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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1969 2
1970 2
1971 5
1972 3
1973 5
1974 5
1975 1
1976 2
1977 8
1978 6
1979 4
1980 2
1981 6
1982 5
1983 4
1984 3
1985 6
1986 2
1987 5
1988 4
1989 9
1990 9
1991 5
1992 10
1993 3
1994 6
1995 10
1996 15
1997 22
1998 19
1999 31
2000 33
2001 29
2002 49
2003 48
2004 44
2005 53
2006 49
2007 60
2008 55
2009 54
2010 64
2011 78
2012 82
2013 86
2014 86
2015 98
2016 100
2017 104
2018 93
2019 98
2020 234
2021 281
2022 238
2023 157
2024 118

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Search Results

2,338 results

Results by year

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Page 1
Evidence for association between hepatitis C virus and Parkinson's disease.
Abushouk AI, El-Husseny MWA, Magdy M, Ismail A, Attia A, Ahmed H, Pallanti R, Negida A. Abushouk AI, et al. Neurol Sci. 2017 Nov;38(11):1913-1920. doi: 10.1007/s10072-017-3077-4. Epub 2017 Aug 5. Neurol Sci. 2017. PMID: 28780707 Review.
Parkinson's disease (PD) is a globally prevalent neurodegenerative disorder, characterized by progressive neuronal loss in the substantia nigra and formation of Lewy bodies. ...Emerging data from epidemiological studies suggest a possible association between …
Parkinson's disease (PD) is a globally prevalent neurodegenerative disorder, characterized by progressive neuronal loss …
Hepatitis C virus infection and risk of Parkinson's disease: a systematic review and meta-analysis.
Wijarnpreecha K, Chesdachai S, Jaruvongvanich V, Ungprasert P. Wijarnpreecha K, et al. Eur J Gastroenterol Hepatol. 2018 Jan;30(1):9-13. doi: 10.1097/MEG.0000000000000991. Eur J Gastroenterol Hepatol. 2018. PMID: 29049127 Review.
BACKGROUND/OBJECTIVE: Hepatitis C virus (HCV) infection is one of the most common infections worldwide. Recent epidemiologic studies have suggested that patients with HCV infection might be at an increased risk of Parkinson's disease. ...Studies that r …
BACKGROUND/OBJECTIVE: Hepatitis C virus (HCV) infection is one of the most common infections worldwide. Recent epidemiologic studies …
Parkinson's Disease: A Prionopathy?
Vascellari S, Manzin A. Vascellari S, et al. Int J Mol Sci. 2021 Jul 27;22(15):8022. doi: 10.3390/ijms22158022. Int J Mol Sci. 2021. PMID: 34360787 Free PMC article. Review.
The principal pathogenic event in Parkinson's disease is characterized by the conformational change of alpha-synuclein, which form pathological aggregates of misfolded proteins, and then accumulate in intraneuronal inclusions causing dopaminergic neuronal los …
The principal pathogenic event in Parkinson's disease is characterized by the conformational change of alpha-synuclein, …
GalNAc-siRNA Conjugates: Leading the Way for Delivery of RNAi Therapeutics.
Springer AD, Dowdy SF. Springer AD, et al. Nucleic Acid Ther. 2018 Jun;28(3):109-118. doi: 10.1089/nat.2018.0736. Epub 2018 May 24. Nucleic Acid Ther. 2018. PMID: 29792572 Free PMC article. Review.
Short-interfering RNA (siRNA)-induced RNAi responses have great potential to treat a wide variety of human diseases from cancer to pandemic viral outbreaks to Parkinson's Disease. However, before siRNAs can become drugs, they must overcome a billion years of …
Short-interfering RNA (siRNA)-induced RNAi responses have great potential to treat a wide variety of human diseases from cancer to pandemic …
BBB opening with focused ultrasound in nonhuman primates and Parkinson's disease patients: Targeted AAV vector delivery and PET imaging.
Blesa J, Pineda-Pardo JA, Inoue KI, Gasca-Salas C, Balzano T, Del Rey NL, Reinares-Sebastián A, Esteban-García N, Rodríguez-Rojas R, Márquez R, Ciorraga M, Del Álamo M, García-Cañamaque L, Ruiz de Aguiar S, Rachmilevitch I, Trigo-Damas I, Takada M, Obeso JA. Blesa J, et al. Sci Adv. 2023 Apr 21;9(16):eadf4888. doi: 10.1126/sciadv.adf4888. Epub 2023 Apr 19. Sci Adv. 2023. PMID: 37075119 Free PMC article.
We report successful blood-brain barrier opening and focal delivery of adeno-associated virus serotype 9 vectors into brain regions involved in Parkinson's disease using low-intensity focus ultrasound in adult macaque monkeys. ...Similar blood-brain ba …
We report successful blood-brain barrier opening and focal delivery of adeno-associated virus serotype 9 vectors into brain regions i …
Human iPSC-derived midbrain organoids functionally integrate into striatum circuits and restore motor function in a mouse model of Parkinson's disease.
Zheng X, Han D, Liu W, Wang X, Pan N, Wang Y, Chen Z. Zheng X, et al. Theranostics. 2023 Apr 29;13(8):2673-2692. doi: 10.7150/thno.80271. eCollection 2023. Theranostics. 2023. PMID: 37215566 Free PMC article.
Rationale: Parkinson's disease (PD) is a prevalent neurodegenerative disorder that is characterized by degeneration of dopaminergic neurons (DA) at the substantia nigra pas compacta (SNpc). ...Behavioral tests were conducted to evaluate functional restoration …
Rationale: Parkinson's disease (PD) is a prevalent neurodegenerative disorder that is characterized by degeneration of …
Parkinson's disease: gene therapies.
Coune PG, Schneider BL, Aebischer P. Coune PG, et al. Cold Spring Harb Perspect Med. 2012 Apr;2(4):a009431. doi: 10.1101/cshperspect.a009431. Cold Spring Harb Perspect Med. 2012. PMID: 22474617 Free PMC article. Review.
Here, we review existing viral vectors and discuss gene therapy strategies that have been proposed for Parkinson's disease. To date, most of the clinical trials were based on viral vectors to deliver therapeutic transgenes to neurons within the basal ganglia. …
Here, we review existing viral vectors and discuss gene therapy strategies that have been proposed for Parkinson's disease …
AAV2-GDNF gene therapy for Parkinson's disease.
Even Ram S, Galun E. Even Ram S, et al. Hum Gene Ther. 2009 May;20(5):430-1. doi: 10.1089/hum.2009.1599. Hum Gene Ther. 2009. PMID: 19438403 No abstract available.
Disease-modifying strategies for Parkinson's disease.
Kalia LV, Kalia SK, Lang AE. Kalia LV, et al. Mov Disord. 2015 Sep 15;30(11):1442-50. doi: 10.1002/mds.26354. Epub 2015 Jul 24. Mov Disord. 2015. PMID: 26208210 Review.
Parkinson's disease (PD) is an increasingly prevalent and progressively disabling neurodegenerative disease. The impact of PD on patients and their families as well as its burden on health care systems could be substantially reduced by disease-m …
Parkinson's disease (PD) is an increasingly prevalent and progressively disabling neurodegenerative disease. The …
2,338 results