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1986 1
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75 results

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Page 1
Peptides and Ageing.
Khavinson VKh. Khavinson VKh. Neuro Endocrinol Lett. 2002;23 Suppl 3:11-144. Neuro Endocrinol Lett. 2002. PMID: 12374906 Review.
Based on the data about the amino acid compositions of the peptide preparations, novel principles of the design of biologically active short peptides possessing tissue-specific activities has been developed. ...Based on three decades of studies of the peptide …
Based on the data about the amino acid compositions of the peptide preparations, novel principles of the design of biologically activ …
[Urotensin-related peptide--urocortin].
Imaki T, Tanabe A, Naruse M. Imaki T, et al. Nihon Rinsho. 2004 Sep;62 Suppl 9:735-40. Nihon Rinsho. 2004. PMID: 15506485 Review. Japanese. No abstract available.
In situ protein corona-camouflaged supramolecular assemblies remodel thrombotic microenvironment for improved arterial homeostasis.
Chen D, Chen Y, Liu J, Liu X, Liu P, Zhan J, Chen Z, Gan Y, Huang M, Chen Z. Chen D, et al. Sci Adv. 2025 May 2;11(18):eadu6676. doi: 10.1126/sciadv.adu6676. Epub 2025 May 2. Sci Adv. 2025. PMID: 40315315 Free PMC article.
To address this, small molecular inhibitors of PAI-1 and inflammation are used as bioregulators to restore vascular homeostasis. We design a carrier-free supramolecular system based on the bioregulators-tuned self-assembly of a near-infrared thrombus probe, which pr …
To address this, small molecular inhibitors of PAI-1 and inflammation are used as bioregulators to restore vascular homeostasis. We d …
RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function.
Shiraishi C, Matsumoto A, Ichihara K, Yamamoto T, Yokoyama T, Mizoo T, Hatano A, Matsumoto M, Tanaka Y, Matsuura-Suzuki E, Iwasaki S, Matsushima S, Tsutsui H, Nakayama KI. Shiraishi C, et al. Nat Commun. 2023 Apr 20;14(1):2131. doi: 10.1038/s41467-023-37838-6. Nat Commun. 2023. PMID: 37080962 Free PMC article.
Here we show that RPL3L, a paralog of RPL3 specifically expressed in heart and skeletal muscle, influences translation elongation dynamics. Deficiency of RPL3L-containing ribosomes in RPL3L knockout male mice resulted in impaired cardiac contractility. Ribosome occu …
Here we show that RPL3L, a paralog of RPL3 specifically expressed in heart and skeletal muscle, influences translation elongation dyn …
Senescence-Associated Secretory Phenotype of Cardiovascular System Cells and Inflammaging: Perspectives of Peptide Regulation.
Khavinson V, Linkova N, Dyatlova A, Kantemirova R, Kozlov K. Khavinson V, et al. Cells. 2022 Dec 27;12(1):106. doi: 10.3390/cells12010106. Cells. 2022. PMID: 36611900 Free PMC article. Review.
A senescence-associated secretory phenotype (SASP) and a mild inflammatory response characteristic of senescent cells (inflammaging) form the conditions for the development of cardiovascular diseases: atherosclerosis, coronary heart disease, and myocardial infarction. The …
A senescence-associated secretory phenotype (SASP) and a mild inflammatory response characteristic of senescent cells (inflammaging) form th …
[Geroprotective effect of thymalin and epithalamin].
Khavinson VKh, Morozov VG. Khavinson VKh, et al. Adv Gerontol. 2002;10:74-84. Adv Gerontol. 2002. PMID: 12577695 Review. Russian.
Researchers of the St. Petersburg Institute of Bioregulation and Gerontology of the North-Western Branch of the Russian Academy of Medical Sciences and the Research Institute of Gerontology of the Ukrainian Academy of Medical Sciences (Kiev) clinically assessed the geropro …
Researchers of the St. Petersburg Institute of Bioregulation and Gerontology of the North-Western Branch of the Russian Academy of Me …
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index.
Wen W, Zheng W, Okada Y, Takeuchi F, Tabara Y, Hwang JY, Dorajoo R, Li H, Tsai FJ, Yang X, He J, Wu Y, He M, Zhang Y, Liang J, Guo X, Sheu WH, Delahanty R, Guo X, Kubo M, Yamamoto K, Ohkubo T, Go MJ, Liu JJ, Gan W, Chen CC, Gao Y, Li S, Lee NR, Wu C, Zhou X, Song H, Yao J, Lee IT, Long J, Tsunoda T, Akiyama K, Takashima N, Cho YS, Ong RT, Lu L, Chen CH, Tan A, Rice TK, Adair LS, Gui L, Allison M, Lee WJ, Cai Q, Isomura M, Umemura S, Kim YJ, Seielstad M, Hixson J, Xiang YB, Isono M, Kim BJ, Sim X, Lu W, Nabika T, Lee J, Lim WY, Gao YT, Takayanagi R, Kang DH, Wong TY, Hsiung CA, Wu IC, Juang JM, Shi J, Choi BY, Aung T, Hu F, Kim MK, Lim WY, Wang TD, Shin MH, Lee J, Ji BT, Lee YH, Young TL, Shin DH, Chun BY, Cho MC, Han BG, Hwu CM, Assimes TL, Absher D, Yan X, Kim E, Kuo JZ, Kwon S, Taylor KD, Chen YD, Rotter JI, Qi L, Zhu D, Wu T, Mohlke KL, Gu D, Mo Z, Wu JY, Lin X, Miki T, Tai ES, Lee JY, Kato N, Shu XO, Tanaka T. Wen W, et al. Hum Mol Genet. 2014 Oct 15;23(20):5492-504. doi: 10.1093/hmg/ddu248. Epub 2014 May 26. Hum Mol Genet. 2014. PMID: 24861553 Free PMC article.
Protective Roles of Interferon-gamma in Cardiac Hypertrophy Induced by Sustained Pressure Overload.
Kimura A, Ishida Y, Furuta M, Nosaka M, Kuninaka Y, Taruya A, Mukaida N, Kondo T. Kimura A, et al. J Am Heart Assoc. 2018 Mar 19;7(6):e008145. doi: 10.1161/JAHA.117.008145. J Am Heart Assoc. 2018. PMID: 29555642 Free PMC article.
BACKGROUND: A clear understanding of the molecular mechanisms underlying hemodynamic stress-initiated cardiac hypertrophy is important for preventing heart failure. Interferon-gamma (IFN-gamma) has been suggested to play crucial roles in various diseases other than …
BACKGROUND: A clear understanding of the molecular mechanisms underlying hemodynamic stress-initiated cardiac hypertrophy is importan …
The PTHrP/PTH.1-R bioregulation system in cardiac hypertrophy: possible therapeutic implications.
Halapas A, Diamanti-Kandarakis E, Kremastinos D, Koutsilieris M. Halapas A, et al. In Vivo. 2006 Nov-Dec;20(6B):837-44. In Vivo. 2006. PMID: 17203776 Free article. Review.
Recently, the parathyroid hormone-related protein (PTHrP)/PTH-1 receptor (PTH-1.R) bioregulation system was shown to participate in specific regulatory processes of the cardiomyocyte function and proliferation, which can be related to cardiac hypertrophy and hear …
Recently, the parathyroid hormone-related protein (PTHrP)/PTH-1 receptor (PTH-1.R) bioregulation system was shown to participate in s …
75 results