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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
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Efficacy and Safety of 0.6% Pazufloxacin Ophthalmic Solution Versus Moxifloxacin 0.5% and Gatifloxacin 0.5% in Subjects with Bacterial Conjunctivitis: A Randomized Clinical Trial.
Baiza-Durán L, Olvera-Montaño O, Mercado-Sesma AR, Oregon-Miranda AA, Lizárraga-Corona A, Ochoa-Tabares JC, Pérez-Balbuena AL, Montoya-Sánchez IM, Saucedo-Rodríguez LR, Mora-González A, Gómez-Bastar PA, Villanueva-Najera MA, Sandoval-Delgadillo LI, González-Lomelí M, Páez-Garza JH, Orozco-Carroll M, Casillas-Magallanes M. Baiza-Durán L, et al. J Ocul Pharmacol Ther. 2018 Apr;34(3):250-255. doi: 10.1089/jop.2017.0056. Epub 2018 Jan 11. J Ocul Pharmacol Ther. 2018. PMID: 29624493 Clinical Trial.
RESULTS: After intervention, bacterial eradication was reported in all groups: pazufloxacin BID 79%, pazufloxacin TID 84%, pazufloxacin QID 84%, moxifloxacin 80%, and gatifloxacin 82%. ...Similar results were reported in clinical remission: pazufloxacin …
RESULTS: After intervention, bacterial eradication was reported in all groups: pazufloxacin BID 79%, pazufloxacin TID 84%, …
Single-dose pharmacokinetics and dose proportionality of intravenous pazufloxacin mesilate in healthy Korean volunteers.
Lee J, Seong SJ, Lim MS, Park SM, Park J, Seo JJ, Lee HW, Yoon YR. Lee J, et al. Expert Opin Drug Metab Toxicol. 2012 Aug;8(8):921-8. doi: 10.1517/17425255.2012.688951. Expert Opin Drug Metab Toxicol. 2012. PMID: 22809012 Clinical Trial.
At all four dosages studied, pazufloxacin mesilate was well tolerated. CONCLUSIONS: Our data suggest that all regimens of pazufloxacin administration were well tolerated. Pazufloxacin exhibits lack of dose proportionality over the dose range of 300 - 1,000 mg …
At all four dosages studied, pazufloxacin mesilate was well tolerated. CONCLUSIONS: Our data suggest that all regimens of pazuflox …