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111 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Efficacy and safety of oxymetazoline for the treatment of rosacea: A meta-analysis.
Liu F, Zhou Q, Wang H, Fu H, Li Y, Tao M, Luo H, Cao Y. Liu F, et al. J Cosmet Dermatol. 2023 Sep;22(9):2408-2419. doi: 10.1111/jocd.15747. Epub 2023 May 2. J Cosmet Dermatol. 2023. PMID: 37128814 Review.
BACKGROUND: Since there is currently no conclusion on the efficacy and adverse effects of oxymetazoline, this meta-analysis attempts to explore its efficacy and adverse events, so as to provide guidance for clinical medication. ...CONCLUSION: Oxymetazoline is effect …
BACKGROUND: Since there is currently no conclusion on the efficacy and adverse effects of oxymetazoline, this meta-analysis attempts …
Topical Oxymetazoline for Fecal Incontinence in Patients with Spinal Cord Injury: A Double-Blind Randomized Controlled Crossover Study.
Barak N, Gecse KB, Takács I. Barak N, et al. Dis Colon Rectum. 2019 Feb;62(2):234-240. doi: 10.1097/DCR.0000000000001265. Dis Colon Rectum. 2019. PMID: 30451757 Clinical Trial.
OBJECTIVES: The aim of this study was to investigate the effect of the alpha-agonist oxymetazoline 1.0% on fecal incontinence in patients with spinal cord injury. DESIGN: This was a double-blind, crossover study. ...Results of the pharmacokinetic analysis indicate that the …
OBJECTIVES: The aim of this study was to investigate the effect of the alpha-agonist oxymetazoline 1.0% on fecal incontinence in pati …
The effects of topical oxymetazoline on eyelid position, eye redness, and patient-reported eye appearance: A randomized controlled trial.
Shoji MK, Markatia Z, Ameli K, Bayaraa M, Clauss KD, Ugradar S, Lee WW. Shoji MK, et al. J Plast Reconstr Aesthet Surg. 2023 May;80:66-74. doi: 10.1016/j.bjps.2023.02.006. Epub 2023 Feb 9. J Plast Reconstr Aesthet Surg. 2023. PMID: 36996503 Free article. Clinical Trial.
PURPOSE: This study assesses the effects of topical oxymetazoline 0.1% on eyelid position, eye redness, and patient-perceived eye appearance in patients without severe ptosis. ...Patients aged 18-100 years were randomized to receive one drop of oxymetazoline hydroch …
PURPOSE: This study assesses the effects of topical oxymetazoline 0.1% on eyelid position, eye redness, and patient-perceived eye app …
Does oxymetazoline increase the efficacy of nasal steroids in treating nasal polyposis?
Kirtsreesakul V, Khanuengkitkong T, Ruttanaphol S. Kirtsreesakul V, et al. Am J Rhinol Allergy. 2016 May;30(3):195-200. doi: 10.2500/ajra.2016.30.4294. Am J Rhinol Allergy. 2016. PMID: 27216350 Clinical Trial.
This study aimed to evaluate whether oxymetazoline administration produces any additive effect on nasal steroid therapy and whether rebound congestion develops after oxymetazoline treatment. ...There was no evidence of rebound congestion after 4 weeks of oxymetaz …
This study aimed to evaluate whether oxymetazoline administration produces any additive effect on nasal steroid therapy and whether r …
Oxymetazoline Applied Topically to the Nasal Mucosa Decreases Trans-Mucosal Nitrous Oxide Exchange for the Middle Ear.
Teixeira MS, Alper CM, Martin BS, Helal N, Doyle BM, Doyle WJ. Teixeira MS, et al. Ann Otol Rhinol Laryngol. 2016 May;125(5):400-7. doi: 10.1177/0003489415617776. Epub 2015 Nov 26. Ann Otol Rhinol Laryngol. 2016. PMID: 26611245 Free PMC article. Clinical Trial.

RESULTS: The analysis documented a significant effect of period on O2 saturation (N2O > room air, P = .03) and of treatment on blood pressure (oxymetazoline > placebo, P < .02) and the ME pressure-time slope (placebo > oxymetazoline, P = .05). CONCLUSION

…
RESULTS: The analysis documented a significant effect of period on O2 saturation (N2O > room air, P = .03) and of treatment on blood pres …
Topical Oxymetazoline Cream 1.0% for Persistent Facial Erythema Associated With Rosacea: Pooled Analysis of the Two Phase 3, 29-Day, Randomized, Controlled REVEAL Trials.
Stein-Gold L, Kircik L, Draelos ZD, Werschler P, DuBois J, Lain E, Baumann L, Goldberg D, Kaufman J, Tanghetti E, Ahluwalia G, Alvandi N, Weng E, Berk D. Stein-Gold L, et al. J Drugs Dermatol. 2018 Nov 1;17(11):1201-1208. J Drugs Dermatol. 2018. PMID: 30500142 Clinical Trial.
The primary outcome was achieved by significantly more patients in the oxymetazoline than vehicle group (P<0.001). Individual CEA and SSA scores and reduction in facial erythema (digital image analysis) favored oxymetazoline over vehicle (P<0.001). The inciden …
The primary outcome was achieved by significantly more patients in the oxymetazoline than vehicle group (P<0.001). Individual CEA …
Oxymetazoline in the treatment of allergic and non-infectious conjunctivitis.
Fox SL, Samson CR, Danzig MR. Fox SL, et al. J Int Med Res. 1979;7(6):528-30. doi: 10.1177/030006057900700609. J Int Med Res. 1979. PMID: 391626 Clinical Trial.
In a double-blind study of 141 patients, 0.025% oxymetazoline ophthalmic solution was compared with its vehicle in the treatment of allergic and non-infectious conjunctivitis. ...By the tenth day (second evaluation) the total improvement in hyperaemia was 95% for oxymet …
In a double-blind study of 141 patients, 0.025% oxymetazoline ophthalmic solution was compared with its vehicle in the treatment of a …
Oxymetazoline adds to the effectiveness of fluticasone furoate in the treatment of perennial allergic rhinitis.
Baroody FM, Brown D, Gavanescu L, DeTineo M, Naclerio RM. Baroody FM, et al. J Allergy Clin Immunol. 2011 Apr;127(4):927-34. doi: 10.1016/j.jaci.2011.01.037. Epub 2011 Mar 5. J Allergy Clin Immunol. 2011. PMID: 21377716 Clinical Trial.
OBJECTIVE: To determine whether the combination of fluticasone furoate and oxymetazoline is more efficacious than either agent alone, and to determine whether rhinitis medicamentosa develops after treatment. ...There was no evidence of rhinitis medicamentosa. CONCLUSION: T …
OBJECTIVE: To determine whether the combination of fluticasone furoate and oxymetazoline is more efficacious than either agent alone, …
A Randomized Controlled Pilot Study: Combined 595-nm Pulsed Dye Laser Treatment and Oxymetazoline Hydrochloride Topical Cream Superior to Oxymetazoline Hydrochloride Cream for Erythematotelangiectatic Rosacea.
Sodha P, Suggs A, Munavalli GS, Friedman PM. Sodha P, et al. Lasers Surg Med. 2021 Dec;53(10):1307-1315. doi: 10.1002/lsm.23439. Epub 2021 Jul 7. Lasers Surg Med. 2021. PMID: 34233378 Free PMC article. Clinical Trial.
BACKGROUND AND OBJECTIVES: We evaluated if oxymetazoline therapy combined with 595-nm pulsed dye laser (PDL) will be more beneficial than topical oxymetazoline alone for the improvement of erythematotelangiectatic rosacea. STUDY DESIGN/MATERIALS AND METHODS: This wa …
BACKGROUND AND OBJECTIVES: We evaluated if oxymetazoline therapy combined with 595-nm pulsed dye laser (PDL) will be more beneficial …
Oxymetazoline nasal spray three times daily for four weeks in normal subjects is not associated with rebound congestion or tachyphylaxis.
Watanabe H, Foo TH, Djazaeri B, Duncombe P, Mackay IS, Durham SR. Watanabe H, et al. Rhinology. 2003 Sep;41(3):167-74. Rhinology. 2003. PMID: 14579657 Clinical Trial.
Nasal patency was assessed at baseline and 15 minutes after oxymetazoline challenge at each clinic visit. Results demonstrated no significant increases in subjective nasal blockage throughout the 6 weeks study period in either oxymetazoline- or placebo-treated subje …
Nasal patency was assessed at baseline and 15 minutes after oxymetazoline challenge at each clinic visit. Results demonstrated no sig …
111 results

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