paiardini a - Search Results

Year	Number of Results
2001	1
2003	3
2004	2
2005	1
2006	2
2007	2
2008	3
2009	5
2010	2
2011	4
2012	6
2013	11
2014	6
2015	9
2016	7
2017	12
2018	10
2019	6
2020	10
2021	8
2022	9
2023	2

1

Revisiting degron motifs in human AURKA required for its targeting by APC/C^FZR1.

Abdelbaki A, Ascanelli C, Okoye CN, Akman HB, Janson G, Min M, Marcozzi C, Hagting A, Grant R, De Luca M, Asteriti IA, Guarguaglini G, Paiardini A, Lindon C. Abdelbaki A, et al. Among authors: paiardini a. Life Sci Alliance. 2022 Nov 30;6(2):e202201372. doi: 10.26508/lsa.202201372. Print 2023 Feb. Life Sci Alliance. 2022. PMID: 36450448 Free PMC article.

2

A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression.

Di Nisio E, Licursi V, Mannironi C, Buglioni V, Paiardini A, Robusti G, Noberini R, Bonaldi T, Negri R. Di Nisio E, et al. Among authors: paiardini a. Cancer Gene Ther. 2023 Jan 26. doi: 10.1038/s41417-022-00584-w. Online ahead of print. Cancer Gene Ther. 2023. PMID: 36697763

3

Boosting the Full Potential of PyMOL with Structural Biology Plugins.

Rosignoli S, Paiardini A. Rosignoli S, et al. Among authors: paiardini a. Biomolecules. 2022 Nov 27;12(12):1764. doi: 10.3390/biom12121764. Biomolecules. 2022. PMID: 36551192 Free PMC article. Review.

4

DockingPie: a consensus docking plugin for PyMOL.

Rosignoli S, Paiardini A. Rosignoli S, et al. Among authors: paiardini a. Bioinformatics. 2022 Sep 2;38(17):4233-4234. doi: 10.1093/bioinformatics/btac452. Bioinformatics. 2022. PMID: 35792827

5

SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity.

Amormino C, Tedeschi V, Paldino G, Arcieri S, Fiorillo MT, Paiardini A, Tuosto L, Kunkl M. Amormino C, et al. Among authors: paiardini a. Cells. 2022 Aug 15;11(16):2526. doi: 10.3390/cells11162526. Cells. 2022. PMID: 36010602 Free PMC article.

6

A Novel Hypothesis on Choroideremia-Manifesting Female Carriers: Could CHM In-Frame Variants Exert a Dominant Negative Effect? A Case Report.

Di Giosaffatte N, Valiante M, Tricarico S, Parise G, De Negri AM, Ricciotti G, Florean L, Paiardini A, Bottillo I, Grammatico P. Di Giosaffatte N, et al. Among authors: paiardini a. Genes (Basel). 2022 Jul 17;13(7):1268. doi: 10.3390/genes13071268. Genes (Basel). 2022. PMID: 35886051 Free PMC article.

7

A Short ERAP2 That Binds IRAP Is Expressed in Macrophages Independently of Gene Variation.

Mattorre B, Caristi S, Donato S, Volpe E, Faiella M, Paiardini A, Sorrentino R, Paladini F. Mattorre B, et al. Among authors: paiardini a. Int J Mol Sci. 2022 Apr 29;23(9):4961. doi: 10.3390/ijms23094961. Int J Mol Sci. 2022. PMID: 35563348 Free PMC article.

8

Nutrient Sensing and Biofilm Modulation: The Example of L-arginine in Pseudomonas.

Scribani Rossi C, Barrientos-Moreno L, Paone A, Cutruzzolà F, Paiardini A, Espinosa-Urgel M, Rinaldo S. Scribani Rossi C, et al. Among authors: paiardini a. Int J Mol Sci. 2022 Apr 15;23(8):4386. doi: 10.3390/ijms23084386. Int J Mol Sci. 2022. PMID: 35457206 Free PMC article. Review.

9

Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex.

Spizzichino S, Boi D, Boumis G, Lucchi R, Liberati FR, Capelli D, Montanari R, Pochetti G, Piacentini R, Parisi G, Paone A, Rinaldo S, Contestabile R, Tramonti A, Paiardini A, Giardina G, Cutruzzolà F. Spizzichino S, et al. Among authors: paiardini a. FEBS J. 2022 Mar;289(6):1625-1649. doi: 10.1111/febs.16248. Epub 2021 Nov 12. FEBS J. 2022. PMID: 34694685 Free PMC article.

10

Prediction and Modeling of Protein-Protein Interactions Using "Spotted" Peptides with a Template-Based Approach.

Gasbarri C, Rosignoli S, Janson G, Boi D, Paiardini A. Gasbarri C, et al. Among authors: paiardini a. Biomolecules. 2022 Jan 25;12(2):201. doi: 10.3390/biom12020201. Biomolecules. 2022. PMID: 35204702 Free PMC article.

11

PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc.

Boi D, Souvalidou F, Capelli D, Polverino F, Marini G, Montanari R, Pochetti G, Tramonti A, Contestabile R, Trisciuoglio D, Carpinelli P, Ascanelli C, Lindon C, De Leo A, Saviano M, Di Santo R, Costi R, Guarguaglini G, Paiardini A. Boi D, et al. Among authors: paiardini a. Int J Mol Sci. 2021 Dec 4;22(23):13122. doi: 10.3390/ijms222313122. Int J Mol Sci. 2021. PMID: 34884931 Free PMC article.

12

PyMod 3: a complete suite for structural bioinformatics in PyMOL.

Janson G, Paiardini A. Janson G, et al. Among authors: paiardini a. Bioinformatics. 2021 Jun 16;37(10):1471-1472. doi: 10.1093/bioinformatics/btaa849. Bioinformatics. 2021. PMID: 33010156

13

Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer.

Naso FD, Boi D, Ascanelli C, Pamfil G, Lindon C, Paiardini A, Guarguaglini G. Naso FD, et al. Among authors: paiardini a. Oncogene. 2021 Jun;40(23):3917-3928. doi: 10.1038/s41388-021-01766-w. Epub 2021 May 13. Oncogene. 2021. PMID: 33981003 Free PMC article. Review.

14

Bacterial Oxidases of the Cytochrome bd Family: Redox Enzymes of Unique Structure, Function, and Utility As Drug Targets.

Borisov VB, Siletsky SA, Paiardini A, Hoogewijs D, Forte E, Giuffrè A, Poole RK. Borisov VB, et al. Among authors: paiardini a. Antioxid Redox Signal. 2021 Jun 1;34(16):1280-1318. doi: 10.1089/ars.2020.8039. Epub 2020 Nov 9. Antioxid Redox Signal. 2021. PMID: 32924537 Free PMC article. Review.

15

Phosphorylation, Mg-ADP, and Inhibitors Differentially Shape the Conformational Dynamics of the A-Loop of Aurora-A.

Musavizadeh Z, Grottesi A, Guarguaglini G, Paiardini A. Musavizadeh Z, et al. Among authors: paiardini a. Biomolecules. 2021 Apr 12;11(4):567. doi: 10.3390/biom11040567. Biomolecules. 2021. PMID: 33921540 Free PMC article.

16

The Archaeal Elongation Factor EF-2 Induces the Release of aIF6 From 50S Ribosomal Subunit.

Lo Gullo G, De Santis ML, Paiardini A, Rosignoli S, Romagnoli A, La Teana A, Londei P, Benelli D. Lo Gullo G, et al. Among authors: paiardini a. Front Microbiol. 2021 Mar 24;12:631297. doi: 10.3389/fmicb.2021.631297. eCollection 2021. Front Microbiol. 2021. PMID: 33841359 Free PMC article.

17

Studying GGDEF Domain in the Act: Minimize Conformational Frustration to Prevent Artefacts.

Mantoni F, Scribani Rossi C, Paiardini A, Di Matteo A, Cappellacci L, Petrelli R, Ricciutelli M, Paone A, Cutruzzolà F, Giardina G, Rinaldo S. Mantoni F, et al. Among authors: paiardini a. Life (Basel). 2021 Jan 6;11(1):31. doi: 10.3390/life11010031. Life (Basel). 2021. PMID: 33418960 Free PMC article.

18

Intronic Determinants Coordinate Charme lncRNA Nuclear Activity through the Interaction with MATR3 and PTBP1.

Desideri F, Cipriano A, Petrezselyova S, Buonaiuto G, Santini T, Kasparek P, Prochazka J, Janson G, Paiardini A, Calicchio A, Colantoni A, Sedlacek R, Bozzoni I, Ballarino M. Desideri F, et al. Among authors: paiardini a. Cell Rep. 2020 Dec 22;33(12):108548. doi: 10.1016/j.celrep.2020.108548. Cell Rep. 2020. PMID: 33357424 Free PMC article.

19

A Single Center Retrospective Review of Patients from Central Italy Tested for Melanoma Predisposition Genes.

De Simone P, Bottillo I, Valiante M, Iorio A, De Bernardo C, Majore S, D'Angelantonio D, Valentini T, Sperduti I, Piemonte P, Eibenschutz L, Ferrari A, Carbone A, Buccini P, Paiardini A, Silipo V, Frascione P, Grammatico P. De Simone P, et al. Among authors: paiardini a. Int J Mol Sci. 2020 Dec 11;21(24):9432. doi: 10.3390/ijms21249432. Int J Mol Sci. 2020. PMID: 33322357 Free PMC article.

20

Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity.

Bouzidi A, Magnifico MC, Paiardini A, Macone A, Boumis G, Giardina G, Rinaldo S, Liberati FR, Lauro C, Limatola C, Lanzillotta C, Tramutola A, Perluigi M, Sgarbi G, Solaini G, Baracca A, Paone A, Cutruzzolà F. Bouzidi A, et al. Among authors: paiardini a. Cell Death Dis. 2020 Nov 26;11(11):1012. doi: 10.1038/s41419-020-03215-0. Cell Death Dis. 2020. PMID: 33243973 Free PMC article.

21

A novel CDKN2A in-frame deletion associated with pancreatic cancer-melanoma syndrome.

Bottillo I, Valiante M, Menale L, Paiardini A, Papi L, Janson G, Sestini R, Iorio A, De Simone P, Frascione P, Grammatico P. Bottillo I, et al. Among authors: paiardini a. Dermatol Online J. 2020 Aug 15;26(8):13030/qt5t22m5gk. Dermatol Online J. 2020. PMID: 32941720 Free article.

22

SMaRT lncRNA controls translation of a G-quadruplex-containing mRNA antagonizing the DHX36 helicase.

Martone J, Mariani D, Santini T, Setti A, Shamloo S, Colantoni A, Capparelli F, Paiardini A, Dimartino D, Morlando M, Bozzoni I. Martone J, et al. Among authors: paiardini a. EMBO Rep. 2020 Jun 4;21(6):e49942. doi: 10.15252/embr.201949942. Epub 2020 Apr 26. EMBO Rep. 2020. PMID: 32337838 Free PMC article.

23

Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1.

Botta L, Filippi S, Zippilli C, Cesarini S, Bizzarri BM, Cirigliano A, Rinaldi T, Paiardini A, Fiorucci D, Saladino R, Negri R, Benedetti P. Botta L, et al. Among authors: paiardini a. ACS Med Chem Lett. 2020 Apr 10;11(5):1035-1040. doi: 10.1021/acsmedchemlett.0c00131. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435422 Free PMC article.

24

From PARP1 to TNKS2 Inhibition: A Structure-Based Approach.

Tomassi S, Pfahler J, Mautone N, Rovere A, Esposito C, Passeri D, Pellicciari R, Novellino E, Pannek M, Steegborn C, Paiardini A, Mai A, Rotili D. Tomassi S, et al. Among authors: paiardini a. ACS Med Chem Lett. 2020 Feb 3;11(5):862-868. doi: 10.1021/acsmedchemlett.9b00654. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435397 Free PMC article.

25

Insights into PPARγ Phosphorylation and Its Inhibition Mechanism.

Montanari R, Capelli D, Yamamoto K, Awaishima H, Nishikata K, Barendregt A, Heck AJR, Loiodice F, Altieri F, Paiardini A, Grottesi A, Pirone L, Pedone E, Peiretti F, Brunel JM, Itoh T, Pochetti G. Montanari R, et al. Among authors: paiardini a. J Med Chem. 2020 May 14;63(9):4811-4823. doi: 10.1021/acs.jmedchem.0c00048. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32239932 Free article.

26

Prenatal whole exome sequencing detects a new homozygous fukutin (FKTN) mutation in a fetus with an ultrasound suspicion of familial Dandy-Walker malformation.

Traversa A, Bernardo S, Paiardini A, Giovannetti A, Marchionni E, Genovesi ML, Guadagnolo D, Torres B, Paolacci S, Bernardini L, Mazza T, Carella M, Caputo V, Pizzuti A. Traversa A, et al. Among authors: paiardini a. Mol Genet Genomic Med. 2020 Jan;8(1):e1054. doi: 10.1002/mgg3.1054. Epub 2019 Nov 22. Mol Genet Genomic Med. 2020. PMID: 31756055 Free PMC article.

27

Revisiting the "satisfaction of spatial restraints" approach of MODELLER for protein homology modeling.

Janson G, Grottesi A, Pietrosanto M, Ausiello G, Guarguaglini G, Paiardini A. Janson G, et al. Among authors: paiardini a. PLoS Comput Biol. 2019 Dec 17;15(12):e1007219. doi: 10.1371/journal.pcbi.1007219. eCollection 2019 Dec. PLoS Comput Biol. 2019. PMID: 31846452 Free PMC article.

28

R180T variant of δ-ornithine aminotransferase associated with gyrate atrophy: biochemical, computational, X-ray and NMR studies provide insight into its catalytic features.

Montioli R, Paiardini A, Giardina G, Zanzoni S, Cutruzzola F, Cellini B, Borri Voltattorni C. Montioli R, et al. Among authors: paiardini a. FEBS J. 2019 Jul;286(14):2787-2798. doi: 10.1111/febs.14843. Epub 2019 Apr 15. FEBS J. 2019. PMID: 30957963 Free article.

29

A novel compound heterozygous genotype associated with aromatic amino acid decarboxylase deficiency: Clinical aspects and biochemical studies.

Montioli R, Battini R, Paiardini A, Tolve M, Bertoldi M, Carducci C, Leuzzi V, Borri Voltattorni C. Montioli R, et al. Among authors: paiardini a. Mol Genet Metab. 2019 Jun;127(2):132-137. doi: 10.1016/j.ymgme.2019.05.004. Epub 2019 May 10. Mol Genet Metab. 2019. PMID: 31104889

30

The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism.

Guiducci G, Paone A, Tramonti A, Giardina G, Rinaldo S, Bouzidi A, Magnifico MC, Marani M, Menendez JA, Fatica A, Macone A, Armaos A, Tartaglia GG, Contestabile R, Paiardini A, Cutruzzolà F. Guiducci G, et al. Among authors: paiardini a. Nucleic Acids Res. 2019 May 7;47(8):4240-4254. doi: 10.1093/nar/gkz129. Nucleic Acids Res. 2019. PMID: 30809670 Free PMC article.

31

N⁶-Methyladenosine (m⁶A): A Promising New Molecular Target in Acute Myeloid Leukemia.

Ianniello Z, Paiardini A, Fatica A. Ianniello Z, et al. Among authors: paiardini a. Front Oncol. 2019 Apr 9;9:251. doi: 10.3389/fonc.2019.00251. eCollection 2019. Front Oncol. 2019. PMID: 31024852 Free PMC article. Review.

32

Corrigendum to "Pyridoxine-5'-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g>A (P.·Arg116gln) mutation" [Mol. Genet. Metab. 122/1-2 (2017) 135-142].

di Salvo ML, Mastrangelo M, Nogués I, Tolve M, Paiardini A, Carducci C, Mei D, Montomoli M, Tramonti A, Guerrini R, Contestabile R, Leuzzi V. di Salvo ML, et al. Among authors: paiardini a. Mol Genet Metab. 2018 Dec;125(4):359. doi: 10.1016/j.ymgme.2018.02.017. Epub 2018 Mar 14. Mol Genet Metab. 2018. PMID: 29548777 No abstract available.

33

Cysteine 180 Is a Redox Sensor Modulating the Activity of Human Pyridoxal 5'-Phosphate Histidine Decarboxylase.

Rossignoli G, Grottesi A, Bisello G, Montioli R, Borri Voltattorni C, Paiardini A, Bertoldi M. Rossignoli G, et al. Among authors: paiardini a. Biochemistry. 2018 Nov 6;57(44):6336-6348. doi: 10.1021/acs.biochem.8b00625. Epub 2018 Oct 29. Biochemistry. 2018. PMID: 30346159

34

Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa.

Mantoni F, Paiardini A, Brunotti P, D'Angelo C, Cervoni L, Paone A, Cappellacci L, Petrelli R, Ricciutelli M, Leoni L, Rampioni G, Arcovito A, Rinaldo S, Cutruzzolà F, Giardina G. Mantoni F, et al. Among authors: paiardini a. FEBS J. 2018 Oct;285(20):3815-3834. doi: 10.1111/febs.14634. Epub 2018 Sep 7. FEBS J. 2018. PMID: 30106221 Free article.

35

A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa.

Paiardini A, Mantoni F, Giardina G, Paone A, Janson G, Leoni L, Rampioni G, Cutruzzolà F, Rinaldo S. Paiardini A, et al. Proteins. 2018 Oct;86(10):1088-1096. doi: 10.1002/prot.25587. Epub 2018 Sep 8. Proteins. 2018. PMID: 30040157

36

The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.

Giardina G, Paone A, Tramonti A, Lucchi R, Marani M, Magnifico MC, Bouzidi A, Pontecorvi V, Guiducci G, Zamparelli C, Rinaldo S, Paiardini A, Contestabile R, Cutruzzolà F. Giardina G, et al. Among authors: paiardini a. FEBS J. 2018 Sep;285(17):3238-3253. doi: 10.1111/febs.14610. Epub 2018 Aug 7. FEBS J. 2018. PMID: 30035852 Free article.

37

Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes.

Tramonti A, Paiardini A, Paone A, Bouzidi A, Giardina G, Guiducci G, Magnifico MC, Rinaldo S, McDermott L, Menendez JA, Contestabile R, Cutruzzolà F. Tramonti A, et al. Among authors: paiardini a. Arch Biochem Biophys. 2018 Sep 1;653:71-79. doi: 10.1016/j.abb.2018.07.001. Epub 2018 Jul 4. Arch Biochem Biophys. 2018. PMID: 29991441

38

Functional Characterization and Structure-Guided Mutational Analysis of the Transsulfuration Enzyme Cystathionine γ-Lyase from Toxoplasma gondii.

Maresi E, Janson G, Fruncillo S, Paiardini A, Vallone R, Dominici P, Astegno A. Maresi E, et al. Among authors: paiardini a. Int J Mol Sci. 2018 Jul 20;19(7):2111. doi: 10.3390/ijms19072111. Int J Mol Sci. 2018. PMID: 30036991 Free PMC article.

39

Familial hypomagnesaemia, Hypercalciuria and Nephrocalcinosis associated with a novel mutation of the highly conserved leucine residue 116 of Claudin 16 in a Chinese patient with a delayed diagnosis: a case report.

Lu J, Zhao X, Paiardini A, Lang Y, Bottillo I, Shao L. Lu J, et al. Among authors: paiardini a. BMC Nephrol. 2018 Jul 13;19(1):181. doi: 10.1186/s12882-018-0979-1. BMC Nephrol. 2018. PMID: 30005619 Free PMC article.

40

A novel germline mutation in CDK4 codon 24 associated to familial melanoma.

Bottillo I, La Starza R, Radio FC, Molica C, Pedace L, Pierini T, De Bernardo C, Stingeni L, Bargiacchi S, Paiardini A, Janson G, Mecucci C, Grammatico P. Bottillo I, et al. Among authors: paiardini a. Clin Genet. 2018 Apr;93(4):934-935. doi: 10.1111/cge.13129. Epub 2017 Nov 10. Clin Genet. 2018. PMID: 29124743 No abstract available.

41

Heterozygosis in aromatic amino acid decarboxylase deficiency: Evidence for a positive interallelic complementation between R347Q and R358H mutations.

Montioli R, Janson G, Paiardini A, Bertoldi M, Borri Voltattorni C. Montioli R, et al. Among authors: paiardini a. IUBMB Life. 2018 Mar;70(3):215-223. doi: 10.1002/iub.1718. Epub 2018 Jan 22. IUBMB Life. 2018. PMID: 29356298 Free article.

42

Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO).

di Salvo ML, Mastrangelo M, Nogués I, Tolve M, Paiardini A, Carducci C, Mei D, Montomoli M, Tramonti A, Guerrini R, Contestabile R, Leuzzi V. di Salvo ML, et al. Among authors: paiardini a. Data Brief. 2017 Oct 28;15:868-875. doi: 10.1016/j.dib.2017.10.032. eCollection 2017 Dec. Data Brief. 2017. PMID: 29379851 Free PMC article.

43

Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7γ.

Di Matteo A, Franceschini M, Paiardini A, Grottesi A, Chiarella S, Rocchio S, Di Natale C, Marasco D, Vitagliano L, Travaglini-Allocatelli C, Federici L. Di Matteo A, et al. Among authors: paiardini a. Oncogenesis. 2017 Sep 18;6(9):e379. doi: 10.1038/oncsis.2017.78. Oncogenesis. 2017. PMID: 28920929 Free PMC article.

44

Radiation damage at the active site of human alanine:glyoxylate aminotransferase reveals that the cofactor position is finely tuned during catalysis.

Giardina G, Paiardini A, Montioli R, Cellini B, Voltattorni CB, Cutruzzolà F. Giardina G, et al. Among authors: paiardini a. Sci Rep. 2017 Sep 15;7(1):11704. doi: 10.1038/s41598-017-11948-w. Sci Rep. 2017. PMID: 28916765 Free PMC article.

45

Pyridoxine-5'-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g>A (P.·Arg116gln) mutation.

di Salvo ML, Mastrangelo M, Nogués I, Tolve M, Paiardini A, Carducci C, Mei D, Montomoli M, Tramonti A, Guerrini R, Contestabile R, Leuzzi V. di Salvo ML, et al. Among authors: paiardini a. Mol Genet Metab. 2017 Sep;122(1-2):135-142. doi: 10.1016/j.ymgme.2017.08.003. Epub 2017 Aug 12. Mol Genet Metab. 2017. PMID: 28818555

46

Betulinic acid is a PPARγ antagonist that improves glucose uptake, promotes osteogenesis and inhibits adipogenesis.

Brusotti G, Montanari R, Capelli D, Cattaneo G, Laghezza A, Tortorella P, Loiodice F, Peiretti F, Bonardo B, Paiardini A, Calleri E, Pochetti G. Brusotti G, et al. Among authors: paiardini a. Sci Rep. 2017 Jul 18;7(1):5777. doi: 10.1038/s41598-017-05666-6. Sci Rep. 2017. PMID: 28720829 Free PMC article.

47

Identification of small molecule inhibitors of the Aurora-A/TPX2 complex.

Asteriti IA, Daidone F, Colotti G, Rinaldo S, Lavia P, Guarguaglini G, Paiardini A. Asteriti IA, et al. Among authors: paiardini a. Oncotarget. 2017 May 9;8(19):32117-32133. doi: 10.18632/oncotarget.16738. Oncotarget. 2017. PMID: 28389630 Free PMC article.

48

Unique substrate specificity of ornithine aminotransferase from Toxoplasma gondii.

Astegno A, Maresi E, Bertoldi M, La Verde V, Paiardini A, Dominici P. Astegno A, et al. Among authors: paiardini a. Biochem J. 2017 Mar 7;474(6):939-955. doi: 10.1042/BCJ20161021. Biochem J. 2017. PMID: 28126740

49

Glucose Metabolism in the Progression of Prostate Cancer.

Cutruzzolà F, Giardina G, Marani M, Macone A, Paiardini A, Rinaldo S, Paone A. Cutruzzolà F, et al. Among authors: paiardini a. Front Physiol. 2017 Feb 21;8:97. doi: 10.3389/fphys.2017.00097. eCollection 2017. Front Physiol. 2017. PMID: 28270771 Free PMC article. Review.

50

PyMod 2.0: improvements in protein sequence-structure analysis and homology modeling within PyMOL.

Janson G, Zhang C, Prado MG, Paiardini A. Janson G, et al. Among authors: paiardini a. Bioinformatics. 2017 Feb 1;33(3):444-446. doi: 10.1093/bioinformatics/btw638. Bioinformatics. 2017. PMID: 28158668

51

Discovering Selective Diguanylate Cyclase Inhibitors: From PleD to Discrimination of the Active Site of Cyclic-di-GMP Phosphodiesterases.

Rinaldo S, Giardina G, Mantoni F, Paiardini A, Paone A, Cutruzzolà F. Rinaldo S, et al. Among authors: paiardini a. Methods Mol Biol. 2017;1657:431-453. doi: 10.1007/978-1-4939-7240-1_32. Methods Mol Biol. 2017. PMID: 28889312

52

New Insights Emerging from Recent Investigations on Human Group II Pyridoxal 5'-Phosphate Decarboxylases.

Paiardini A, Giardina G, Rossignoli G, Voltattorni CB, Bertoldi M. Paiardini A, et al. Curr Med Chem. 2017;24(3):226-244. doi: 10.2174/0929867324666161123093339. Curr Med Chem. 2017. PMID: 27881066 Review.

53

Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming.

Paiardini A, Tramonti A, Schirch D, Guiducci G, di Salvo ML, Fiascarelli A, Giorgi A, Maras B, Cutruzzolà F, Contestabile R. Paiardini A, et al. Biochim Biophys Acta. 2016 Nov;1864(11):1506-17. doi: 10.1016/j.bbapap.2016.08.010. Epub 2016 Aug 13. Biochim Biophys Acta. 2016. PMID: 27530298

54

Prediction and visualization data for the interpretation of sarcomeric and non-sarcomeric DNA variants found in patients with hypertrophic cardiomyopathy.

Bottillo I, D'Angelantonio D, Caputo V, Paiardini A, Lipari M, De Bernardo C, Majore S, Castori M, Zachara E, Re F, Grammatico P. Bottillo I, et al. Among authors: paiardini a. Data Brief. 2016 Mar 10;7:607-13. doi: 10.1016/j.dib.2016.03.004. eCollection 2016 Jun. Data Brief. 2016. PMID: 27054166 Free PMC article.

55

The novel R347g pathogenic mutation of aromatic amino acid decarboxylase provides additional molecular insights into enzyme catalysis and deficiency.

Montioli R, Paiardini A, Kurian MA, Dindo M, Rossignoli G, Heales SJR, Pope S, Voltattorni CB, Bertoldi M. Montioli R, et al. Among authors: paiardini a. Biochim Biophys Acta. 2016 Jun;1864(6):676-682. doi: 10.1016/j.bbapap.2016.03.011. Epub 2016 Mar 17. Biochim Biophys Acta. 2016. PMID: 26994895

56

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions.

Drinkwater N, Vinh NB, Mistry SN, Bamert RS, Ruggeri C, Holleran JP, Loganathan S, Paiardini A, Charman SA, Powell AK, Avery VM, McGowan S, Scammells PJ. Drinkwater N, et al. Among authors: paiardini a. Eur J Med Chem. 2016 Mar 3;110:43-64. doi: 10.1016/j.ejmech.2016.01.015. Epub 2016 Jan 13. Eur J Med Chem. 2016. PMID: 26807544

57

Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy.

Bottillo I, D'Angelantonio D, Caputo V, Paiardini A, Lipari M, De Bernardo C, Giannarelli D, Pizzuti A, Majore S, Castori M, Zachara E, Re F, Grammatico P. Bottillo I, et al. Among authors: paiardini a. Gene. 2016 Feb 15;577(2):227-35. doi: 10.1016/j.gene.2015.11.048. Epub 2015 Dec 2. Gene. 2016. PMID: 26656175

58

A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.

Marani M, Paone A, Fiascarelli A, Macone A, Gargano M, Rinaldo S, Giardina G, Pontecorvi V, Koes D, McDermott L, Yang T, Paiardini A, Contestabile R, Cutruzzolà F. Marani M, et al. Among authors: paiardini a. Oncotarget. 2016 Jan 26;7(4):4570-83. doi: 10.18632/oncotarget.6726. Oncotarget. 2016. PMID: 26717037 Free PMC article.

59

In Silico Discovery and In Vitro Validation of Catechol-Containing Sulfonohydrazide Compounds as Potent Inhibitors of the Diguanylate Cyclase PleD.

Fernicola S, Paiardini A, Giardina G, Rampioni G, Leoni L, Cutruzzolà F, Rinaldo S. Fernicola S, et al. Among authors: paiardini a. J Bacteriol. 2015 Sep 28;198(1):147-56. doi: 10.1128/JB.00742-15. Print 2016 Jan 1. J Bacteriol. 2015. PMID: 26416830 Free PMC article.

60

Synthesis of Triazole-Linked Analogues of c-di-GMP and Their Interactions with Diguanylate Cyclase.

Fernicola S, Torquati I, Paiardini A, Giardina G, Rampioni G, Messina M, Leoni L, Del Bello F, Petrelli R, Rinaldo S, Cappellacci L, Cutruzzolà F. Fernicola S, et al. Among authors: paiardini a. J Med Chem. 2015 Oct 22;58(20):8269-84. doi: 10.1021/acs.jmedchem.5b01184. Epub 2015 Oct 12. J Med Chem. 2015. PMID: 26426545

61

Identification and Validation of a Potent Dual Inhibitor of the P. falciparum M1 and M17 Aminopeptidases Using Virtual Screening.

Ruggeri C, Drinkwater N, Sivaraman KK, Bamert RS, McGowan S, Paiardini A. Ruggeri C, et al. Among authors: paiardini a. PLoS One. 2015 Sep 25;10(9):e0138957. doi: 10.1371/journal.pone.0138957. eCollection 2015. PLoS One. 2015. PMID: 26406322 Free PMC article.

62

Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site.

Rinaldo S, Paiardini A, Stelitano V, Brunotti P, Cervoni L, Fernicola S, Protano C, Vitali M, Cutruzzolà F, Giardina G. Rinaldo S, et al. Among authors: paiardini a. J Bacteriol. 2015 Apr;197(8):1525-35. doi: 10.1128/JB.02606-14. Epub 2015 Feb 17. J Bacteriol. 2015. PMID: 25691523 Free PMC article.

63

X-ray crystal structures of an orally available aminopeptidase inhibitor, Tosedostat, bound to anti-malarial drug targets PfA-M1 and PfA-M17.

Drinkwater N, Bamert RS, Sivaraman KK, Paiardini A, McGowan S. Drinkwater N, et al. Among authors: paiardini a. Proteins. 2015 Apr;83(4):789-95. doi: 10.1002/prot.24771. Epub 2015 Feb 28. Proteins. 2015. PMID: 25645579

64

How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state.

Giardina G, Brunotti P, Fiascarelli A, Cicalini A, Costa MG, Buckle AM, di Salvo ML, Giorgi A, Marani M, Paone A, Rinaldo S, Paiardini A, Contestabile R, Cutruzzolà F. Giardina G, et al. Among authors: paiardini a. FEBS J. 2015 Apr;282(7):1225-41. doi: 10.1111/febs.13211. Epub 2015 Feb 13. FEBS J. 2015. PMID: 25619277 Free article.

65

Screening and in vitro testing of antifolate inhibitors of human cytosolic serine hydroxymethyltransferase.

Paiardini A, Fiascarelli A, Rinaldo S, Daidone F, Giardina G, Koes DR, Parroni A, Montini G, Marani M, Paone A, McDermott LA, Contestabile R, Cutruzzolà F. Paiardini A, et al. ChemMedChem. 2015 Mar;10(3):490-7. doi: 10.1002/cmdc.201500028. Epub 2015 Feb 10. ChemMedChem. 2015. PMID: 25677305 Free PMC article.

66

Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum aminopeptidases, M1, M17 and M18.

Paiardini A, Bamert RS, Kannan-Sivaraman K, Drinkwater N, Mistry SN, Scammells PJ, McGowan S. Paiardini A, et al. PLoS One. 2015 Feb 20;10(2):e0115859. doi: 10.1371/journal.pone.0115859. eCollection 2015. PLoS One. 2015. PMID: 25700165 Free PMC article.

67

SHMT1 knockdown induces apoptosis in lung cancer cells by causing uracil misincorporation.

Paone A, Marani M, Fiascarelli A, Rinaldo S, Giardina G, Contestabile R, Paiardini A, Cutruzzolà F. Paone A, et al. Among authors: paiardini a. Cell Death Dis. 2014 Nov 20;5(11):e1525. doi: 10.1038/cddis.2014.482. Cell Death Dis. 2014. PMID: 25412303 Free PMC article.

68

Two-pronged attack: dual inhibition of Plasmodium falciparum M1 and M17 metalloaminopeptidases by a novel series of hydroxamic acid-based inhibitors.

Mistry SN, Drinkwater N, Ruggeri C, Sivaraman KK, Loganathan S, Fletcher S, Drag M, Paiardini A, Avery VM, Scammells PJ, McGowan S. Mistry SN, et al. Among authors: paiardini a. J Med Chem. 2014 Nov 13;57(21):9168-83. doi: 10.1021/jm501323a. Epub 2014 Oct 24. J Med Chem. 2014. PMID: 25299353

69

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis.

Kass I, Hoke DE, Costa MG, Reboul CF, Porebski BT, Cowieson NP, Leh H, Pennacchietti E, McCoey J, Kleifeld O, Borri Voltattorni C, Langley D, Roome B, Mackay IR, Christ D, Perahia D, Buckle M, Paiardini A, De Biase D, Buckle AM. Kass I, et al. Among authors: paiardini a. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2524-9. doi: 10.1073/pnas.1403182111. Epub 2014 Jun 9. Proc Natl Acad Sci U S A. 2014. PMID: 24927554 Free PMC article.

70

PLP-dependent enzymes.

Paiardini A, Contestabile R, Buckle AM, Cellini B. Paiardini A, et al. Biomed Res Int. 2014;2014:856076. doi: 10.1155/2014/856076. Epub 2014 Jan 15. Biomed Res Int. 2014. PMID: 24527459 Free PMC article. No abstract available.

71

The phytotoxin fusicoccin differently regulates 14-3-3 proteins association to mode III targets.

Paiardini A, Aducci P, Cervoni L, Cutruzzolà F, Di Lucente C, Janson G, Pascarella S, Rinaldo S, Visconti S, Camoni L. Paiardini A, et al. IUBMB Life. 2014 Jan;66(1):52-62. doi: 10.1002/iub.1239. Epub 2014 Jan 10. IUBMB Life. 2014. PMID: 24408864 Free article.

72

On the catalytic mechanism and stereospecificity of Escherichia coli L-threonine aldolase.

di Salvo ML, Remesh SG, Vivoli M, Ghatge MS, Paiardini A, D'Aguanno S, Safo MK, Contestabile R. di Salvo ML, et al. Among authors: paiardini a. FEBS J. 2014 Jan;281(1):129-45. doi: 10.1111/febs.12581. Epub 2013 Nov 13. FEBS J. 2014. PMID: 24165453 Free PMC article.

73

Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: clues from the structure of the catalytic domain.

Giardina G, Paiardini A, Fernicola S, Franceschini S, Rinaldo S, Stelitano V, Cutruzzolà F. Giardina G, et al. Among authors: paiardini a. PLoS One. 2013 Nov 22;8(11):e81324. doi: 10.1371/journal.pone.0081324. eCollection 2013. PLoS One. 2013. PMID: 24278422 Free PMC article.

74

Type I pyridoxal 5'-phosphate dependent enzymatic domains embedded within multimodular nonribosomal peptide synthetase and polyketide synthase assembly lines.

Milano T, Paiardini A, Grgurina I, Pascarella S. Milano T, et al. Among authors: paiardini a. BMC Struct Biol. 2013 Oct 23;13:26. doi: 10.1186/1472-6807-13-26. BMC Struct Biol. 2013. PMID: 24148833 Free PMC article.

75

C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG.

Stelitano V, Giardina G, Paiardini A, Castiglione N, Cutruzzolà F, Rinaldo S. Stelitano V, et al. Among authors: paiardini a. PLoS One. 2013 Sep 16;8(9):e74920. doi: 10.1371/journal.pone.0074920. eCollection 2013. PLoS One. 2013. PMID: 24066157 Free PMC article.

76

Crystal structure of the S187F variant of human liver alanine: glyoxylate [corrected] aminotransferase associated with primary hyperoxaluria type I and its functional implications.

Oppici E, Fodor K, Paiardini A, Williams C, Voltattorni CB, Wilmanns M, Cellini B. Oppici E, et al. Among authors: paiardini a. Proteins. 2013 Aug;81(8):1457-65. doi: 10.1002/prot.24300. Epub 2013 Jun 1. Proteins. 2013. PMID: 23589421 Free PMC article.

77

The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability.

Antoniani D, Rossi E, Rinaldo S, Bocci P, Lolicato M, Paiardini A, Raffaelli N, Cutruzzolà F, Landini P. Antoniani D, et al. Among authors: paiardini a. Appl Microbiol Biotechnol. 2013 Aug;97(16):7325-36. doi: 10.1007/s00253-013-4875-0. Epub 2013 Apr 14. Appl Microbiol Biotechnol. 2013. PMID: 23584245

78

Synthesis and structure-activity relationships of phosphonic arginine mimetics as inhibitors of the M1 and M17 aminopeptidases from Plasmodium falciparum.

Kannan Sivaraman K, Paiardini A, Sieńczyk M, Ruggeri C, Oellig CA, Dalton JP, Scammells PJ, Drag M, McGowan S. Kannan Sivaraman K, et al. Among authors: paiardini a. J Med Chem. 2013 Jun 27;56(12):5213-7. doi: 10.1021/jm4005972. Epub 2013 Jun 13. J Med Chem. 2013. PMID: 23713488 Free article.

79

Glycine consumption and mitochondrial serine hydroxymethyltransferase in cancer cells: the heme connection.

di Salvo ML, Contestabile R, Paiardini A, Maras B. di Salvo ML, et al. Among authors: paiardini a. Med Hypotheses. 2013 May;80(5):633-6. doi: 10.1016/j.mehy.2013.02.008. Epub 2013 Mar 6. Med Hypotheses. 2013. PMID: 23474074

80

Structural mimicry between SLA/LP and Rickettsia surface antigens as a driver of autoimmune hepatitis: insights from an in silico study.

Paiardini A, Pascarella S. Paiardini A, et al. Theor Biol Med Model. 2013 Apr 10;10:25. doi: 10.1186/1742-4682-10-25. Theor Biol Med Model. 2013. PMID: 23575112 Free PMC article.

81

Chemogenomics of pyridoxal 5'-phosphate dependent enzymes.

Singh R, Spyrakis F, Cozzini P, Paiardini A, Pascarella S, Mozzarelli A. Singh R, et al. Among authors: paiardini a. J Enzyme Inhib Med Chem. 2013 Feb;28(1):183-94. doi: 10.3109/14756366.2011.643305. Epub 2011 Dec 19. J Enzyme Inhib Med Chem. 2013. PMID: 22181815

82

Alanine racemase from Tolypocladium inflatum: a key PLP-dependent enzyme in cyclosporin biosynthesis and a model of catalytic promiscuity.

di Salvo ML, Florio R, Paiardini A, Vivoli M, D'Aguanno S, Contestabile R. di Salvo ML, et al. Among authors: paiardini a. Arch Biochem Biophys. 2013 Jan 15;529(2):55-65. doi: 10.1016/j.abb.2012.11.011. Epub 2012 Dec 3. Arch Biochem Biophys. 2013. PMID: 23219598

83

Insight into the structure-function relationship of the nonheme iron halogenases involved in the biosynthesis of 4-chlorothreonine --Thr3 from Streptomyces sp. OH-5093 and SyrB2 from Pseudomonas syringae pv. syringae B301DR.

Fullone MR, Paiardini A, Miele R, Marsango S, Gross DC, Omura S, Ros-Herrera E, Bonaccorsi di Patti MC, Laganà A, Pascarella S, Grgurina I. Fullone MR, et al. Among authors: paiardini a. FEBS J. 2012 Dec;279(23):4269-82. doi: 10.1111/febs.12017. Epub 2012 Oct 30. FEBS J. 2012. PMID: 23025743 Free article.

84

Rapid profiling of disease alleles using a tunable reporter of protein misfolding.

Pittman AM, Lage MD, Poltoratsky V, Vrana JD, Paiardini A, Roncador A, Cellini B, Hughes RM, Tucker CL. Pittman AM, et al. Among authors: paiardini a. Genetics. 2012 Nov;192(3):831-42. doi: 10.1534/genetics.112.143750. Epub 2012 Aug 24. Genetics. 2012. PMID: 22923379 Free PMC article.

85

PyMod: sequence similarity searches, multiple sequence-structure alignments, and homology modeling within PyMOL.

Bramucci E, Paiardini A, Bossa F, Pascarella S. Bramucci E, et al. Among authors: paiardini a. BMC Bioinformatics. 2012 Mar 28;13 Suppl 4(Suppl 4):S2. doi: 10.1186/1471-2105-13-S4-S2. BMC Bioinformatics. 2012. PMID: 22536966 Free PMC article.

86

Identification by virtual screening and in vitro testing of human DOPA decarboxylase inhibitors.

Daidone F, Montioli R, Paiardini A, Cellini B, Macchiarulo A, Giardina G, Bossa F, Borri Voltattorni C. Daidone F, et al. Among authors: paiardini a. PLoS One. 2012;7(2):e31610. doi: 10.1371/journal.pone.0031610. Epub 2012 Feb 23. PLoS One. 2012. PMID: 22384042 Free PMC article.

87

Molecular insights into primary hyperoxaluria type 1 pathogenesis.

Cellini B, Oppici E, Paiardini A, Montioli R. Cellini B, et al. Among authors: paiardini a. Front Biosci (Landmark Ed). 2012 Jan 1;17(2):621-34. doi: 10.2741/3948. Front Biosci (Landmark Ed). 2012. PMID: 22201765 Free article. Review.

88

Structural adaptation of extreme halophilic proteins through decrease of conserved hydrophobic contact surface.

Siglioccolo A, Paiardini A, Piscitelli M, Pascarella S. Siglioccolo A, et al. Among authors: paiardini a. BMC Struct Biol. 2011 Dec 22;11:50. doi: 10.1186/1472-6807-11-50. BMC Struct Biol. 2011. PMID: 22192175 Free PMC article.

89

Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.

Giardina G, Montioli R, Gianni S, Cellini B, Paiardini A, Voltattorni CB, Cutruzzolà F. Giardina G, et al. Among authors: paiardini a. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20514-9. doi: 10.1073/pnas.1111456108. Epub 2011 Dec 5. Proc Natl Acad Sci U S A. 2011. PMID: 22143761 Free PMC article.

90

In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed.

Daidone F, Florio R, Rinaldo S, Contestabile R, di Salvo ML, Cutruzzolà F, Bossa F, Paiardini A. Daidone F, et al. Among authors: paiardini a. Eur J Med Chem. 2011 May;46(5):1616-21. doi: 10.1016/j.ejmech.2011.02.009. Epub 2011 Mar 2. Eur J Med Chem. 2011. PMID: 21371789

91

Expression of Bv8 in Pichia pastoris to identify structural features for receptor binding.

Miele R, Lattanzi R, Bonaccorsi di Patti MC, Paiardini A, Negri L, Barra D. Miele R, et al. Among authors: paiardini a. Protein Expr Purif. 2010 Sep;73(1):10-4. doi: 10.1016/j.pep.2010.04.012. Epub 2010 Apr 19. Protein Expr Purif. 2010. PMID: 20412858

92

Molecular defects of the glycine 41 variants of alanine glyoxylate aminotransferase associated with primary hyperoxaluria type I.

Cellini B, Montioli R, Paiardini A, Lorenzetto A, Maset F, Bellini T, Oppici E, Voltattorni CB. Cellini B, et al. Among authors: paiardini a. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):2896-901. doi: 10.1073/pnas.0908565107. Epub 2010 Feb 1. Proc Natl Acad Sci U S A. 2010. PMID: 20133649 Free PMC article.

93

Structural stability of the cofactor binding site in Escherichia coli serine hydroxymethyltransferase--the role of evolutionarily conserved hydrophobic contacts.

Florio R, Chiaraluce R, Consalvi V, Paiardini A, Catacchio B, Bossa F, Contestabile R. Florio R, et al. Among authors: paiardini a. FEBS J. 2009 Dec;276(24):7319-28. doi: 10.1111/j.1742-4658.2009.07442.x. FEBS J. 2009. PMID: 19909338 Free article.

94

Structural analysis of toxic volkensin, a type 2 ribosome inactivating protein from Adenia volkensii Harm (kilyambiti plant): molecular modeling and surface analysis by computational methods and limited proteolysis.

Severino V, Paiardini A, Pascarella S, Parente A, Chambery A. Severino V, et al. Among authors: paiardini a. Int J Biol Macromol. 2009 Nov 1;45(4):407-13. doi: 10.1016/j.ijbiomac.2009.06.015. Epub 2009 Jul 8. Int J Biol Macromol. 2009. PMID: 19591862

95

Molecular Insight into the Synergism between the Minor Allele of Human Liver Peroxisomal Alanine:Glyoxylate Aminotransferase and the F152I Mutation.

Cellini B, Montioli R, Paiardini A, Lorenzetto A, Voltattorni CB. Cellini B, et al. Among authors: paiardini a. J Biol Chem. 2009 Mar 27;284(13):8349-58. doi: 10.1074/jbc.M808965200. Epub 2009 Jan 20. J Biol Chem. 2009. PMID: 19155213 Free PMC article.

96

An engineered folded PLP-bound monomer of Treponema denticola cystalysin reveals the effect of the dimeric structure on the catalytic properties of the enzyme.

Montioli R, Cellini B, Bertoldi M, Paiardini A, Voltattorni CB. Montioli R, et al. Among authors: paiardini a. Proteins. 2009 Feb 1;74(2):304-17. doi: 10.1002/prot.22160. Proteins. 2009. PMID: 18618696

97

The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase.

Florio R, Chiaraluce R, Consalvi V, Paiardini A, Catacchio B, Bossa F, Contestabile R. Florio R, et al. Among authors: paiardini a. FEBS J. 2009 Jan;276(1):132-43. doi: 10.1111/j.1742-4658.2008.06761.x. FEBS J. 2009. PMID: 19019081 Free article.

98

Reactions of human liver peroxisomal alanine:glyoxylate aminotransferase with beta-chloro-L-alanine and L-cysteine: spectroscopic and kinetic analysis.

Bertoldi M, Cellini B, Paiardini A, Montioli R, Borri Voltattorni C. Bertoldi M, et al. Among authors: paiardini a. Biochim Biophys Acta. 2008 Sep;1784(9):1356-62. doi: 10.1016/j.bbapap.2008.04.013. Epub 2008 May 1. Biochim Biophys Acta. 2008. PMID: 18492492

99

Insights into the interaction of sortilin with proneurotrophins: a computational approach.

Paiardini A, Caputo V. Paiardini A, et al. Neuropeptides. 2008 Apr;42(2):205-14. doi: 10.1016/j.npep.2007.11.004. Epub 2008 Jan 8. Neuropeptides. 2008. PMID: 18191449

100

"Hot cores" in proteins: comparative analysis of the apolar contact area in structures from hyper/thermophilic and mesophilic organisms.

Paiardini A, Sali R, Bossa F, Pascarella S. Paiardini A, et al. BMC Struct Biol. 2008 Feb 29;8:14. doi: 10.1186/1472-6807-8-14. BMC Struct Biol. 2008. PMID: 18312638 Free PMC article.

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