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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 1
2003 3
2004 2
2005 1
2006 2
2007 2
2008 3
2009 5
2010 2
2011 4
2012 6
2013 11
2014 6
2015 9
2016 7
2017 12
2018 10
2019 6
2020 10
2021 6
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100 results
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Page 1
A Single Center Retrospective Review of Patients from Central Italy Tested for Melanoma Predisposition Genes.
De Simone P, Bottillo I, Valiante M, Iorio A, De Bernardo C, Majore S, D'Angelantonio D, Valentini T, Sperduti I, Piemonte P, Eibenschutz L, Ferrari A, Carbone A, Buccini P, Paiardini A, Silipo V, Frascione P, Grammatico P. De Simone P, et al. Among authors: paiardini a. Int J Mol Sci. 2020 Dec 11;21(24):9432. doi: 10.3390/ijms21249432. Int J Mol Sci. 2020. PMID: 33322357 Free PMC article.
Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity.
Bouzidi A, Magnifico MC, Paiardini A, Macone A, Boumis G, Giardina G, Rinaldo S, Liberati FR, Lauro C, Limatola C, Lanzillotta C, Tramutola A, Perluigi M, Sgarbi G, Solaini G, Baracca A, Paone A, Cutruzzolà F. Bouzidi A, et al. Among authors: paiardini a. Cell Death Dis. 2020 Nov 26;11(11):1012. doi: 10.1038/s41419-020-03215-0. Cell Death Dis. 2020. PMID: 33243973 Free PMC article.
Artemisinin Derivatives with Antimelanoma Activity Show Inhibitory Effect against Human DNA Topoisomerase 1.
Botta L, Filippi S, Zippilli C, Cesarini S, Bizzarri BM, Cirigliano A, Rinaldi T, Paiardini A, Fiorucci D, Saladino R, Negri R, Benedetti P. Botta L, et al. Among authors: paiardini a. ACS Med Chem Lett. 2020 Apr 10;11(5):1035-1040. doi: 10.1021/acsmedchemlett.0c00131. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435422 Free PMC article.
From PARP1 to TNKS2 Inhibition: A Structure-Based Approach.
Tomassi S, Pfahler J, Mautone N, Rovere A, Esposito C, Passeri D, Pellicciari R, Novellino E, Pannek M, Steegborn C, Paiardini A, Mai A, Rotili D. Tomassi S, et al. Among authors: paiardini a. ACS Med Chem Lett. 2020 Feb 3;11(5):862-868. doi: 10.1021/acsmedchemlett.9b00654. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435397 Free PMC article.
Insights into PPARγ Phosphorylation and Its Inhibition Mechanism.
Montanari R, Capelli D, Yamamoto K, Awaishima H, Nishikata K, Barendregt A, Heck AJR, Loiodice F, Altieri F, Paiardini A, Grottesi A, Pirone L, Pedone E, Peiretti F, Brunel JM, Itoh T, Pochetti G. Montanari R, et al. Among authors: paiardini a. J Med Chem. 2020 May 14;63(9):4811-4823. doi: 10.1021/acs.jmedchem.0c00048. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32239932 Free article.
Prenatal whole exome sequencing detects a new homozygous fukutin (FKTN) mutation in a fetus with an ultrasound suspicion of familial Dandy-Walker malformation.
Traversa A, Bernardo S, Paiardini A, Giovannetti A, Marchionni E, Genovesi ML, Guadagnolo D, Torres B, Paolacci S, Bernardini L, Mazza T, Carella M, Caputo V, Pizzuti A. Traversa A, et al. Among authors: paiardini a. Mol Genet Genomic Med. 2020 Jan;8(1):e1054. doi: 10.1002/mgg3.1054. Epub 2019 Nov 22. Mol Genet Genomic Med. 2020. PMID: 31756055 Free PMC article.
The moonlighting RNA-binding activity of cytosolic serine hydroxymethyltransferase contributes to control compartmentalization of serine metabolism.
Guiducci G, Paone A, Tramonti A, Giardina G, Rinaldo S, Bouzidi A, Magnifico MC, Marani M, Menendez JA, Fatica A, Macone A, Armaos A, Tartaglia GG, Contestabile R, Paiardini A, Cutruzzolà F. Guiducci G, et al. Among authors: paiardini a. Nucleic Acids Res. 2019 May 7;47(8):4240-4254. doi: 10.1093/nar/gkz129. Nucleic Acids Res. 2019. PMID: 30809670 Free PMC article.
Corrigendum to "Pyridoxine-5'-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g>A (P.·Arg116gln) mutation" [Mol. Genet. Metab. 122/1-2 (2017) 135-142].
di Salvo ML, Mastrangelo M, Nogués I, Tolve M, Paiardini A, Carducci C, Mei D, Montomoli M, Tramonti A, Guerrini R, Contestabile R, Leuzzi V. di Salvo ML, et al. Among authors: paiardini a. Mol Genet Metab. 2018 Dec;125(4):359. doi: 10.1016/j.ymgme.2018.02.017. Epub 2018 Mar 14. Mol Genet Metab. 2018. PMID: 29548777 No abstract available.
Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa.
Mantoni F, Paiardini A, Brunotti P, D'Angelo C, Cervoni L, Paone A, Cappellacci L, Petrelli R, Ricciutelli M, Leoni L, Rampioni G, Arcovito A, Rinaldo S, Cutruzzolà F, Giardina G. Mantoni F, et al. Among authors: paiardini a. FEBS J. 2018 Oct;285(20):3815-3834. doi: 10.1111/febs.14634. Epub 2018 Sep 7. FEBS J. 2018. PMID: 30106221 Free article.
The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.
Giardina G, Paone A, Tramonti A, Lucchi R, Marani M, Magnifico MC, Bouzidi A, Pontecorvi V, Guiducci G, Zamparelli C, Rinaldo S, Paiardini A, Contestabile R, Cutruzzolà F. Giardina G, et al. Among authors: paiardini a. FEBS J. 2018 Sep;285(17):3238-3253. doi: 10.1111/febs.14610. Epub 2018 Aug 7. FEBS J. 2018. PMID: 30035852 Free article.
A novel germline mutation in CDK4 codon 24 associated to familial melanoma.
Bottillo I, La Starza R, Radio FC, Molica C, Pedace L, Pierini T, De Bernardo C, Stingeni L, Bargiacchi S, Paiardini A, Janson G, Mecucci C, Grammatico P. Bottillo I, et al. Among authors: paiardini a. Clin Genet. 2018 Apr;93(4):934-935. doi: 10.1111/cge.13129. Epub 2017 Nov 10. Clin Genet. 2018. PMID: 29124743 No abstract available.
Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7γ.
Di Matteo A, Franceschini M, Paiardini A, Grottesi A, Chiarella S, Rocchio S, Di Natale C, Marasco D, Vitagliano L, Travaglini-Allocatelli C, Federici L. Di Matteo A, et al. Among authors: paiardini a. Oncogenesis. 2017 Sep 18;6(9):e379. doi: 10.1038/oncsis.2017.78. Oncogenesis. 2017. PMID: 28920929 Free PMC article.
Pyridoxine-5'-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g>A (P.·Arg116gln) mutation.
di Salvo ML, Mastrangelo M, Nogués I, Tolve M, Paiardini A, Carducci C, Mei D, Montomoli M, Tramonti A, Guerrini R, Contestabile R, Leuzzi V. di Salvo ML, et al. Among authors: paiardini a. Mol Genet Metab. 2017 Sep;122(1-2):135-142. doi: 10.1016/j.ymgme.2017.08.003. Epub 2017 Aug 12. Mol Genet Metab. 2017. PMID: 28818555
Identification of small molecule inhibitors of the Aurora-A/TPX2 complex.
Asteriti IA, Daidone F, Colotti G, Rinaldo S, Lavia P, Guarguaglini G, Paiardini A. Asteriti IA, et al. Among authors: paiardini a. Oncotarget. 2017 May 9;8(19):32117-32133. doi: 10.18632/oncotarget.16738. Oncotarget. 2017. PMID: 28389630 Free PMC article.
Glucose Metabolism in the Progression of Prostate Cancer.
Cutruzzolà F, Giardina G, Marani M, Macone A, Paiardini A, Rinaldo S, Paone A. Cutruzzolà F, et al. Among authors: paiardini a. Front Physiol. 2017 Feb 21;8:97. doi: 10.3389/fphys.2017.00097. eCollection 2017. Front Physiol. 2017. PMID: 28270771 Free PMC article. Review.
Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming.
Paiardini A, Tramonti A, Schirch D, Guiducci G, di Salvo ML, Fiascarelli A, Giorgi A, Maras B, Cutruzzolà F, Contestabile R. Paiardini A, et al. Biochim Biophys Acta. 2016 Nov;1864(11):1506-17. doi: 10.1016/j.bbapap.2016.08.010. Epub 2016 Aug 13. Biochim Biophys Acta. 2016. PMID: 27530298
Prediction and visualization data for the interpretation of sarcomeric and non-sarcomeric DNA variants found in patients with hypertrophic cardiomyopathy.
Bottillo I, D'Angelantonio D, Caputo V, Paiardini A, Lipari M, De Bernardo C, Majore S, Castori M, Zachara E, Re F, Grammatico P. Bottillo I, et al. Among authors: paiardini a. Data Brief. 2016 Mar 10;7:607-13. doi: 10.1016/j.dib.2016.03.004. eCollection 2016 Jun. Data Brief. 2016. PMID: 27054166 Free PMC article.
A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.
Marani M, Paone A, Fiascarelli A, Macone A, Gargano M, Rinaldo S, Giardina G, Pontecorvi V, Koes D, McDermott L, Yang T, Paiardini A, Contestabile R, Cutruzzolà F. Marani M, et al. Among authors: paiardini a. Oncotarget. 2016 Jan 26;7(4):4570-83. doi: 10.18632/oncotarget.6726. Oncotarget. 2016. PMID: 26717037 Free PMC article.
Structural basis of functional diversification of the HD-GYP domain revealed by the Pseudomonas aeruginosa PA4781 protein, which displays an unselective bimetallic binding site.
Rinaldo S, Paiardini A, Stelitano V, Brunotti P, Cervoni L, Fernicola S, Protano C, Vitali M, Cutruzzolà F, Giardina G. Rinaldo S, et al. Among authors: paiardini a. J Bacteriol. 2015 Apr;197(8):1525-35. doi: 10.1128/JB.02606-14. Epub 2015 Feb 17. J Bacteriol. 2015. PMID: 25691523 Free PMC article.
How pyridoxal 5'-phosphate differentially regulates human cytosolic and mitochondrial serine hydroxymethyltransferase oligomeric state.
Giardina G, Brunotti P, Fiascarelli A, Cicalini A, Costa MG, Buckle AM, di Salvo ML, Giorgi A, Marani M, Paone A, Rinaldo S, Paiardini A, Contestabile R, Cutruzzolà F. Giardina G, et al. Among authors: paiardini a. FEBS J. 2015 Apr;282(7):1225-41. doi: 10.1111/febs.13211. Epub 2015 Feb 13. FEBS J. 2015. PMID: 25619277 Free article.
Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis.
Kass I, Hoke DE, Costa MG, Reboul CF, Porebski BT, Cowieson NP, Leh H, Pennacchietti E, McCoey J, Kleifeld O, Borri Voltattorni C, Langley D, Roome B, Mackay IR, Christ D, Perahia D, Buckle M, Paiardini A, De Biase D, Buckle AM. Kass I, et al. Among authors: paiardini a. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):E2524-9. doi: 10.1073/pnas.1403182111. Epub 2014 Jun 9. Proc Natl Acad Sci U S A. 2014. PMID: 24927554 Free PMC article.
PLP-dependent enzymes.
Paiardini A, Contestabile R, Buckle AM, Cellini B. Paiardini A, et al. Biomed Res Int. 2014;2014:856076. doi: 10.1155/2014/856076. Epub 2014 Jan 15. Biomed Res Int. 2014. PMID: 24527459 Free PMC article. No abstract available.
The immunosuppressive drug azathioprine inhibits biosynthesis of the bacterial signal molecule cyclic-di-GMP by interfering with intracellular nucleotide pool availability.
Antoniani D, Rossi E, Rinaldo S, Bocci P, Lolicato M, Paiardini A, Raffaelli N, Cutruzzolà F, Landini P. Antoniani D, et al. Among authors: paiardini a. Appl Microbiol Biotechnol. 2013 Aug;97(16):7325-36. doi: 10.1007/s00253-013-4875-0. Epub 2013 Apr 14. Appl Microbiol Biotechnol. 2013. PMID: 23584245
Chemogenomics of pyridoxal 5'-phosphate dependent enzymes.
Singh R, Spyrakis F, Cozzini P, Paiardini A, Pascarella S, Mozzarelli A. Singh R, et al. Among authors: paiardini a. J Enzyme Inhib Med Chem. 2013 Feb;28(1):183-94. doi: 10.3109/14756366.2011.643305. Epub 2011 Dec 19. J Enzyme Inhib Med Chem. 2013. PMID: 22181815
Insight into the structure-function relationship of the nonheme iron halogenases involved in the biosynthesis of 4-chlorothreonine --Thr3 from Streptomyces sp. OH-5093 and SyrB2 from Pseudomonas syringae pv. syringae B301DR.
Fullone MR, Paiardini A, Miele R, Marsango S, Gross DC, Omura S, Ros-Herrera E, Bonaccorsi di Patti MC, Laganà A, Pascarella S, Grgurina I. Fullone MR, et al. Among authors: paiardini a. FEBS J. 2012 Dec;279(23):4269-82. doi: 10.1111/febs.12017. Epub 2012 Oct 30. FEBS J. 2012. PMID: 23025743 Free article.
Molecular insights into primary hyperoxaluria type 1 pathogenesis.
Cellini B, Oppici E, Paiardini A, Montioli R. Cellini B, et al. Among authors: paiardini a. Front Biosci (Landmark Ed). 2012 Jan 1;17:621-34. doi: 10.2741/3948. Front Biosci (Landmark Ed). 2012. PMID: 22201765 Free article. Review.
Structural analysis of toxic volkensin, a type 2 ribosome inactivating protein from Adenia volkensii Harm (kilyambiti plant): molecular modeling and surface analysis by computational methods and limited proteolysis.
Severino V, Paiardini A, Pascarella S, Parente A, Chambery A. Severino V, et al. Among authors: paiardini a. Int J Biol Macromol. 2009 Nov 1;45(4):407-13. doi: 10.1016/j.ijbiomac.2009.06.015. Epub 2009 Jul 8. Int J Biol Macromol. 2009. PMID: 19591862