V, Sveinbjornsson G, Helgadottir A, Styrkarsdottir U, Gudmundsson LJ, Pedersen OB, Hansen TF, Werge T, Banasik K, Troelsen A, Skou ST, Thørner LW, Erikstrup C, Nielsen KR, Mikkelsen S; DBDS Genetic Consortium; GO Consortium; Jonsdottir I, Bjornsson A, Olafsson IH, Ulfarsson E, Blondal J, Vikingsson A, Brunak S, Ostrowski SR, Ullum H, Thorsteinsdottir U, Stefansson H, Gudbjartsson DF, Thorgeirsson TE, Stefansson K. Bjornsdottir G, et al. Nat Commun. 2022 Apr 27;13(1):2419. doi: 10.1038/s41467-022-30129-6. Nat Commun. 2022. PMID: 35477715 Free PMC article. No abstract available.
Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset.
Saevarsdottir S, Stefansdottir L, Sulem P, Thorleifsson G, Ferkingstad E, Rutsdottir G, Glintborg B, Westerlind H, Grondal G, Loft IC, Sorensen SB, Lie BA, Brink M, Ärlestig L, Arnthorsson AO, Baecklund E, Banasik K, Bank S, Bjorkman LI, Ellingsen T, Erikstrup C, Frei O, Gjertsson I, Gudbjartsson DF, Gudjonsson SA, Halldorsson GH, Hendricks O, Hillert J, Hogdall E, Jacobsen S, Jensen DV, Jonsson H, Kastbom A, Kockum I, Kristensen S, Kristjansdottir H, Larsen MH, Linauskas A, Hauge EM, Loft AG, Ludviksson BR, Lund SH, Markusson T, Masson G, Melsted P, Moore KHS, Munk H, Nielsen KR, Norddahl GL, Oddsson A, Olafsdottir TA, Olason PI, Olsson T, Ostrowski SR, Hørslev-Petersen K, Rognvaldsson S, Sanner H, Silberberg GN, Stefansson H, Sørensen E, Sørensen IJ, Turesson C, Bergman T, Alfredsson L, Kvien TK, Brunak S, Steinsson K, Andersen V, Andreassen OA, Rantapää-Dahlqvist S, Hetland ML, Klareskog L, Askling J, Padyukov L, Pedersen OB, Thorsteinsdottir U, Jonsdottir I, Stefansson K; Members of the DBDS Genomic Consortium; Danish RA Genetics Working Group; Swedish Rheumatology Quality Register Biobank Study Group (SRQb). Saevarsdottir S, et al. Ann Rheum Dis. 2022 Aug;81(8):1085-1095. doi: 10.1136/annrheumdis-2021-221754. Epub 2022 Apr 25. Ann Rheum Dis. 2022. PMID: 35470158 Free PMC article.
Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors.
Pérez-Alós L, Armenteros JJA, Madsen JR, Hansen CB, Jarlhelt I, Hamm SR, Heftdal LD, Pries-Heje MM, Møller DL, Fogh K, Hasselbalch RB, Rosbjerg A, Brunak S, Sørensen E, Larsen MAH, Ostrowski SR, Frikke-Schmidt R, Bayarri-Olmos R, Hilsted LM, Iversen KK, Bundgaard H, Nielsen SD, Garred P. Pérez-Alós L, et al. Nat Commun. 2022 Mar 28;13(1):1614. doi: 10.1038/s41467-022-29225-4. Nat Commun. 2022. PMID: 35347129 Free PMC article.
A genome-wide meta-analysis identifies 50 genetic loci associated with carpal tunnel syndrome.
Skuladottir AT, Bjornsdottir G, Ferkingstad E, Einarsson G, Stefansdottir L, Nawaz MS, Oddsson A, Olafsdottir TA, Saevarsdottir S, Walters GB, Magnusson SH, Bjornsdottir A, Sveinsson OA, Vikingsson A, Hansen TF, Jacobsen RL, Erikstrup C, Schwinn M, Brunak S, Banasik K, Ostrowski SR, Troelsen A, Henkel C, Pedersen OB; DBDS Genetic Consortium; Jonsdottir I, Gudbjartsson DF, Sulem P, Thorgeirsson TE, Stefansson H, Stefansson K. Skuladottir AT, et al. Nat Commun. 2022 Mar 24;13(1):1598. doi: 10.1038/s41467-022-29133-7. Nat Commun. 2022. PMID: 35332129 Free PMC article.
Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study.
Magnúsdóttir I, Lovik A, Unnarsdóttir AB, McCartney D, Ask H, Kõiv K, Christoffersen LAN, Johnson SU, Hauksdóttir A, Fawns-Ritchie C, Helenius D, González-Hijón J, Lu L, Ebrahimi OV, Hoffart A, Porteous DJ, Fang F, Jakobsdóttir J, Lehto K, Andreassen OA, Pedersen OBV, Aspelund T, Valdimarsdóttir UA; COVIDMENT Collaboration. Magnúsdóttir I, et al. Lancet Public Health. 2022 May;7(5):e406-e416. doi: 10.1016/S2468-2667(22)00042-1. Epub 2022 Mar 14. Lancet Public Health. 2022. PMID: 35298894 Free PMC article.
Characteristics associated with serological COVID-19 vaccine response and durability in an older population with significant comorbidity: the Danish Nationwide ENFORCE Study.
Søgaard OS, Reekie J, Johansen IS, Nielsen H, Benfield T, Wiese L, Stærke NB, Iversen K, Fogh K, Bodilsen J, Iversen M, Knudsen LS, Klastrup V, Larsen FD, Andersen SD, Hvidt AK, Andreasen SR, Madsen LW, Lindvig SO, Øvrehus A, Ostrowski SR, Abildgaard C, Matthews C, Jensen TO, Raben D, Erikstrup C, Fischer TK, Tolstrup M, Østergaard L, Lundgren J; ENFORCE Writing Group. Søgaard OS, et al. Clin Microbiol Infect. 2022 Aug;28(8):1126-1133. doi: 10.1016/j.cmi.2022.03.003. Epub 2022 Mar 11. Clin Microbiol Infect. 2022. PMID: 35283313 Free PMC article.
Decline in Antibody Concentration 6 Months After Two Doses of SARS-CoV-2 BNT162b2 Vaccine in Solid Organ Transplant Recipients and Healthy Controls.
Hamm SR, Møller DL, Pérez-Alós L, Hansen CB, Pries-Heje MM, Heftdal LD, Hasselbalch RB, Fogh K, Madsen JR, Almagro Armenteros JJ, Knudsen AD, Poulsen JR, Frikke-Schmidt R, Hilsted LM, Sørensen E, Ostrowski SR, Harboe ZB, Perch M, Sørensen SS, Rasmussen A, Bundgaard H, Garred P, Iversen K, Nielsen SD. Hamm SR, et al. Front Immunol. 2022 Feb 23;13:832501. doi: 10.3389/fimmu.2022.832501. eCollection 2022. Front Immunol. 2022. PMID: 35281023 Free PMC article.
The health-related quality of life in hyperhidrosis and co-morbidities.
Henning MAS, Ibler KS, Loft I, Ostrowski SR, Erikstrup C, Nielsen KR, Bruun MT, Ullum H, Didriksen M, Dinh KM, Pedersen OB, Jemec GBE. Henning MAS, et al. Qual Life Res. 2022 Aug;31(8):2331-2340. doi: 10.1007/s11136-022-03108-z. Epub 2022 Feb 22. Qual Life Res. 2022. PMID: 35192149
Seroprevalence of SARS-CoV-2 antibodies in social housing areas in Denmark.
Fogh K, Eriksen ARR, Hasselbalch RB, Kristensen ES, Bundgaard H, Nielsen SD, Jørgensen CS, Scharff BFSS, Erikstrup C, Sækmose SG, Holm DK, Aagaard B, Norsk J, Nielsen PB, Kristensen JH, Østergaard L, Ellermann-Eriksen S, Andersen B, Nielsen H, Johansen IS, Wiese L, Simonsen L, Fischer TK, Folke F, Lippert F, Ostrowski SR, Ethelberg S, Koch A, Vangsted AM, Krause TG, Fomsgaard A, Nielsen C, Ullum H, Skov R, Iversen K. Fogh K, et al. BMC Infect Dis. 2022 Feb 10;22(1):143. doi: 10.1186/s12879-022-07102-1. BMC Infect Dis. 2022. PMID: 35144550 Free PMC article.
Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology.
Bjornsdottir G, Stefansdottir L, Thorleifsson G, Sulem P, Norland K, Ferkingstad E, Oddsson A, Zink F, Lund SH, Nawaz MS, Bragi Walters G, Skuladottir AT, Gudjonsson SA, Einarsson G, Halldorsson GH, Bjarnadottir V, Sveinbjornsson G, Helgadottir A, Styrkarsdottir U, Gudmundsson LJ, Pedersen OB, Hansen TF, Werge T, Banasik K, Troelsen A, Skou ST, Thørner LW, Erikstrup C, Nielsen KR, Mikkelsen S; DBDS Genetic Consortium; GO Consortium; Jonsdottir I, Bjornsson A, Olafsson IH, Ulfarsson E, Blondal J, Vikingsson A, Brunak S, Ostrowski SR, Ullum H, Thorsteinsdottir U, Stefansson H, Gudbjartsson DF, Thorgeirsson TE, Stefansson K. Bjornsdottir G, et al. Nat Commun. 2022 Feb 2;13(1):634. doi: 10.1038/s41467-022-28167-1. Nat Commun. 2022. PMID: 35110524 Free PMC article.
Long-term detection of SARS-CoV-2 antibodies after infection and risk of re-infection.
Hønge BL, Hindhede L, Kaspersen KA, Harritshøj LH, Mikkelsen S, Holm DK, Nilsson AC, Sækmose SG, Sørensen E, Aagaard B, Hjalgrim H, Jørgensen CS, Krause TG, Ullum H, Pedersen OBV, Ostrowski SR, Erikstrup C. Hønge BL, et al. Int J Infect Dis. 2022 Mar;116:289-292. doi: 10.1016/j.ijid.2022.01.041. Epub 2022 Jan 22. Int J Infect Dis. 2022. PMID: 35077881 Free PMC article.
Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations.
Unnarsdóttir AB, Lovik A, Fawns-Ritchie C, Ask H, Kõiv K, Hagen K, Didriksen M, Christoffersen LAN, Garðarsson AB, McIntosh A, Kähler AK, Campbell A, Hauksdóttir A, Erikstrup C, Mikkelsen DH, Altschul D, Thordardottir EB, Frans EM, Kvale G, Tómasson G, Kariis HM, Jónsdóttir HL, Rúnarsdóttir H, Magnúsdóttir I, Eid J, Jakobsdóttir J, Nielsen KR, Kaspersen KA, Milani L, Trogstad LS, Yi L, Bruun MT, Sullivan PF, Magnus PM, Shen Q, Nesvåg R, Brandlistuen RE, Mägi R, Ostrowski SR, Løkhammer S, Solem S, Reichborn-Kjennerud T, Hansen TF, Werge T, Aspelund T, Porteous DJ, Fang F, Lehto K, Andreassen OA, Pedersen OBV, Hellard SL, Valdimarsdóttir UA. Unnarsdóttir AB, et al. Int J Epidemiol. 2022 Jun 13;51(3):e108-e122. doi: 10.1093/ije/dyab234. Int J Epidemiol. 2022. PMID: 35020900 Free PMC article. No abstract available.
Testing Denmark: a Danish Nationwide Surveillance Study of COVID-19.
Fogh K, Strange JE, Scharff BFSS, Eriksen ARR, Hasselbalch RB, Bundgaard H, Nielsen SD, Jørgensen CS, Erikstrup C, Norsk J, Nielsen PB, Kristensen JH, Østergaard L, Ellermann-Eriksen S, Andersen B, Nielsen H, Johansen IS, Wiese L, Simonsen L, Fischer TK, Folke F, Lippert F, Ostrowski SR, Benfield T, Mølbak K, Ethelberg S, Koch A, Sönksen UW, Vangsted AM, Krause TG, Fomsgaard A, Ullum H, Skov R, Iversen K. Fogh K, et al. Microbiol Spectr. 2021 Dec 22;9(3):e0133021. doi: 10.1128/Spectrum.01330-21. Epub 2021 Dec 15. Microbiol Spectr. 2021. PMID: 34908473 Free PMC article.
Humoral response to two doses of BNT162b2 vaccination in people with HIV.
Heftdal LD, Knudsen AD, Hamm SR, Hansen CB, Møller DL, Pries-Heje M, Fogh K, Hasselbalch RB, Jarlhelt I, Pérez-Alós L, Hilsted LM, Ostrowski SR, Gerstoft J, Grønbaek K, Bundgaard H, Iversen K, Garred P, Nielsen SD. Heftdal LD, et al. J Intern Med. 2022 Apr;291(4):513-518. doi: 10.1111/joim.13419. Epub 2021 Dec 16. J Intern Med. 2022. PMID: 34841629 Free PMC article.
Estimation of SARS-CoV-2 Infection Fatality Rate by Age and Comorbidity Status Using Antibody Screening of Blood Donors During the COVID-19 Epidemic in Denmark.
Kaspersen KA, Hindhede L, Boldsen JK, Mikkelsen S, Vestergaard LS, Berthelsen AN, Moustsen-Helms IR, Holm DK, Nilsson AC, Sækmose SG, Sørensen E, Harritshøj LH, Aagaard B, Hjalgrim H, Lillevang ST, Jørgensen CS, Krause TG, Ullum H, Pedersen OBV, Ostrowski SR, Erikstrup C. Kaspersen KA, et al. J Infect Dis. 2022 Jan 18;225(2):219-228. doi: 10.1093/infdis/jiab566. J Infect Dis. 2022. PMID: 34788834 Free PMC article.
Functional Effects of Receptor-Binding Domain Mutations of SARS-CoV-2 B.1.351 and P.1 Variants.
Bayarri-Olmos R, Jarlhelt I, Johnsen LB, Hansen CB, Helgstrand C, Rose Bjelke J, Matthiesen F, Nielsen SD, Iversen KK, Ostrowski SR, Bundgaard H, Frikke-Schmidt R, Garred P, Skjoedt MO. Bayarri-Olmos R, et al. Front Immunol. 2021 Oct 7;12:757197. doi: 10.3389/fimmu.2021.757197. eCollection 2021. Front Immunol. 2021. PMID: 34691078 Free PMC article. Clinical Trial.
Risk Factors for Being Seronegative following SARS-CoV-2 Infection in a Large Cohort of Health Care Workers in Denmark.
Johannesen CK, Rezahosseini O, Gybel-Brask M, Kristensen JH, Hasselbalch RB, Pries-Heje MM, Nielsen PB, Knudsen AD, Fogh K, Norsk JB, Andersen O, Jensen CAJ, Torp-Pedersen C, Rungby J, Ditlev SB, Hageman I, Møgelvang R, Dessau RB, Sørensen E, Harritshøj LH, Folke F, Sten C, Møller MEE, Engsig FN, Ullum H, Jørgensen CS, Ostrowski SR, Bundgaard H, Iversen KK, Fischer TK, Nielsen SD. Johannesen CK, et al. Microbiol Spectr. 2021 Oct 31;9(2):e0090421. doi: 10.1128/Spectrum.00904-21. Epub 2021 Oct 20. Microbiol Spectr. 2021. PMID: 34668738 Free PMC article.
A life course approach to understanding associations between natural environments and mental well-being for the Danish blood donor cohort.
Engemann K, Svenning JC, Arge L, Brandt J, Bruun MT, Didriksen M, Erikstrup C, Geels C, Hertel O, Horsdal HT, Kaspersen KA, Mikkelsen S, Mortensen PB, Nielsen KR, Ostrowski SR, Pedersen OB, Tsirogiannis C, Sabel CE, Sigsgaard T, Ullum H, Pedersen CB. Engemann K, et al. Health Place. 2021 Nov;72:102678. doi: 10.1016/j.healthplace.2021.102678. Epub 2021 Oct 2. Health Place. 2021. PMID: 34610547
Seroprevalence of SARS-CoV-2 antibodies and reduced risk of reinfection through 6 months: a Danish observational cohort study of 44 000 healthcare workers.
Iversen K, Kristensen JH, Hasselbalch RB, Pries-Heje M, Nielsen PB, Knudsen AD, Fogh K, Norsk JB, Andersen O, Fischer TK, Juul Jensen CA, Torp-Pedersen C, Rungby J, Ditlev SB, Hageman I, Møgelvang R, Gybel-Brask M, Dessau RB, Sørensen E, Harritshøj L, Folke F, Sten C, Engel Møller ME, Benfield T, Ullum H, Jørgensen CS, Erikstrup C, Ostrowski SR, Nielsen SD, Bundgaard H. Iversen K, et al. Clin Microbiol Infect. 2022 May;28(5):710-717. doi: 10.1016/j.cmi.2021.09.005. Epub 2021 Sep 17. Clin Microbiol Infect. 2022. PMID: 34543759 Free PMC article.
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY,… See abstract for full author list ➔ Bastard P, et al. Sci Immunol. 2021 Aug 19;6(62):eabl4340. doi: 10.1126/sciimmunol.abl4340. Sci Immunol. 2021. PMID: 34413139 Free PMC article.
Impact of COVID-19 Pandemic on Sleep Quality, Stress Level and Health-Related Quality of Life-A Large Prospective Cohort Study on Adult Danes.
Didriksen M, Werge T, Nissen J, Schwinn M, Sørensen E, Nielsen KR, Bruun MT, Banasik K, Hansen TF, Erikstrup C, Ostrowski SR, Jennum PJ, Hjalgrim H, Ullum H, Pedersen OB. Didriksen M, et al. Int J Environ Res Public Health. 2021 Jul 17;18(14):7610. doi: 10.3390/ijerph18147610. Int J Environ Res Public Health. 2021. PMID: 34300061 Free PMC article.
Antibody-dependent neutralizing capacity of the SARS-CoV-2 vaccine BNT162b2 with and without previous COVID-19 priming.
Hansen CB, Jarlhelt I, Hasselbalch RB, Hamm SR, Fogh K, Pries-Heje MM, Møller DL, Heftdal LD, Pérez-Alós L, Sørensen E, Larsen MAH, Skjoedt MO, Ostrowski SR, Frikke-Schmidt R, Bayarri-Olmos R, Hilsted LM, Bundgaard H, Nielsen SD, Iversen KK, Garred P. Hansen CB, et al. J Intern Med. 2021 Dec;290(6):1272-1274. doi: 10.1111/joim.13366. Epub 2021 Aug 2. J Intern Med. 2021. PMID: 34237190 Free PMC article. No abstract available.
Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients.
Bliddal S, Banasik K, Pedersen OB, Nissen J, Cantwell L, Schwinn M, Tulstrup M, Westergaard D, Ullum H, Brunak S, Tommerup N, Feenstra B, Geller F, Ostrowski SR, Grønbæk K, Nielsen CH, Nielsen SD, Feldt-Rasmussen U. Bliddal S, et al. Sci Rep. 2021 Jun 23;11(1):13153. doi: 10.1038/s41598-021-92045-x. Sci Rep. 2021. PMID: 34162913 Free PMC article.
Hyperhidrosis and the risk of being treated for skin infections.
Henning MAS, Ibler KS, Ostrowski SR, Erikstrup C, Nielsen KR, Bruun MT, Hjalgrim H, Ullum H, Didriksen M, Dinh KM, Rostgaard K, Pedersen OB, Jemec GB. Henning MAS, et al. J Dermatolog Treat. 2022 Jun;33(4):2263-2269. doi: 10.1080/09546634.2021.1944971. Epub 2021 Jul 5. J Dermatolog Treat. 2022. PMID: 34152896
Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor.
Dowsett J, Ferkingstad E, Rasmussen LJH, Thørner LW, Magnússon MK, Sugden K, Thorleifsson G, Frigge M, Burgdorf KS, Ostrowski SR, Sørensen E, Erikstrup C, Pedersen OB, Hansen TF, Banasik K, Brunak S; DBDS Genomic Consortium; Tragante V, Lund SH, Stefansdottir L, Gunnarson B, Poulton R, Arseneault L, Caspi A, Moffitt TE, Gudbjartsson D, Eugen-Olsen J, Stefánsson H, Stefánsson K, Ullum H. Dowsett J, et al. Commun Biol. 2021 Jun 2;4(1):655. doi: 10.1038/s42003-021-02144-8. Commun Biol. 2021. PMID: 34079037 Free PMC article.
ABO blood types and sepsis mortality.
Itenov TS, Sessler DI, Khanna AK, Ostrowski SR, Johansson PI, Erikstrup C, Pedersen OB, Rygård SL, Holst LB, Bestle MH, Hein L, Lindhardt A, Tousi H, Andersen MH, Mohr T, Lundgren JD, Jensen JU. Itenov TS, et al. Ann Intensive Care. 2021 Apr 20;11(1):61. doi: 10.1186/s13613-021-00844-2. Ann Intensive Care. 2021. PMID: 33877463 Free PMC article.
Functional immune reconstitution early after allogeneic haematopoietic cell transplantation: A comparison of pre- and post-transplantation cytokine responses in stimulated whole blood.
Gjaerde LK, Brooks PT, Andersen NS, Friis LS, Kornblit B, Petersen SL, Schjødt I, Nielsen SD, Ostrowski SR, Sengeløv H. Gjaerde LK, et al. Scand J Immunol. 2021 Jul;94(1):e13042. doi: 10.1111/sji.13042. Epub 2021 Apr 12. Scand J Immunol. 2021. PMID: 33772836 Free article.
Blood transfusion in major emergency abdominal surgery.
Schack A, Ekeloef S, Ostrowski SR, Gögenur I, Burcharth J. Schack A, et al. Eur J Trauma Emerg Surg. 2022 Feb;48(1):121-131. doi: 10.1007/s00068-020-01562-3. Epub 2021 Jan 2. Eur J Trauma Emerg Surg. 2022. PMID: 33388785
Prognostic Value of Soluble Urokinase-Type Plasminogen Activator Receptor and High-Sensitivity C-Reactive Protein on Postoperative Mortality in Patients Undergoing Elective On-Pump Cardiac Surgery.
Rasmussen SR, Nielsen RV, Eriksson F, Dons M, Vedel AG, Buggeskov KB, Møgelvang R, Ostrowski SR, Ravn HB. Rasmussen SR, et al. J Cardiothorac Vasc Anesth. 2021 Aug;35(8):2415-2423. doi: 10.1053/j.jvca.2020.10.049. Epub 2020 Nov 2. J Cardiothorac Vasc Anesth. 2021. PMID: 33243671
A randomised double-blind pilot trial comparing a mean arterial pressure target of 65 mm Hg versus 72 mm Hg after out-of-hospital cardiac arrest.
Grand J, Meyer AS, Kjaergaard J, Wiberg S, Thomsen JH, Frydland M, Ostrowski SR, Johansson PI, Hassager C. Grand J, et al. Eur Heart J Acute Cardiovasc Care. 2020 Nov;9(4_suppl):S100-S109. doi: 10.1177/2048872619900095. Epub 2020 Jan 31. Eur Heart J Acute Cardiovasc Care. 2020. PMID: 32004081 Clinical Trial.
"Endothelial Dysfunction in Resuscitated Cardiac Arrest (ENDO-RCA): Safety and efficacy of low-dose Iloprost, a prostacyclin analogue, in addition to standard therapy, as compared to standard therapy alone, in post-cardiac-arrest-syndrome patients.".
Meyer ASP, Johansson PI, Kjaergaard J, Frydland M, Meyer MAS, Henriksen HH, Thomsen JH, Wiberg SC, Hassager C, Ostrowski SR. Meyer ASP, et al. Am Heart J. 2020 Jan;219:9-20. doi: 10.1016/j.ahj.2019.10.002. Epub 2019 Oct 21. Am Heart J. 2020. PMID: 31710844 Clinical Trial.
Immune function as predictor of infectious complications and clinical outcome in patients undergoing solid organ transplantation (the ImmuneMo:SOT study): a prospective non-interventional observational trial.
Drabe CH, Sørensen SS, Rasmussen A, Perch M, Gustafsson F, Rezahosseini O, Lundgren JD, Ostrowski SR, Nielsen SD. Drabe CH, et al. BMC Infect Dis. 2019 Jul 3;19(1):573. doi: 10.1186/s12879-019-4207-9. BMC Infect Dis. 2019. PMID: 31269923 Free PMC article.
Management of bleeding in major burn surgery.
Welling H, Ostrowski SR, Stensballe J, Vestergaard MR, Partoft S, White J, Johansson PI. Welling H, et al. Burns. 2019 Jun;45(4):755-762. doi: 10.1016/j.burns.2018.08.024. Epub 2018 Oct 3. Burns. 2019. PMID: 30292526 Review.
Data-driven Development of ROTEM and TEG Algorithms for the Management of Trauma Hemorrhage: A Prospective Observational Multicenter Study.
Baksaas-Aasen K, Van Dieren S, Balvers K, Juffermans NP, Næss PA, Rourke C, Eaglestone S, Ostrowski SR, Stensballe J, Stanworth S, Maegele M, Goslings JC, Johansson PI, Brohi K, Gaarder C; TACTIC/INTRN collaborators. Baksaas-Aasen K, et al. Ann Surg. 2019 Dec;270(6):1178-1185. doi: 10.1097/SLA.0000000000002825. Ann Surg. 2019. PMID: 29794847
Plasma Concentration of Biomarkers Reflecting Endothelial Cell- and Glycocalyx Damage are Increased in Patients With Suspected ST-Elevation Myocardial Infarction Complicated by Cardiogenic Shock.
Frydland M, Ostrowski SR, Møller JE, Hadziselimovic E, Holmvang L, Ravn HB, Jensen LO, Pettersson AS, Kjaergaard J, Lindholm MG, Johansson PI, Hassager C. Frydland M, et al. Shock. 2018 Nov;50(5):538-544. doi: 10.1097/SHK.0000000000001123. Shock. 2018. PMID: 29438221
iTACTIC - implementing Treatment Algorithms for the Correction of Trauma-Induced Coagulopathy: study protocol for a multicentre, randomised controlled trial.
Baksaas-Aasen K, Gall L, Eaglestone S, Rourke C, Juffermans NP, Goslings JC, Naess PA, van Dieren S, Ostrowski SR, Stensballe J, Maegele M, Stanworth SJ, Gaarder C, Brohi K, Johansson PI. Baksaas-Aasen K, et al. Trials. 2017 Oct 18;18(1):486. doi: 10.1186/s13063-017-2224-9. Trials. 2017. PMID: 29047413 Free PMC article. Clinical Trial.
Syndecan-1: A Quantitative Marker for the Endotheliopathy of Trauma.
Gonzalez Rodriguez E, Ostrowski SR, Cardenas JC, Baer LA, Tomasek JS, Henriksen HH, Stensballe J, Cotton BA, Holcomb JB, Johansson PI, Wade CE. Gonzalez Rodriguez E, et al. J Am Coll Surg. 2017 Sep;225(3):419-427. doi: 10.1016/j.jamcollsurg.2017.05.012. Epub 2017 Jun 1. J Am Coll Surg. 2017. PMID: 28579548 Free article.
Combined effect of therapeutic strategies for bleeding injury on early survival, transfusion needs and correction of coagulopathy.
Balvers K, van Dieren S, Baksaas-Aasen K, Gaarder C, Brohi K, Eaglestone S, Stanworth S, Johansson PI, Ostrowski SR, Stensballe J, Maegele M, Goslings JC, Juffermans NP; Targeted Action for Curing Trauma-Induced Coagulopathy (TACTIC) Collaborators. Balvers K, et al. Br J Surg. 2017 Feb;104(3):222-229. doi: 10.1002/bjs.10330. Epub 2017 Jan 12. Br J Surg. 2017. PMID: 28079258
The effect of intraoperative and 6-h postoperative intravenous administration of low-dose prostacyclin on the endothelium, hemostasis, and hemodynamics in patients undergoing a pancreaticoduodenoctemy: a randomized-controlled pilot study.
Johansson PI, Mortensen CR, Nielsen T, Tollund C, Stensballe J, Hansen CP, Frederiksen HJ, Ostrowski SR. Johansson PI, et al. Eur J Gastroenterol Hepatol. 2017 Apr;29(4):400-406. doi: 10.1097/MEG.0000000000000800. Eur J Gastroenterol Hepatol. 2017. PMID: 27926661 Clinical Trial.
Prediction of non-recovery from ventilator-demanding acute respiratory failure, ARDS and death using lung damage biomarkers: data from a 1200-patient critical care randomized trial.
Jensen JS, Itenov TS, Thormar KM, Hein L, Mohr TT, Andersen MH, Løken J, Tousi H, Lundgren B, Boesen HC, Johansen ME, Ostrowski SR, Johansson PI, Grarup J, Vestbo J, Lundgren JD; Procalcitonin And Survival Study (PASS) Group. Jensen JS, et al. Ann Intensive Care. 2016 Dec;6(1):114. doi: 10.1186/s13613-016-0212-y. Epub 2016 Nov 21. Ann Intensive Care. 2016. PMID: 27873291 Free PMC article.
Haemostatic resuscitation in trauma: the next generation.
Stensballe J, Ostrowski SR, Johansson PI. Stensballe J, et al. Curr Opin Crit Care. 2016 Dec;22(6):591-597. doi: 10.1097/MCC.0000000000000359. Curr Opin Crit Care. 2016. PMID: 27811561 Review.
Sympathoadrenal activation and endotheliopathy are drivers of hypocoagulability and hyperfibrinolysis in trauma: A prospective observational study of 404 severely injured patients.
Ostrowski SR, Henriksen HH, Stensballe J, Gybel-Brask M, Cardenas JC, Baer LA, Cotton BA, Holcomb JB, Wade CE, Johansson PI. Ostrowski SR, et al. J Trauma Acute Care Surg. 2017 Feb;82(2):293-301. doi: 10.1097/TA.0000000000001304. J Trauma Acute Care Surg. 2017. PMID: 27779595
Marker of Endothelial Dysfunction Asymmetric Dimethylarginine Is Elevated in HIV Infection but Not Associated With Subclinical Atherosclerosis.
Haissman JM, Haugaard AK, Knudsen A, Kristoffersen US, Seljeflot I, Pedersen KK, Lebech AM, Hasbak P, Kjær A, Ostrowski SR, Gerstoft J, Trøseid M, Nielsen SD. Haissman JM, et al. J Acquir Immune Defic Syndr. 2016 Dec 15;73(5):507-513. doi: 10.1097/QAI.0000000000001148. J Acquir Immune Defic Syndr. 2016. PMID: 27509250
Endothelial Dysfunction in Resuscitated Cardiac Arrest (ENDO-RCA): safety and efficacy of low-dose prostacyclin administration and blood pressure target in addition to standard therapy, as compared to standard therapy alone, in post-cardiac arrest syndrome patients: study protocol for a randomized controlled trial.
Meyer AS, Ostrowski SR, Kjaergaard J, Johansson PI, Hassager C. Meyer AS, et al. Trials. 2016 Aug 2;17:378. doi: 10.1186/s13063-016-1477-z. Trials. 2016. PMID: 27484224 Free PMC article. Clinical Trial.
Identified metabolic signature for assessing red blood cell unit quality is associated with endothelial damage markers and clinical outcomes.
Bordbar A, Johansson PI, Paglia G, Harrison SJ, Wichuk K, Magnusdottir M, Valgeirsdottir S, Gybel-Brask M, Ostrowski SR, Palsson S, Rolfsson O, Sigurjónsson OE, Hansen MB, Gudmundsson S, Palsson BO. Bordbar A, et al. Transfusion. 2016 Apr;56(4):852-62. doi: 10.1111/trf.13460. Epub 2016 Jan 8. Transfusion. 2016. PMID: 26749434
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