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Antioxidant compounds of Petasites japonicus and their preventive effects in chronic diseases: a review.
Hiemori-Kondo M. Hiemori-Kondo M. J Clin Biochem Nutr. 2020 Jul;67(1):10-18. doi: 10.3164/jcbn.20-58. Epub 2020 Jun 11. J Clin Biochem Nutr. 2020. PMID: 32801463 Free PMC article. Review.
Petasites japonicus (P. japonicus) is a plant of the Asteraceae family. ...The study of the antioxidant activity of P. japonicus was initiated approximately 15 years ago using in vitro assays. ...
Petasites japonicus (P. japonicus) is a plant of the Asteraceae family. ...The study of the antioxidant activity of P.
Petasites japonicus extract exerts anti-malarial effects by inhibiting platelet activation.
Yun HS, Dinzouna-Boutamba SD, Lee S, Moon Z, Kwak D, Chung DI, Hong Y, Rhee MH, Goo YK. Yun HS, et al. Phytomedicine. 2022 Jul 20;102:154167. doi: 10.1016/j.phymed.2022.154167. Epub 2022 May 13. Phytomedicine. 2022. PMID: 35598522
In the pathology of cerebral malaria, platelets play a central role by binding infected and uninfected red cells and the endothelium. Since Petasites japonicus extract was reported as an effective inhibitor of platelet activation, we examined the antimalarial activi …
In the pathology of cerebral malaria, platelets play a central role by binding infected and uninfected red cells and the endothelium. Since …
Petasites japonicus leaf extract inhibits Alzheimer's-like pathology through suppression of neuroinflammation.
Eo H, Lee S, Kim SH, Ju IG, Huh E, Lim J, Park S, Oh MS. Eo H, et al. Food Funct. 2022 Oct 17;13(20):10811-10822. doi: 10.1039/d2fo01989b. Food Funct. 2022. PMID: 36193798
Neuroinflammation is a crucial pathogenic process involved in the development and deterioration of Alzheimer's disease (AD). Petasites japonicus is known for its beneficial effects on various disease states such as allergic reaction, oxidative stress and inflammatio …
Neuroinflammation is a crucial pathogenic process involved in the development and deterioration of Alzheimer's disease (AD). Petasites
Petasites japonicus Stimulates the Proliferation of Mouse Spermatogonial Stem Cells.
Kang HR, Lee YA, Kim YH, Lee DG, Kim BJ, Kim KJ, Kim BG, Oh MG, Han CK, Lee S, Ryu BY. Kang HR, et al. PLoS One. 2015 Jul 24;10(7):e0133077. doi: 10.1371/journal.pone.0133077. eCollection 2015. PLoS One. 2015. PMID: 26207817 Free PMC article.
In this study, we evaluated the effect of several natural plants on the preservation of male fertility by assessing the ability of plant extracts to stimulate spermatogonial stem cell (SSC) proliferation by using a serum-free culture method. In vitro assays showed that Petasit
In this study, we evaluated the effect of several natural plants on the preservation of male fertility by assessing the ability of plant ext …
Aqueous extract of Petasites japonicus leaves promotes osteoblast differentiation via up-regulation of Runx2 and Osterix in MC3T3-E1 cells.
Kim EJ, Jung JI, Jeon YE, Lee HS. Kim EJ, et al. Nutr Res Pract. 2021 Oct;15(5):579-590. doi: 10.4162/nrp.2021.15.5.579. Epub 2021 Apr 27. Nutr Res Pract. 2021. PMID: 34603606 Free PMC article.
BACKGROUND/OBJECTIVES: Petasites japonicus Maxim (P. japonicus) has been used as an edible and medicinal plant and contains many bioactive compounds. The purpose of this study is to investigate the effect of P. japonicus on osteogenesis. MATERIALS/METH …
BACKGROUND/OBJECTIVES: Petasites japonicus Maxim (P. japonicus) has been used as an edible and medicinal plant and cont …
Petasin is the main component responsible for the anti-adipogenic effect of Petasites japonicus.
Uesugi S, Hakozaki M, Kanno Y, Shiraishi A, Suzuki M, Kimura KI, Shiono Y, Yano A. Uesugi S, et al. Fitoterapia. 2022 Mar;157:105130. doi: 10.1016/j.fitote.2022.105130. Epub 2022 Jan 18. Fitoterapia. 2022. PMID: 35051554
Petasites japonicus is one of the most popular edible wild plants in Japan. Many biological effects of P. japonicus have been reported, including anti-allergy, anti-inflammation, and anticancer effects. ...
Petasites japonicus is one of the most popular edible wild plants in Japan. Many biological effects of P. japonicus hav
The complete chloroplast genome of Petasites japonicus (Siebold & Zucc.) Maxim. (Asteraceae).
Hashimoto T, Tsubota H, Shimamura M, Inoue Y. Hashimoto T, et al. Mitochondrial DNA B Resour. 2021 Nov 29;6(12):3503-3505. doi: 10.1080/23802359.2021.2005476. eCollection 2021. Mitochondrial DNA B Resour. 2021. PMID: 34869892 Free PMC article.
The complete chloroplast (cp) genome sequence of Petasites japonicus (Asteraceae) was determined. The cp genome is 150,445 bp and consists of a large single-copy region (82,910 bp), a small single-copy region (17,907 bp), and a pair of inverted repeats (24,814 bp). …
The complete chloroplast (cp) genome sequence of Petasites japonicus (Asteraceae) was determined. The cp genome is 150,445 bp …
Petasites japonicus bakkenolide B inhibits lipopolysaccharide-induced pro-inflammatory cytokines via AMPK/Nrf2 induction in microglia.
Park SY, Choi MH, Park G, Choi YW. Park SY, et al. Int J Mol Med. 2018 Mar;41(3):1683-1692. doi: 10.3892/ijmm.2017.3350. Epub 2017 Dec 28. Int J Mol Med. 2018. PMID: 29286084
Microglia regulate these responses via molecular signaling cascades that involve inflammatory cytokines and complement proteins. Bakkenolide B from Petasites japonicus exhibits significant anti-inflammatory and anti-allergic bioactivities. ...
Microglia regulate these responses via molecular signaling cascades that involve inflammatory cytokines and complement proteins. Bakkenolide …
S-Petasin isolated from Petasites japonicus exerts anti-adipogenic activity in the 3T3-L1 cell line by inhibiting PPAR-gamma pathway signaling.
Guo L , Li K , Cui ZW , Kang JS , Son BG , Choi YW . Guo L , et al. Food Funct. 2019 Jul 17;10(7):4396-4406. doi: 10.1039/c9fo00549h. Food Funct. 2019. PMID: 31282906
S-Petasin has been isolated from Petasites hybridus (L.), Petasites officinalis (L.) and Petasites formosanus, but not from Petasites japonicus. In this study, we found that hexane extracts of Petasites japonicus inhibited adipogen …
S-Petasin has been isolated from Petasites hybridus (L.), Petasites officinalis (L.) and Petasites formosanus, but not …
New otonecine-type pyrrolizidine alkaloid from Petasites japonicus.
Kitajima M, Okabe K, Yoshida M, Nakabayashi R, Saito K, Kogure N, Takayama H. Kitajima M, et al. J Nat Med. 2019 Jun;73(3):602-607. doi: 10.1007/s11418-019-01285-9. Epub 2019 Feb 19. J Nat Med. 2019. PMID: 30784002
One new otonecine-type pyrrolizidine alkaloid secopetasitenine (1), along with petasitenine (fukinotoxine, 2), neopetasitenine (3), and senkirkine (4), was isolated from the whole plant of Petasites japonicus. The structure of 1 was determined by spectroscopic analy …
One new otonecine-type pyrrolizidine alkaloid secopetasitenine (1), along with petasitenine (fukinotoxine, 2), neopetasitenine (3), and senk …
72 results