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Associations of cannabis use disorder with cognition, brain structure, and brain function in African Americans.
Koenis MMG, Durnez J, Rodrigue AL, Mathias SR, Alexander-Bloch AF, Barrett JA, Doucet GE, Frangou S, Knowles EEM, Mollon J, Denbow D, Aberizk K, Zatony M, Janssen RJ, Curran JE, Blangero J, Poldrack RA, Pearlson GD, Glahn DC. Koenis MMG, et al. Among authors: pearlson gd. Hum Brain Mapp. 2021 Apr 15;42(6):1727-1741. doi: 10.1002/hbm.25324. Epub 2020 Dec 19. Hum Brain Mapp. 2021. PMID: 33340172 Free PMC article.
Although previous studies have highlighted associations of cannabis use with cognition and brain morphometry, critical questions remain with regard to the association between cannabis use and brain structural and functional connectivity. In a cross-sectional communi …
Although previous studies have highlighted associations of cannabis use with cognition and brain morphometry, critical questions rema …
Subcortical surface morphometry in substance dependence: An ENIGMA addiction working group study.
Chye Y, Mackey S, Gutman BA, Ching CRK, Batalla A, Blaine S, Brooks S, Caparelli EC, Cousijn J, Dagher A, Foxe JJ, Goudriaan AE, Hester R, Hutchison K, Jahanshad N, Kaag AM, Korucuoglu O, Li CR, London ED, Lorenzetti V, Luijten M, Martin-Santos R, Meda SA, Momenan R, Morales A, Orr C, Paulus MP, Pearlson G, Reneman L, Schmaal L, Sinha R, Solowij N, Stein DJ, Stein EA, Tang D, Uhlmann A, van Holst R, Veltman DJ, Verdejo-Garcia A, Wiers RW, Yücel M, Thompson PM, Conrod P, Garavan H. Chye Y, et al. Among authors: pearlson g. Addict Biol. 2020 Nov;25(6):e12830. doi: 10.1111/adb.12830. Epub 2019 Nov 20. Addict Biol. 2020. PMID: 31746534
By pooling large multinational datasets from 33 imaging sites, this study examined subcortical surface morphology in 1628 nondependent controls and 2277 individuals with dependence on alcohol, nicotine, cocaine, methamphetamine, and/or cannabis. Subcortical structures were …
By pooling large multinational datasets from 33 imaging sites, this study examined subcortical surface morphology in 1628 nondependent contr …
Mega-Analysis of Gray Matter Volume in Substance Dependence: General and Substance-Specific Regional Effects.
Mackey S, Allgaier N, Chaarani B, Spechler P, Orr C, Bunn J, Allen NB, Alia-Klein N, Batalla A, Blaine S, Brooks S, Caparelli E, Chye YY, Cousijn J, Dagher A, Desrivieres S, Feldstein-Ewing S, Foxe JJ, Goldstein RZ, Goudriaan AE, Heitzeg MM, Hester R, Hutchison K, Korucuoglu O, Li CR, London E, Lorenzetti V, Luijten M, Martin-Santos R, May A, Momenan R, Morales A, Paulus MP, Pearlson G, Rousseau ME, Salmeron BJ, Schluter R, Schmaal L, Schumann G, Sjoerds Z, Stein DJ, Stein EA, Sinha R, Solowij N, Tapert S, Uhlmann A, Veltman D, van Holst R, Whittle S, Wright MJ, Yücel M, Zhang S, Yurgelun-Todd D, Hibar DP, Jahanshad N, Evans A, Thompson PM, Glahn DC, Conrod P, Garavan H; ENIGMA Addiction Working Group. Mackey S, et al. Among authors: pearlson g. Am J Psychiatry. 2019 Feb 1;176(2):119-128. doi: 10.1176/appi.ajp.2018.17040415. Epub 2018 Oct 19. Am J Psychiatry. 2019. PMID: 30336705 Free PMC article.
METHOD: Brain structure was examined in a mega-analysis of previously published data pooled from 23 laboratories, including 3,240 individuals, 2,140 of whom had substance dependence on one of five substances: alcohol, nicotine, cocaine, methamphetamine, or cannabis. Subcor …
METHOD: Brain structure was examined in a mega-analysis of previously published data pooled from 23 laboratories, including 3,240 individual …
Relationship between fMRI response during a nonverbal memory task and marijuana use in college students.
Dager AD, Tice MR, Book GA, Tennen H, Raskin SA, Austad CS, Wood RM, Fallahi CR, Hawkins KA, Pearlson GD. Dager AD, et al. Among authors: pearlson gd. Drug Alcohol Depend. 2018 Jul 1;188:71-78. doi: 10.1016/j.drugalcdep.2018.03.025. Epub 2018 Apr 26. Drug Alcohol Depend. 2018. PMID: 29754029 Free PMC article. Clinical Trial.
Marijuana (MJ) is widely used among college students, with peak use between ages 18-22. ...During recognition, MJ users showed less fMRI response than controls in right hippocampus (Cohen's d = 0.55), left hippocampus (Cohen's d = 0.67) and left IFG (Cohen'
Marijuana (MJ) is widely used among college students, with peak use between ages 18-22. ...During recognition, MJ users showed less f
Methodological factors as a potential source of discordance between self-report and behavioral measures of impulsivity and related constructs.
Ellingson JM, Potenza MN, Pearlson GD. Ellingson JM, et al. Among authors: pearlson gd. Addict Behav. 2018 Sep;84:126-130. doi: 10.1016/j.addbeh.2018.04.005. Epub 2018 Apr 9. Addict Behav. 2018. PMID: 29660594 Free PMC article.
College students were administered self-report questionnaires (Zuckerman Sensation Seeking Scale [ZSS], Barratt Impulsiveness Scale [BIS-11], behavioral measures related to risk-taking and impulsivity (Balloon Analog Risk Task [BART], Experiential Discounting Task [EDT]), and the …
College students were administered self-report questionnaires (Zuckerman Sensation Seeking Scale [ZSS], Barratt Impulsiveness Scale [BIS-11] …
Associations between adolescent cannabis use and brain structure in psychosis.
Abush H, Ghose S, Van Enkevort EA, Clementz BA, Pearlson GD, Sweeney JA, Keshavan MS, Tamminga CA, Ivleva EI. Abush H, et al. Among authors: pearlson gd. Psychiatry Res Neuroimaging. 2018 Jun 30;276:53-64. doi: 10.1016/j.pscychresns.2018.03.008. Epub 2018 Mar 28. Psychiatry Res Neuroimaging. 2018. PMID: 29628270 Free PMC article.
Associations between cannabis use and psychotic disorders suggest that cannabis may be a contributory risk factor in the neurobiology of psychosis. In this study, we examined brain structure characteristics, total and regional gray matter density (GMD), using Voxel …
Associations between cannabis use and psychotic disorders suggest that cannabis may be a contributory risk factor in the neuro …
S100A10 identified in a genome-wide gene cannabis dependence interaction analysis of risky sexual behaviours.
Polimanti R, Meda SA, Pearlson GD, Zhao H, Sherva R, Farrer LA, Kranzler HR, Gelernter J. Polimanti R, et al. Among authors: pearlson gd. J Psychiatry Neurosci. 2017 Jun;42(4):252-261. doi: 10.1503/jpn.160189. J Psychiatry Neurosci. 2017. PMID: 28418321 Free PMC article.
BACKGROUND: We conducted a genome-wide gene environment interaction analysis to identify genetic variants that interact with cannabis dependence (CaD) in influencing risky sexual behaviours (RSB). METHODS: Our sample included cannabis-exposed and sexually experience …
BACKGROUND: We conducted a genome-wide gene environment interaction analysis to identify genetic variants that interact with cannabis
Longitudinal influence of alcohol and marijuana use on academic performance in college students.
Meda SA, Gueorguieva RV, Pittman B, Rosen RR, Aslanzadeh F, Tennen H, Leen S, Hawkins K, Raskin S, Wood RM, Austad CS, Dager A, Fallahi C, Pearlson GD. Meda SA, et al. Among authors: pearlson gd. PLoS One. 2017 Mar 8;12(3):e0172213. doi: 10.1371/journal.pone.0172213. eCollection 2017. PLoS One. 2017. PMID: 28273162 Free PMC article.
METHODS: Data were derived from the longitudinal 2-year Brain and Alcohol Research in College Students (BARCS) study including 1142 freshman students who completed monthly marijuana use and alcohol consumption surveys. Subjects were classified into data-driven groups based …
METHODS: Data were derived from the longitudinal 2-year Brain and Alcohol Research in College Students (BARCS) study including 1142 freshman …
Cognitive Function in Individuals With Psychosis: Moderation by Adolescent Cannabis Use.
Hanna RC, Shalvoy A, Cullum CM, Ivleva EI, Keshavan M, Pearlson G, Hill SK, Sweeney JA, Tamminga CA, Ghose S. Hanna RC, et al. Among authors: pearlson g. Schizophr Bull. 2016 Nov;42(6):1496-1503. doi: 10.1093/schbul/sbw030. Epub 2016 Mar 31. Schizophr Bull. 2016. PMID: 27033329 Free PMC article.
Prior cannabis use, compared to nonuse, is reported to be associated with less cognitive impairment in schizophrenia. The age of cannabis use and the persistent influence of cannabis use on cognitive function has not been examined across the psychosis dimensi …
Prior cannabis use, compared to nonuse, is reported to be associated with less cognitive impairment in schizophrenia. The age of c
Multivariate analysis of subjective responses to d-amphetamine in healthy volunteers finds novel genetic pathway associations.
Yarosh HL, Meda SA, de Wit H, Hart AB, Pearlson GD. Yarosh HL, et al. Among authors: pearlson gd. Psychopharmacology (Berl). 2015 Aug;232(15):2781-94. doi: 10.1007/s00213-015-3914-1. Epub 2015 Apr 7. Psychopharmacology (Berl). 2015. PMID: 25843748 Free PMC article.
The second associated components included the "Anger" items from the Profile of Mood States (POMS) questionnaire and the marijuana effects from the Addiction Research Center Inventory (Cuyas, Verdejo-Garcia et al.), with enriched genetic pathways involved in cardiomyopathy …
The second associated components included the "Anger" items from the Profile of Mood States (POMS) questionnaire and the marijuana ef …
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