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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
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1982 4
1983 11
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1993 44
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2002 115
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2005 137
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2007 129
2008 140
2009 142
2010 127
2011 139
2012 153
2013 159
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4,697 results

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Page 1
The Menopause Transition: Signs, Symptoms, and Management Options.
Santoro N, Roeca C, Peters BA, Neal-Perry G. Santoro N, et al. J Clin Endocrinol Metab. 2021 Jan 1;106(1):1-15. doi: 10.1210/clinem/dgaa764. J Clin Endocrinol Metab. 2021. PMID: 33095879 Free article. Review.
The endocrine tumult of the menopause transition also exposes racial and socioeconomic disparities in the onset, severity, and frequency of symptoms. Hormone therapy (HT) treatment can be effective for perimenopausal symptoms but its use has been stymied by c …
The endocrine tumult of the menopause transition also exposes racial and socioeconomic disparities in the onset, severity, and frequency of …
Management of perimenopausal and menopausal symptoms.
Duralde ER, Sobel TH, Manson JE. Duralde ER, et al. BMJ. 2023 Aug 8;382:e072612. doi: 10.1136/bmj-2022-072612. BMJ. 2023. PMID: 37553173 Review.
Most women worldwide experience menopausal symptoms during the menopause transition or postmenopause. Vasomotor symptoms are most pronounced during the first four to seven years but can persist for more than a decade, and genitourinary symptoms tend to be pro …
Most women worldwide experience menopausal symptoms during the menopause transition or postmenopause. Vasomotor symptoms are m …
Perimenopause as a neurological transition state.
Brinton RD, Yao J, Yin F, Mack WJ, Cadenas E. Brinton RD, et al. Nat Rev Endocrinol. 2015 Jul;11(7):393-405. doi: 10.1038/nrendo.2015.82. Epub 2015 May 26. Nat Rev Endocrinol. 2015. PMID: 26007613 Free PMC article. Review.
Although primarily viewed as a reproductive transition, the symptoms of perimenopause are largely neurological in nature. Neurological symptoms that emerge during perimenopause are indicative of disruption in multiple estrogen-regulated systems (includ …
Although primarily viewed as a reproductive transition, the symptoms of perimenopause are largely neurological in nature. Neur …
Perimenopause: From Research to Practice.
Santoro N. Santoro N. J Womens Health (Larchmt). 2016 Apr;25(4):332-9. doi: 10.1089/jwh.2015.5556. Epub 2015 Dec 10. J Womens Health (Larchmt). 2016. PMID: 26653408 Free PMC article. Review.
The menopausal transition, or perimenopause, is associated with profound reproductive and hormonal changes. These changes have been well chronicled and matched with concomitant symptoms. ...Unlike hot flashes, mood issues, and sleep, vaginal symptoms will not …
The menopausal transition, or perimenopause, is associated with profound reproductive and hormonal changes. These changes have been w …
Perimenopause: Symptoms, work ability and health among 4010 Dutch workers.
Oude Hengel KM, Soeter M, In der Maur M, van Oostrom SH, Loef B, Hooftman WE. Oude Hengel KM, et al. Maturitas. 2023 Oct;176:107793. doi: 10.1016/j.maturitas.2023.107793. Epub 2023 Jun 23. Maturitas. 2023. PMID: 37393659 Free article.
RESULTS: Almost one-fifth of participants were in the perimenopause (n = 743). Of these women, 80 % experienced menopausal symptoms: 27.5 % 'often' and 52.5 % 'sometimes'. ...These associations were most pronounced among perimenopausal women 'often' experienc …
RESULTS: Almost one-fifth of participants were in the perimenopause (n = 743). Of these women, 80 % experienced menopausal symptom …
Perimenopausal abnormal uterine bleeding.
Dreisler E, Frandsen CS, Ulrich L. Dreisler E, et al. Maturitas. 2024 Jun;184:107944. doi: 10.1016/j.maturitas.2024.107944. Epub 2024 Feb 22. Maturitas. 2024. PMID: 38412750 Free article. Review.
Abnormal uterine bleeding is a frequent symptom in the perimenopause. Causes are numerous, ranging from physiological reactions due to decreasing/unstable ovarian function to premalignant and malignant conditions. ...Endometrial ablation or endometrial resection are …
Abnormal uterine bleeding is a frequent symptom in the perimenopause. Causes are numerous, ranging from physiological reaction …
Effect of transdermal testosterone therapy on mood and cognitive symptoms in peri- and postmenopausal women: a pilot study.
Glynne S, Kamal A, Kamel AM, Reisel D, Newson L. Glynne S, et al. Arch Womens Ment Health. 2025 Jun;28(3):541-550. doi: 10.1007/s00737-024-01513-6. Epub 2024 Sep 16. Arch Womens Ment Health. 2025. PMID: 39283522 Free PMC article.
PURPOSE: The purpose of this study was to assess the impact of testosterone therapy on mood and cognitive symptoms in perimenopausal and postmenopausal women. METHODS: A retrospective cohort study undertaken in a UK specialist menopause clinic. 510 women using hormo …
PURPOSE: The purpose of this study was to assess the impact of testosterone therapy on mood and cognitive symptoms in perimenopaus …
Prevalence and severity of symptoms across the menopause transition: cross-sectional findings from the Australian Women's Midlife Years (AMY) Study.
Islam RM, Bond M, Ghalebeigi A, Wang Y, Walker-Bone K, Davis SR. Islam RM, et al. Lancet Diabetes Endocrinol. 2025 Sep;13(9):765-776. doi: 10.1016/S2213-8587(25)00138-X. Epub 2025 Jul 25. Lancet Diabetes Endocrinol. 2025. PMID: 40720963
Less variation was apparent for other symptoms, including poor memory and low mood. Vaginal dryness was the most discriminative sexual symptom from premenopause to late perimenopause (adjusted prevalence ratio 2.54 [95% CI 1.78-3.61]). ...Compared with premen …
Less variation was apparent for other symptoms, including poor memory and low mood. Vaginal dryness was the most discriminative sexua …
Effects of combined estrogen and bazedoxifene (CEB) on depressive symptoms in perimenopause.
Bondy E, Prim J, Rubinow D, Schiff L, Dichter GS, Schiller CE. Bondy E, et al. J Affect Disord. 2025 Dec 1;390:119853. doi: 10.1016/j.jad.2025.119853. Epub 2025 Jul 7. J Affect Disord. 2025. PMID: 40633782 Clinical Trial.
Conjugated estrogen combined with the selective estrogen receptor modulator (SERM) bazedoxifene (CEB) is a tissue selective estrogen complex (TSEC) used to target hot flashes and postmenopausal osteoporosis. CEB's effect on mood during perimenopause remains understudied. M …
Conjugated estrogen combined with the selective estrogen receptor modulator (SERM) bazedoxifene (CEB) is a tissue selective estrogen complex …
Perimenopausal symptoms in women with and without ADHD: A population-based cohort study.
Jakobsdóttir Smári U, Valdimarsdottir UA, Wynchank D, de Jong M, Aspelund T, Hauksdottir A, Thordardottir EB, Tomasson G, Jakobsdottir J, Lu D, Nevriana A, Larsson H, Kooij S, Zoega H. Jakobsdóttir Smári U, et al. Eur Psychiatry. 2025 Sep 4;68(1):e133. doi: 10.1192/j.eurpsy.2025.10101. Eur Psychiatry. 2025. PMID: 40903825 Free PMC article.
BACKGROUND: Knowledge of the impact of perimenopause on women with attention-deficit/hyperactivity disorder (ADHD) is lacking. We compared levels of perimenopausal symptoms and prevalence of severe perimenopausal symptoms among women with and wi …
BACKGROUND: Knowledge of the impact of perimenopause on women with attention-deficit/hyperactivity disorder (ADHD) is lacking. We com …
4,697 results