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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 2
2000 2
2001 1
2002 7
2003 5
2004 9
2005 9
2006 9
2007 11
2008 15
2009 15
2010 14
2011 18
2012 15
2013 7
2014 20
2015 10
2016 12
2017 16
2018 8
2019 7
2020 6
2021 1
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198 results
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Porphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer's disease.
Olsen I, Taubman MA, Singhrao SK. Olsen I, et al. J Oral Microbiol. 2016 Nov 22;8:33029. doi: 10.3402/jom.v8.33029. eCollection 2016. J Oral Microbiol. 2016. PMID: 27882863 Free PMC article. Review.
Porphyromonas gingivalis, a keystone pathogen in chronic periodontitis, has been found to associate with remote body organ inflammatory pathologies, including atherosclerosis and Alzheimer's disease (AD). ...In atherosclerosis, P. gingivalis red …
Porphyromonas gingivalis, a keystone pathogen in chronic periodontitis, has been found to associate with remote body organ inflammato …
Porphyromonas gingivalis Infection Accelerates Atherosclerosis Mediated by Oxidative Stress and Inflammatory Responses in ApoE-/- Mice.
Xuan Y, Shi Q, Liu GJ, Luan QX, Cai Y. Xuan Y, et al. Clin Lab. 2017 Oct 1;63(10):1627-1637. doi: 10.7754/Clin.Lab.2017.170410. Clin Lab. 2017. PMID: 29035447
BACKGROUND: The periodontal pathogen Porphyromonas gingivalis (P. gingivalis) has been proven to accelerate the development of atherosclerosis in apolipoprotein E (ApoE)-deficient mice. In this study, we used an ApoE knockout (ApoE-/-) mouse model with …
BACKGROUND: The periodontal pathogen Porphyromonas gingivalis (P. gingivalis) has been proven to accelerate the develop …
P. gingivalis in Periodontal Disease and Atherosclerosis - Scenes of Action for Antimicrobial Peptides and Complement.
Hussain M, Stover CM, Dupont A. Hussain M, et al. Front Immunol. 2015 Feb 10;6:45. doi: 10.3389/fimmu.2015.00045. eCollection 2015. Front Immunol. 2015. PMID: 25713575 Free PMC article. Review.
Because periodontal disease is associated with the development of atherosclerosis, it is important to understand the local immune response to P. gingivalis. Innate immune players, in particular, complement and antimicrobial peptides and their effects with reg …
Because periodontal disease is associated with the development of atherosclerosis, it is important to understand the local immune res …
Porphyromonas gingivalis accelerates atherosclerosis through oxidation of high-density lipoprotein.
Kim HJ, Cha GS, Kim HJ, Kwon EY, Lee JY, Choi J, Joo JY. Kim HJ, et al. J Periodontal Implant Sci. 2018 Feb 27;48(1):60-68. doi: 10.5051/jpis.2018.48.1.60. eCollection 2018 Feb. J Periodontal Implant Sci. 2018. PMID: 29535891 Free PMC article.
METHODS: P. gingivalis and THP-1 monocytes were cultured, and the extent of HDL oxidation induced by P. gingivalis was evaluated by a thiobarbituric acid-reactive substances (TBARS) assay. ...After incubating macrophages with HDL and P. gingi
METHODS: P. gingivalis and THP-1 monocytes were cultured, and the extent of HDL oxidation induced by P. gingivalis
Anti-P. gingivalis response correlates with atherosclerosis.
Ford PJ, Gemmell E, Timms P, Chan A, Preston FM, Seymour GJ. Ford PJ, et al. J Dent Res. 2007 Jan;86(1):35-40. doi: 10.1177/154405910708600105. J Dent Res. 2007. PMID: 17189460
Atherogenesis was examined in apolipoprotein-E-deficient (-/-) mice following intraperitoneal immunizations with P. gingivalis, C. pneumoniae, P. gingivalis, and C. pneumoniae or vehicle. Lesion area in the proximal aorta and levels of serum antibodies …
Atherogenesis was examined in apolipoprotein-E-deficient (-/-) mice following intraperitoneal immunizations with P. gingivalis
BMAL1-Downregulation Aggravates Porphyromonas Gingivalis-Induced Atherosclerosis by Encouraging Oxidative Stress.
Xie M, Tang Q, Nie J, Zhang C, Zhou X, Yu S, Sun J, Cheng X, Dong N, Hu Y, Chen L. Xie M, et al. Circ Res. 2020 Mar 13;126(6):e15-e29. doi: 10.1161/CIRCRESAHA.119.315502. Epub 2020 Feb 11. Circ Res. 2020. PMID: 32078488
OBJECTIVE: To elucidate the mechanisms of P gingivalis-accelerated atherosclerosis and explore novel therapeutic strategies of atherosclerotic cardiovascular diseases. ...Circadian clock disruption boosts P gingivalis-induced atherosclerosis
OBJECTIVE: To elucidate the mechanisms of P gingivalis-accelerated atherosclerosis and explore novel therapeutic strate …
The Porphyromonas gingivalis/Host Interactome Shows Enrichment in GWASdb Genes Related to Alzheimer's Disease, Diabetes and Cardiovascular Diseases.
Carter CJ, France J, Crean S, Singhrao SK. Carter CJ, et al. Front Aging Neurosci. 2017 Dec 12;9:408. doi: 10.3389/fnagi.2017.00408. eCollection 2017. Front Aging Neurosci. 2017. PMID: 29311898 Free PMC article.

This study analyzed the relationship between the P. gingivalis/host interactome and the genes identified in genome-wide association studies (GWAS) for the aforementioned conditions using data from GWASdb (P < 1E-03) and, in some cases, from the NCBI/EBI GW

This study analyzed the relationship between the P. gingivalis/host interactome and the genes identified in genome-wide associ …
Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids.
Kariu T, Nakao R, Ikeda T, Nakashima K, Potempa J, Imamura T. Kariu T, et al. J Periodontal Res. 2017 Feb;52(1):89-96. doi: 10.1111/jre.12372. Epub 2016 Mar 9. J Periodontal Res. 2017. PMID: 26957413 Free PMC article.
BACKGROUND AND OBJECTIVE: Porphyromonas gingivalis is considered a major pathogen of chronic periodontitis, which also may be implicated with systemic diseases such as atherosclerosis. Secreted cysteine proteases, gingipains Rgp and Kgp, are essential for P. …
BACKGROUND AND OBJECTIVE: Porphyromonas gingivalis is considered a major pathogen of chronic periodontitis, which also may be implica …
Role for Porphyromonas gingivalis in the progression of atherosclerosis.
Wang Q, Zhou X, Huang D. Wang Q, et al. Med Hypotheses. 2009 Jan;72(1):71-3. doi: 10.1016/j.mehy.2008.04.030. Epub 2008 Sep 30. Med Hypotheses. 2009. PMID: 18829178
An association between atherosclerosis and Porphyromonas gingivalis (P. gingivalis), a major periodontopathogen, has been shown. ...Results from these studies reinforce the connection between P. gingivalis and atherosclerosis. Give …
An association between atherosclerosis and Porphyromonas gingivalis (P. gingivalis), a major periodontopathogen, …
Porphyromonas gingivalis Induces Apoptosis and Autophagy via ER Stress in Human Umbilical Vein Endothelial Cells.
Hirasawa M, Kurita-Ochiai T. Hirasawa M, et al. Mediators Inflamm. 2018 Jul 29;2018:1967506. doi: 10.1155/2018/1967506. eCollection 2018. Mediators Inflamm. 2018. PMID: 30150893 Free PMC article.
It has been reported that periodontitis is associated with an increased risk of atherosclerosis. Accumulating evidence suggests that endothelial dysfunction is an early marker for atherosclerosis. ...The suppression of P. gingivalis-induced autophagy b …
It has been reported that periodontitis is associated with an increased risk of atherosclerosis. Accumulating evidence suggests that …
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