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Cannabis Use in Older Individuals May Be an Important and Under-Recognized Risk Factor for Motor Vehicle Crashes.
Pearlson GD, D'Souza DC, Marottoli RA, Stevens MC. Pearlson GD, et al. Cannabis Cannabinoid Res. 2026 Feb;11(1):5-10. doi: 10.1177/25785125251410814. Epub 2025 Dec 29. Cannabis Cannabinoid Res. 2026. PMID: 41467908 Review.
At the same time, an increasing number of older people are using cannabis for medical and recreational purposes. Cannabis (mostly due to its delta-9 tetrahydrocannabinol [THC] content) compromises sensory and neurocognitive abilities necessary for safe driving, and …
At the same time, an increasing number of older people are using cannabis for medical and recreational purposes. Cannabis (mos …
Cannabis, Aging and Cognition: An Urgent Need for Research.
D'Souza DC, Gupta P, Schnakenberg Martin AM, Stevens MC, Pearlson GD. D'Souza DC, et al. Among authors: pearlson gd. Cannabis Cannabinoid Res. 2026 Feb;11(1):1-4. doi: 10.1177/25785125251394916. Epub 2025 Nov 9. Cannabis Cannabinoid Res. 2026. PMID: 41204734 Free article. No abstract available.
A randomized, placebo-controlled, double-blind, pilot study of cannabis-related driving impairment assessed by driving simulator and self-report.
Meda SA, Stevens MC, Boer ER, Pittman B, Gueorguieva R, Huestis MA, Pearlson GD. Meda SA, et al. Among authors: pearlson gd. J Psychopharmacol. 2025 Apr;39(4):364-372. doi: 10.1177/02698811251324379. Epub 2025 Mar 12. J Psychopharmacol. 2025. PMID: 40077985 Clinical Trial.
AIMS: In the context of increasing cannabis use, understanding how cannabis affects specific driving behaviors is crucial in mitigating risks and ensuring road safety. ...CONCLUSIONS: Our study reveals for the first time long-lasting cannabis-induced impairme …
AIMS: In the context of increasing cannabis use, understanding how cannabis affects specific driving behaviors is crucial in m …
Identification and External Validation of a Problem Cannabis Risk Network.
Lichenstein SD, Kiluk BD, Potenza MN, Garavan H, Chaarani B, Banaschewski T, Bokde ALW, Desrivières S, Flor H, Grigis A, Gowland P, Heinz A, Brühl R, Martinot JL, Paillère Martinot ML, Artiges E, Nees F, Orfanos DP, Poustka L, Hohmann S, Holz N, Baeuchl C, Smolka MN, Vaidya N, Walter H, Whelan R, Schumann G, Pearlson G, Yip SW. Lichenstein SD, et al. Among authors: pearlson g. Biol Psychiatry. 2025 Oct 15;98(8):586-596. doi: 10.1016/j.biopsych.2025.01.022. Epub 2025 Feb 3. Biol Psychiatry. 2025. PMID: 39909136 Free PMC article.
We further examined whether the identified network would generalize to predict cannabis use in an independent sample of European adolescents/emerging adults (n = 1320, 53% female), whether it would predict clinical characteristics among adults seeking treatment for cann
We further examined whether the identified network would generalize to predict cannabis use in an independent sample of European adol …
Characterizing Cannabis Use and Perceived Benefit in a Tertiary Headache Center Patient Sample.
Starkey B, Pearlson GD, Bond D, Glaser C, Bhargava A, Grosberg BM, Verhaak A. Starkey B, et al. Among authors: pearlson gd. Neurol Clin Pract. 2024 Apr;14(2):e200285. doi: 10.1212/CPJ.0000000000200285. Epub 2024 Mar 6. Neurol Clin Pract. 2024. PMID: 38455123 Free PMC article.
Over half (58.0%) of the respondents reported only using cannabis products when experiencing a headache, while 42.0% used cannabis most days/daily for prevention. ...A minority (20.9%) of participants reported experiencing side effects when using cannabis pro …
Over half (58.0%) of the respondents reported only using cannabis products when experiencing a headache, while 42.0% used cannabis
Characterization of childhood trauma, hippocampal mediation and Cannabis use in a large dataset of psychosis and non-psychosis individuals.
Del Re EC, Yassin W, Zeng V, Keedy S, Alliey-Rodriguez N, Ivleva E, Hill S, Rychagov N, McDowell JE, Bishop JR, Mesholam-Gately R, Merola G, Lizano P, Gershon E, Pearlson G, Sweeney JA, Clementz B, Tamminga C, Keshavan M. Del Re EC, et al. Among authors: pearlson g. Schizophr Res. 2023 May;255:102-109. doi: 10.1016/j.schres.2023.03.029. Epub 2023 Mar 27. Schizophr Res. 2023. PMID: 36989667
BACKGROUND: Cannabis use (CA) and childhood trauma (CT) independently increase the risk of earlier psychosis onset; but their interaction in relation to psychosis risk and association with endocannabinoid-receptor rich brain regions, i.e. the hippocampus (HP), remains uncl …
BACKGROUND: Cannabis use (CA) and childhood trauma (CT) independently increase the risk of earlier psychosis onset; but their interac …
Consensus paper of the WFSBP task force on cannabis, cannabinoids and psychosis.
D'Souza DC, DiForti M, Ganesh S, George TP, Hall W, Hjorthøj C, Howes O, Keshavan M, Murray RM, Nguyen TB, Pearlson GD, Ranganathan M, Selloni A, Solowij N, Spinazzola E. D'Souza DC, et al. Among authors: pearlson gd. World J Biol Psychiatry. 2022 Dec;23(10):719-742. doi: 10.1080/15622975.2022.2038797. Epub 2022 Mar 22. World J Biol Psychiatry. 2022. PMID: 35315315 Review.
OBJECTIVES: The liberalisation of cannabis laws, the increasing availability and potency of cannabis has renewed concern about the risk of psychosis with cannabis. ...CONCLUSIONS: Given that exposure to cannabis and cannabinoids is modifiable, delaying …
OBJECTIVES: The liberalisation of cannabis laws, the increasing availability and potency of cannabis has renewed concern about …
Neuromodulation to Treat Substance Use Disorders in People With Schizophrenia and Other Psychoses: A Systematic Review.
Johnstone S, Sorkhou M, Al-Saghir N, Lowe DJE, Steele VR, Pearlson GD, Castle DJ, George TP. Johnstone S, et al. Among authors: pearlson gd. Front Psychiatry. 2022 Feb 14;13:793938. doi: 10.3389/fpsyt.2022.793938. eCollection 2022. Front Psychiatry. 2022. PMID: 35237187 Free PMC article.
RESULTS: Despite the limited number of studies in this area, the evidence suggests that rTMS to the dorsolateral prefrontal cortex (DLPFC) may reduce cannabis and tobacco use in patients with schizophrenia and schizoaffective disorder. Findings with tDCS, however, were inc …
RESULTS: Despite the limited number of studies in this area, the evidence suggests that rTMS to the dorsolateral prefrontal cortex (DLPFC) m …
Cannabis and Driving.
Pearlson GD, Stevens MC, D'Souza DC. Pearlson GD, et al. Front Psychiatry. 2021 Sep 24;12:689444. doi: 10.3389/fpsyt.2021.689444. eCollection 2021. Front Psychiatry. 2021. PMID: 34630173 Free PMC article. Review.
In this article we review in a focused manner, current information linking cannabis to motor vehicle accidents and examine patterns of cannabis-impairment of driving related behaviors, their time courses, relationship to cannabis dose and THC blood levels, an …
In this article we review in a focused manner, current information linking cannabis to motor vehicle accidents and examine patterns o …
Associations of cannabis use disorder with cognition, brain structure, and brain function in African Americans.
Koenis MMG, Durnez J, Rodrigue AL, Mathias SR, Alexander-Bloch AF, Barrett JA, Doucet GE, Frangou S, Knowles EEM, Mollon J, Denbow D, Aberizk K, Zatony M, Janssen RJ, Curran JE, Blangero J, Poldrack RA, Pearlson GD, Glahn DC. Koenis MMG, et al. Among authors: pearlson gd. Hum Brain Mapp. 2021 Apr 15;42(6):1727-1741. doi: 10.1002/hbm.25324. Epub 2020 Dec 19. Hum Brain Mapp. 2021. PMID: 33340172 Free PMC article.
Although previous studies have highlighted associations of cannabis use with cognition and brain morphometry, critical questions remain with regard to the association between cannabis use and brain structural and functional connectivity. ...In a large sample collect …
Although previous studies have highlighted associations of cannabis use with cognition and brain morphometry, critical questions rema …
23 results