Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 2
1988 1
1989 10
1990 7
1991 7
1992 8
1993 12
1994 8
1995 11
1996 8
1997 7
1998 11
1999 17
2000 14
2001 28
2002 16
2003 27
2004 23
2005 24
2006 24
2007 33
2008 27
2009 36
2010 27
2011 16
2012 14
2013 17
2014 21
2015 22
2016 21
2017 5
2018 7
2019 11
2020 9
2021 6
2022 10
2023 7
2024 2

Text availability

Article attribute

Article type

Publication date

Search Results

517 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
The perindopril in elderly people with chronic heart failure (PEP-CHF) study.
Cleland JG, Tendera M, Adamus J, Freemantle N, Polonski L, Taylor J; PEP-CHF Investigators. Cleland JG, et al. Eur Heart J. 2006 Oct;27(19):2338-45. doi: 10.1093/eurheartj/ehl250. Epub 2006 Sep 8. Eur Heart J. 2006. PMID: 16963472 Clinical Trial.
Overall, 107 patients assigned to placebo and 100 assigned to perindopril reached the primary endpoint (HR 0.919: 95% CI 0.700-1.208; P = 0.545). By 1 year, reductions in the primary outcome (HR 0.692: 95% CI 0.474-1.010; P = 0.055) and hospitalization for heart failure (H …
Overall, 107 patients assigned to placebo and 100 assigned to perindopril reached the primary endpoint (HR 0.919: 95% CI 0.700-1.208; …
Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study).
Fox KM; EURopean trial On reduction of cardiac events with Perindopril in stable coronary Artery disease Investigators. Fox KM, et al. Lancet. 2003 Sep 6;362(9386):782-8. doi: 10.1016/s0140-6736(03)14286-9. Lancet. 2003. PMID: 13678872 Clinical Trial.
After a run-in period of 4 weeks, in which all patients received perindopril, 12218 patients were randomly assigned perindopril 8 mg once daily (n=6110), or matching placebo (n=6108). ...These benefits were consistent in all predefined subgroups and secondary endpoi …
After a run-in period of 4 weeks, in which all patients received perindopril, 12218 patients were randomly assigned perindopril
Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.
PROGRESS Collaborative Group. PROGRESS Collaborative Group. Lancet. 2001 Sep 29;358(9287):1033-41. doi: 10.1016/S0140-6736(01)06178-5. Lancet. 2001. PMID: 11589932 Clinical Trial.
Active treatment comprised a flexible regimen based on the angiotensin- converting-enzyme inhibitor perindopril (4 mg daily), with the addition of the diuretic indapamide at the discretion of treating physicians. ...INTERPRETATION: This blood-pressure-lowering regimen redu …
Active treatment comprised a flexible regimen based on the angiotensin- converting-enzyme inhibitor perindopril (4 mg daily), with th …
Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial.
Dahlöf B, Sever PS, Poulter NR, Wedel H, Beevers DG, Caulfield M, Collins R, Kjeldsen SE, Kristinsson A, McInnes GT, Mehlsen J, Nieminen M, O'Brien E, Ostergren J; ASCOT Investigators. Dahlöf B, et al. Lancet. 2005 Sep 10-16;366(9489):895-906. doi: 10.1016/S0140-6736(05)67185-1. Lancet. 2005. PMID: 16154016 Clinical Trial.
Our aim, therefore, was to compare the effect on non-fatal myocardial infarction and fatal CHD of combinations of atenolol with a thiazide versus amlodipine with perindopril. METHODS: We did a multicentre, prospective, randomised controlled trial in 19 257 patients with hy …
Our aim, therefore, was to compare the effect on non-fatal myocardial infarction and fatal CHD of combinations of atenolol with a thiazide v …
Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
Patel A; ADVANCE Collaborative Group; MacMahon S, Chalmers J, Neal B, Woodward M, Billot L, Harrap S, Poulter N, Marre M, Cooper M, Glasziou P, Grobbee DE, Hamet P, Heller S, Liu LS, Mancia G, Mogensen CE, Pan CY, Rodgers A, Williams B. Patel A, et al. Lancet. 2007 Sep 8;370(9590):829-40. doi: 10.1016/S0140-6736(07)61303-8. Lancet. 2007. PMID: 17765963 Clinical Trial.
After a 6-week active run-in period, 11 140 patients with type 2 diabetes were randomised to treatment with a fixed combination of perindopril and indapamide or matching placebo, in addition to current therapy. ...INTERPRETATION: Routine administration of a fixed combinati …
After a 6-week active run-in period, 11 140 patients with type 2 diabetes were randomised to treatment with a fixed combination of perind
Evaluation of the Safety and Efficacy of Dual Therapy Perindopril/Amlodipine in the Management of Hypertension. A Systematic Review and Meta-Analysis.
Mostafa S, Shabana H, Khalil F, Mancy IME, Zedan HA, Elmoursi A, Ramadan IG, Mohamed SED, Kassem A, Kamel IS. Mostafa S, et al. High Blood Press Cardiovasc Prev. 2022 Nov;29(6):565-576. doi: 10.1007/s40292-022-00544-3. Epub 2022 Oct 26. High Blood Press Cardiovasc Prev. 2022. PMID: 36287359 Review.
Hypertension is classified into two types which are primary or essential hypertension and secondary hypertension. The perindopril-amlodipine combination showed a significant effect in reduction of the elevated BP and the cardiovascular complications. AIM: To evaluate the e …
Hypertension is classified into two types which are primary or essential hypertension and secondary hypertension. The perindopril-aml …
Perindopril: do randomised, controlled trials support an ACE inhibitor class effect? A meta-analysis of clinical trials.
Snyman JR, Wessels F. Snyman JR, et al. Cardiovasc J Afr. 2009 Mar-Apr;20(2):127-34. Cardiovasc J Afr. 2009. PMID: 19421649 Free PMC article. Review.
This meta-analysis was performed using odds ratios as the parameter of efficacy in a fixed-effects model. RESULTS/CONCLUSION: Perindopril resulted in significantly fewer patients reaching the primary endpoint versus all other ACEIs combined. ...In the presence of positive …
This meta-analysis was performed using odds ratios as the parameter of efficacy in a fixed-effects model. RESULTS/CONCLUSION: Perindopril
Antihypertensive effect of telmisartan versus perindopril in hypertensive patients.
Zhao D, Liu H, Chen S, Dong P. Zhao D, et al. Bratisl Lek Listy. 2023;124(5):380-386. doi: 10.4149/BLL_2023_058. Bratisl Lek Listy. 2023. PMID: 36876369
OBJECTIVE: We performed this meta-analysis determining the antihypertensive effect of telmisartan versus perindopril in patients with essential hypertension. BACKGROUND: The comparison of antihypertensive effects between telmisartan and perindopril were controversia …
OBJECTIVE: We performed this meta-analysis determining the antihypertensive effect of telmisartan versus perindopril in patients with …
A randomized trial of genotype-guided perindopril use.
Lee SH, Lee CJ, Kang Y, Park JM, Lee JH. Lee SH, et al. J Hypertens. 2023 Nov 1;41(11):1768-1774. doi: 10.1097/HJH.0000000000003536. Epub 2023 Aug 17. J Hypertens. 2023. PMID: 37602458 Clinical Trial.
This randomized trial investigated whether genotype-guided perindopril use could reduce drug-related cough in 20 to 79-year-old individuals with hypertension. ...The high-risk subgroup received candesartan (8 mg/day) for 6 weeks, whereas the low-risk subgroup received p
This randomized trial investigated whether genotype-guided perindopril use could reduce drug-related cough in 20 to 79-year-old indiv …
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
Xie M, Tang T, Liang H. Xie M, et al. Clin Cardiol. 2023 Aug;46(8):886-898. doi: 10.1002/clc.24082. Epub 2023 Jul 11. Clin Cardiol. 2023. PMID: 37432701 Free PMC article. Review.
The results of the network meta-analysis showed that a total of 11 single-pill combination antihypertensive drugs were included, namely: Amlodipine/valsartan, Telmisartan/amlodipine, Losartan/HCTZ, Candesartan/HCTZ, Amlodipine/benazepril, Telmisartan/HCTZ, Valsartan/HCTZ, Irbesar …
The results of the network meta-analysis showed that a total of 11 single-pill combination antihypertensive drugs were included, namely: Aml …
517 results