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1,972 results

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Page 1
Phage evolution and ecology.
Abedon ST. Abedon ST. Adv Appl Microbiol. 2009;67:1-45. doi: 10.1016/S0065-2164(08)01001-0. Adv Appl Microbiol. 2009. PMID: 19245935 Review.
Bacteriophages (phages) are the viruses of bacteria and the study of phage biology can be differentiated, roughly, into molecular, environmental, evolutionary, ecological, and applied aspects. ...In this chapter I jump into this latter void, providing an over
Bacteriophages (phages) are the viruses of bacteria and the study of phage biology can be differentiated, roughly, into
Community context matters for bacteria-phage ecology and evolution.
Blazanin M, Turner PE. Blazanin M, et al. ISME J. 2021 Nov;15(11):3119-3128. doi: 10.1038/s41396-021-01012-x. Epub 2021 Jun 14. ISME J. 2021. PMID: 34127803 Free PMC article. Review.
Bacteria-phage symbioses are ubiquitous in nature and serve as valuable biological models. Historically, the ecology and evolution of bacteria-phage systems have been studied in either very simple or very complex communities. ...Generally, community presence …
Bacteria-phage symbioses are ubiquitous in nature and serve as valuable biological models. Historically, the ecology and evolu …
Phage-host coevolution in natural populations.
Piel D, Bruto M, Labreuche Y, Blanquart F, Goudenège D, Barcia-Cruz R, Chenivesse S, Le Panse S, James A, Dubert J, Petton B, Lieberman E, Wegner KM, Hussain FA, Kauffman KM, Polz MF, Bikard D, Gandon S, Rocha EPC, Le Roux F. Piel D, et al. Nat Microbiol. 2022 Jul;7(7):1075-1086. doi: 10.1038/s41564-022-01157-1. Epub 2022 Jun 27. Nat Microbiol. 2022. PMID: 35760840 Free article.
Coevolution between bacteriophages (phages) and their bacterial hosts occurs through changes in resistance and counter-resistance mechanisms. ...Cross-infection studies of 81,926 host-phage pairs delineated a modular network where phages are best at in …
Coevolution between bacteriophages (phages) and their bacterial hosts occurs through changes in resistance and counter-resista …
Host receptors for bacteriophage adsorption.
Bertozzi Silva J, Storms Z, Sauvageau D. Bertozzi Silva J, et al. FEMS Microbiol Lett. 2016 Feb;363(4):fnw002. doi: 10.1093/femsle/fnw002. Epub 2016 Jan 10. FEMS Microbiol Lett. 2016. PMID: 26755501 Review.
The adsorption of bacteriophages (phages) onto host cells is, in all but a few rare cases, a sine qua non condition for the onset of the infection process. ...Comprehension of the whole infection process, starting with the adsorption step, can enable and accelerate …
The adsorption of bacteriophages (phages) onto host cells is, in all but a few rare cases, a sine qua non condition for the on …
Basic Phage Mathematics.
Abedon ST, Katsaounis TI. Abedon ST, et al. Methods Mol Biol. 2018;1681:3-30. doi: 10.1007/978-1-4939-7343-9_1. Methods Mol Biol. 2018. PMID: 29134583 Review.
Basic mathematical descriptions are useful in phage ecology, applied phage ecology such as in the course of phage therapy, and also toward keeping track of expected phage-bacterial interactions as seen during laboratory manipulation of …
Basic mathematical descriptions are useful in phage ecology, applied phage ecology such as in the course of p
Temperature as a Driver of Phage Ecology and Evolution.
Greenrod STE, Hector TE, Blazanin M, Cazares D, King KC. Greenrod STE, et al. Annu Rev Microbiol. 2025 Oct;79(1):497-522. doi: 10.1146/annurev-micro-042424-040029. Annu Rev Microbiol. 2025. PMID: 41130917 Free article. Review.
Bacteriophages (phages) are virtually ubiquitous and play a fundamental role in the ecological and evolutionary dynamics of their bacterial hosts. ...We then explore the potential effects of thermal variation on phage functions in natural microbial communitie
Bacteriophages (phages) are virtually ubiquitous and play a fundamental role in the ecological and evolutionary dynamics of th
Prediction of strain level phage-host interactions across the Escherichia genus using only genomic information.
Gaborieau B, Vaysset H, Tesson F, Charachon I, Dib N, Bernier J, Dequidt T, Georjon H, Clermont O, Hersen P, Debarbieux L, Ricard JD, Denamur E, Bernheim A. Gaborieau B, et al. Nat Microbiol. 2024 Nov;9(11):2847-2861. doi: 10.1038/s41564-024-01832-5. Epub 2024 Oct 31. Nat Microbiol. 2024. PMID: 39482383
Predicting bacteriophage infection of specific bacterial strains promises advancements in phage therapy and microbial ecology. Whether the dynamics of well-established phage-host model systems generalize to the wide diversity of microbes is currently unknown. …
Predicting bacteriophage infection of specific bacterial strains promises advancements in phage therapy and microbial ecology. …
The Biology of CRISPR-Cas: Backward and Forward.
Hille F, Richter H, Wong SP, Bratovič M, Ressel S, Charpentier E. Hille F, et al. Cell. 2018 Mar 8;172(6):1239-1259. doi: 10.1016/j.cell.2017.11.032. Cell. 2018. PMID: 29522745 Free article. Review.
In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins constitute an adaptive immune system against phages and other foreign genetic elements. Here, we review the biology of the diverse CRISPR-Cas sy …
In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins constitute …
Targeting Pseudomonas aeruginosa biofilm with an evolutionary trained bacteriophage cocktail exploiting phage resistance trade-offs.
Kunisch F, Campobasso C, Wagemans J, Yildirim S, Chan BK, Schaudinn C, Lavigne R, Turner PE, Raschke MJ, Trampuz A, Gonzalez Moreno M. Kunisch F, et al. Nat Commun. 2024 Oct 3;15(1):8572. doi: 10.1038/s41467-024-52595-w. Nat Commun. 2024. PMID: 39362854 Free PMC article.
Our two-phage cocktail reveals further improved antimicrobial efficacy without incurring dual-bacteriophage-resistance in treated bacteria. We anticipate this assay will allow a better understanding of phenotypic-genomic relationships in bacteriophages and enable th …
Our two-phage cocktail reveals further improved antimicrobial efficacy without incurring dual-bacteriophage-resistance in treated bac …
Phage therapy pharmacology.
Abedon ST, Thomas-Abedon C. Abedon ST, et al. Curr Pharm Biotechnol. 2010 Jan;11(1):28-47. doi: 10.2174/138920110790725410. Curr Pharm Biotechnol. 2010. PMID: 20214606 Review.
Any analysis of these steps is inherently ecological as they represent phage-environment interactions, i.e., between phages and bacteria as well as between phages and body tissues. ...Our primary conclusions are (i) that the principle advantages of phages
Any analysis of these steps is inherently ecological as they represent phage-environment interactions, i.e., between phages an …
1,972 results