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1997 1
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254 results

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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
A Randomized, Double-Blind, Multicenter, Noninferiority Study Comparing Paliperidone Palmitate 6-Month Versus the 3-Month Long-Acting Injectable in Patients With Schizophrenia.
Najarian D, Sanga P, Wang S, Lim P, Singh A, Robertson MJ, Cohen K, Schotte A, Milz R, Venkatasubramanian R, T'Jollyn H, Walling DP, Galderisi S, Gopal S. Najarian D, et al. Int J Neuropsychopharmacol. 2022 Mar 17;25(3):238-251. doi: 10.1093/ijnp/pyab071. Int J Neuropsychopharmacol. 2022. PMID: 34791283 Free PMC article. Clinical Trial.
BACKGROUND: This double-blind (DB), randomized, parallel-group study was designed to evaluate efficacy and safety of paliperidone palmitate 6-month (PP6M) formulation relative to paliperidone palmitate 3-month (PP3M) formulation in patients with schizo …
BACKGROUND: This double-blind (DB), randomized, parallel-group study was designed to evaluate efficacy and safety of paliperidone …
Paliperidone for schizophrenia.
Nussbaum A, Stroup TS. Nussbaum A, et al. Cochrane Database Syst Rev. 2008 Apr 16;2008(2):CD006369. doi: 10.1002/14651858.CD006369.pub2. Cochrane Database Syst Rev. 2008. PMID: 18425951 Free PMC article.
MAIN RESULTS: Five studies compared paliperidone with placebo. Fewer people left the studies early if they were randomized to paliperidone (n=1647, 5 RCTs, RR 0.68 CI 0.61 to 0.76, NNT 7 CI 6 to 9) and those receiving any dose of paliperidone were significant …
MAIN RESULTS: Five studies compared paliperidone with placebo. Fewer people left the studies early if they were randomized to pali …
Paliperidone palmitate for schizophrenia.
Nussbaum AM, Stroup TS. Nussbaum AM, et al. Cochrane Database Syst Rev. 2012 Jun 13;2012(6):CD008296. doi: 10.1002/14651858.CD008296.pub2. Cochrane Database Syst Rev. 2012. PMID: 22696377 Free PMC article.
BACKGROUND: Paliperidone palmitate, a long-acting, intramuscular formulation of paliperidone, is now available for clinical use. ...MAIN RESULTS: Five studies with 2215 participants compared paliperidone palmitate with placebo. Fewer people left …
BACKGROUND: Paliperidone palmitate, a long-acting, intramuscular formulation of paliperidone, is now available for clin …
Paliperidone palmitate for schizophrenia.
Nussbaum AM, Stroup TS. Nussbaum AM, et al. Schizophr Bull. 2012 Nov;38(6):1124-7. doi: 10.1093/schbul/sbs099. Epub 2012 Sep 10. Schizophr Bull. 2012. PMID: 22966147 Free PMC article. Review. No abstract available.
Paliperidone palmitate vs. paliperidone extended-release for the acute treatment of adults with schizophrenia: a systematic review and pairwise and network meta-analysis.
Kishi T, Sakuma K, Iwata N. Kishi T, et al. Transl Psychiatry. 2022 Dec 19;12(1):519. doi: 10.1038/s41398-022-02286-1. Transl Psychiatry. 2022. PMID: 36535950 Free PMC article.
Is paliperidone palmitate (PP) a useful treatment option for adults with acute symptoms of schizophrenia? We conducted a systematic review and a random-effects pairwise and network meta-analysis that compared PP (25-150 mg equivalent) with paliperidone extend …
Is paliperidone palmitate (PP) a useful treatment option for adults with acute symptoms of schizophrenia? We conducted a syste …
Comparative efficacy and tolerability of 32 oral antipsychotics for the acute treatment of adults with multi-episode schizophrenia: a systematic review and network meta-analysis.
Huhn M, Nikolakopoulou A, Schneider-Thoma J, Krause M, Samara M, Peter N, Arndt T, Bäckers L, Rothe P, Cipriani A, Davis J, Salanti G, Leucht S. Huhn M, et al. Lancet. 2019 Sep 14;394(10202):939-951. doi: 10.1016/S0140-6736(19)31135-3. Epub 2019 Jul 11. Lancet. 2019. PMID: 31303314 Free PMC article.
Mean differences compared to placebo for weight gain (28 317 participants) ranged from -0.16 kg (-0.73 to 0.40; ziprasidone) to 3.21 kg (2.10 to 4.31; zotepine), for prolactin elevation (21 569 participants) from -77.05 ng/mL (-120.23 to -33.54; clozapine) to 48.51 ng/mL (43.52 t …
Mean differences compared to placebo for weight gain (28 317 participants) ranged from -0.16 kg (-0.73 to 0.40; ziprasidone) to 3.21 kg (2.1 …
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis.
Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, Samara M, Barbui C, Engel RR, Geddes JR, Kissling W, Stapf MP, Lässig B, Salanti G, Davis JM. Leucht S, et al. Lancet. 2013 Sep 14;382(9896):951-62. doi: 10.1016/S0140-6736(13)60733-3. Epub 2013 Jun 27. Lancet. 2013. PMID: 23810019 Review.
The standardised mean differences with 95% credible intervals were: clozapine 0.88, 0.73-1.03; amisulpride 0.66, 0.53-0.78; olanzapine 0.59, 0.53-0.65; risperidone 0.56, 0.50-0.63; paliperidone 0.50, 0.39-0.60; zotepine 0.49, 0.31-0.66; haloperidol 0.45, 0.39-0.51; quetiap …
The standardised mean differences with 95% credible intervals were: clozapine 0.88, 0.73-1.03; amisulpride 0.66, 0.53-0.78; olanzapine 0.59, …
Dose-Response Meta-Analysis of Antipsychotic Drugs for Acute Schizophrenia.
Leucht S, Crippa A, Siafis S, Patel MX, Orsini N, Davis JM. Leucht S, et al. Am J Psychiatry. 2020 Apr 1;177(4):342-353. doi: 10.1176/appi.ajp.2019.19010034. Epub 2019 Dec 16. Am J Psychiatry. 2020. PMID: 31838873
The 95% effective doses and the doses equivalent to 1 mg of oral risperidone, respectively, were as follows: amisulpride for patients with positive symptoms, 537 mg/day and 85.8 mg; aripiprazole, 11.5 mg/day and 1.8 mg; aripiprazole LAI (lauroxil), 463 mg every 4 weeks and 264 mg …
The 95% effective doses and the doses equivalent to 1 mg of oral risperidone, respectively, were as follows: amisulpride for patients with p …
The efficacy and tolerability of paliperidone in mania of bipolar disorder: A preliminary meta-analysis.
Chang HY, Tseng PT, Stubbs B, Chu CS, Li DJ, Fornaro M, Carvalho A, Solmi M, Veronese N, Vieta E, Chen TY, Chen YW, Lin PY, Chow PC. Chang HY, et al. Exp Clin Psychopharmacol. 2017 Oct;25(5):422-433. doi: 10.1037/pha0000148. Exp Clin Psychopharmacol. 2017. PMID: 29048190 Review.
Paliperidone may be effective for the treatment of bipolar disorder (BD); however, the evidence has been mixed. ...We then performed exploratory random-effects meta-analysis. The 3 included RCTs compared paliperidone with placebo (667 patients received paliperido …
Paliperidone may be effective for the treatment of bipolar disorder (BD); however, the evidence has been mixed. ...We then performed …
Pharmacological treatment for bipolar mania: a systematic review and network meta-analysis of double-blind randomized controlled trials.
Kishi T, Ikuta T, Matsuda Y, Sakuma K, Okuya M, Nomura I, Hatano M, Iwata N. Kishi T, et al. Mol Psychiatry. 2022 Feb;27(2):1136-1144. doi: 10.1038/s41380-021-01334-4. Epub 2021 Oct 12. Mol Psychiatry. 2022. PMID: 34642461 Free PMC article.
Compared with the placebo, aripiprazole, asenapine, carbamazepine, cariprazine, haloperidol, lithium, olanzapine, paliperidone, quetiapine, risperidone, tamoxifen, valproate, and ziprasidone outperformed response to treatment (N = 56, n = 14503); aripiprazole, olanzapine, …
Compared with the placebo, aripiprazole, asenapine, carbamazepine, cariprazine, haloperidol, lithium, olanzapine, paliperidone, queti …
254 results